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  • neurons
  • Now, University of Missouri researchers Ashwin Mohan and Sandeep Pendyam, doctoral students in the Department of Electrical and Computer Engineering , are utilizing computational models to study how the brain's chemicals and synaptic mechanisms, or connections between neurons, react to cocaine addiction and what this could mean for future therapies. (missouri.edu)
  • mathematical
  • Polysaccharides are the topic of heightened curiosity this present day, and this publication is a concise and entirely up to date examine of the houses of nutrients polysaccharides, describing their interplay with water, the mass-volume-pressure-relationship, a variety of sorts of mathematical modeling, and the typical phenomenology lower than diversified combos of stimuli. (juridikinstitutet.se)
  • validity
  • Each of the chapters will address this issue, considering the utility, validity, generalizability, and limitations of the models presented. (springer.com)
  • 6 Environmental construct validity Environmental construct validity considers the effects of environmental factors known to confer increased risk for mental illness, and whether these factors are associated with the altered behavioral phenotype in the animal model. (juridikinstitutet.se)
  • neural
  • Systems for neural differentiation of hESCs and iPSCs have provided an experimental model that can be used to augment in vitro studies of in vivo brain development. (hindawi.com)
  • The constant activation of inflammatory and apoptotic pathways at low levels of exposure in human brain capillary endothelial cells, astrocytes, and neural progenitor cells may amplify devastation to neurological tissues and lead to neurological system cell damage from indirect events triggered by the presence of trichothecenes. (biomedsearch.com)
  • behavioral change
  • We think it self-e- dent, however, that humans can only be experimented upon in severely proscribed circumstances and alternative pro- dures using cell or tissue culture are inadequate in any models requiring assessments of behavioral change or of complex in vivo processes. (foyles.co.uk)
  • researchers
  • The researchers found that with TREX1 not functioning normally, all of the cell models displayed excess extra-chromosomal DNA and that a major source of the excess DNA came from LINE1 (L1) retroelements. (eurekalert.org)
  • studies
  • Thus, undifferentiated high-passage SH-SY5Y cells could be a good noradrenergic model for in vivo studies. (wichita.edu)
  • conditions
  • Another common model, MN9D cells, store high levels of DA under normal growth conditions, but do not convert it to NE. (wichita.edu)
  • potential
  • The models offer innovation potential by underpinning support systems for clinical and drug-development applications. (europa.eu)
  • systems
  • It then narrows to evaluate the use of a model systems approach to explore neurotoxin-induced leaming and memory deficits in animals as related to humans with dementia. (springer.com)
  • complex
  • When bicamerality as a method of social control was no longer adaptive in complex civilizations, this mental model was replaced by the conscious mode of thought which, Jaynes argued, is grounded in the acquisition of metaphorical language learned by exposure to narrative practice. (wikipedia.org)
  • present
  • Our model showed that the glutamate transporters, a protein present around these connections that remove glutamate, are almost 40 percent less functional after chronic cocaine usage," Mohan said. (missouri.edu)