Models musculoskeletal physiological phenomena. Medical search. Frequent questions

Rigid-body mechanics and musculoskeletal physiology are used to describe the dynamics of the segment model and muscle model. (elsevierpure.com)
Upper extremity strength can be predicted from musculoskeletal geometry and physiology using linear programming. (elsevierpure.com)
We also work on algorithms for simulations of various phenomena in physics and physiology. (lu.se)

The following bioengineering laboratories are currently housed at the Center: Musculoskeletal Research Center, MSRC, (Dr. Savio Woo), Cardiovascular Systems Laboratory (Dr. Sanjeev Shroff), Bioengineering Methods and Applications Laboratory and BioTransport Laboratory (Dr. Jack Patzer), Vascular Bioengineering Laboratory (Dr. David Vorp), Cell Migration Laboratory (Dr. Partha Roy), Computational Biomechanics Laboratory (Dr. Spandan Maiti) , Orthopaedic Robotics Laboratory (Drs. Volker Musahl and Richard Debski) and Molecular Biological and Biophysical Core Facilities (Department). (pitt.edu)
Comparative biomechanics is often applied in medicine (with regards to common model organisms such as mice and rats) as well as in biomimetics , which looks to nature for solutions to engineering problems. (wikipedia.org)
Department faculty members have teaching and research expertise in areas related to cardiovascular and fluid biomechanics, musculoskeletal biomechanics, biomaterials and tissue engineering, bioinstrumentation, biosystems, biomedical imaging, biological signal analysis, bioinformatics and computational biology, respiratory and pulmonary engineering, and other allied fields. (uiowa.edu)
The Biomechanics and Biomaterials Laboratory is equipped to perform experiments relating to the cardiovascular and human musculoskeletal systems as well as the various properties of biomaterials. (uiowa.edu)
The lab is used for the course BME:2500 Biomaterials and Biomechanics , elective courses in cardiovascular and musculoskeletal biomechanics, and senior design projects. (uiowa.edu)

Review of ergonomic issues encountered in engineering design, including biomechanical, physical and physiological issues. (carleton.ca)
A three-dimensional biomechanical model of the upper extremity was developed, and the predictions were compared to maximal arm strength data collected from healthy volunteers. (elsevierpure.com)
A static three-dimensional biomechanical model of the glenohumeral, radio-humeral, ulno-humeral and wrist joints was developed for predicting maximal hand exertion forces. (elsevierpure.com)

These studies were therefore never designed to form models of therapeutic manipulation, and the models formed were erroneous in that they described the target joint as being configured at the end range of a rotation movement, during the orientation phase. (wikipedia.org)

Modeling of neuromuscular biological signals, including subthreshold phenomena, active behaviour of cell membranes, and innervation processes. (carleton.ca)

The aim of the project was to accumulate the expertise for mathematical and computer modelling of ageing processes, including forecasting models for prevention and rehabilitation, and examining assistive technological solutions which could contribute to the improvement and enhancement of older people's quality of life, and assessment of the impact of factors, such as demography, mobility, health, lifestyle, and others to the ageing process. (europa.eu)
Under certain mathematical circumstances, blood flow can be modeled by the Navier-Stokes equations . (wikipedia.org)
Although several optimization-based mathematical models of the shoulder have been developed, none have utilized the mathematical properties of the Karush-Kuhn-Tucker multipliers to efficiently estimate the effect of strengthening individual muscles on functional strength of the whole arm. (elsevierpure.com)

The model describes yoga practice as a comprehensive skillset of synergistic process tools that facilitate bidirectional feedback and integration between high- and low-level brain networks, and afferent and re-afferent input from interoceptive processes (somatosensory, viscerosensory, chemosensory). (frontiersin.org)
Bringing conscious awareness to those physiological processes influences how we process those stimuli and can help us manage them more effectively. (breakingmuscle.com)

Viscoelasticity, mechanical properties and models of muscles, ligaments and tendons. (carleton.ca)
Interpretation of physical laws as applied to human motion, kinematics and dynamics of humanoid robots, modeling of biological sensors and actuators, artificial muscles, tele-manipulation, robot assisted surgery, and multi-fingered end-effectors. (carleton.ca)
The purpose of this study was to develop a computer model for identifying muscles critical to improving functional upper extremity strength. (elsevierpure.com)

Modeling of perfused tissues and cells. (carleton.ca)
In addition, NRF2 activation attenuated the dysfunction of NP cells induced by the dampened IVD clock and the degenerative process of NP tissues in an organotypic tissue-explant model. (biomedcentral.com)

Emerging research has revealed positive adaptations in response to overload stress in these people, including evidence for peripheral neuroplasticity in animal models and early clinical trials. (nih.gov)
This perspective article reviews the evidence for peripheral neuroplasticity in animal models and early clinical trials, as well as adaptations of the integumentary system and the musculoskeletal system in response to overload stress. (nih.gov)
The force a muscle produces is assumed to be proportional to its maximum stress, physiological cross-sectional area, activation, and its functional configurations including the muscle architecture, muscle length, contracting velocity, and passive tension. (elsevierpure.com)
Emotional stress can cause a very real physiological effect, but most of the time this is a subconscious process. (breakingmuscle.com)

This laboratory is under the direction of Jack Patzer, PhD and focuses on research related to the application of BioThemodynamics and BioTransport Phenomena (principles of heat, momentum, and mass transport) to understanding the properties of physiological systems, medical devices, and bioreactor engineering. (pitt.edu)
The modeling procedure relies entirely on established physiological principles. (elsevierpure.com)

Early models describing the kinematics of an individual target joint during the various phases of manipulation (notably Sandoz 1976) were based on studies that investigated joint cracking in MCP joints. (wikipedia.org)

Medical Instrumentation relates to physiological measurements for diagnostic, therapeutic, and monitoring applications. (carleton.ca)
Image-guided surgery and intervention, computational modeling for therapeutic applications, soft-tissue mechanics, biotransport, and inverse problems in therapeutics and imaging. (vanderbilt.edu)

Thus, the aim of this conceptual paper was to propose a complex system model for sports injuries and to demonstrate how the implementation of complex system thinking may allow us to better address the complex nature of the sports injuries aetiology. (bmj.com)
Yet, this conclusion is apparently true for vitamin D. Now, perhaps even more than nearly a century ago when the first investigational studies were conducted to elucidate the etiology of rickets [ 7 ], research has revealed that the beneficial effects of the vitamin D endocrine system may extend beyond the musculoskeletal system. (hindawi.com)
The HIQA Report on the investigation into the quality, safety and governance of the care provided by Tallaght Hospital for patients requiring acute admission has recommended that an Emergency Department-specific system of physiological monitoring and triggered responses comparable to the National Early Warning Score (NEWS) should be. (hrb.ie)
Sensations of the musculoskeletal system. (alento.nl)

Computational models and simulations are used to predict the relationship between parameters that are otherwise challenging to test experimentally, or used to design more relevant experiments reducing the time and costs of experiments. (wikipedia.org)
The Gaussian process regression (GPR) models of microstructure are shown to be just as good at interpolation as traditional CALPHAD models, with advantages in speed, retrainability, incorporation of non-equilibrium effects, and the effective inclusion of computational data. (cam.ac.uk)
While simulation of physical scenarios is to some degree accurate, it is inevitable that uncertainties will arise from simplifications made in computational models. (cam.ac.uk)

We will also consider and compare models of mechanical loading that use high-intensity muscular contractions to induce positive physiological responses in various populations, and suggest the applicability and modifications of these approaches when integrated into contemporary resistance training exercise prescriptions with the anticipation that they may be implemented in occupational, military, athletic, and general populations. (cdc.gov)

This principle extends way beyond a physical and emotional connection - our entire language is built on this phenomenon. (breakingmuscle.com)
Incorporating the results of the microstructure models leads to models of creep strength that meaningfully reveal underlying physical mechanisms of creep deformation. (cam.ac.uk)

3) Data mining models of post-stroke mortality and analysis of risk factors of stroke patients admitted to hospital within 24 hours of suffering a stroke. (europa.eu)
Despite large efforts to test analgesics in animal models, only a handful of new pain drugs have shown efficacy in patients. (iasp-pain.org)
Background: Patients with regional musculoskeletal pain (RMSKP) are at risk for work disability and instability and associated social and financial deprivation. (hrb.ie)
GJH is characterized by the excessive range of motion of several joints due to ligamentous laxity, and may be associated with chronic and recurrent musculoskeletal symptoms in patients without any visible rheumatologic pathology 9 . (bvsalud.org)

The combination of exercise training and sodium-glucose cotransporter-2 inhibition improves glucose tolerance and exercise capacity in a rodent model of type 2 diabetes. (umassmed.edu)

Participants in this session will get to build the model themselves to see how information from sensors (input) can determine what should be done (output) through simple lines of code. (nsta.org)

Circadian rhythm is a widespread phenomenon in the natural world [ 9 ]. (biomedcentral.com)
Bilu C, Einat H, Zimmet P, Vishnevskia-Dai V, Schwartz WJ, Kronfeld-Schor N. Beneficial effects of voluntary wheel running on activity rhythms, metabolic state, and affect in a diurnal model of circadian disruption. (umassmed.edu)

Candidate objective measures may be based on minimally invasive imaging technologies, electrophysiological recordings, integration of multiparametric imaging and electrophysiology approaches, or their integration with other markers (e.g. , immune factors, genomic markers, physiological factors) through multiscale modeling or machine learning analysis. (nih.gov)
We develop and implement magnetic resonance imaging (MRI) methods for evaluation and diagnosis of musculoskeletal disease. (lu.se)
Lund University is one of the 21 sites within the consortium named TRISTAN (Translational Imaging in Drug Safety Assessment), that perform preclinical models and apply imaging techniques such as MRI, CT and PET to assess lesions in the lung tissue caused by drug administration. (lu.se)

The decline in functional capacity is a heterogeneous phenomenon in the elderly. (mdpi.com)

Overt skeletal muscle injury can occur following exposure to high-intensity muscular contractions implemented during mechanical loading, and this phenomenon is exacerbated with age. (cdc.gov)
In spite of this, current evidence supports a model of muscle adaptation following mechanical loading, distinct from overt injury, in which myofiber degeneration and inflammation does not contribute as significantly as once reported even following muscular contractions incorporating repetitive eccentric contractions. (cdc.gov)

In cancer treatment this phenomenon can be exploited to selectively kill tumour cells that have specific genetic mutations. (hrb.ie)
Autism has been modeled as a brain-based, strongly genetic disorder, but emerging findings and hypotheses support a broader model of the condition as genetically influenced and systemic. (autismbiology.com)

Here we provide a theoretical framework and systems-based network model of yoga that focuses on integration of top-down and bottom-up forms of self-regulation. (frontiersin.org)

We identified 204 studies (531 experiments) assessing the efficacy of pregabalin in behavioral models of pain. (iasp-pain.org)
Experiments did not generally report using design elements aimed at reducing threats to validity, and analgesic activity was typically tested in a small number of model systems. (iasp-pain.org)

However, after re-examining the original studies on which the kinematic models of joint manipulation were based, Evans and Breen argued that the optimal prethrust position is actually the equivalent of the neutral zone of the individual joint, which is the motion region of the joint where the passive osteoligamentous stability mechanisms exert little or no influence. (wikipedia.org)
This new model predicted that the physiologic barrier is only confronted when the articular surfaces of the joint are separated (gapped, rather than the rolling or sliding that usually occurs during physiological motion), and that it is more mechanically efficient to do this when the joint is near to its neutral configuration. (wikipedia.org)
This sound is believed to be the result of a phenomenon known as cavitation occurring within the synovial fluid of the joint. (wikipedia.org)

A physiological model for predicting muscle forces is described. (elsevierpure.com)
A model defining the force-length-velocity-activation relationship of a muscle is adopted. (elsevierpure.com)
Bird 11 considers that GJH depends not only on ligament laxity, but also on skin, blood vessels and adjacent muscle tissue that allow the occurrence of this phenomenon. (bvsalud.org)

Engineering analysis and modeling techniques applied to human motion. (carleton.ca)
Together with the Walter Reed Army Institute of Research, we are developing individual-specific phenomenological models to predict the effects of total sleep deprivation and chronic sleep restriction on human alertness and performance. (bhsai.org)

We have recently reported that chronic pain is associated with amplified activity of PB neurons in a rat model of neuropathic pain. (iasp-pain.org)
Our primary objective was to describe design characteristics and outcomes of studies testing the efficacy of pregabalin in behavioral models of pain. (iasp-pain.org)

BMAL1 is a core clock transcription factor, which promotes the transcription of downstream clock-controlled genes (CCGs) by targeting the E-box structure in their promoter region to regulate the physiological functions of the body. (biomedcentral.com)

To support our proposed model, we present the available evidence for yoga affecting self-regulatory pathways, integrating existing constructs from behavior theory and cognitive neuroscience with emerging yoga and meditation research. (frontiersin.org)
Each modality represents an approach to treatment of the musculoskeletal and other systems sought by a steadily increasing number of people, despite a relative dearth of quality, evidence-based research supporting their isolated use. (medscape.com)

Sports injuries aetiology investigations have assumed a reductionist view in which a phenomenon has been simplified into units and analysed as the sum of its basic parts and causality has been seen in a linear and unidirectional way. (bmj.com)

In order to accelerate the further development of these alloys, this thesis develops machine learning models that can better predict their microstructure and strength. (cam.ac.uk)

Univariate models were used to verify the risk of illness and the effects in terms of recurrence. (bvsalud.org)

This projects gives them the tools to help solve such a problem by building a model and finding a solution. (nsta.org)

Baclofen-loaded microspheres: preparation and efficacy testing in a new rabbit model. (uchicago.edu)

According to this approach, the phenomenon (injury) has been reduced into units and explained by rational deduction. (bmj.com)

Real-time individualization of the unified model of performance. (bhsai.org)

Assessment of the unified model of performance: accuracy of group-average and individualised alertness predictions. (bhsai.org)

Anatomy1

Diseases4

Analytical, Diagnostic and Therapeutic Techniques and Equipment1

Psychiatry and Psychology2

Phenomena and Processes18

Anthropology, Education, Sociology and Social Phenomena1

Technology, Industry, Agriculture1

Humanities1

Information Science2

Physiology3

Biomechanics5

Biomechanical3

Movement1

Neuromuscular1

Mathematical3

Processes2

Muscles3

Tissues2

Stress4

Principles2

Kinematics1

Therapeutic2

System4

Computational3

Responses1

Physical2

Patients4

Exercise1

Sensors1

Circadian2

Imaging3

Functional1

Overt2

Genetic2

Theoretical1

Experiments2

Joint3

Muscle3

Human2

Pain2

Body1

Research2

Investigations1

Predict1

Risk1

Projects1

Efficacy1

Approach1

Time1

Assessment1