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  • 2016
  • On July 25, 2016, the U.S. Department of Health & Human Services (DHHS) proposed a new bundling model as part of its mission to shift Medicare payments from quantity to quality. (scct.org)
  • SCCT's Advocacy Committee (consisting of several dedicated volunteers and expert staff) is preparing comments to DHHS on this proposed bundling model by the due date of September 26, 2016. (scct.org)
  • Methods
  • However, methods for assessment of cardiac safety of non-pharmaceutical agents are lagging behind the traditional health hazards of concern to human health (carcinogenicity, mutagenicity, reproductive toxicity, etc. (epa.gov)
  • Another important aspect was the development and application of different methods and techniques to various cardiovascular recordings in order to differentiate between diseased and healthy states. (hindawi.com)
  • ventricular
  • Left ventricular (LV) pressure-volume (P-V) analysis was used to assess cardiac performance. (biomedcentral.com)
  • In three latest human ventricular myocyte models, we examined the contribution of transmembrane currents to the shape of the electrical signal (i.e. on the action potential duration). (ox.ac.uk)
  • Finally, there is an interest to determine the potential antiarrhythmic effects of the green tea catechin Epigallocatechin-3-Gallate (E3G), by employing numerical simulations of cellular and cable models using atrial, Purkinje, and ventricular kinetics. (hindawi.com)
  • functional
  • Human induced pluripotent stem cells (hiPSCs) hold promise for myocardial repair following injury, but preclinical studies in large animal models are required to determine optimal cell preparation and delivery strategies to maximize functional benefits and to evaluate safety. (biomedsearch.com)
  • However, functional measurements of the right ventricle (RV) are also essential for fully understanding cardiac function. (biomedcentral.com)
  • In this review, we provide a summary of the current state-of-the-art bioengineering technologies used to create functional cardiac tissues for a variety of applications in vitro and in vivo. (springer.com)
  • To date, a variety of approaches have been used to bioengineer functional cardiac constructs, including biomaterial-based, cell-based, and hybrid (using cells and biomaterials) approaches. (springer.com)
  • Previous reports have documented diabetic cardiomyopathy is accompanied by cardiac structural and functional abnormalities. (nih.gov)
  • Mathematical
  • In this study, we use mathematical modeling and computer simulations to investigate EAD synchronization and arrhythmia induction in tissue models with random cell-to-cell variations. (biomedsearch.com)
  • assessment
  • 6. Upshaw J, Kiernan MS. Preoperative Cardiac Risk Assessment for Noncardiac Surgery. (tuftsmedicalcenter.org)
  • The long-term objective of the Center is to advance chemical risk assessment by establishing and validating effective, accurate and fiscally responsible means for identifying/characterizing cardiac chemical hazards. (epa.gov)
  • We next demonstrated the use of this method as an assessment tool for characterizing the structure of cardiac ionic models. (ox.ac.uk)
  • investigate
  • However, to a lesser extent, other models are also employed to investigate the cardiovascular adaptations. (medsci.org)
  • In this context, our group began to investigate the effects of RT on the cardiovascular system in rats. (medsci.org)
  • Some studies propose to investigate the level of temporal dependency in cardiovascular time series using a copula method. (hindawi.com)
  • The leptin receptor-deficient db/db mouse is a well-established type II diabetes animal model used to investigate diabetic cardiomyopathy. (nih.gov)
  • therapy
  • The goal is to identify the patient's condition and to predict the future patient-specific reaction, making this approach a potential means for model-based guided therapy. (canterbury.ac.nz)
  • compensatory
  • Experimental models that try to mimic these adaptations in rats, use a model of chronic muscle stretching, compensatory overload and electric stimulation in unconscious animals. (medsci.org)
  • aortic
  • Sun Z, Squelch A. Patient-specific 3D printed models of aortic aneurysm and aortic dissection. (springer.com)
  • Ho D, Squelch A, Sun Z. Modelling of aortic aneurysm and aortic dissection through 3D printing. (springer.com)
  • approach
  • Another approach is to use a 3D modeling for hemodynamic analysis of fluid structure interaction in intima and adventitia. (hindawi.com)
  • pathway
  • The newly developed tool has been validated using the model of IP3-calcineurin signal transduction pathway model which has 30 parameters. (ox.ac.uk)
  • heart
  • The SIMULIA Living Heart Human Model provides a unique testing environment where a stent can be deployed virtually in coronary arteries and deformed mechanically during the cardiac cycle. (drugdiscoveryonline.com)
  • A multi-state model to predict heart failure hospitalizations and all-cause mortality in outpatients with reduced ejection fraction: model derivation and external validation. (tuftsmedicalcenter.org)
  • Recent advances in the development of organotypic beating cardiomyocyte models (OCM), most notably derived from human/rodent embryonic or induced pluripotent (iPSC) stem cells, open new prospects for simulating complex chemical-perturbed adverse outcome pathways in the heart. (epa.gov)
  • Bio Alexander D. Kaiser is an applied mathematician who researches modeling and simulation of heart mechanics. (stanford.edu)
  • rats
  • 2 ] created a model that mimics squat-training (figure 1 ) performed by humans, for rats and today it is the most common model used by many laboratories. (medsci.org)
  • vitro
  • Project 3 will conduct dose-response modeling to establish appropriate point of departure, genome-wide association analyses and in vitro-to-in vivo extrapolation modeling. (epa.gov)
  • system
  • To provide more consistent care a cardiovascular system model is combined with an efficient patient-specific parameter identification method. (canterbury.ac.nz)
  • In the last 10 years the number of studies showing the benefits of resistance training (RT) to the cardiovascular system, have grown. (medsci.org)
  • Byrne N, Velasco FM, Tandon A, Valverde I, Hussain T. A systematic review of image segmentation methodology, used in the additive manufacture of patient-specific 3D printed models of the cardiovascular system. (springer.com)
  • variability
  • This project will develop and validate a population-based human and mouse cardiac organotypic culture model for characterizing susceptibility and variability in response to chemical hazards. (epa.gov)
  • analysis
  • To accelerate the solution time of the guide point modeling analysis, we added 192 computer-generated data points ("phantom points") whose initial positions are evenly distributed on the surfaces of the simplified model. (biomedcentral.com)
  • During the interactive guide point modeling analysis, the phantom points are updated based on global shape changes extrapolated from the guide points using a single-element trilinear FE model. (biomedcentral.com)
  • Analysis of errors in medical rapid prototyping models. (springer.com)
  • Patient
  • The only documented complication was a small pericardial effusion not requiring drainage in a patient that was prescribed conventional lead positioning by the model. (biomedcentral.com)