ras Guanine Nucleotide Exchange FactorsSon of Sevenless Proteinsras-GRF1Guanine Nucleotide Exchange Factorsras ProteinsGRB2 Adaptor ProteinAmino Acid MotifsGenes, rasProto-Oncogene Proteins p21(ras)Molecular Sequence DataOncogene Protein p21(ras)Amino Acid SequenceNucleotide Motifsras GTPase-Activating ProteinsBase SequenceProtein BindingBinding SitesDeuterium Exchange MeasurementPulmonary Gas ExchangeSignal TransductionProtein Structure, TertiaryMutationExchange Transfusion, Whole BloodSister Chromatid ExchangeCell LineKineticsSequence Homology, Amino AcidModels, MolecularSequence AlignmentCells, CulturedTransfectionConserved SequenceRecombinant Fusion ProteinsPhosphorylationTranscription FactorsMutagenesis, Site-DirectedRecombinant ProteinsDNA-Binding ProteinsProteinsGuanosine DiphosphateModels, BiologicalProto-Oncogene Proteins c-rafCarrier ProteinsGuanosine TriphosphateProtein ConformationProtein Interaction Domains and MotifsCloning, MolecularHydrogenHydrogen-Ion ConcentrationCalciumGene Expression RegulationEnzyme ActivationTime FactorsSodium-Hydrogen AntiporterRNA, MessengerTranscription, GeneticDNAPromoter Regions, GeneticCell MembraneSodiumMembrane ProteinsProtein Structure, SecondaryGTPase-Activating ProteinsEscherichia coliGTP-Binding ProteinsStructure-Activity RelationshipCOS CellsChromatography, Ion ExchangeRho Guanine Nucleotide Exchange FactorsSaccharomyces cerevisiaeMagnetic Resonance SpectroscopyPeptidesHelix-Turn-Helix MotifsDeuterium3T3 CellsNeuronsRats, Sprague-Dawleyrap GTP-Binding ProteinsDose-Response Relationship, DrugDNA PrimersProto-Oncogene ProteinsHeLa CellsBacterial ProteinsPlasmidsProtein TransportAdenosine TriphosphateEnzyme InhibitorsNuclear ProteinsConsensus SequenceSaccharomyces cerevisiae ProteinsCell Transformation, NeoplasticSodium-Calcium ExchangerBlotting, WesternGTP PhosphohydrolasesBiological TransportSubstrate SpecificityProtein-Serine-Threonine KinasesMutagenesisIon Exchange Resinsral Guanine Nucleotide Exchange Factor