Moderately differentiated cases poorly differentiated. Medical search. Frequent questions

CD56 is a sensitive marker of ovarian sex cord-stromal tumors and may also be useful in the diagnosis of this group of neoplasms, especially in cases that are inhibin or calretinin negative, and the differential diagnosis includes neoplasms that are CD56 negative. (medscape.com)
Most FA's are well or moderately differentiated tumors, although high-grade, poorly differentiated variants have been described. (wikipedia.org)
In such cases, these biphasic tumors are classified as a form of pulmonary blastoma because the presence of the blastomatous cells dramatically worsens the prognosis. (wikipedia.org)
We identified 83 and 7 cases with well to moderately and poorly differentiated tumors, respectively. (breastcancertalk.net)
A single-institution retrospective review identified 45 cases of neuroendocrine (carcinoid) tumors in children and adolescents between 2003 and 2016. (oncolink.org)
Level of evidence C1] Primary re-excision was not recommended for completely excised tumors smaller than 2 cm except for microscopic/macroscopic residual tumor on the margins of the appendix, in which case cecum resection and pericecal node biopsy was recommended. (oncolink.org)
The study concluded that appendectomy alone should be considered curative for most cases of appendiceal neuroendocrine tumors. (oncolink.org)
A systematic review and meta-analysis of 38 studies of appendiceal neuroendocrine tumors identified 958 cases with a mean age at presentation of 11.6 years. (oncolink.org)
Another aim of this study was to differentiate the simple and adenocarcinoma tumors from the complex or mixed tumor described by Elston and Ellis grading method. (biomedcentral.com)
Moreover, we found that lesser differentiated tumors expressed higher miR-224 (P = 0.03). (kipdf.com)
Waterfowl may develop tumors in areas that are poorly feathered, suggesting an association with exposure to sunlight. (ivis.org)
In a number of cases, neuroendocrine tumors have both neurogenic and endocrine elements. (medscape.com)
OSCC of non-smokers were well-differentiated tumors in 50% of the cases, and those of smokers were equally distributed into moderately differentiated and poorly differentiated tumors (35.3% each). (knoblauchpublishing.com)
In most cases, histopathologic analysis will permit classification of these tumors into those with a favorable prognosis, which are mostly approached with locoregional treatment or systemic platinum-based chemotherapy, or an unfavorable prognosis, which are treated with empirical combination regimens involiving platinum or taxane. (medscape.com)

HMGCS2 protein expression is down-regulated preferentially in moderately and poorly differentiated carcinomas. (aacrjournals.org)
It demonstrated only weak focal staining of poorly differentiated carcinomas. (elsevierpure.com)
In the stromal cells a decline in Androgen Receptor expression was also noted but this decline was more pronounced and statistically significant correlation of Androgen Receptor expression was noted between well differentiated carcinomas and moderately and poorly differentiated prostatic carcinomas. (journalcra.com)
Molecular and cytogenetic studies in the diagnosis of patients with poorly differentiated carcinomas of unknown primary site. (medscape.com)

Biological assays were performed on well-[Ishikawa (ISH)] moderately (MFE-296) and poorly (MFE-280) differentiated human adenocarcinoma cancer cell lines, representing the G1, G2 and G3 stage of EC. (spandidos-publications.com)
Mice were immunized with human pancreatic adenocarcinoma cells and monoclonal antibodies were screened against a panel of archived pancreatic tissue sections, including pancreatitis (23 cases), grade 1 IPMN (16 cases), grade 2 IPMN (9 cases), grade 3 IPMN (13 cases), and various grades of adenocarcinoma (17 cases). (elsevierpure.com)
[ 3 , 4 ] The term "pseudomesotheliomatous carcinoma" was first applied by Harwood and colleagues in 1976 to 6 cases of peripheral lung adenocarcinoma that closely mimicked mesothelioma. (medscape.com)

A case of combined small cell lung carcinoma featuring components of FA and cells resembling those from carcinoid tumor has been reported, illustrating the unique complexity and heterogeneity of divergent histogenesis and cell differentiation in lung cancer. (wikipedia.org)
Approximately one-half of new cases each year are recorded in China, and the majority is squamous cell carcinoma ( 3 - 5 ). (spandidos-publications.com)
Majority are well differentiated and mimic proliferative endometrial glands and, as such, are referred to as endometrioid carcinoma. (slideserve.com)
Moreover, the most common type of tumor was complex carcinoma - 33.3% (5 cases). (biomedcentral.com)
Than histological score was correlated with tumor grade using the Gleason scoring system were the cancers were divided into well differentiated prostatic carcinoma (G1) (Gleason score 2-6), moderately differentiated carcinoma (G2) (Gleason score 7) and poorly differentiated carcinoma (G3) (Gleason score 8-10). (journalcra.com)
One third of patients with cancer of unknown primary origin have poorly or undifferentiated carcinoma. (medscape.com)
By a retrospective review of 595 consecutive radical gastrectomies for early gastric carcinoma from 2006 to 2018, we identified 8 (1.3%, 8/595) EBV-GCLS cases. (biomedcentral.com)
There are many types of HPV virus and most cases of squamous cell carcinoma are caused by the high-risk types HPV-16 and HPV-18. (mypathologyreport.ca)
What does it mean if squamous cell carcinoma of the vagina is described as well, moderately, or poorly differentiated? (mypathologyreport.ca)
Well differentiated squamous cell carcinoma of the vagina - A well differentiated tumour (grade 1) is made up of tumour cells that look almost the same as normal squamous cells. (mypathologyreport.ca)
Moderately differentiated squamous cell carcinoma of the vagina - A moderately differentiated tumour (grade 2) is made up of tumour cells that clearly look different from normal squamous cells, however, they can still be recognized as squamous cells. (mypathologyreport.ca)
Poorly differentiated squamous cell carcinoma of the vagina - A poorly differentiated tumour (grade 3) is made up of tumour cells that look very little like normal squamous cells. (mypathologyreport.ca)
Almost all cases of squamous cell carcinoma in the vagina are positive for p16. (mypathologyreport.ca)

In contrast, HPC2 1-B3 immunostained the cytoplasm and luminal surface of all 16 well- to moderately differentiated pancreatic ductal adenocarcinomas. (elsevierpure.com)
One series of 34 primary papillary adenocarcinomas reported that 20% were well differentiated, 68% were moderately differentiated, and 6% were poorly differentiated. (medscape.com)
Forty-one cases were used for our study, comprising 40 adenocarcinomas (six well differentiated, 26 moderately differentiated, and eight poorly differentiated) and one high-grade non-Hodgkin large cell lymphoma. (atpjournal.org)

The incidence of these tumours has increased by 54% during the past decade, reaching 0.97 cases per 100,000 population in the USA, probably indirectly related to the higher use of computed tomography (CT) scan that allows early diagnosis in asymptomatic patients [ 1 ]. (karger.com)
Of the 15 cases examined, 2(13.3%) had well-differentiated (grade I), 6(40%) had moderately differentiated (grade II) and 7(46.7%) had poorly differentiated (grade III) tumours. (biomedcentral.com)
The relationship between body size and prostate cancer risk, and in particular risk by tumour characteristics, is not clear because most studies have not differentiated between high-grade or advanced stage tumours, but rather have assessed risk with a combined category of aggressive disease. (biomedcentral.com)
The grade is important because higher-grade tumours (moderately and poorly differentiated tumours) behave in a more aggressive manner and are more likely to spread to other parts of the body. (mypathologyreport.ca)
A search constitutes 0.6%-5% of all human malig- was made for cases of oropharyngeal cancer nant tumours [ 5 ]. (who.int)

The latest meta-analysis published in a peer-reviewed journal classified incident prostate cases into two categories ('localised' or 'advanced') using a combination of Gleason score, World Health Organization (WHO) grading system, tumour node metastasis (TNM) stage, Jewett-Whitmore staging system and prostate-specific antigen (PSA) levels [ 13 ]. (biomedcentral.com)
The registers of oropharangeal cancer cases the area in the world with the highest inci- were reviewed to collect personal and clini- dence of oral cancer was Melanesia (31.5 cal data about the site, size, histopathologi- per 100 000 in men and 20.5 per 100 000 cal type, grading and staging of the tumour. (who.int)

In Italy, the main indications for neoadjuvant chemotherapy currently include the following: locally advanced BC , since in most cases these are not susceptible to conservative surgery and because of the higher risk of relapse early-stage BC if conservative surgery is not feasible, for example, due to a high tumorbreast ratio or if the expected cosmetic outcome is suboptimal due to the particular tumor location. (breastcancertalk.net)
Tumor size was 2 cm or smaller in 85% of the cases. (oncolink.org)
PET-CT scans were able to reveal an unknown primary tumor in 57% of cases compared with CT scan alone, which identified the unknown primary tumor in 23% of cases. (medscape.com)

The American Society of Clinical Oncology/College of American Pathologists consensus panel has published guidelines for cases when either IHC or ISH testing is equivocal. (breastcancertalk.net)

In many cases, ascertaining the true source of these neoplasms is difficult. (medscape.com)
As in the colon, these neoplasms range from well differentiated to moderately differentiated to poorly differentiated. (medscape.com)

50% of cases of bone metastasis involve multiple bony sites. (medscape.com)

The evaluation of squamous intraepithelial lesions (SILs) was performed in 21 cases. (scielo.br)
Even though most of the lesions were well differentiated and completely excised surgically, the differential diagnoses between cSCC and other skin malignancies were made based on the morphological aspects of the lesions, followed by an immunohistochemical profile when necessary. (actamedicamarisiensis.ro)

This result sustained when restricted to postmenopausal women and was stronger among metastatic BC cases (HR 3-unit 0.81, 95% CI: 0.72-0.91). (biomedcentral.com)
Consuming a Mediterranean diet before BC diagnosis may improve long-term prognosis, particularly after menopause and in cases of metastatic breast cancer. (biomedcentral.com)
10 ] reported a reduced incidence (25.5%) of grades 3 and 4 neutropenia and no cases of FN in a phase I/II trial of biweekly DCF (bDCF) regimen for metastatic esophageal cancer without a decrease in antitumor activity of the standard DCF therapy. (biomedcentral.com)

Results: Of the 96 cases included in the study, 82 were identified as cSCC, 5 as Bowen Disease, and 9 as keratoacanthoma. (actamedicamarisiensis.ro)

Overlapping lung and pleural involvement in individual cases has given rise to the more inclusive term "pleuropulmonary" synovial sarcoma. (medscape.com)

After Ang II treatment, poorly differentiated endometrial cancer cell line acquired a mesenchymal phenotype, which was characterized by induced expression of EMT-related genes (VIM, CD44, SNAI1, ZEB1 and ZEB2). (spandidos-publications.com)
Most endometrial cancer cases are diagnosed in the early stages and therefore result in favourable clinical outcomes ( 2 ). (spandidos-publications.com)

The latest World Cancer Research Fund meta-analysis reported that height was related to total prostate cancer and 'advanced' prostate cancer, including as 'advanced' prostate cancer various aggressive forms of the disease, but not differentiating between stage, grade and prostate cancer death because of the small number of available studies with data on these separate outcomes [ 12 ]. (biomedcentral.com)

The majority of low-grade to intermediate-grade IPMNs were positive (66% of cases). (elsevierpure.com)

Cytologic testing may not differentiate between a liposarcoma and a lipoma, so a surgical biopsy is recommended for diagnosis. (ivis.org)

Accordingly, immunohistochemistry with specific antibodies shows that HMGCS2 is expressed mainly in differentiated cells of human colonic epithelium. (aacrjournals.org)
We also showed that dose-dependent induction of proliferation was connected with changes in the expression of MKI67, CCND1 and CCNE1 genes in well- and poorly differentiated cancer cells. (spandidos-publications.com)

Case Rep Oncol (2020) 13 (1): 69-75. (karger.com)

We evaluated the prognostic value of this proposed grading system in a multicenter cohort of 311 cases of early OTSCC. (oulu.fi)

The demographic data, details of habit history, their duration of usage, and lymph node involvement of the cases were retrieved from the previous records. (thejcdp.com)
HPV positivity is an important factor in the lymphatic invasion, peripheral lymph node involvement, and histologic grade of cases with HNSCC and should be further investigated for its effect on prognosis. (iranpath.org)

Race-specific case proportions and incidence rates based on estrogen receptor (ER) status and histologic grade were estimated. (cdc.gov)

Totally, 33 cases were diagnosed as grade I OSCC, 27 cases as grade II OSCC, and 30 cases as grade III OSCC. (thejcdp.com)

We included 96 cases that were diagnosed between January 1, 2017, and December 31, 2020. (actamedicamarisiensis.ro)
Breast cancer (BC) is the most commonly diagnosed cancer and the fifth most common cause of cancer death worldwide, accounting for approximately one in four cancer cases and one in six cancer deaths in 2020 [ 1 , 2 ]. (biomedcentral.com)

The study material consisted of formalin-fixed, paraffin-embedded tissues of histologically diagnosed cases of OSCC retrieved from the Department of Oral and Maxillofacial Pathology, S.C.B Dental College & Hospital, Cuttack, Odisha, India. (thejcdp.com)

There is no consensus yet concerning the treatment in cases of recurrences or distant metastases. (trillium.de)

Positive controls of Ki-67 included histopathologically confirmed cases of ameloblastoma. (thejcdp.com)
Methods: A retrospective cross-sectional study was performed of histopathologically diagnosed cases of cSCC from the clinical Pathology Department of the Mures Clinical County Hospital, Târgu Mureș, Romania. (actamedicamarisiensis.ro)

Over 80% of MPM cases are associated with asbestos exposure, and therefore asbestos is the major factor implicated in MPM tumorigenesis (Broeckx and Pauwels, 2018). (atlasgeneticsoncology.org)
2018). However, these constitute a small percentage of cases. (atlasgeneticsoncology.org)

In the latter case, clearly specified quantitative benchmarks, such as median lethal doses (LD50s) for acute toxicity and no- observed-adverse-effect levels (NOAELs), or equivalent point of departure such as benchmark dose lower confidence limit (BMDL), for STOT-RE, are used. (cdc.gov)

The mechanism by which particulates cause disease remains poorly understood due to the lack of mechanistic insights into particle-biological interactions. (cdc.gov)
With the recent Zika virus outbreaks in the Americas, the number of Zika virus disease cases among travelers visiting or returning to the United States is increasing. (cdc.gov)

The surgical strategy should in these cases be combined with a neoadjuvant or adjuvant radio-/chemotherapy. (trillium.de)

Therefore, we collected EBV-GCLS cases and studied clinicopathology and prognosis. (biomedcentral.com)

We obtained a correct cytohistological correlation in 14/15 cases (93.3%) when all cytopathological examinations were considered. (biomedcentral.com)

Radical surgery in combination with multivisceral resection is the therapy of choice for highly to moderately differentiated liposarcomas. (trillium.de)
In these cases radical surgery cannot reduce the risk for local recurrence, therefore it is sufficient to perform a marginal resection. (trillium.de)
When liposarcomas recur, radical surgery only plays a role in cases where the recurrence is unifocal and the time interval between the first resection and the recurrence has been longer than one year. (trillium.de)

ABSTRACT The 5-year survival rate of female breast cancer cases in Jordan and some of the factors that affected survival were measured. (who.int)
RÉSUMÉ Le taux de survie à cinq ans chez les femmes atteintes d'un cancer du sein en Jordanie et certains des facteurs ayant eu une influence sur la survie ont été mesurés. (who.int)
Toutes les femmes jordaniennes chez lesquelles un nouveau diagnostic de cancer du sein avait été posé en 1997-1998 ont été incluses. (who.int)
Introduction Cervical cancer is the third most common malignancy among women worldwide, with an estimated global incidence of over 500,000 new cases and tremendously high death cases of 260,000 annually [1]. (kipdf.com)
A total of 13,270 incident breast cancer cases were identified from an initial sample of 318,686 women in 9 countries from the European Prospective Investigation into Cancer and Nutrition (EPIC) study. (biomedcentral.com)
Material and Methods: A retrospective study was conducted using 70 cases of diagnosed prostatic cancer from radical prostatectomy samples. (journalcra.com)
ABSTRACT A retrospective cohort study was conducted to determine the 5-year survival and prog- nostic factors for survival for 407 oropharyngeal cancer cases registered in the 3 main hospitals in Alexandria, Egypt, from 1996-2000. (who.int)
Lynch Syndrome Lynch syndrome is an autosomal dominant disorder responsible for 2 to 3% of cases of colorectal cancer ( 1). (msdmanuals.com)

This was a case-control study conducted from September 2014 to December 2015 at Sri Aurobindo Medical College and Postgraduate Institute, Indore, India. (gastrores.org)

However, a larger series of 12 cases revealed no p53 gene mutations. (wikipedia.org)

Although tobacco and alcohol consumption have been identified to increase the risk of HNSCC significantly ( 6 ), in 25% of HNSCC cases, such a relation cannot be found ( 7 ). (iranpath.org)

Level of evidence C2] The most common primary site was the appendix (36 of 45 cases). (oncolink.org)
Rarely, special immunostains and genomic next-generation sequencing will identify the primary site, and some of these cases may be curable if diagnosed promptly. (medscape.com)

Case reports suggest that chemotherapy with UFT may be useful in FA. (wikipedia.org)

HTLV-1 is the etiological agent of Adult T-cell Leukemia (ATL) and of HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP), whereas HTLV-2 does not cause hematological disorders and is only sporadically associated with cases of subacute myelopathy. (bvsalud.org)

HPC2 1-B3 was negative in all 31 cases of chronic pancreatitis that were tested. (elsevierpure.com)
Some cases are likely related to chronic inflammation (i.e. (basicmedicalkey.com)

RESULTS: Among 3279 case-participants and 3998 control-participants who had completed 2 mRNA doses, we estimated that the VE of a booster dose against COVID-19 declined from 86% (95% confidence interval, 81%-90%) during Delta predominance to 65% (58%-70%) during Omicron predominance. (cdc.gov)

Tumors14

Carcinomas4

Adenocarcinoma3

Carcinoma13

Adenocarcinomas3

Tumours5

Tumour2

Tumor3

Pathologists1

Neoplasms2

Metastasis1

Lesions2

Metastatic3

Keratoacanthoma1

Lung1

Endometrial2

Aggressive1

Majority1

Diagnosis1

Cells2

Oncol1

Prognostic1

Lymph node involvement2

Histologic1

Grade1

20202

OSCC1

Recurrences1

Histopathologically2

20182

Toxicity1

Disease2

Surgical1

Prognosis1

Correlation1

Resection3

Cancer8

Study1

Series1

Found1

Primary site2

Chemotherapy1

Cell1

Chronic2

Results1