AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPsychiatry and PsychologyPhenomena and ProcessesDisciplines and OccupationsTechnology, Industry, AgricultureInformation ScienceNamed GroupsHealth Care
Models, BiologicalComputer SimulationAlgorithmsTime FactorsReproducibility of ResultsKineticsModels, TheoreticalModels, StatisticalSensitivity and SpecificityCrystallizationProspective StudiesTreatment OutcomeMathematicsPredictive Value of TestsMonte Carlo MethodThermodynamicsModels, GeneticNonlinear DynamicsAnalysis of VarianceTemperatureModels, ChemicalLikelihood FunctionsPrognosisImage Processing, Computer-AssistedRetrospective StudiesArea Under CurveBody WeightSoftwareBayes TheoremRegression AnalysisBiomechanical PhenomenaReference ValuesBiological MarkersLinear ModelsDose-Response Relationship, DrugImage Interpretation, Computer-AssistedData Interpretation, StatisticalMagnetic Resonance ImagingHydrogen-Ion ConcentrationSperm MotilityRats, WistarSeverity of Illness IndexStochastic ProcessesImaging, Three-DimensionalROC CurveBlood PressureStatistics, NonparametricCrystallography, X-RayFollow-Up StudiesWaterCase-Control StudiesHemodynamicsHeart RateBiometryStatistics as TopicProbabilityImage EnhancementModels, MolecularPregnancyAdministration, OralHalf-LifeSperm CountMarkov ChainsModels, NeurologicalPharmacokineticsDiffusionEquipment DesignLiverDisease Models, AnimalSemenRisk FactorsOrgan SizeX-Ray DiffractionBlood Flow VelocityBrainCattleBreedingAge FactorsNormal DistributionSpermatozoaBiophysicsSignal Processing, Computer-AssistedRats, Sprague-DawleyTomography, X-Ray ComputedSwineOxygenMultivariate AnalysisMolecular Sequence DataPhenotypeMetabolic Clearance RateContrast MediaElasticityHemoglobinsHematologic TestsComputational BiologyDouble-Blind MethodModels, CardiovascularDogsCalibrationPhantoms, Imaging
ArterialBiomechanicsSimulateVascularBiomechanicalMathematicalPathologicalDiseasesComputational fluid dyBiologicalCharacteristicsSimulation resultsSciencesSoft tissueSystemClinicalBoundary conditionsElasticHumanConditionsHealthComputerDataCaptureQuestionCareHighMethodSetsAspectsHandPotentialUniversityAnimal
Arterial3
  • 2) The role of pulsatile arterial load (vascular stiffness in particular) in cardiovascular function. (pitt.edu)
  • This study describes a multidimensional 3D/lumped parameter (LP) model which contains appropriate inflow/outflow boundary conditions in order to model the entire human arterial trees. (sharif.edu)
  • A new extensive LP model of the entire arterial network (48 arteries) was developed including the effect of vessel diameter tapering and the parameterization of resistance, conductor and inductor variables. (sharif.edu)
Biomechanics5
  • Department faculty members have teaching and research expertise in areas related to cardiovascular and fluid biomechanics, musculoskeletal biomechanics, biomaterials and tissue engineering, bioinstrumentation, biosystems, biomedical imaging, biological signal analysis, bioinformatics and computational biology, respiratory and pulmonary engineering, and other allied fields. (uiowa.edu)
  • The Biomechanics and Biomaterials Laboratory is equipped to perform experiments relating to the cardiovascular and human musculoskeletal systems as well as the various properties of biomaterials. (uiowa.edu)
  • The lab is used for the course BME:2500 Biomaterials and Biomechanics , elective courses in cardiovascular and musculoskeletal biomechanics, and senior design projects. (uiowa.edu)
  • Mascheroni, P., Penta, R., Merodio, J. (2023) The impact of vascular volume fraction and compressibility of the interstitial matrix on vascularised poroelastic tissues Biomechanics and Modeling in Mechanobiology, 22, pp. 1901-1917. (gla.ac.uk)
  • Miller, L., Penta, R. (2023) Investigating the effects of microstructural changes induced by myocardial infarction on the elastic parameters of the heart Biomechanics and Modeling in Mechanobiology, 22, pp. 1019-1033. (gla.ac.uk)
Simulate1
  • In this study, Computational Fluid Dynamics (CFD) techniques are used to model and simulate the gas flow in the melt nozzle area for a convergent-divergent, close-coupled gas atomiser in the absence of the melt stream. (unav.edu)
Vascular3
  • The Vascular Model Repository , a sister project of SimVascular, is a library of computational models of normal and diseased human cardiovascular and pulmonary anatomy and input and output boundary conditions for various physiologic states. (github.io)
  • One of the hypotheses being investigated is that aberrant vascular stiffness changes are involved in the genesis of certain cardiovascular pathologies (e.g., preeclampsia, isolated systolic hypertension in elderly). (pitt.edu)
  • 3) Cardiovascular actions of relaxin and its therapeutic potential in the context of three pathologies: (i) relaxin-induced maternal vascular remodeling and associated functional benefits in preeclampsia, (ii) relaxin-induced left atrial remodeling and suppression of atrial fibrillation, and (iii) relaxin-induced left ventricular remodeling and associated functional benefits in the setting of diastolic dysfunction. (pitt.edu)
Biomechanical2
  • The scope of our research ranges from the study of flow and transport processes in blood and biological fluids in the cardiovascular system and artificial organs to biomechanical aspects of the cardiovascular and the skeleto-muscular system and medical devices. (re-place.be)
  • We hereby strive towards integration of research at different levels - often starting from a clinical problem or question - and combining computer modelling (from simple lumped parameter models to full 3D-simulation of biomechanical and fluid-structure interaction problems), experimental (hydraulic and test bench) work and in vivo data to explore and unravel the problem. (re-place.be)
Mathematical3
  • In addition to basic and translational research, Dr. Shroff and colleagues have developed and continue to develop novel, simulation-based material (i.e., mathematical models of biological systems and associated "virtual experiments") for education and engineering design. (pitt.edu)
  • Mathematical Biology is the application of mathematical modelling to solve problems in biology and physiology. (gla.ac.uk)
  • Biological models include the use of mathematical equations, computers, and other electronic equipment. (lookformedical.com)
Pathological1
  • What is the role of bioelectricity under physiological and pathological conditions? (gla.ac.uk)
Diseases3
  • It is well known to reduce the risk of cardiovascular diseases and also avoid the risk of gaining weight. (autocityscotland.co.uk)
  • Aetna considers the use of chelation therapy experimental and investigational in the prevention and treatment of cancer, cardiovascular disease (e.g., atherosclerotic cardiovascular disease , coronary artery disease, individuals who had a myocardial infarction), neurodegenerative diseases (e.g. (aetna.com)
  • Cardiovascular diseases (CVDs), including thrombosis, which is certainly induced by platelet aggregation, will be the leading reason behind mortality world-wide. (aboutsciencenow.info)
Computational fluid dy1
  • In this review, we introduce the concept of computational fluid dynamics (CFD) modeling with a clinical perspective and we review the CFD models used to study RE from the fluid mechanics point of view. (unav.edu)
Biological2
  • He was the recipient of the Established Investigator Award from the AHA (1986-1991) and was elected as a Fellow of the American Physiological Society (1988), Fellow of the American Institute for Medical and Biological Engineering (1999), Fellow of Biomedical Engineering Society (2007), and Fellow of International Academy of Medical and Biological Engineering (2020). (pitt.edu)
  • The global temperature of the solution and the local temperature at the nanoparticle (NP) surface determine the protein corona composition/content, which in turn affects the biological effects of NPs and the corresponding physiological responses. (sharif.edu)
Characteristics3
  • A two-dimensional, seven link, nine degrees of freedom biped model was developed to investigate the dynamic characteristics of normal and transfemoral amputee locomotion during the entire gait cycle. (sharif.edu)
  • The process of cumulative change over successive generations through which organisms acquire their distinguishing morphological and physiological characteristics. (lookformedical.com)
  • Many researchers have already introduced behavior-aware protocols for a better understanding of architecture and realistic modeling of behavioral characteristics, similarities, and aggregation of mobile users. (unincol.edu.co)
Simulation results1
  • The simulation results show how similarly these two parameters modify gas mass flow rates, gas velocity fields, aspiration pressures in the melt delivery tube or the size of the recirculation zones below the melt nozzle. (unav.edu)
Sciences1
  • Dr. Shroff has been serving as the Principal Investigator on a NIH-NHLBI pre-doctoral training grant (Cardiovascular Bioengineering Training Program) since 2005 and the Coulter Translational Research Partnership II Program since 2013, and Co-Director on a NIH-NHLBI post-doctoral training grant (Training Program in Imaging Sciences in Translational Cardiovascular Research) since 2016. (pitt.edu)
Soft tissue1
  • Although the facilities for soft tissue modeling have improved and the precise CT-imaging of human head has revealed novel details of brain, skull and the interface (the meninges), a comprehensive FEM model of TBI is still being studied. (sharif.edu)
System6
  • The final goal can be a better understanding of a patho-physiological problem, a better quantification (and diagnosis) of the function of an (artificial) organ or system, or design of new or improved medical devices for a better patient treatment. (re-place.be)
  • Conventional models of cardiovascular system frequently lack required detail and focus primarily on the overall relationship between pressure, flow and volume. (sharif.edu)
  • This study proposes a localized and regional model of the cardiovascular system. (sharif.edu)
  • It is well known that the modern understanding of the cardiovascular system undoubtedly starts with the work of William Harvey (1578-1657) who published his discovery of the circulation of blood in 1628. (scirp.org)
  • A model of blood buffer system. (physiome.cz)
  • A quasidynamic model of the blood buffer system. (physiome.cz)
Clinical5
  • Computational models of human physiology offer the potential, with clinical data, to create patient-specific models that capture a patient's physiological status. (springeropen.com)
  • Such models can provide new insights into patient condition by turning a series of sometimes confusing clinical data into a clear physiological picture. (springeropen.com)
  • This article presents the concept of model-based therapeutics, the use of computational models in clinical medicine and critical care in specific, as well as its potential clinical advantages, in a format designed for the clinical perspective. (springeropen.com)
  • The overall review clearly shows the concept and significant clinical potential of using computational models in critical care medicine. (springeropen.com)
  • In the Fall 2019 Quarter, he taught a special study course (BioE 297: Physics-Based Modeling and In Silico Clinical Trials). (ucsf.edu)
Boundary conditions1
  • Realistic boundary conditions and Navier-Stokes equations in healthy and stenosed models of carotid artery bifurcation. (sharif.edu)
Elastic2
  • frictional, elastic and hydraulic were considered for the prosthetic joints of the amputee and their design parameters were optimized to achieve the closest. (sharif.edu)
  • In fact, although in the introduction to the problem (paragraphs 1-8), Euler focuses on the discussion on blood flow through arteries, to such a degree to even proposing adhoc models for the behavior of their elastic cross-sections, surprisingly, and also somehow disappointing, is that the main body of the manuscript (paragraphs 9-34) is devoted to the modeling of flows through rigid tubes, driven by a piston pump. (scirp.org)
Human1
  • Abierto Inglés The fast expansion of ICT (information and communications technology) has provided rich sources of data for the analysis, modeling, and interpretation of human mobility patterns. (unincol.edu.co)
Conditions1
  • There are many different parameter sets saved within this JSim project file, modeling different conditions for a Sodium Potassium pump. (nih.gov)
Health2
  • Monounsaturated fats have a positive effect on overall health by improving body composition and reducing cardiovascular risks. (autocityscotland.co.uk)
  • The amount of this intrinsic absorption can be used to determine the physiological health of an organ-for example, whether the tissue is getting sufficient oxygenated blood flow. (nationalacademies.org)
Computer2
  • A computer aided-design (CAD) algorithm was proposed to efficiently handle the coupling of two or more 3D models with the LP model, and substantially lessen the coupling processing time. (sharif.edu)
  • Large animal models and computer simulations indicate that adding non-contractile material to the damaged left ventricular wall can potentially reduce myofiber stress. (ucsf.edu)
Data1
  • According to these data types I investigated and implemented willowy payment models, such as pay- per-use, prepaid, and dues models. (wgc2010.sk)
Capture1
Question1
  • and yet it remains a question due to physiological, geometrical and computational complications. (sharif.edu)
Care3
  • However, protocolized care does not address the variability of outcome due to inter- and intra-patient variability, both in physiological state, and the response to disease and treatment. (springeropen.com)
  • A focus of this paper is that the model-based methods discussed here can provide patient-specific care that is robust to these intra- and inter-patient variabilities. (springeropen.com)
  • They thus help first jS, and because of this they care well lumped 25:42)02 services. (cypressfineart.com)
High1
  • As can be seen in 4B, less physiological slope conductance is associated with a relatively high degree of voltage-dependent reversal. (nih.gov)
Method2
  • The equations of motion were derived using the Lagrange method and the stance foot-ground contact was simulated using a five-point penetration model. (sharif.edu)
  • The proposed method of parameter estimation for hydraulic electric analogy model is recursive least squares algorithm. (sharif.edu)
Sets1
  • Models numbered 5 and greater have the corresponding parameter sets saved within the .proj file (e.g. (nih.gov)
Aspects1
  • These aspects directly address questions concerning what makes a model, how it is made patient-specific, what it can be used for, its limitations and, importantly, what constitutes sufficient validation. (springeropen.com)
Hand1
  • Stage A generally starts as a small lump in the palm of the hand, often just under the digit on the palmar crease. (biomedcentral.com)
Potential1
  • At the pump reversal potential, in the case of the "standard" concentrations for the model, this occurs at -200mV. (nih.gov)
University1
  • Working with a faculty steering committee, Dr. Hay led the redesign of the entire university budget away for historical budgeting to an RCM model. (arizona.edu)
Animal1