Modeled models cardiovascular. Medical search. Frequent questions

We sought to assess whether AI model had knowledge of cardiovascular disease (CVD) racial disparities, including disparities associated with CVD risk factors and associated diseases. (medrxiv.org)
Cardiovascular diseases (CVDs) are the leading cause of death, with 31% of global mortality. (ump.edu.my)

A study reinforces the usefulness of ACC/AHA CVD Pooled Cohort risk equations and the importance of efforts to implement the current guidelines to prevent atherosclerotic cardiovascular disease in African Americans. (acpinternist.org)
With the increase in aging and cardiovascular risk factors, the morbidity and mortality of atherosclerotic cardiovascular disease (ASCVD), represented by ischemic heart disease and stroke, continue to rise in China. (biomedcentral.com)
Atherosclerotic cardiovascular disease (ASCVD), which mostly involves heart attacks and strokes caused by atherosclerosis, is one of the main causes of death worldwide [ 1 ]. (biomedcentral.com)

Journal of Cardiovascular Magnetic Resonance, 17 (1). (essex.ac.uk)
Background Mathematical modeling of cardiovascular magnetic resonance perfusion data allows absolute quantification of myocardial blood flow. (essex.ac.uk)

Students can perform activities such as observing agglutination reactions in blood typing , exploring blood components, and identifying different cardiovascular and blood pathologies with Carolina materials. (carolina.com)

High-density lipoprotein (HDL), the carrier of so-called "good" cholesterol, serves as the major athero-protective lipoprotein and has emerged as a key therapeutic target for cardiovascular disease. (biologicmodels.com)

Data collection and analysis: Two authors independently assessed each abstract for eligibility and extracted data on characteristics of the experimental model used, intervention and outcome measures. (ox.ac.uk)

Aims: Estimation of prognosis in pulmonary arterial hypertension (PAH) has been influenced by that various risk stratification models use different numbers of prognostic parameters, as well as the lack of a comprehensive and time-saving risk assessment calculator. (lu.se)
Ignoring treatments in prognostic model development or validation can affect the accuracy and transportability of models. (biomedcentral.com)
We aim to quantify the extent to which the effects of treatment have been addressed in existing prognostic model research and provide recommendations for the handling and reporting of treatment use in future studies. (biomedcentral.com)
We first describe how and when the use of treatments by individuals in a prognostic study can influence the development or validation of a prognostic model. (biomedcentral.com)
We subsequently conducted a systematic review of the handling and reporting of treatment use in prognostic model studies in cardiovascular medicine. (biomedcentral.com)
The use of treatments has been partly considered by the majority of CVD prognostic model studies. (biomedcentral.com)
Where relevant, the use of treatments should be considered in the analysis of prognostic model studies, particularly when a prognostic model is designed to guide the use of certain treatments and these treatments have been used by the study participants. (biomedcentral.com)
Future prognostic model studies should clearly report the use of treatments by study participants and consider the potential impact of treatment use on the study findings. (biomedcentral.com)
An important part of prognostic research is the development and validation of prognostic models or risk scores. (biomedcentral.com)
In practice, however, such prognostic models are often derived from or validated in data sets where a proportion of the individuals has received that specific treatment. (biomedcentral.com)
In this manuscript, we aim to provide insight into the problems that arise when treatment use is ignored when developing or validating a prognostic model. (biomedcentral.com)
First, we elaborate on how and when treatment use could negatively impact prognostic modelling. (biomedcentral.com)
Following this, we provide evidence of the scale of this issue in published studies by means of a systematic literature review of the reporting and handling of treatment use in cardiovascular prognostic model research. (biomedcentral.com)
We conclude with suggestions for the handling and reporting of treatment use in prognostic model research. (biomedcentral.com)

The geometric models in this repository are collected from past research projects in the Cardiovascular Biomechanics Research Laboratory at Stanford University. (simtk.org)
The geometric models in this repository are mostly built from imaging data of healthy and diseased individuals. (simtk.org)
A more up-to-date repository of cardiovascular models can be found at http://www.vascularmodel.com/sandbox/doku.php . (simtk.org)

The Million Hearts Model, a US Centers for Medicare & Medicaid Services (CMS) initiative that encouraged and paid healthcare organizations to assess and reduce cardiovascular disease (CVD) risk, reduced first-time myocardial infarction (MI) and strokes among Medicare beneficiaries without significant changes in Medicare spending, a randomized trial finds. (medscape.com)
We validated the accuracy of each model in detecting reduced myocardial blood flow in stenotic vessels versus gold-standard invasive methods. (essex.ac.uk)
Distributed parameter modeling showed excellent accuracy in detecting reduced myocardial blood flow in all stenotic vessels. (essex.ac.uk)

Graphical summary of recent contributions of our group regarding the influence of signaling cascades in the regulation of cellular and tissue processes involved in human pathophysiology (mostly performed in animal models of human disease). (uam.es)

The encouraging findings from the Million Hearts Model suggest that modernized payment models may be an affirmative strategy to [incentivize guideline-concordant CVD preventive care and improve outcomes], though further work is needed to ensure that these models are patient-centric, optimally deployed, and equity-enhancing," add the editorial writers. (medscape.com)
Effect of ghrelin on mortality and cardiovascular outcomes in experimental rat and mice models of heart failure: a systematic review and meta-analysis. (ox.ac.uk)
There were insignificant changes in cardiac output (SMD 0.28, 95% CI -0.24 to 0.80, P=0.29) and left ventricular end systolic pressure (MD 1.48, 95% CI -3.86 to 6.82, P=0.59).ConclusionsThe existing data provides evidence to suggest that Ghrelin may lower the risk of mortality and improve cardiovascular outcomes. (ox.ac.uk)
Project outcomes were strengthened community-academic partnerships, certification of community partners in conducting human subjects research, development of a randomized controlled design to test the intervention's efficacy, an interactive PowerPoint presentation, an informational pamphlet, the certification of 6 lay health advisors and 22 role models to provide the intervention, and an assessment tool using an audience response system. (cdc.gov)

A unique cardiovascular disease (CVD) risk calculator for black adults may not be necessary, a study found, despite that fact that current prediction models were developed with predominantly white populations. (acpinternist.org)
Using data from the Jackson Heart Study (JHS), a community-based study of 5,301 black adults in Jackson, Miss., researchers developed and validated risk prediction models for CVD incidence in black adults, incorporating standard risk factors, biomarkers, and subclinical disease. (acpinternist.org)
Traditional ASCVD prediction models (Framingham and China-PAR models) were constructed in the test set. (biomedcentral.com)
Currently, the most commonly used survival analysis method is the Cox proportional hazards model, and most traditional ASCVD prediction models are constructed based on this model. (biomedcentral.com)
Further, it focuses on the development of various forms of local risk prediction models and simple heart risk scores using non-laboratory features and machine learning (ML) algorithms. (ump.edu.my)
In developing risk prediction models, two ML algorithms, linear support vector machine and artificial neural network outperformed the existing conventional logistic regression analysis (LRA) model. (ump.edu.my)
Secondly, the ML models offer better and consistent risk prediction models as compared to LRA-based model. (ump.edu.my)

We therefore evaluated the various European Society of Cardiology (ESC)-/European Respiratory Society (ERS)-based three-and four-strata risk stratification models and established a comprehensive internet-based calculator to facilitate risk assessment. (lu.se)
In acromegaly, a severe disease that is often diagnosed late, morbidity and mortality rates are high, particularly as a result of associated cardiovascular, cerebrovascular, and respiratory disorders and malignancies. (medscape.com)

For better prevention and intervention, relevant guidelines recommend using predictive models for early detection of ASCVD high-risk groups. (biomedcentral.com)
Finally, the predictive capability of valid NLHRS models has also been tested and adjusted for different strata of the population. (ump.edu.my)

Mathematical models are widely used in biomechanics to represent the contractile activity of living organs. (houstonmethodist.org)

HA) and neuraminidase (NA) influenza genes in viru- ance mechanisms exist in bacteria, and NRIs have consis- lence in the mouse model. (cdc.gov)

Statistical analysis included the C statistic, a measure used to estimate the probability that a model is able to predict an outcome, with values ranging from 0.5, indicating that the outcome is no different than chance, to 1.0, in which the model predicts the outcome perfectly. (acpinternist.org)
However, the conversion of a complex form of ML algorithms into a simple statistical model is the prime concern. (ump.edu.my)
This conversion from a complex black-box nature of ML algorithms into simple statistical models yielded such models, which do not require automated systems for their implementation. (ump.edu.my)

Objective To develop, validate, and evaluate a new QRISK model to estimate lifetime risk of cardiovascular disease. (bmj.com)
DESIGN, SETTING, AND PARTICIPANTS: Microsimulation modeling was used to estimate long-term benefits and harms for hypothetical US cohorts of men and women aged 40 to 79 years with up to 20% 10-year risk for an atherosclerotic CVD event and without prior history of CVD or elevated bleeding risks. (healthpartners.com)
This report demonstrates how the Prevention Impacts Simulation Model (PRISM) can be incorporated in evaluations to estimate cumulative longer-term impacts of SDOH initiatives. (cdc.gov)
The warppartial least square method was utilized to estimate the multi-layer hypothesized path model. (ump.edu.my)
The index of these weights is referred to as NLHRS, which was further used as a covariate in the simple LRA model to estimate the likelihood of CVDs. (ump.edu.my)

This model found novel pathways in which demographic and socioeconomic features are the main drivers of behavioral features, leading to CVDs status directly and indirectly through metabolic syndrome. (ump.edu.my)

1 National policies now support targeting of interventions to reduce risk of cardiovascular disease among high risk patients. (bmj.com)
System dynamics modeling is an underused tool for informing and refining public health interventions. (cdc.gov)

IMPORTANCE: The US Preventive Services Task Force (USPSTF) is updating its 2016 recommendation on the use of aspirin for the primary prevention of cardiovascular disease (CVD) and colorectal cancer (CRC). (healthpartners.com)

Methods To assess ChatGPT's responses to topic in cardiovascular disease disparities, we created six questions of twenty sets, with each set consisting of three questions with changes to text prompt based on differences in patient demographics. (medrxiv.org)
To assess this flow diverting strategy for popliteal aneurysms, flow profiles and thrombus formation likelihood were investigated in popliteal aneurysm models. (springer.com)

At baseline, both the original SPAHR/COMPERA and the updated SPAHR models, using up to six parameters, provided the highest accuracy (uAUC = 0.73 for both models) in predicting 1-, 3-, and 5-year mortality. (lu.se)
At baseline, utilizing the original or the updated SPAHR models using up to six parameters was favourable, the latter model additionally offering sub-characterization of the intermediate risk group. (lu.se)
Our findings support the 2022 ESC/ERS pulmonary hypertension guidelines' strategy for risk stratification suggesting the utilization of a three-strata model at baseline and a simplified four-strata model at follow-ups. (lu.se)
Seventy-nine articles (26%) excluded treated individuals from their analysis, 80 articles (26%) modelled treatment as an outcome, and of the 155 articles that developed a model, 86 (55%) modelled treatment use, almost exclusively at baseline, as a predictor. (biomedcentral.com)

Different models' discrimination and calibration degrees were compared to find the optimal prediction model for this population according to different genders and further analyze the risk factors of ASCVD. (biomedcentral.com)
By comparing the discrimination and calibration degrees of each model, the RSF showed the best prediction performance in males and females (male: Area Under Curve (AUC) 0.791 (95%CI 0.767,0.813), C statistic 0.780 (95%CI 0.730,0.829), Brier Score (BS):0.060, female: AUC 0.759 (95%CI 0.734,0.783) C statistic was 0.737 (95%CI 0.702,0.771), BS:0.110). (biomedcentral.com)
ML-based NLHRS and their associated models outperformed the existing semi-quantitative risk score-based model in terms of discrimination and calibration assessments. (ump.edu.my)

Cox proportional hazards models in the derivation cohort to derive risk equations accounting for competing risks. (bmj.com)

An impaired HRV was observed at 12 months of age in PLP-α-syn female but not in male mice, indicative of cardiovascular AF. (frontiersin.org)
The aim of the study is to determine the effect of Ghrelin on mortality and cardiac function in experimental rats/mice models of HF.MethodsData sources: PUBMED, Scopus. (ox.ac.uk)
Search methods: We systematically searched for all controlled trials (upto November 2014) which assessed the effects of Ghrelin (irrespective of dose, form, frequency, duration and route of administration) on mortality and cardiac function in rats/ mice models of HF. (ox.ac.uk)

Permission is granted to use these models for research purposes, but not for commercial use. (simtk.org)
Finally, we have recently initiated a research line aimed at deciphering some of the tissue, cell and molecular aspects that differentiate female and male responses to nutrient overload, insulin resistance, obesity and cardiovascular health. (uam.es)
Horizons in World Cardiovascular Research. (novapublishers.com)
2Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Islamic Republic of Iran. (who.int)
The goal of the CBPR process used in ECL was to build infrastructure to conduct translational research, design materials and methods salient to the community, recruit and train lay health advisors and role models, and develop an assessment instrument. (cdc.gov)

Age-sex centile values for lifetime cardiovascular risk compared with 10 year risk estimated using QRISK2 (2010). (bmj.com)
Of the 10% of patients in the validation cohort classified at highest risk with either the lifetime risk model or the 10 year risk model, only 18 385(14.5%) were at high risk on both measures. (bmj.com)
This is because age has such a dominant effect in calculating absolute cardiovascular risk. (bmj.com)
Model performance was compared with the American College of Cardiology/American Heart Association (ACC/AHA) CVD risk algorithm (Pooled Cohort Equations) and the Framingham Risk Score (FHS) refitted to the JHS data. (acpinternist.org)
Six models composed of different risk variables were constructed and externally validated using 2 independent black adult data sets from the Atherosclerosis Risk in Communities (ARIC) study and the Multi-Ethnic Study of Atherosclerosis (MESA). (acpinternist.org)
However, the reclassification improvement was not substantially different between model 6 and the ACC/AHA CVD Pooled Cohort risk equations or between model 6 and the FHS. (acpinternist.org)
Researchers assessed the Million Hearts CVD Risk Reduction Model in a pragmatic, cluster-randomized trial among 342 healthcare organizations - half in the intervention group and half in the standard care control group. (medscape.com)
The model was unique in paying for overall CVD risk reduction, measured by a novel, longitudinal risk calculator, rather than tying performance-based payments to control of individual risk factors," the authors write. (medscape.com)
Risk scores were calculated using the original Swedish Pulmonary Arterial Hypertension Registry (SPAHR)/Comparative, Prospective Registry of Newly Initiated Therapies for Pulmonary Hypertension (COMPERA) three-strata model, the updated SPAHR three-strata model with divided intermediate risk, and the simplified three-parameter COMPERA 2.0 four-strata model. (lu.se)
At follow-ups, the updated SPAHR model with divided intermediate risk (7-11 parameters) provided the highest accuracy for 1-, 3-, and 5-year mortality (uAUC = 0.90), followed by the original SPAHR/COMPERA model (7-11 parameters) (uAUC = 0.88) and the COMPERA 2.0 model (uAUC = 0.85). (lu.se)
Our findings furthermore support the utility of the updated SPAHR model with divided intermediate risk, when a more comprehensive assessment is needed at follow-ups, complementing the three-parameter COMPERA 2.0 model. (lu.se)
Our results support the 2022 ESC/ERS pulmonary hypertension guidelines' risk stratification strategy, additionally suggesting the updated SPAHR three-strata model with divided intermediate risk, as a promising complement to the new simplified three-parameter COMPERA 2.0 four-strata strategy, when a more comprehensive overview is needed. (lu.se)
The NLHRS and their associated models which are the outputs of novel methodology provide valid and simple forms of risk scores and can be used without automated systems. (ump.edu.my)

We also use human stem cells as a test-tube model to study the process of heart formation and to create new human heart tissues and organs from these stem cells. (stanford.edu)
Collaboration with VASA Therapeutics : characterization a heart failure model with preserved ejection fraction (HFpEF) / Dahl salt sensitive rats. (syncrosome.com)
Using diets to model human disease, our group has studied the response of several metabollicaly-relevant organs and tissues as the heart, adipose tissue or the liver to pathological insults such as nutrient overload. (uam.es)

Indeed, women have been reported to develop initially motor symptoms, with men exhibiting mainly cardiovascular dysfunction ( 13 ). (frontiersin.org)

There were consistent themes in incorrect or hedging responses by ChatGPT, with 91% and 79% of incorrect and hedging responses related to a cardiovascular disease disparity that affects a minority or underserved racial group. (medrxiv.org)
Given that these models might be used by the general public, caution should be advised in taking responses at face value. (medrxiv.org)
Continuum mechanics is an appealing framework to model the active responses of active soft biological tissues at the macroscale. (houstonmethodist.org)

OBJECTIVE: To provide updated model-based estimates of the net balance in benefits and harms from routine use of low-dose aspirin for primary prevention. (healthpartners.com)
We used the Prevention Impacts Simulation Model (PRISM) in a rapid evaluation to better understand the implementation and potential impact of MCPs' SDOH initiatives. (cdc.gov)

Many studies in MSA patients have already depicted cardiovascular autonomic impairments with a reduction in sympathetic and parasympathetic activities ( 6 - 9 ). (frontiersin.org)
In the mixed-effects model using random intercepts of country and parallel of latitude, time was significantly associated with a reduction of seropositivity (IRR = 0.899, 95% CI = 0.891-0.907), but local sampling was significantly associated with increased seropositivity (IRR = 2.477, 95% CI = 2.316-2.649). (who.int)

The model parameters were determined by cross-validation and parameter tuning and then verified in the training set. (biomedcentral.com)
The distributed parameter model can also be used for absolute quantification but has not been applied in patients with coronary artery disease. (essex.ac.uk)
We assessed whether distributed parameter modeling might be less dependent on arterial input function saturation than Fermi modeling in healthy volunteers. (essex.ac.uk)
We performed both single and dual bolus analysis of these data using the distributed parameter and Fermi models. (essex.ac.uk)
Conclusions Comparison of single bolus versus dual bolus values suggests that distributed parameter modeling is less dependent on arterial input function saturation than Fermi modeling. (essex.ac.uk)

The models discriminated reasonably well in the ARIC and Multi-Ethnic Study of Atherosclerosis data (C statistic range, 0.70 to 0.77). (acpinternist.org)
As a validated model that estimates impact using available implementation data, PRISM is a useful tool for rapid evaluation of SDOH initiatives. (cdc.gov)
This saturation effect is evident during application of standard Fermi models in single bolus perfusion data. (essex.ac.uk)
We also performed analysis using both models of single bolus data obtained from five patients with coronary artery disease and findings were compared against independent invasive coronary angiography and fractional flow reserve. (essex.ac.uk)

Geometric models of cardiovascular applications in VTK/XML PolyData format. (simtk.org)
In this chapter, we illustrate, exemplify, and discuss the implementation of these two formulations of mechanical activity through three applications to cardiovascular mechanics. (houstonmethodist.org)

These models covered a bent and a straight anatomy in three configurations: control, single-lined and dual-lined Supera stents. (springer.com)

Therefore, this study aims to establish a population ASCVD prediction model in rural areas of Xinjiang using survival analysis. (biomedcentral.com)
The purpose of this study is two folds such as the development of a statistically valid path model which considered the possible non-linear paths, mediators, and binary endogenous feature of CVDs status. (ump.edu.my)
Firstly, the study concludes that the adoptions of the flexible approach in estimation can model the binary feature of CVDs and non-linear paths in the complex path models. (ump.edu.my)

Coronary Stents (Cardiovascular) - Global Market Analysis and Forecast Model (COVID-19 Market Impact) is built to visualize quantitative market trends within Cardiovascular Devices therapeutic area. (marketresearch.com)

The cardiovascular AF in MSA is thought to be mainly due to a progressive neurodegeneration of several areas involved in autonomic control of the cardiovascular system such as inter alia , cholinergic neurons in the ventrolateral ambiguous nucleus and dorsal motor nucleus of the vagus nerve ( 5 ). (frontiersin.org)

Robust methodologies and sources enable the model to provide extensive and accurate overview of the market. (marketresearch.com)

Subjects Patients aged 30-84 years who were free of cardiovascular disease and not taking statins between 1 January 1994 and 30 April 2010: 2 343 759 in the derivation dataset, and 1 267 159 in the validation dataset. (bmj.com)

Larger multi-centre studies are encouraged to validate the utility of the updated SPAHR model. (lu.se)

The model discusses in detail the impact of COVID-19 on Coronary Stents market for the year 2020 and beyond. (marketresearch.com)

MMP2 and 9 KO and prototype pharmacological inhibitors protect from structural changes and functional deficit in animal HF models. (syncrosome.com)

This model estimated warped coefficients using the overall linear trend found in linear segments of non-linear relationships. (ump.edu.my)
In the fixed-effects model, time was significantly associated with increased seropositivity (IRR = 1.025, 95% CI = 1.021-1.030), but no significant association was found for local sampling (IRR = 1.026, 95% CI = 0.988-1.065). (who.int)

Cardiovascular disease is the leading cause of premature death and a major cause of disability in the UK. (bmj.com)

Diseases2

Atherosclerotic cardiovascular disease3

Magnetic resonance2

Pathologies1

Therapeutic target1

Abstract1

Prognostic14

Repository3

Myocardial3

Pathophysiology1

Outcomes4

Prediction models7

Respiratory2

Predictive2

Mathematical1

Bacteria1

Statistical3

Estimate5

Pathways1

Interventions2

Cancer1

Assess2

Baseline4

Discrimination and calibration3

Proportional1

Mice3

Research5

Risk13

Heart3

Symptoms1

Responses3

Prevention2

Reduction2

Parameter5

Data4

Applications2

Anatomy1

Study3

Analysis1

System1

Provide1

Patients1

Validate1

Impact1

Animal1

Found2

Major1