MembraneECMOPatient'sCardiacExtra-corporeal circulationThrombus formationDialysisSystemicSurfacesInterventionVivoPerfusionBloodAnnalsAnesthesiologistsApproachClinicalCoronaryAbstractPulmonaryArtificial circulationTreatmentValveComputationalLiposomesAnalysesInventionsYearHeartPatientsMachineLungsSystemsResultsFindingsRiskSupportSurgeryStudiesSafetyPotential
Membrane5
- Some common blood-contacting devices include catheters, stents, vascular grafts, heart valve prostheses, and extracorporeal circulation/membrane oxygenation systems. (springer.com)
- BACKGROUND: We describe implementation, evaluate performance, and report outcomes from the first program serving an entire metropolitan area designed to rapidly deliver extracorporeal membrane oxygenation (ECMO)-facilitated resuscitation to patients with refractory ventricular fibrillation/ventricular tachycardia (VF/VT) out-of-hospital cardiac arrest (OHCA). (healthpartners.com)
- There is no consensus on the management of anticoagulation during extracorporeal membrane oxygenation (ECMO). (springeropen.com)
- During extracorporeal membrane oxygenation (ECMO), systemic anticoagulation is routinely used to avoid thrombin generation due to the contact of blood with non-biological surfaces of the extracorporeal circuit. (springeropen.com)
- One avenue of potential treatment in massive PE is the use of Extracorporeal Membrane Oxygenation, commonly known as ECMO. (emra.org)
ECMO1
- In brief, VA-ECMO provides both hemodynamic and respiratory support by offloading the responsibility for circulation from heart and oxygenation by the lungs. (emra.org)
Patient's3
- The Cardioband is implanted with the heart beating: it does not require any type of surgical incision into the chest wall, nor the aid of EC to keep the patient's extracorporeal circulation active. (mitralacademy.it)
- Compared to traditional planning, 3D printing technology has proven extremely useful in presurgical preparations , by converting the patient's two-dimensional image plane data into a 1:1 full- size model that surgeons can use to visualize and standardize a very complex procedure. (3dprint.com)
- Without following the explicit instructions, the device can only operate within the normal maximum temperature range of: 42 degrees C. The Blanketrol II 48 Degree C System can be used with adult and pediatric patients for extracorporeal circulation of the patient's limb, entire body, or a chemo medication lavage of the abdominal area. (icij.org)
Cardiac7
- In addition, other studies demonstrated that AngII activated platelet-derived growth factor-A (PDGF-A), a novel contributor to cardiac remodelling, to result in atrial fibrosis in pressure-overloaded mouse model [ 13 ] . (medsci.org)
- Entry criteria included: 1) adults (aged 18-75), 2) VF/VT OHCA, 3) no return of spontaneous circulation following 3 shocks, 4) automated cardiopulmonary resuscitation with a Lund University Cardiac Arrest System (LUCAS™), and 5) estimated transfer time of (healthpartners.com)
- The micro-device, released in the area of the valve where the regurgitation originates, is fastened without having to stop cardiac activity and without having to resort to Extracorporeal Circulation (EC, heart-lung machine) with identical results to the classic surgical treatment. (mitralacademy.it)
- His physicians had detected a mid- to high-risk STS score, short for Society of Thoracic Surgery score, a validated risk-prediction model for open surgery based on data from the STS National Adult Cardiac Surgery Database . (3dprint.com)
- In addition, the team developed the new type of occlude for the minimally invasive cardiac surgery and designed innovative arteriovenous catheters, which are also the main products and key technologies of Dongguan Kewei with two national invention patents and 33 patents for inventions, utility models and design. (microport.com)
- For the past several decades, the Society of Thoracic Surgeons (STS) has been leading the development of risk models and quality improvement monitoring with the STS National Cardiac Database. (medscape.com)
- Hemoglobinuric ATN can accompany various states of hemolysis, including transfusion reactions, malaria , snake and insect bites, glucose 6-phosphate dehydrogenase deficiency, and mechanical causes such as extracorporeal circulation and cardiac valvular prostheses. (medscape.com)
Extra-corporeal circulation2
- Only two vascular anastomosis were performed, without extra-corporeal circulation. (rbccv.org.br)
- Prevention of thrombus formation in extra corporeal circulation during haemodialysis. (medicines.org.uk)
Thrombus formation1
- In this study, four biomedical grade polymers were evaluated in a 4 h rabbit model of thrombogenicity for their effects on extracorporeal circuit thrombus formation and circulating platelet count. (newhaven.edu)
Dialysis1
- Establish an extracorporeal circulation channel for blood dialysis therapy. (bedfordmed.com)
Systemic1
- Extracorporeal Removal of Thermosensitive Liposomal Doxorubicin from Systemic Circulation after Tumor Delivery to Reduce Toxicities. (musc.edu)
Surfaces1
- Despite many improvements in CPB technology and circuit design, patients still undergo an intense inflammatory response when their blood comes in contact with the nonendothelial surfaces involved in extracorporeal circulation. (medscape.com)
Intervention2
- Intraoperative 3D Transesophageal Echocardiography to ensure the closure of each Valvuloplasty during surgical intervention and the successful weaning of the patient from the artificial circulation. (dunant.gr)
- Currently, Dongguan Kewei has set up high-standard production base mainly for its intervention and extracorporeal circulation products. (microport.com)
Vivo4
- We will also discuss some of the important techniques employed (using in vitro and in vivo models) to assess the hemocompatibility of any new material, including the measurement of platelet preservation, platelet and protein adhesion, the effect of flow rates on thrombosis, and the ultimate surface clot area. (springer.com)
- Both of these substances have been shown to suppress complement activation in in vivo animal models (Kalli et al. (justia.com)
- Related to these fields, I have expertise in ex vivo tissue studies, in vivo studies (rodents and large animals, including porcine and canine models) of thermal therapies and liposomal drug delivery, in development of novel therapeutic devices and experimental instrumentation, in vivo imaging and image processing, and computational modeling. (musc.edu)
- 5. Rossmann C, McCrackin MA, Armeson KE, Haemmerich D (2017), Temperature sensitive liposomes combined with thermal ablation: Effects of duration and timing of heating in mathematical models and in vivo. (musc.edu)
Perfusion3
- Model-based perfusion reconstruction (MBPR) by using a weighting sum of basis functions, is used to describe the dynamic contrast agent distribution by superposition of incorporated prior knowledge. (degruyter.com)
- Used in the extracorporeal circulation of blood for arterial perfusion, regional perfusion and cardiopulmonary bypass procedures only when used by an expert perpermist in the operation of TERUMOCARDIOVASCULAR SYSTEMS or similar equipment. (icij.org)
- The device is indicated for use in the extracorporeal circulation of blood for arterial perfusion and cardiopulmonary bypass procedures by a perfusionist. (icij.org)
Blood9
- Here we demonstrate that acutely injured human lungs declined for transplantation, including a lung that failed to recover on EVLP, can be recovered by cross-circulation of whole blood between explanted human lungs and a Yorkshire swine. (nature.com)
- The clinic established by Amosov, produced about 7000 lung resections, more than 95000 operations for heart diseases, including about 36,000 operations with extra-corporeal blood circulation. (wikipedia.org)
- Each year, the institute fulfilled about 3000 heart operations, including over 1500 - with extra-corporeal blood circulation. (wikipedia.org)
- [1] In the 1880s, Max von Frey and Max Gruber tested the first closed system for oxygenation and returning the blood through arteries in a canine model. (sts.org)
- [4] In 1934, Dr. John Gibbon, considered the father of extracorporeal circulation, began constructing a machine to achieve blood oxygenation. (sts.org)
- Products by artery, vein pipe, tube, infusion heating tube, displacement adsorption connecting pipe, a pressure sensor filter channel connecting pipe and blood purification accessories according to the clinical treatment of extracorporeal circulation pattern configuration into the whole crowd. (tianyimedical.cn)
- This product can be used as extracorporeal circulation of the blood passages after connecting with blood dialyzer or hemodialysis filtration apparatus or blood filtration device. (tianyimedical.cn)
- Platelet preservation for this optimal NO release formulation was 97% of baseline after 4 h, and clot area was 0.9 cm2 compared to 5.2 cm2 for controls, demonstrating that combining E2As with NO release provides a truly advanced hemocompatible polymer coating for extracorporeal circuits and potentially other blood contacting applications. (newhaven.edu)
- Post-dilution is the favorite model for the infusion line, so the high blood flow will be of prime importance [ 1 - 4 ]. (scitechnol.com)
Annals1
- Cardiovascular Diseases, Children's Heart and Vascular Diseases, Clinical Physiology of Circulation, Annals of Arrhythmology, Russian Journal of Thoracic and Cardiovascular Surgery, Creative Cardiology. (rusannsurg.com)
Anesthesiologists2
- At the same time, collaboration with selected anesthesiologists and extracorporeal circulation specialists ensures the best immediate and long-term results for the surgical patients. (dunant.gr)
- Undoubtedly, improved risk modeling and preoperative planning can help anesthesiologists deliver better patient care. (medscape.com)
Approach2
- Our findings suggest that cross-circulation can serve as a complementary approach to clinical EVLP to recover injured donor lungs that could not otherwise be utilized for transplantation, as well as a translational research platform for immunomodulation and advanced organ bioengineering. (nature.com)
- The program provides a potential model of this approach for other communities. (healthpartners.com)
Clinical1
- The addition of key condition-specific clinical data points at the time of hospital admission will dramatical y improve model performance. (who.int)
Coronary1
- 2] A prediction model that and transparency of such risk adjustment models, and to widen uses a `history of coronary heart disease' as a risk factor to predict discussion on the strengths and limitations of risk adjustment models death from an acute myocardial infarction (AMI) is always going based on service claims data. (who.int)
Abstract1
- abstract = "The pathogenesis of organ injury induced by extracorporeal circulation involves many inflammatory cascades and cellular components of the immune system. (johnshopkins.edu)
Pulmonary3
- Fig. 5: Maintenance of pulmonary airways and alveolar-capillary barrier after 24 h of xenogeneic cross-circulation. (nature.com)
- However, studies in pigs undergoing CPB with a standard extracorporeal circuit or a heparin-coated CPB circuit found less pulmonary injury in the heparin-coated group of animals. (johnshopkins.edu)
- In contrast to adult primary pulmonary hypertension, the newborn syndrome is not defined by a specific pressure of the pulmonary circulation. (medscape.com)
Artificial circulation1
- Attempts to develop a heart-lung machine date back as far as 1813 with an idea proposed by Le Gallois about what would constitute artificial circulation. (sts.org)
Treatment2
- Amosov elaborated a number of new methods of surgical treatment of heart lesions, the original model of heart-lung machine. (wikipedia.org)
- IDM/DXS treatment led to preservation of myocardial ultrastructure with less damage, and amelioration of the fetal and placental circulation. (biomedcentral.com)
Valve2
- one millimetre thick and from 5 to 7 cm long - applied under the valve with a suture model similar to the sartorial stitches made by a sewing machine. (mitralacademy.it)
- Instead, surgeons tend to choose TAVR valve replacement surgery because it is minimally invasive, does not require extracorporeal circulation, and has a high rate of post-surgery recovery. (3dprint.com)
Computational1
- Methods: A computational fluid dynamics (CFD) model was developed. (eur.nl)
Liposomes1
- Computer Modeling of Drug Delivery with Thermosensitive Liposomes in a Realistic Three-Dimensional Geometry. (musc.edu)
Analyses2
- Fig. 3: Multiscale analyses of human lungs over the course of 24 h of xenogeneic cross-circulation. (nature.com)
- In general, model reporting should conform to published reporting standards, and attempts should be made to test model validity by using sensitivity analyses. (who.int)
Inventions1
- He is the author and co-author of more than 3700 scientific publications including more than 250 books, more than 100 inventions and utility models, more than 300 computer programs and databases, some of which are registered abroad, designed for various problems of cardiоvascular surgery, cardiology, medical education and medical science organizing. (rusannsurg.com)
Year2
- Identification of M. chimaera infection in 6 patients prompted an outbreak investigation at the University Hospital Zurich, a 900-bed tertiary-care hospital in Zurich, Switzerland, that performs ≈700 open-heart surgeries that use extracorporeal circulation per year. (cdc.gov)
- Lео A. Bockeria perfoms the entire known plurality of heart operations in the most various pathologies: 3-6 operations daily, that is 700-900 operations with extracorporeal circulation a year. (rusannsurg.com)
Heart3
- Under the leadership of Amosov fundamental studies of the self-regulation of the heart systems were conducted and the issues of machine diagnosis of heart disease were studied, elaboration and creation of physiological models of "internal environment", computer modeling of basic mental functions, and some socio-psychological mechanisms of human behavior were done. (wikipedia.org)
- ORLOFF, M. J. - A simplified model for heterotopic rat heart transplantation. (rbccv.org.br)
- The Neochord technique does not envisage the use of the extracorporeal circulation (EC) machine either as it is implemented with the heart beating: it only requires a small lateral cut in the chest (minithoracotomy) of just 6-8 centimetres. (mitralacademy.it)
Patients1
- Individual thromboembolic risk for patients can be estimated using validated risk stratification model. (medicines.org.uk)
Machine1
- In particular, the limitations of machine learning prediction models should be understood, and these models should be appropriately developed, evaluated and reported. (who.int)
Lungs1
- Fig. 1: Maintenance of explanted human lungs using a xenogeneic cross-circulation platform. (nature.com)
Systems1
- In 2019, Discovery Health published a risk adjustment model to determine standardised mortality rates across South African private hospital systems, with the aim of contributing towards quality improvement in the private healthcare sector. (who.int)
Results1
- Our results indicate that IDM/DXS promotes a better gestational outcome at least partially by reducing stress response during and after the operation of IUBAV in the goat model. (biomedcentral.com)
Findings1
- Latest research findings through the mouse model claim that attenuation of Wnt/-catenin signaling could be in charge of these adjustments [30]. (tech-strategy.org)
Risk3
- When designing a risk prediction model, patient-proximate variables with a sound theoretical or proven association with the outcome of interest should be used. (who.int)
- As more SA private sector medical to be inferior to a model that uses `current admission to hospital for funders explore their use, it is important that the quality of the AMI' as a risk factor. (who.int)
- However, risk factors that capture the degree models be improved. (who.int)
Support1
- Cross-circulation for extracorporeal support and recovery of the lung. (nature.com)
Surgery2
- These devastating infections result from aerosols generated by contaminated heater-cooler units used with extracorporeal circulation during surgery. (cdc.gov)
- Growing evidence supports airborne transmission resulting from aerosolization of M. chimaera from contaminated water tanks of heater-cooler units (HCUs) that are used with extracorporeal circulation during surgery ( 3 , 4 ). (cdc.gov)
Studies1
- Many recent studies in both animal models and humans have revealed that renin-angiotensin system (RAS) activation is one of the most vital mechanisms involved in atrial fibrosis [ 1 , 4 ] . (medsci.org)
Safety1
- There is growing evidence that these 3D-printed models improve patient safety and accuracy by decreasing operative times. (3dprint.com)
Potential1
- En annan metod att dosera heparin med hjälp av ett patientnära instrument har också testats, men utan att kunna minska heparinets negativa effekt på blodplasmas trombinbildande potential. (5dok.org)