AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPsychiatry and PsychologyPhenomena and ProcessesDisciplines and OccupationsAnthropology, Education, Sociology and Social PhenomenaTechnology, Industry, AgricultureInformation ScienceNamed GroupsHealth CareGeographicals
Cardiovascular DiseasesDisease Models, AnimalRisk FactorsHypertensionAtherosclerosisBiological MarkersCohort StudiesProspective StudiesRisk AssessmentBlood PressureFollow-Up StudiesMetabolic Syndrome XObesityInflammationCross-Sectional StudiesDiabetes Mellitus, Type 2PrevalenceDiabetes MellitusMice, Inbred C57BLTime FactorsDyslipidemiasC-Reactive ProteinProportional Hazards ModelsBody Mass IndexIncidenceUnited StatesCholesterolLipidsCause of DeathAge FactorsSmokingLife StyleSex FactorsCoronary DiseaseCombined Modality TherapyHomocysteineTreatment OutcomeCholesterol, HDLCholesterol, LDLStrokeRiskPrimary PreventionDiabetes ComplicationsDiabetic AngiopathiesDietPredictive Value of TestsCardiovascular SystemOxidative StressTriglyceridesCase-Control StudiesMice, KnockoutDiagnostic ImagingMyocardial InfarctionMice, TransgenicChronic DiseaseHyperlipidemiasEndothelium, VascularJapanKidney Failure, ChronicBlood GlucoseHypercholesterolemiaHuntington DiseaseCoronary Artery DiseasePhenotypeKidney DiseasesNeoplasmsGenetic Predisposition to DiseaseHydroxymethylglutaryl-CoA Reductase InhibitorsNeurodegenerative DiseasesHypolipidemic AgentsAgingMultivariate AnalysisModels, BiologicalComorbiditySignal TransductionCells, CulturedCalcinosisSex DistributionCarotid Intima-Media ThicknessLongitudinal StudiesRenal DialysisMortalityDisease ProgressionVascular DiseasesInsulin ResistanceAnalysis of VarianceAntihypertensive AgentsCardiovascular AgentsEuropean Continental Ancestry GroupArteriosclerosisRisk Reduction BehaviorExercisePolymorphism, Single NucleotideQuestionnairesCarotid ArteriesPrognosisRegression AnalysisRetrospective StudiesHeart DiseasesMagnetic Resonance Imaging
Computed tomographyCenters for DiseasInterventionsOutcomesEpidemiologyAssessmentClinicalType 2 diabetEvaluateCardiacCoronary arteryRenal diseaseBranchMechanismsPredictionImagingDisordersAcuteDifferencesPandemicApproachesRetrospectiveDiabetesForecastsReconstructionHypertensionPatientsTreatmentMedianIschemicProportionalPrevalenceStrokeMortalityExperimentalFindingsDevelopmentResearchManagementMethodsRegistryJournalHigh-riskCasesStatusAdultsPerformance
Computed tomography1
  • Although computed tomography angiography (CTA) is the preferred imaging modality used by radiologist for diagnosing AAA, computed tomography (CT) images can be used too. (sharif.edu)
Centers for Diseas2
  • Hypertension, or abnormally high blood pressure, is common in the US, affecting approximately 45% of adults ( Centers for Disease Control and Prevention, National Center for Health Statistics, 2018 ). (elifesciences.org)
  • Hypertension is a risk factor for heart disease and stroke and causes or contributes to nearly half a million deaths a year ( Centers for Disease Control and Prevention, 2019 ). (elifesciences.org)
Interventions3
  • Cardiovascular Interventions, 16(8), e012527. (ottawaheart.ca)
  • Technical Recommendations for Computed Tomography Guidance of Intervention in the Right Ventricular Outflow Tract: Native RVOT, Conduits and Bioprosthetic Valves: A White Paper of the Society of Cardiovascular Computed Tomography (SCCT), Congenital Heart Surgeons' Society (CHSS), and Society for Cardiovascular Angiography & Interventions (SCAI). (ottawaheart.ca)
  • Journal of the Society for Cardiovascular Angiography and Interventions. (ottawaheart.ca)
Outcomes5
  • Long-Term Survival, Cardiovascular, and Functional Outcomes after Minimally Invasive Coronary Artery Bypass Grafting in 566 Patients. (ottawaheart.ca)
  • The primary intent is to mitigate cardiovascular dysfunction while optimizing cancer outcomes. (nih.gov)
  • The purpose of this Funding Opportunity Announcement (FOA) is to stimulate collaborative applications that will contribute to the identification and characterization of patients at risk of developing cancer treatment-related cardiotoxicity with the primary intent to mitigate cardiovascular dysfunction while optimizing cancer outcomes. (nih.gov)
  • A standardized definition of AKI has been proposed by the Kidney Disease: Improving Global Outcomes (KDIGO) AKI working group, which identifies and stages AKI based on changes in serum creatinine from baseline or a decrease in urine output (oliguria) as shown below. (medscape.com)
  • A more comprehensive approach to CVD risk management taking into account disease factors such as severity and anticardiolipin antibody status may be necessary to improve CVD outcomes in this high-risk population. (bmj.com)
Epidemiology2
  • They were experts with international reputations in echocardiography and environmental or cardiovascular epidemiology. (cdc.gov)
  • Based on best practice in other fields and recent insights in infectious disease epidemiology, one can maximise the predictive performance of such forecasts if multiple models are combined into an ensemble. (nsf.gov)
Assessment1
  • Application of Cardiovascular Computed Tomography to the Assessment of Patients With Hypertrophic Cardiomyopathy. (ottawaheart.ca)
Clinical5
  • This study aimed to explore the correlation between preoperative CVD and PNDs, as well as combine logistic regression and ROC curves to construct a clinical prediction PND model. (bvsalud.org)
  • Next, we constructed a clinical prediction PND model by drawing the receiver operating characteristic (ROC) curve. (bvsalud.org)
  • We defined and assessed value drivers and willingness to pay among stakeholders in several settings, outlined the patient journey and market access landscape, defined the clinical and economic value story for the client's technology, and identified likely payment models. (healthadvances.com)
  • Objectives We aimed to describe the rate and determinants of carotid plaque progression and the onset of clinical cardiovascular disease (CVD) in a UK SLE cohort. (bmj.com)
  • The following list shows potential International Classification of Diseases, Ninth Revision, Clinical Modification diagnoses that could indicate candidacy for LT. The number of patients hospitalized with these primary and secondary diagnoses is enormous. (medscape.com)
Type 2 diabet2
Evaluate5
  • In the recent years, a new ultrasound technology, called ultrasound biomicroscopy (UBM) was optimized to evaluate animal models of human disease. (hindawi.com)
  • We placed the coronary stent INC-1 on a rabbit and dog models so we can evaluate efficacy and security of the device in relationship to its biomechanical properties including navigation capacity, traceability, symmetric expansion, and safety, as well as endothelial attachment, thrombogenicity, and lack of involvement of secondary branches in these models. (scielo.org.mx)
  • We developed strategic frameworks that could be leveraged by the company to evaluate new disease area opportunities over time. (healthadvances.com)
  • To accomplish this, methods that evaluate cardiovascular risk prior to treatment and integrate evidence-based cancer treatment regimens with cardiovascular screening, diagnostic, and/or management strategies are sought. (nih.gov)
  • 4 The exact contribution of inflammatory burden, renal disease and a procoagulant state in the context of long-term corticosteroid and immunosuppressant therapy can be difficult to evaluate. (bmj.com)
Cardiac4
  • The Burke lab focuses on gene expression changes that drive cardiomyopathy progression including epigenetic mechanisms, paracrine control via fibroblast and myocyte crosstalk, and cardiac-derived endocrine mechanisms contributing to disease phenotype. (emory.edu)
  • However, cardiac dysfunction is encountered frequently among stroke patients, even in the absence of primary heart disease. (justia.com)
  • Patients can develop myocardial injuries after stroke even when patients do not have pre-existing cardiac diseases. (justia.com)
  • Atherosclerotic plaque rupture is the leading cause of cardiovascular death resulting from acute coronary syndrome (ACS) and leads to cardiac remodeling and fibrosis following ACS. (archivesofmedicalscience.com)
Coronary artery2
  • Real-world approach to comprehensive artificial intelligence-aided CT evaluation of coronary artery disease in 530 patients: A retrospective study. (ottawaheart.ca)
  • The efficacy of inspiratory muscle training in patients with coronary artery disease: Protocol for a systematic review and meta-analysis. (ottawaheart.ca)
Renal disease2
  • Adequate pre-dialysis care reduces mortality among end-stage renal disease (ESRD) patients. (cdc.gov)
  • Chronic kidney disease (CKD) occurs among approximately 30% of these individuals and a proportion of them will develop end-stage renal disease (ESRD) ( Powars et al , 1991 ). (cdc.gov)
Branch2
  • ATSDR received considerable assistance in this work from the Cardiovascular Diseases Branch of the Centers for Disease Control & Prevention (CDC). (cdc.gov)
  • As part of the public health response to COVID-19, the CDC Infectious Diseases Pathology Branch (Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases) was consulted on autopsies of 8 patients with laboratory evidence of SARS-CoV-2 by reverse transcription PCR (RT-PCR) on respiratory swab specimens collected either before or after death. (cdc.gov)
Mechanisms1
  • Innovators across healthcare sectors are working to change this reality, through novel modalities and mechanisms, precision medicine approaches, devices and combination products, and digital solutions. (healthadvances.com)
Prediction2
  • STAN outperforms traditional epidemiological models such as susceptible-infectious-recovered (SIR), susceptible-exposed-infectious-recovered (SEIR), and deep learning models on both long-term and short-term predictions, achieving up to 87% reduction in mean squared error compared to the best baseline prediction model. (nsf.gov)
  • While it is clear that traditional cardiovascular disease (CVD) risk factors play an important role, 3 several studies have demonstrated that disease-specific factors are also important and as a result, traditional risk prediction models perform poorly in SLE. (bmj.com)
Imaging1
Disorders1
  • Provided herein are methods for the prevention and treatment of cardiovascular diseases and disorders in a subject diagnosed as having suffered a cerebrovascular injury by administering agents that contain or induce the expression of microRNA-126. (justia.com)
Acute4
  • The role of coronary stents in the treatment of ischemic heart disease, both in its acute and chronic behavior, is now well established, and it is currently the most common modality for the performance of coronary artery bypass graft 3 , 4 . (scielo.org.mx)
  • For patient education information from eMedicineHealth, see the Diabetes Center , as well as Acute Kidney Failure and Chronic Kidney Disease . (medscape.com)
  • An ongoing pandemic of coronavirus disease (COVID-19) is caused by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). (cdc.gov)
  • The ongoing global pandemic of coronavirus disease (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was identified in Wuhan, Hubei Province, China, and has spread rapidly around the world ( 1 , 2 ). (cdc.gov)
Differences3
  • Sex Differences in Thoracic Aortic Disease and Dissection: JACC Review Topic of the Week. (ottawaheart.ca)
  • The human immune system displays remarkable variation between individuals, leading to differences in susceptibility to autoimmune disease. (iscb.org)
  • Differences by nativity status for cardiovascular disease (CVD) risk factors have been previously reported. (cdc.gov)
Pandemic2
  • and (3) integrating pandemic transmission dynamics into a deep learning model. (nsf.gov)
  • Presenteeism and job satisfaction among hospital environmental service workers during the COVID-19 pandemic: A moderated mediation model. (ottawaheart.ca)
Approaches1
Retrospective1
  • The Manhattan Lupus Surveillance Program (MLSP) is a population-based retrospective registry of cases with SLE and related diseases including pDLE in Manhattan and was used to provide estimates of the prevalence and incidence of pDLE across major racial/ethnic populations. (cdc.gov)
Diabetes1
  • and low high-density lipoprotein and can lead to the development of coronary heart disease and diabetes (1). (cdc.gov)
Forecasts5
  • Short-term forecasts of infectious disease burden can contribute to situational awareness and aid capacity planning. (nsf.gov)
  • We retrospectively explored alternative methods for ensemble forecasts, including weighted averages based on models' past predictive performance. (nsf.gov)
  • Over 52 weeks, we collected forecasts from 48 unique models. (nsf.gov)
  • Across all horizons and locations, the ensemble performed better on relative WIS than 83% of participating models' forecasts of incident cases (with a total N=886 predictions from 23 unique models), and 91% of participating models' forecasts of deaths (N=763 predictions from 20 models). (nsf.gov)
  • For an early-stage biopharmaceutical company, Health Advances assessed the global opportunity and developed sales forecasts for two cardiovascular indications. (healthadvances.com)
Reconstruction1
  • The basic modalities include B-mode, M-mode, Doppler mode, 3D reconstruction, power mode, and an ECG-based Kilo-Herz visualization technology. (hindawi.com)
Hypertension1
  • Taken together, modeling of the baseline hazard function of hypertension suggests that there are no true controls and that controls in logistic regression are cases with a late age of onset. (elifesciences.org)
Patients2
  • Patients were classified into two groups: the CVD group with a confirmed diagnosis and the non-cerebrovascular disease (NCVD) group. (bvsalud.org)
  • The postoperative survival of all patients was tracked, and a survival curve was constructed and incorporated into the Cox proportional hazard regression model to analyze the relationship between preoperative CVD and overall postoperative survival rate. (bvsalud.org)
Treatment4
  • Without limitation, some embodiments comprise methods, systems, and/or compositions relating to microRNAs and/or cell based therapies and the use of the same in the research, diagnosis, or treatment of injury or disease. (justia.com)
  • MiR-126 facilitates vascular re-modeling, decreases fibrosis in multiple organs, and has been reported to be beneficial in the treatment of atherosclerosis and re-stenosis. (justia.com)
  • To date, there have been few effective modalities in the treatment of cardiovascular disease and/or disorder subsequent to stroke, including in subjects with a glucose metabolism disorder. (justia.com)
  • The present disclosure provides a method for the treatment or prevention of a cardiovascular disorder or disease in a subject who has suffered cerebrovascular injury, the method comprising administering a therapeutically effective amount of a miR-126 containing agent or an agent that induces expression of miR-126 to the subject in need thereof. (justia.com)
Median2
  • Each week we created an ensemble forecast, where each predictive quantile was calculated as the equally-weighted average (initially the mean and then from 26th July the median) of all individual models' predictive quantiles. (nsf.gov)
  • Among several choices of ensemble methods we found that the most influential and best choice was to use a median average of models instead of using the mean, regardless of methods of weighting component forecast models. (nsf.gov)
Ischemic1
Proportional2
  • Given that the lifetime risk is so high, we first investigated whether a proportional hazards model in time-to-event analysis yields a better fit than logistic regression. (elifesciences.org)
  • Second, as time-to-event analysis assumes that the event will occur, that is, that every individual will become hypertensive if they live long enough, we investigated a proportional hazards model including a fraction of individuals that will never become hypertensive and hence are true epidemiological controls. (elifesciences.org)
Prevalence1
  • The Philadelphia Telemedicine Glaucoma Detection and Follow-Up Study reports the prevalence and risk factors for cataracts in individuals screened and examined for glaucoma and other eye diseases. (cdc.gov)
Stroke1
  • The major causes of death in stroke-related moralities are a consequence of neurological damage and/or cardiovascular complications. (justia.com)
Mortality2
  • Cardiovascular-related morbidity and mortality remain the world's number one killer. (healthadvances.com)
  • We tested the hypothesis that individuals with ESRD due to sickle cell disease (SCD-ESRD) receiving pre-ESRD care have lower mortality compared to individuals without pre-ESRD care. (cdc.gov)
Experimental1
  • In 1983, the US National Institutes of Health established, by consensus, that LT was to be considered out of the experimental realm and was to be clinically accepted as definitive therapy for end-stage liver disease (ESLD). (medscape.com)
Findings1
  • Presents findings from a test of the Million Hearts model for CMS through a large, randomized trial, including hundreds of thousands of beneficiaries across the United States of the Million Hearts model from 2017 to 2021. (rand.org)
Development2
  • It can be also used to visualize the embryological development of mice in uterus or to examine their cardiovascular development. (hindawi.com)
  • In this paper, we describe our coronary stent (INC-1) design and development, the way that we found the specific characteristics needed for our device including biophysics aspects, design, finite element testing, manufacturing, and mechanic trials, we submitted and animal models experiences. (scielo.org.mx)
Research1
  • This report was prepared by Eastern Research Group, Inc. (ERG), a contractor to the Agency for Toxic Substances and Disease Registry (ATSDR), as a general record of discussion for the expert panel review meeting on the Vieques Heart Study. (cdc.gov)
Management1
Methods2
  • Extracting these models from CT scans is done using statistical-probabilistic methods based on image processing. (sharif.edu)
  • In this study, new methods for extracting the 3D pore network model from 2D/3D CT scan images and pore connection detection are presented. (sharif.edu)
Registry2
  • This website is provided by the Agency for Toxic Substances and Disease Registry (ATSDR) ONLY as an historical reference for the public health community. (cdc.gov)
  • The Department, in turn, referred this request to the Agency for Toxic Substances and Disease Registry (ATSDR), which was already investigating environmental public health issues in Vieques. (cdc.gov)
Journal1
High-risk1
  • Discussion: Our study successfully detected and confirmed cataracts in a targeted, underserved urban population at high risk for eye disease. (cdc.gov)
Cases3
  • Worldwide, 5.4 million new cases of cardiovascular diseases are diagnosed, most of them related to coronary artery atherosclerosis, and cause more than half a million deaths annually and an economic expenditure of billions of dollars 1 . (scielo.org.mx)
  • It uses a graph attention network to capture spatio-temporal trends of disease dynamics and to predict the number of cases for a fixed number of days into the future. (nsf.gov)
  • In every forecast across 32 countries, the ensemble outperformed most contributing models when forecasting either cases or deaths, frequently outperforming all of its individual component models. (nsf.gov)
Status1
  • By combining information from real-world claims data and disease case counts data, STAN can better predict disease status and medical resource utilization. (nsf.gov)
Adults1
Performance1
  • We measured the performance of each model using the relative Weighted Interval Score (WIS), comparing models' forecast accuracy relative to all other models. (nsf.gov)