Models for cardiovascular research research models cardiovascular. Medical search. Frequent questions

Cardiovascular diseases constitute a global health care crisis in which eHealth can provide novel solutions to improve the efficiency and reach of self-management support for patients where they most need it: their homes and communities. (utwente.nl)
Objective: The primary objective of this review is to facilitate a holistic interpretation of eHealth projects aimed at providing self-management support of cardiovascular diseases in the natural setting of patients, thus priming the use of remote monitoring technologies. (utwente.nl)
Conclusions: This review is important because it aims to create a holistic understanding of a multidisciplinary topic at the crossroads of eHealth, cardiovascular diseases, and self-management. (utwente.nl)
Our results will show how useful this method can be in bridging the multidisciplinary gap of eHealth research and development, to inform and advance the importance of holistic approaches, while showcasing this approach for the case of self-management in cardiovascular diseases. (utwente.nl)
Cardiovascular diseases cause a high mortality rate worldwide and represent a major burden for health care systems. (springer.com)
Experimental rodent models play a central role in cardiovascular disease research by effectively simulating human cardiovascular diseases. (springer.com)
Cardiovascular disease (CVD) is a world-leading health problem and encompasses a broad spectrum of disorders, including diseases of the blood vessels, the heart muscle, the electrical conduction system, and congenital heart disease. (springer.com)
Please specify that you would like your article to be considered for the 'Digital Technologies for Cardiovascular Diseases' article collection in your cover letter. (biomedcentral.com)
Compared to the general population, individuals with depression have an increased risk for cardiovascular diseases. (frontiersin.org)
Projections assume that depression will be the leading cause of disability worldwide by 2030 ( 9 ), which might be partly due to the high comorbidity with cardiovascular diseases (CVDs) ( 10 , 11 ). (frontiersin.org)
Fellows can choose their own research theses with reference to variety of research topics listed below, and are expected to obtain competence in basic and clinical knowledge in the field of cardiovascular diseases. (juntendo.ac.jp)
Physical activity is essential for preventing and controlling risk factors and chronic diseases, such as diabetes, high blood pressure (HBP), cardiovascular disease (CVD), obesity, cancer, and depression (1). (cdc.gov)
However, because good job data is lacking in major U. S. cardiovascular data bases, in order to test for comparable U.S. associations, we are obliged to develop a methodology for linking the data bases concerning job conditions and CHD incidence, respectively (a methodology which also can be applied to occupational diseases other than heart disease). (cdc.gov)
Intermittent fasting in rodents has been shown to reduce or prevent cellular dysfunction and degeneration in age-related neurological and cardiovascular diseases. (edu.au)
There is an elevated risk for development of atherosclerosis/cardiovascular (CV) diseases among first responders (FR) who were present at Ground Zero over the first 72 hr. (cdc.gov)
Aims We aim to estimate the cost and cost-effectiveness of population-based tobacco control strategies in the prevention of cardiovascular diseases (CVD) in Tanzania. (who.int)
The influence of social and behavioral factors in the workplace, or more accurately the composite elements of working life on cardio-vascular and other chronic diseases, has influenced several major currents in occupational health research. (cdc.gov)
BACKGROUND: Epidemiological studies have linked transportation noise and cardiovascular diseases, however, atrial fibrillation (AF) has received limited attention. (lu.se)

4 DZHK (German Centre for Cardiovascular Research), Berlin, Germany. (jci.org)
Collaborating researchers from the Centre for Cardiovascular Science and the University of Glasgow's School of Physics and Astronomy hope that by providing incredibly detailed time-lapse videos of growing zebrafish hearts, we can better understand the cellular and subcellular processes by which these hearts form and repair themselves. (ed.ac.uk)
Funding for the single plane illumination microscope (SPIM) and advanced transgenic zebrafish used in these studies was provided by The BHF Centre of Research Excellence Award, University of Edinburgh. (ed.ac.uk)

Li et al, Development 2019) as well as the developing cardiac conduction system at embryonic day 16.5 of mouse development (Goodyer et al, Circulation Research 2019). (stanford.edu)
Global Cardiovascular information system (CVIS) market is expected to grow in coming years owing to the increasing incidence rate of cardiovascular disorders thereby pushing the need for streamlining the cardiac care workflow systems. (prnewswire.com)
Cardiovascular information system aims to approve an advanced level of evidence-based proficient standards in cardiac recovery. (prnewswire.com)
In this review, we summarize the current advances of the IMPC in cardiac research and describe in detail the diagnostic requirements of high-throughput electrocardiography and transthoracic echocardiography capable of detecting cardiac arrhythmias and cardiomyopathies in mice. (springer.com)
A new proteomic risk model for cardiovascular disease was found to be more accurate than current methods of measuring cardiac risk, according to a new study led by researchers in the Perelman School of Medicine at the University of Pennsylvania. (news-medical.net)
Not only did the study indicate this model was more accurate compared to current approaches, the researchers were able to identify several proteins, like cartilage intermediate layer protein 2 (CILP2), that can be used in future research to identify cardiac risk or be the target for novel therapies. (news-medical.net)
The integration of in vitro cardiac tissue models, human induced pluripotent stem cells (hiPSCs) and genome-editing tools allows for the enhanced interrogation of physiological phenotypes and recapitulation of disease pathologies. (nature.com)
In vitro cardiac tissue models: current status and future prospects. (nature.com)
Advancing functional engineered cardiac tissues toward a preclinical model of human myocardium. (nature.com)
We invite original research and review articles focusing on interaction of cardiac inflammation, oxidative stress, and hypoxia in the setting of sepsis. (hindawi.com)
In this work, we test the hypothesis that in a statistical shape model (SSM), the modes that are most relevant for describing anatomy are also most important for determining the output of cardiac electromechanics simulations. (plos.org)
As a result, in cardiac models, representing patient anatomy using a limited number of modes of anatomical variation can cause a loss in accuracy of simulated electromechanical function. (plos.org)
This highlights the need to have high fidelity anatomical models in cardiac simulations and demonstrates that subtle changes in cardiac anatomy can have a large impact on cardiac function. (plos.org)
Ongoing studies extend from the bench and preclinical models to the clinics, wards and invasive cardiac catheterization laboratory. (mayo.edu)
In the realm of cardiac replacement therapy, Cardiovascular Research Center investigators have advanced the field through better understanding of the impact of ventricular assist devices and novel approaches to immunosuppression in patients undergoing cardiac transplantation. (mayo.edu)
Zebrafish hearts are commonly used in cardiac research as models for the human heart. (ed.ac.uk)
Specifically, the research focuses on understanding the mechanisms of various cancer therapies that induce cardiac toxicities. (hopkinsmedicine.org)

Mascheroni, P., Penta, R., Merodio, J. (2023) The impact of vascular volume fraction and compressibility of the interstitial matrix on vascularised poroelastic tissues Biomechanics and Modeling in Mechanobiology, 22, pp. 1901-1917. (gla.ac.uk)
Miller, L., Penta, R. (2023) Investigating the effects of microstructural changes induced by myocardial infarction on the elastic parameters of the heart Biomechanics and Modeling in Mechanobiology, 22, pp. 1019-1033. (gla.ac.uk)
2023). Proteomic cardiovascular risk assessment in chronic kidney disease. (news-medical.net)
Cite this: Model Helps Optimize Who Should Be Screened for Cancer - Medscape - Nov 08, 2023. (medscape.com)

Article of the Year Award: Impactful research contributions of 2022, as selected by our Chief Editors. (hindawi.com)

In the Cardiorenal Research Laboratory, Mayo Clinic researchers are developing unique biomarkers and testing novel peptide-based and gene-therapy-based strategies to better treat patients with heart failure and to prevent heart failure in patients at risk. (mayo.edu)
3. Identify novel biomarkers for food and nutrient intake related to dietary patterns and cardiovascular health. (usda.gov)
Researchers from France are developing a model to find biomarkers and clinical risk factors that can better identify individuals at risk for cancer who should be screened. (medscape.com)
Using machine learning, the team highlighted more than 30 biomarkers and 2 clinical risk factors among patients with cardiovascular disease who smoked and 13 biomarkers and 8 clinical risk factors among patients with Li-Fraumeni syndrome that could effectively identify those at risk for cancer. (medscape.com)
Using machine learning, the researchers found 33 biomarkers and 2 clinical risk factors among patients with cardiovascular disease that led to a cancer risk estimate with an area under the curve (AUC) of 0.78. (medscape.com)

The model discusses in detail the impact of COVID-19 on Coronary Stents market for the year 2020 and beyond. (marketresearch.com)
FELTON, California , April 28, 2020 /PRNewswire/ -- The global cardiovascular information system (CVIS) market was valued at USD 616.7 million in 2015 and is anticipated to reach USD 1.2 billion by 2024. (prnewswire.com)
CR and MM have received funding from the European Union's Horizon 2020 Research and innovation programme under the Marie Sklodowska-Curie Grant Agreement No 764738. (plos.org)
Future burden of cardiovascular disease in Australia: impact on health and economic outcomes between 2020 and 2029. (monash.edu)

8, 2019 People under age 40 diagnosed with type 2 diabetes are more likely to have or die from cardiovascular disease than people of a similar age who do not have type 2 diabetes. (sciencedaily.com)
La información más reciente sobre el nuevo Coronavirus de 2019, incluidas las clínicas de vacunación para niños de 6 meses en adelante. (stanfordchildrens.org)

We also offer postgraduate opportunities through our Honours, Masters and PhD programs, in areas spanning fundamental science using preclinical models, clinical studies, epidemiological and public health studies. (edu.au)
c cancer immunotherapy research program on a neoadjuvant therapy platform as well as a number of preclinical models of pancreatic cancer for developing innovative immunotherapy strategies. (hopkinsmedicine.org)

This new model was found to be more accurate in identifying those at risk of future cardiovascular disease, as compared to both the 2013 ACC/AHA Pooled Cohort Equation (PCE)-;which provides a set of guidelines for best practices in measuring cardiovascular risk-;and a modified PCE that included estimated glomerular filtrate rate (eGFR). (news-medical.net)

Our mission is to improve the lives of children with heart disease through patient centered research with demonstrable clinical outcomes. (ucl.ac.uk)
As the most forward-thinking heart and vascular program in the state, Georgia Heart Institute is actively conducting cutting-edge research focused on improving patient outcomes across the spectrum of specialties within cardiology. (nghs.com)
Thus, an RNAi therapeutic targeting Agt ameliorated the clinical sequelae and improved fetal outcomes in 2 rodent models of preeclampsia. (jci.org)
Our students work alongside researchers, in scientific laboratories or research units that are closely connected with clinical facilities and focus on the translation of findings into improved health outcomes. (edu.au)
The CNL will determine the relationship between food preferences, consumption patterns and dietary acculturation, and cardiovascular health using population-based datasets by assessing the impact of acculturation status on dietary patterns and health outcomes. (usda.gov)

1.3 - Synergistic effects of a 'heart healthy' diet and statin therapy on atherosclerosis using a porcine model. (usda.gov)

Methods: We will use Noblit and Hare's metaethnography approach to review and synthesize researchers' and practitioners' reports on how they applied frameworks, models, and theories in their projects. (utwente.nl)
We publish over 1,500 new titles per year by leading researchers each year, and have a network of expert authors, editors and advisors spanning the global academic community in pursuit of advanced research developments. (novapublishers.com)
The Penn researchers developed a model using proteomics, the large scale study of proteins. (news-medical.net)
Of those thousands of proteins evaluated, researchers used machine learning methods to choose 32 proteins that comprised their proteomic risk model. (news-medical.net)
The software and repository are used to simulate cardiovascular and pulmonary solid and fluid mechanics and to provide spatially and temporally resolved benchmark solutions that are used by academic, government, and industry researchers to verify their computational methods. (stanfordchildrens.org)
The Baker Department of Cardiovascular Research, Translation and Implementation brings together world class researchers from La Trobe University and the Baker Heart and Diabetes Institute. (edu.au)
Our researchers are experts in cardiovascular disease, diabetes and public health research. (edu.au)

This study sought to evaluate the relationship between subclinical hypothyroidism (SCH) and all-cause and cardiovascular disease (CVD) mortality. (nih.gov)
2009). Collectively, these changes increase the risk of cardiovascular disease, metabolic disease, obesity, insulin resistance, back pain, fall risk and all-cause mortality, and reduce the ability to perform activities of daily living and maintain overall independence. (acefitness.org)
Association of Spicy Chilli Food Consumption With Cardiovascular and All-Cause Mortality: A Meta-Analysis of Prospective Cohort Studies. (monash.edu)

This dataset is then used to train a convolutional neural network to classify images for cardiovascular abnormalities. (ibm.com)

Background: Electronic health (eHealth) is a multidisciplinary and rapidly evolving field, and thus requires research focused on knowledge accumulation, curation, and translation. (utwente.nl)
This research was funded by the Juvenile Diabetes Research Foundation and the Canadian Institutes of Health Research. (sciencedaily.com)
His scientific background includes pharmaco-epidemiology and big data research within nationwide Danish Health databases. (biomedcentral.com)
Georgia Heart Institute is one of very few health systems in the state to have received national funding through the National Institutes of Health (NIH) to perform research studies. (nghs.com)
Lifestyle interventions targeting healthy diet and/or physical activity are recommended as a physically active and healthy lifestyle contributes equally to patients' mental well-being and cardiovascular health. (frontiersin.org)
At Stanford Children's Health , we've been performing research related to CCTGA for nearly two decades. (stanfordchildrens.org)
In this article, Bayesian extensions of the classical Tobit model are used to study the relationship between health status and predictors of health. (ices.on.ca)
Models where the conditional distribution of health status was either normal or lognormal, and allowed for both homoscedasticity and heteroscedasticity were examined. (ices.on.ca)
There was very strong evidence that the distribution of the Health Utilities Index, conditional on age, gender, income adequacy, and number of chronic conditions, was normal with nonuniform variance, compared to the competing models. (ices.on.ca)
We have also conducted a wide spectrum of basic and clinical research to address this public health problem. (juntendo.ac.jp)
It broadens access to health services and research networks and enhances interdisciplinary research collaboration. (edu.au)
The Baker Department of Cardiovascular Research, Translation and Implementation provides a unique opportunity to build a collaborative base that strengthens our science, and accelerates translation of our research to improve the health and wellbeing of the communities we serve. (edu.au)
These guidelines are based on a synthesis of research, theory, and current practice and are consistent with the principles of the national health education standards (29), the opportunity-to-learn standards for health education (29), the position papers of leading voluntary organizations involved in child nutrition (30), and the national action plan to improve the American diet (31). (cdc.gov)
2. Determine the relationship between food preferences, consumption patterns and dietary acculturation, and cardiovascular health using population-based datasets. (usda.gov)
The Rotterdam study also used other methodology to assess lifestyle and/or health measures including the European cardiovascular disease risk assessment model. (cdc.gov)
Why is cardiovascular disease a problematic issue for many occupational safety and health investigators? (cdc.gov)
We found marginal improvement in influenza vaccination during the past hold income less than $50,000, and no health insurance had a decade among adults with cardiovascular disease, lagging far behind the lower prevalence of vaccination. (cdc.gov)

Cox proportional hazards models in the derivation cohort to derive risk equations accounting for competing risks. (bmj.com)
Analyses were conducted using Cox proportional hazards models with adjustment for individual and area-level sociodemographic covariates and long-term. (lu.se)

Each of the covered 39 country's color-coded and fully-sourced market models are equipped with epidemiology based indications with procedure volumes. (marketresearch.com)
Clinical research involves clinical epidemiology and clinical studies that occurs in clinical laboratory, and clinical trials. (juntendo.ac.jp)

Animal models have many facets that mimic various disease conditions in humans representing the importance for its tremendous use in biomedical research (Mukherjee et al. (springer.com)

Those specific proteins were determined to best help indicate a patient's risk level of heart attack, heart failure, stroke, or even cardiovascular death in those with CKD. (news-medical.net)

His experience includes 24 years of clinical practice, 19 years of translational research in nanomedicine, and 13 years of bench-to-bedside studies, including imaging, vascular pathology, and medical devices (bioresorbable scaffolds and stents). (biomedcentral.com)

Mathematical Biology is the application of mathematical modelling to solve problems in biology and physiology. (gla.ac.uk)
PhysioNet is a repository of freely-available medical research data, managed by the MIT Laboratory for Computational Physiology. (physionet.org)

IMPORTANCE: The US Preventive Services Task Force (USPSTF) is updating its 2016 recommendation on the use of aspirin for the primary prevention of cardiovascular disease (CVD) and colorectal cancer (CRC). (healthpartners.com)
OBJECTIVE: To provide updated model-based estimates of the net balance in benefits and harms from routine use of low-dose aspirin for primary prevention. (healthpartners.com)
Thus, for the average US man, CVD prevention should take precedence over prostate cancer prevention, based on probability and cumulative research. (medscape.com)
Our goal is to better understand who is at risk of cardiovascular and cardiometabolic disease, to identify the molecular pathways underpinning that risk, and to use this information to develop strategies for prevention and treatment. (edu.au)
The aim of this research is to optimize and individualize cancer screening and improve cancer prediction, detection, and prevention, according to Marine Fidelle, PharmD, PhD, research pharmacist at the Gustave Roussy Institute, Paris, who presented the findings at the Society for Immunotherapy of Cancer's (SITC) annual meeting in San Diego. (medscape.com)
Conclusions Even though all five interventions are deemed very cost-effective in the prevention of CVD in Tanzania, more research on budget impact analysis is required to further assess the government's ability to implement these interventions. (who.int)

The cutting-edge technology, expert research team and innovative capabilities of the Georgia Center for Cardiovascular Biomechanics & Data Modeling make it one of the leading programs in the nation. (nghs.com)

We subsequently conducted a systematic review of the handling and reporting of treatment use in prognostic model studies in cardiovascular medicine. (biomedcentral.com)
Especially for manuscripts describing randomized trials, qualitative research, and systematic review methods the Equator Network reporting guidelines should be followed. (biomedcentral.com)

We evaluated whether siRNA targeting maternal hepatic angiotensinogen (Agt) could ameliorate symptoms of preeclampsia without adverse placental or fetal effects in 2 rodent models. (jci.org)
ular toxicities in vitro, in cardiomyocyte culture and in vivo using rodent models. (hopkinsmedicine.org)
These rodent model studies - using relevant exposure scenarios mimicking mouth-breathing exposures/pollutant levels in that critical period - will help us better understand the bases for the still-increasing incidence of CV anomalies reported in first responders. (cdc.gov)

Hence, with this call for papers, BMC Cardiovascular Disorders acknowledges that new approaches are fundamental to the advancement of modern cardiology. (biomedcentral.com)
Please ensure your manuscript adheres to the submission guidelines for BMC Cardiovascular Disorders . (biomedcentral.com)

By participating in clinical trials and research, our team has access to an international community of heart and vascular clinicians with whom we can collaborate to ensure that we're using the latest techniques and most recent discoveries to improve patient care. (nghs.com)
This complex binds proteins to determine the fate of neurons, and we are studying the function of its various components in models of stroke, vascular dementia and ageing. (edu.au)
He is the medical director of vascular surgery unite at Örebro University Hospital and of the EVTM's (EndoVascular Resuscitation and Trauma Management) research group. (oru.se)
This entails extensive clinical and research practice within vascular surgery, surgery, intensive care and trauma. (oru.se)

The vision of the British Heart Foundation to enable such innovative collaborations will continue to transform our understanding of the cardiovascular system. (ed.ac.uk)
The two predominant models - demand-control and effort-reward imbalance - have supported internationally accepted survey instruments, inspire cross-disciplinary conceptual platforms and collaborations, and have footings in self-efficacy and social justice theory. (cdc.gov)

Coronary Stents (Cardiovascular) - Global Market Analysis and Forecast Model (COVID-19 Market Impact) is built to visualize quantitative market trends within Cardiovascular Devices therapeutic area. (marketresearch.com)
In an era of personalized medicine, these findings indicate a new route for future research into therapeutic targets. (news-medical.net)
Our scientists are designing new diagnostic, preventative and therapeutic strategies to tackle cardiovascular disease, diabetes and its complications. (edu.au)

Mice with pulmonary arterial hypertension had very high levels of Nogo in their lung arteries, but animal models that were genetically lacking Nogo were completely resistant to developing the disease," said Michelakis. (wun.ac.uk)
In addition to work done in laboratory models, the research team found that the level of Nogo was also high in arteries of patients with pulmonary arterial hypertension. (wun.ac.uk)

His research overlaps with these clinical areas but also covers broad aspects of medicine and innovation. (biomedcentral.com)
The study received funding from the European Union's Horizon Europe research and innovation program. (medscape.com)

Determine the effect of diets differing in fat and carbohydrate type on cardiometabolic risk indicators, lipoprotein and fatty acid metabolism, response to lipid modifying therapy, and gene-nutrient interactions, using human, animal and in vitro models. (usda.gov)
LAB NAME: Cardiovascular Nutrition In the next 5 years the Cardiovascular Nutrition Laboratory (CNL) will investigate the effects of diets differing in fat type and carbohydrate type on cardiometabolic risk factors, fatty acid metabolism, response to lipid modifying therapy, and gene-nutrient interactions using human, animal and in vitro models. (usda.gov)

Scientists at the Ottawa Hospital Research Institute and the University of Ottawa have discovered what may be an important clue to the cause of type 1 diabetes. (sciencedaily.com)
Dr. Scott's research is the first to clearly show that immune cells called T cells from people with type 1 diabetes are also more likely to over-react to wheat. (sciencedaily.com)
His research also shows that the over-reaction is linked to genes associated with type 1 diabetes. (sciencedaily.com)
Our research suggests that people with certain genes may be more likely to develop an over-reaction to wheat and possibly other foods in the gut and this may tip the balance with the immune system and make the body more likely to develop other immune problems, such as type 1 diabetes. (sciencedaily.com)
Dr. Scott's previous research has shown that a wheat-free diet can reduce the risk of developing diabetes in animal models, but he notes that more research will be required to confirm the link and determine possible effects of diet changes in humans. (sciencedaily.com)
Chronic kidney disease (CKD) is a strong cardiovascular risk factor and is often accompanied by hypertension and diabetes. (news-medical.net)
Our unique partnership harnesses the research strengths, resources and facilities of both organisations to optimise the scope, volume and quality of cardiovascular, diabetes and related research . (edu.au)

We welcome the submission of research papers (including methods), study protocols, technical advancements, systematic reviews, and meta-analyses. (biomedcentral.com)
The Marsden Lab at Stanford Engineering develops fundamental computational methods for the study of cardiovascular disease progression, surgical methods, treatment planning, and medical devices. (stanfordchildrens.org)
The research team in the Circulatory Failure Program uses gold standard invasive hemodynamic methods to better understand disease mechanisms and treatments in the human catheterization laboratory. (mayo.edu)
Tal Hörer's research is mainly focused on endovascular and hybrid surgical procedures for bleeding control, on resuscitation, on haemodynamic instability, as well as on advanced endovascular methods. (oru.se)
Materials and methods A cost-effectiveness analysis was performed using an Excel-based Markov model, from a governmental perspective. (who.int)

Because CPH-NEW is sponsoring a cardiovascular disease and stroke education and outreach population and is undertaking an intervention among Corrections Officers, a group with many stress related concerns, the issues around workplace interventions and CVD are cogent. (cdc.gov)

From innovative research and leading publications to specialized clinical trials, our physicians, surgeons and research team are directly involved in finding new and better ways to prevent and treat heart disease. (nghs.com)

In practice, however, such prognostic models are often derived from or validated in data sets where a proportion of the individuals has received that specific treatment. (biomedcentral.com)
He is leading various project on tools for bleeding management and resuscitation, as well as heading up research and clinical practice on aortic balloon occlusion (REBOA). (oru.se)
These guidelines are based on a review of research, theory, and current practice, and they were developed by CDC in collaboration with experts from universities and from national, federal, and voluntary agencies. (cdc.gov)

We conclude with suggestions for the handling and reporting of treatment use in prognostic model research. (biomedcentral.com)

The model of job -related CHD risk has been successfully tested in Sweden with incidence data at the individual level. (cdc.gov)
Influenza vaccination can reduce the incidence of cardiovascular ally during the past decade but is far behind the targeted national disease (CVD) in the US. (cdc.gov)

They are having preliminary success in their laboratory models. (wun.ac.uk)

CD133 + stem cells represent a promising subpopulation for innovative cell-based therapies in cardiovascular regeneration. (biomedcentral.com)

The Cardiovascular Research Institute at Baylor College of Medicine conducts a seminar series that is archived for interested faculty and students. (bcm.edu)
A multidisciplinary research team in the Faculty of Medicine & Dentistry at the University of Alberta has taken a big step towards understanding the cause and potential cure for a deadly cardiovascular disease. (wun.ac.uk)

The review aims to synthesize the operationalization of frameworks, models, and theories applied to the research and development process of eHealth. (utwente.nl)
Using mice, the International Mouse Phenotyping Consortium (IMPC) aims to target each protein-coding gene and phenotype multiple organ systems in single-gene knockout models by a global network of mouse clinics. (springer.com)
Graduate school of our department aims for researches which are based on clinical hypothesis and significance. (juntendo.ac.jp)

The Stanford BASE program brings together experts from multiple specialties across the Stanford University campus and its hospitals-including computational modeling, tissue engineering, genetics, and molecular biology-to create bold new solutions for children with heart disease. (stanfordchildrens.org)

The Department of Cardiovascular Biology and Medicine, Juntendo University has actively treated patients with wide variety of cardiovascular disease. (juntendo.ac.jp)

Seventy-nine articles (26%) excluded treated individuals from their analysis, 80 articles (26%) modelled treatment as an outcome, and of the 155 articles that developed a model, 86 (55%) modelled treatment use, almost exclusively at baseline, as a predictor. (biomedcentral.com)
All participants had CKD and no history of cardiovascular disease at study baseline. (news-medical.net)
After this baseline testing was complete, participants completed an individualized eight-week exercise program created by the research team following the ACE Integrated Fitness Training ® (ACE IFT ® ) Model. (acefitness.org)

The immune system has to find the perfect balance to defend the body against foreign invaders without hurting itself or over-reacting to the environment and this can be particularly challenging in the gut, where there is an abundance of food and bacteria," said Dr. Scott, a Senior Scientist at the Ottawa Hospital Research Institute and Professor of Medicine at the University of Ottawa. (sciencedaily.com)
Although recent progress in cardiovascular medicine has introduced major scientific and technological breakthroughs, heart disease has been the second cause of death in Japan and the leading cause of death in the entire world. (juntendo.ac.jp)

Research is needed to examine closely the cost effectiveness and acceptability of such an approach. (bmj.com)
The current "psychosocial environment" approach with its attention to of job control and other social risk factors has probably had its most effective use in explaining patterns of cardiovascular disease (CVD). (cdc.gov)
A 'Do No Harm' Novel Safety Checklist and Research Approach to Determine Whether to Launch an Artificial Intelligence-Based Medical Technology: Introducing the Biological-Psychological, Economic, and Social (BPES) Framework. (cdc.gov)

Objective To develop, validate, and evaluate a new QRISK model to estimate lifetime risk of cardiovascular disease. (bmj.com)
DESIGN, SETTING, AND PARTICIPANTS: Microsimulation modeling was used to estimate long-term benefits and harms for hypothetical US cohorts of men and women aged 40 to 79 years with up to 20% 10-year risk for an atherosclerotic CVD event and without prior history of CVD or elevated bleeding risks. (healthpartners.com)

We also use human stem cells as a test-tube model to study the process of heart formation and to create new human heart tissues and organs from these stem cells. (stanford.edu)
We first describe how and when the use of treatments by individuals in a prognostic study can influence the development or validation of a prognostic model. (biomedcentral.com)
Where relevant, the use of treatments should be considered in the analysis of prognostic model studies, particularly when a prognostic model is designed to guide the use of certain treatments and these treatments have been used by the study participants. (biomedcentral.com)
Future prognostic model studies should clearly report the use of treatments by study participants and consider the potential impact of treatment use on the study findings. (biomedcentral.com)
With leading research studies and initiatives at Georgia Heart Institute, our experts are collaborating with other physicians to study and advance heart care. (nghs.com)
The present study investigated whether the removal of organic acids (0%, 19%, 42%, 60%, and 79%) from cranberry juice by EDBM affects its antibacterial activity against major periodontopathogens as well as its anti-inflammatory properties in an oral epithelial cell model. (cranberryinstitute.org)
In the present study we test both a new model of job -related coronary heart disease (CHD) risk, and introduce a new technique for assessing the effects of job characteristics of detailed occupational groups. (cdc.gov)
In the study, Fidelle and colleagues first analyzed data in approximately 500 patients from the PREVALUNG trial , which included current or former smokers with cardiovascular disease who were part of a lung cancer screening program. (medscape.com)
This smaller, but population representative study in Rotterdam examined a similar research question. (cdc.gov)
The UK Biobank study defined development of dementia disease through linkage to healthcare records, while the more recently published Rotterdam study used research-grade diagnoses for this purpose. (cdc.gov)

Deacidification attenuated the anti-inflammatory effect of cranberry juice in an in vitro oral epithelial cell model. (cranberryinstitute.org)
Relating in vitro to in vivo exposures with physiologically based tissue dosimetry and tissue response models. (cdc.gov)

1 National policies now support targeting of interventions to reduce risk of cardiovascular disease among high risk patients. (bmj.com)
Ghanvatkar S, Kankanhalli A, Rajan V. User Models for Personalized Physical Activity Interventions: Scoping Review. (jmir.org)

Simplified fluid-structure interaction model of ventricular assist flow in the presence of contracting heart wall and aortic valve leaflets. (edu.au)

Patients with depression and healthy controls differ in several cardiovascular risk markers, putting patients at increased risk for CVDs. (frontiersin.org)
Markers of Cardiovascular Disease among Adults Exposed to Smoke from the Hazelwood Coal Mine Fire. (monash.edu)

What matters in a transferable neural network model for relation classification in the biomedical domain? (crossref.org)
DEBCM: Deep Learning-Based Enhanced Breast Invasive Ductal Carcinoma Classification Model in IoMT Healthcare Systems. (cdc.gov)
A deep learning model for the diagnosis of sacroiliitis according to Assessment of SpondyloArthritis International Society classification criteria with magnetic resonance imaging. (cdc.gov)

and Marek Michalak, the faculty's vice-dean of research and a professor in the Department of Biochemistry. (wun.ac.uk)

Subjects Patients aged 30-84 years who were free of cardiovascular disease and not taking statins between 1 January 1994 and 30 April 2010: 2 343 759 in the derivation dataset, and 1 267 159 in the validation dataset. (bmj.com)
Of the 10% of patients in the validation cohort classified at highest risk with either the lifetime risk model or the 10 year risk model, only 18 385(14.5%) were at high risk on both measures. (bmj.com)
The reliable identification of such high-risk individuals with no prior history of cardiovascular disease will undoubtedly be of great interest to patients and their providers for preventative care measures. (news-medical.net)
Therefore, we examined whether common physiological cardiovascular risk factors differ between patients with depression and healthy (non-depressed) controls, whether patients and controls differ in CRF, and whether higher CRF is associated with a lower cardiovascular risk in both patients and healthy controls. (frontiersin.org)
Additionally, we examined whether within the patient sample, cardiovascular risk factors differ between patients with mild, moderate and severe depression, and whether the relationship between symptom severity and cardiovascular risk is moderated by patients' CRF levels. (frontiersin.org)
Compared to healthy controls, patients with depression had a higher cardiovascular risk as evident from about half of the examined indicators. (frontiersin.org)
In contrast, people with good CRF show more favourable cardiovascular risk scores, a relationship which was observed in both healthy controls and patients with depression. (frontiersin.org)
To validate the model, the team performed the same assessment of blood and feces samples on more than 100 patients in the LIFSCREEN trial who have Li-Fraumeni syndrome, a rare genetic disorder that increases a person's risk for cancer. (medscape.com)

A cardiovascular information system is a data-driven system in which research material and clinical information software along with scientific advancement data are stored. (prnewswire.com)
The system is an integrated haemodynamic system which is data-driven patient informatics it is capable of storing all the information related to cardiovascular disease patient. (prnewswire.com)
We introduce here the Research CardioVascular SIMulator ( RCVSIM ) software in order to complement research with the experimental data sets provided by PhysioBank. (physionet.org)
and other respected institutions, provides a way to capture medical images and patient data to create specific blood flow simulation and analysis models. (stanfordchildrens.org)

In this manuscript, we aim to provide insight into the problems that arise when treatment use is ignored when developing or validating a prognostic model. (biomedcentral.com)

It focuses on patient-specific modeling in pediatric and congenital heart disease, as well as adult cardiovascular disease. (stanfordchildrens.org)

Anatomy3

Diseases3

Analytical, Diagnostic and Therapeutic Techniques and Equipment9

Psychiatry and Psychology3

Disciplines and Occupations20

Anthropology, Education, Sociology and Social Phenomena5

Humanities2

Information Science8

Named Groups1

Health Care15

Geographicals1

Diseases18

Centre3

Cardiac17

20234

20221

Biomarkers5

20204

20192

Preclinical2

Measuring cardiovascular risk1

Outcomes5

Atherosclerosis1

Researchers7

Mortality3

Convolutional neural network1

Health17

Proportional hazard2

Epidemiology2

Biomedical research1

Patient's risk1

Translational research1

Physiology2

Prevention6

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Systematic review2

Rodent3

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Vascular4

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Therapeutic3

Pulmonary2

Innovation2

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Diabetes7

Methods5

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Faculty2

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Study10

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Data4

Manuscript1

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