DiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesDisciplines and OccupationsHealth Care
Postoperative Nausea and VomitingAntiemeticsNauseaDroperidolOndansetronVomitingMetoclopramideAnesthesia, GeneralGynecologic Surgical ProceduresAcupressureAmbulatory Surgical ProceduresPain, PostoperativeNitrous OxideDouble-Blind MethodGranisetronAnalgesics, OpioidPreanesthetic MedicationAcupuncture PointsPropofolSerotonin 5-HT3 Receptor AntagonistsAnesthetics, IntravenousAnalgesia, Patient-ControlledAnesthesia, ConductionPostoperative ComplicationsAnesthesia Department, HospitalFentanylAnesthesia Recovery PeriodObstetric Surgical ProceduresAcupunctureAnesthesia, IntravenousMyringoplastyMorphineAnesthesia, InhalationAlfentanilStrabismusIntraoperative PeriodProspective StudiesDexamethasoneSerotonin AntagonistsPruritusInjections, IntravenousAnesthetics, InhalationIntraoperative CareQuinolizinesNeostigmineSufentanilAnesthesia, ObstetricalCholecystectomy, LaparoscopicLaparoscopyAnesthetics, CombinedOxygen Inhalation TherapyTreatment OutcomePiperidinesAnesthesiaRandomized Controlled Trials as TopicAnestheticsSingle-Blind MethodDrug Administration ScheduleAnalgesia, EpiduralAnesthesia, SpinalMethyl EthersHysterectomyPain MeasurementDrug Therapy, CombinationIsofluranePostoperative PeriodPatient SatisfactionDose-Response Relationship, DrugAnesthetics, LocalInfusions, IntravenousAnalgesicsMotion Sickness
PONVAnalgesiaAnalgesicChemotherapyOpioidsIntraoperativeAnesthesiaPost-operatInitiate the vomitiAcutePatientsMotion sicknessOndansetronComplicationsSurgeryIntravenousAbdominalPreventionSedationIncidencePruritus2021Anesth AnalgPredictOutcomesPathophysiologyDizzinessPredictiveCisplatinAntagonistsSerotoninInterventionAnesthesiologyDrugsPainEfficacyManagementImmuneMeta-AnalysisPrognostic modelChronicDrugCare
PONV15
Analgesia13
  • In the postoperative period, VAS and Colorado analgesic scores were lower for the dogs that received the higher nalbuphine dose, which only required supplemental analgesia 10 h following its administration, compared with dogs that received the lower dose. (scielo.br)
  • Epidural nalbuphine significantly reduces the intra-operative isoflurane requirement and provides prolonged postoperative analgesia after ovariohysterectomy in dogs. (scielo.br)
  • A comparison of extradural and intravenous methadone on intraoperative isoflurane and postoperative analgesia requirements in dogs. (scielo.br)
  • Torske KE, Dyson DH, Pettifer G. End tidal halothane concentration and postoperative analgesia requirements in dogs: a comparison between intravenous oxymorphone and epidural bupivacaine alone and in combination with oxymorphone. (scielo.br)
  • We conclude that intrathecal midazolam 2.5mg provided moderate prolongation of postoperative analgesia when used as an adjunct to bupivacaine. (ispub.com)
  • Spinal anesthesia with bupivacaine is administered routinely for lower limb surgery 1 and provides effective analgesia in the early postoperative period. (ispub.com)
  • Various adjuvants have been added to spinal local anesthetic to prolong postoperative analgesia. (ispub.com)
  • Intrathecal morphine provides effective postoperative analgesia but is associated with adverse effects such as itching, nausea, urinary retention, sedation, ileus and life-threatening respiratory depression. (ispub.com)
  • The optimum dose of intrathecal midazolam for postoperative analgesia is not identified. (ispub.com)
  • For instance, brief periods (less than 24 hours) of postoperative analgesia can be facilitated by adding an opioid to the local anesthetic injected into the cerebrospinal fluid. (medscape.com)
  • Prolonged postoperative analgesia is best ensured by insertion of an epidural catheter, using an opioid and local anesthetic combination infused continuously over the first few postoperative days. (medscape.com)
  • Various regional analgesia techniques exist that can be used to promote postoperative pain relief. (medscape.com)
  • Opioids administered to the IT space can offer effective postoperative analgesia. (medscape.com)
Analgesic6
  • The OPRM1 A118G polymorphism does not play a significant role in post-operative fentanyl analgesic dose or post-operative nausea, vomiting and dizziness in patients undergoing radical gastrectomy. (spandidos-publications.com)
  • To measure the change in the minimum alveolar concentration of isoflurane (EtISO) associated with epidural nalbuphine and the postoperative analgesic requirements in dogs after ovariohysterectomy. (scielo.br)
  • 9. Marucio RL, Luna SP, Neto FJ, Minto BW, Hatschbach E. Postoperative analgesic effects of epidural administration of neostigmine alone or in combination with morphine in ovariohysterectomized dogs. (scielo.br)
  • In this prospective, randomized, double- blind study, we investigated the postoperative analgesic efficacy of intrathecal midazolam 2.5mg as an adjunct to bupivacaine for spinal anesthesia in 80 patients undergoing lower limb orthopedic surgery. (ispub.com)
  • This article will focus on the use of regional anesthesia as a postoperative analgesic technique for orthopedic surgery. (medscape.com)
  • [ 1 ] The use of regional anesthetic and analgesic techniques can offer superior overall pain control and reduced postoperative opioid requirements. (medscape.com)
Chemotherapy9
  • Granisetron is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy and radiotherapy. (wikipedia.org)
  • It may be used for chemotherapy-induced nausea and vomiting and appears to work about the same as ondansetron. (wikipedia.org)
  • The most common side-effects of chemotherapy treatment are nausea, vomiting and diarrhea. (wikipedia.org)
  • Drugs.com Heron Therapeutics Announces FDA Approval of Sustol (granisetron) Extended-Release Injection for the Prevention of Chemotherapy-Induced Nausea and Vomiting FDA.gov Sustol Prescribing Information. (wikipedia.org)
  • 2. Jacob R, Aswathy AB, Sivadas A. Prospective Randomized case control study of Oral Aprepitant for the prevention of Chemotherapy-Induced Nausea and Vomiting (CINV). (rjptonline.org)
  • Palonosetron has been available internationally after being registered in the USA in 2003, and is indicated for the prevention of acute nausea and vomiting associated with highly emetogenic chemotherapy, and the prevention of nausea and vomiting associated with moderately emetogenic chemotherapy. (presseportal.ch)
  • Palonosetron is listed on the Pharmaceutical Benefits Scheme (PBS) from November 1st, 2010 for the management of nausea and vomiting associated with cytotoxic chemotherapy being used to treat malignancy which occurs within 48 hours of chemotherapy administration. (presseportal.ch)
  • Palonosetron (palonosetron hydrochloride) is a second generation 5-HT3 Receptor Antagonist, developed for the prevention of chemotherapy-induced nausea and vomiting (CINV) in patients with cancer, with a long half-life of 40 hours and at least 30 times higher receptor binding affinity than currently available compounds. (presseportal.ch)
  • Some studies have found ginger may help nausea caused by chemotherapy, but larger studies are needed to confirm these effects. (mskcc.org)
Opioids1
  • The surgeon estimates that the procedure will take 90 minutes, and predicts that she will require postoperative opioids for pain relief. (aafp.org)
Intraoperative1
  • Intraoperative Data Enhance the Detection of High-Risk Acute Kidney Injury Patients When Added to a Baseline Prediction Model. (cornell.edu)
Anesthesia4
Post-operat8
  • Post-operative nausea and vomiting: update on predicting the probability and ways to minimize its occurrence, with focus on ambulatory surgery Int J Surg. (bjan-sba.org)
  • The solution description is focused on aromatherapy as an effective means for dealing with post-operative nausea and vomiting. (place-4-papers.com)
  • The review of the literature stage is offered to inform about the data in the area of study and confirm that the chosen means for treating post-operative nausea and vomiting is a spread issue. (place-4-papers.com)
  • Overall, aromatherapy in combination with anti-emetic medication is considered as an effective tool in coping with post-operative nausea among adults which helps improve the effectiveness of the treatment and reduce the doses of anti-emetic medication (Hunt, Dienemann, Norton, Hartley, Hudgens, Stern, & Divine, 2013). (place-4-papers.com)
  • Statistically, post-operative nausea and vomiting among adults is a serious problem, which occurs in 20-30% cases within 24 hours (Gibbison & Spencer, 2009). (place-4-papers.com)
  • The focus of the study is an adult population experiencing post-operative nausea and vomiting immediately after the surgery. (place-4-papers.com)
  • Compounds of this class may prove to be more effective in man against delayed emesis induced by cisplatin, post-operative nausea and vomiting and motion sickness. (ox.ac.uk)
  • I don't use metoclopramide for post-operative nausea vomiting (prophylactic or treatment), but that's another blog post. (wakingupcosts.net)
Initiate the vomiti2
  • The released serotonin may stimulate the vagal afferents through the 5-HT 3 receptors and initiate the vomiting reflex. (nih.gov)
  • It is thought that chemotherapeutic agents produce nausea and vomiting by releasing serotonin from the enterochromaffin cells of the small intestine and that the released serotonin then activates 5-HT3 receptors that are located on the nerve terminals of the vagus in the periphery and centrally in the chemoreceptor trigger zone of the area postrema, to initiate the vomiting reflex. (com.bd)
Acute4
  • Is a possible therapy for nausea and vomiting due to acute or chronic medical illness or acute gastroenteritis[citation needed] Treatment of cyclic vomiting syndrome although there are no formal trials to confirm efficacy. (wikipedia.org)
  • Australians can now access a new drug to prevent acute (and delayed phase) nausea and vomiting which may occur in cancer patients undergoing chemotherapy1. (presseportal.ch)
  • The incidence of postoperative acute as well as chronic pain is very high which has a tremendous impact on the mother, family, healthcare providers, and healthcare delivery. (researchsquare.com)
  • Discussion and conclusion: ERAS with preoperative whey protein-infused CHO loading not only assured better surgical outcomes without increasing postoperative complications and readmission rate, but also achieved a superior preservation of nutritional status and muscle strength, as well as suppression of postoperative acute phase inflammatory marker among GC patients. (upm.edu.my)
Patients17
  • Prognostic models, like the one we developed in the previous article in this series, 1 yield scores to enable the prediction of the risk of future events in individual patients or groups and the stratification of patients by these risks. (bmj.com)
  • 2 A good model may allow the reasonably reliable classification of patients into risk groups with different prognoses. (bmj.com)
  • We need evidence that the model performs well for other groups of patients. (bmj.com)
  • Various statistical or clinical factors may lead a prognostic model to perform poorly when applied to other patients. (bmj.com)
  • The main ways to assess or validate the performance of a prognostic model on a new dataset are to compare observed and predicted event rates for groups of patients (calibration) and to quantify the model's ability to distinguish between patients who do or do not experience the event of interest (discrimination). (bmj.com)
  • Temporal validation -An alternative is to evaluate the performance of a model on subsequent patients from the same centre(s). 6 10 Temporal validation is no different in principle from splitting a single dataset by time. (bmj.com)
  • Which patients are likely to experience postoperative nausea and vomiting? (aafp.org)
  • Postoperative nausea and vomiting are uncomfortable for patients, can prolong hospitalization, and can lead to more serious complications, including aspiration pneumonia. (aafp.org)
  • Accurately predicting which patients are at risk of postoperative nausea and vomiting can help physicians decide when to recommend prophylactic antiemetics. (aafp.org)
  • A review found three predictive scores for postoperative nausea and vomiting and attempted to validate them in 1,444 patients. (aafp.org)
  • Ignoring CMI by monitoring only the untreated patients-whose outcomes remain unaltered-can inflate false alarm rates, because the evolution of both the model and clinician-ML interactions can induce complex dependencies in the data that violate standard assumptions. (deepai.org)
  • The capstone project is aimed at checking the effectiveness of the application of aromatherapy in combination with anti-emetic drugs compared to simply anti-emetic medication among adult patients experiencing post-operational nausea and vomiting. (place-4-papers.com)
  • High-risk patients experience nausea and vomiting in 60% case after operations (787.0 Nausea, 2013). (place-4-papers.com)
  • Understanding exactly how the drugs work is an important step toward eliminating problems like itching, nausea and vomiting after surgery, and post-operative cognitive decline in some older patients. (uthsc.edu)
  • Background: Enhanced Recovery after Surgery (ERAS) with preoperative sole carbohydrate (CHO) loading is widely proven in reducing the length of postoperative hospital stay (LPOHS) without increasing complications among gastrointestinal and gynaecologic cancer (GC) patients. (upm.edu.my)
  • This randomised controlled trial aimed to determine the effectiveness of ERAS with preoperative whey protein-infused CHO loading on postoperative outcomes among GC patients. (upm.edu.my)
  • Phytobezoars can occur in adult patients as a postoperative complication after gastric bypass or partial gastrectomy, especially when partial gastrectomy is accompanied by vagotomy. (msdmanuals.com)
Motion sickness1
Ondansetron1
Complications2
  • Postoperative complications include periods of gas-bloat syndrome (in which an increase in swallowed air makes it difficult to belch or vomit), abdominal distension, nausea, an increase in flatulence, and dysphagia (difficultly swallowing) due to post-surgical swelling at the wrapped site. (hdc.org.nz)
  • Postoperative outcomes including surgical outcomes, postoperative complications, nutritional (body composition, dietary intake and biochemical profile) and functional status (handgrip strength) were studied. (upm.edu.my)
Surgery3
Intravenous2
  • The problem description is focused on post-operation vomiting and the traditional treatment by means of intravenous injections of anti-emetic drugs. (place-4-papers.com)
  • Intravenous injections of the particular drug help cope with nausea and vomiting by means of neurochemical influence. (place-4-papers.com)
Abdominal1
  • Postoperative disrupted abdominal wall management by a new tissue expansion technique. (who.int)
Prevention1
  • Prevention of nausea and/or vomiting associated with initial and repeat courses of emetogenic cancer therapy, including high-dose cisplatin. (nih.gov)
Sedation1
Incidence3
  • Incidence of nausea in the PACU was significantly lower in the acupoint group as compared with the sham point group (32% vs. 56%, P = 0.029) and P6 sham group (32% vs. 64%, P = 0.002) but not as compared with the droperidol group (32% vs. 46%, P = ns). (silverchair.com)
  • Similarly, subjects in the acupoint group had a significantly lower incidence of vomiting in the PACU as compared with the sham point group (12% vs. 33%, P = 0.026) and P6 sham group (12% vs. 31%, P = 0.029) but not as compared with the droperidol group (12% vs. 18%, P = ns). (silverchair.com)
  • [ 5 ] The incidence of nausea and vomiting for IT morphine is approximately 20% and peaks at approximately 4 hours. (medscape.com)
Pruritus1
20211
  • World Health Organization model list of essential medicines: 22nd list (2021). (wikipedia.org)
Anesth Analg1
  • 2. P.S. Glass, P.F. White Practice guidelines for the management of postoperative nausea and vomiting: past, present, and future Anesth Analg. (bjan-sba.org)
Predict2
  • Evaluation of three risk scores to predict postoperative nausea and vomiting Acta Anaesthesiol Scand. (bjan-sba.org)
  • Monitoring the performance of machine learning (ML)-based risk prediction models in healthcare is complicated by the issue of confounding medical interventions (CMI): when an algorithm predicts a patient to be at high risk for an adverse event, clinicians are more likely to administer prophylactic treatment and alter the very target that the algorithm aims to predict. (deepai.org)
Outcomes2
  • This approach with a multidisciplinary involvement and collaboration is recommended to be integrated into routine perioperative nutritional intervention management in surgical oncology to ensure better postoperative outcomes. (upm.edu.my)
  • Several new sections have been added, including those about off-pump techniques, robotic coronary bypass, and the value of clinical guidelines and pathways for guiding postoperative care and improving outcomes. (wakingupcosts.net)
Pathophysiology1
  • 6. Singh P, Yoon SS, Kuo B. Nausea: a review of pathophysiology and therapeutics. (rjptonline.org)
Dizziness2
Predictive2
  • Internal validation -A common approach is to split the dataset randomly into two parts (often 2:1), develop the model using the first portion (often called the "training" set), and assess its predictive accuracy on the second portion. (bmj.com)
  • Predictive model of response to tafamidis in hereditary ATTR polyneuropathy. (cdc.gov)
Cisplatin1
  • Palonosetron did not inhibit the antitumor activity of cisplatin, cyclophosphamide, cytarabine, doxorubicin and mitomycin C in murine tumor models. (com.bd)
Antagonists2
  • Studies in animal models with NK1 antagonists suggest that these represent a new class of antiemetic agents having a broader spectrum of activity than 5-HT3 antagonists. (ox.ac.uk)
  • Thus, they have the potential to complement 5-HT3 antagonists and so provide a further advance in the management of nausea and vomiting. (ox.ac.uk)
Serotonin2
  • Palonosetron works by blocking the actions of Serotonin, associated with nausea and vomiting, at 5-HTs receptor. (com.bd)
  • Acupuncture was found to stimulate the release of β-endorphin, encephalin, endomorphin, dynorphin, and serotonin in animal models.5,6 These neurotransmitters were shown to modulate brainstem, thalamus, hypothalamus, and pituitary function in acupuncture-treated animals. (ndnr.com)
Intervention1
  • Intervention model: Parallel Assignment. (who.int)
Anesthesiology1
  • A simplified risk score for predicting postoperative nausea and vomiting: conclusions from cross-validations between two centers Anesthesiology. (bjan-sba.org)
Drugs1
  • Depending on the severity of nausea, nurses use either drugs or a combination of drugs to assure the immediate or fast remission. (place-4-papers.com)
Pain4
  • Inadequately managed postoperative pain after cesarean section has a number of consequences to the mother in the postoperative period. (researchsquare.com)
  • Different postoperative pain management modalities have been practiced after cesarean section over the years. (researchsquare.com)
  • All randomized trials comparing the efficacy of wound infiltration for postoperative pain management after cesarean section will be included. (researchsquare.com)
  • Regional anesthetic techniques provide an excellent means for managing postoperative pain following orthopedic procedures. (ispub.com)
Efficacy1
  • A Randomized Control Trial to Assess the Efficacy of Dry Ginger Powder on Management of Nausea and Vomiting Among Antenatal Mothers Attending Selected Urban Health Centres of Belgaum, Karnataka - One Group Pretest Post Test Pre Experimental Study. (rjptonline.org)
Management1
  • Fundoplication and postoperative management. (hdc.org.nz)
Immune1
Meta-Analysis1
  • Methods We performed a meta-analysis, using a random-effects model. (bmj.com)
Prognostic model2
  • To show that a prognostic model is valuable, however, it is not sufficient to show that it successfully predicts outcome in the initial development data. (bmj.com)
  • 1 3 In this article, we discuss how to evaluate the performance of a prognostic model in new data. (bmj.com)
Chronic2
  • Chronic Care Model - Chronic Care Model research papers discuss the organizational framework designed to improve the care for individuals with chronic conditions. (papermasters.com)
  • Research papers using the Chronic Care Model in nursing illustrate that there is a viable model of care that can be implemented in order for a patient to live successfully with a chronic disease. (papermasters.com)
Drug1
  • [ 2 ] However, caffeine was considered in one study as a potential drug of abuse and has even been described as a model drug of abuse. (medscape.com)
Care6
  • Time into postoperative care (hour) */ @66 POINMIN 2. (cdc.gov)
  • Time into postoperative care (minute) */ @68 POINTIME 2. (cdc.gov)
  • Time into postoperative care (type) */ @70 POUTHR 2. (cdc.gov)
  • Time out of postoperative care (hour) */ @72 POUTMIN 2. (cdc.gov)
  • Time out of postoperative care (minute) */ @74 POUTIME 2. (cdc.gov)
  • Time out of postoperative care (type) */ @76 DIAG1 $CHAR5. (cdc.gov)