Mitotic drug targets. Medical search. Frequent questions

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Anatomy5

Cell Line, Tumor Cell Line HEK293 Cells Cells, Cultured HeLa Cells

Organisms29

Trypanosoma brucei brucei Mycobacterium tuberculosis Plasmodium falciparum Parasites Setaria Nematode Leishmania major Dictyocaulus Brugia malayi Life Cycle Stages Organisms, Genetically Modified Plasmodium Trypanosoma Schistosoma mansoni Mycobacterium smegmatis Plasmodium berghei Apicomplexa Escherichia coli Trypanosoma cruzi Leishmania mexicana Mice, Knockout Candida albicans Bacteria Mice, Inbred C57BL Schistosoma japonicum Toxoplasma Saccharomyces cerevisiae Aspergillus fumigatus Giardia lamblia Plasmodium vivax

Diseases6

Trypanosomiasis, African Neoplasms Trypanosomiasis Disease Disease Models, Animal Drug-Related Side Effects and Adverse Reactions

Chemicals and Drugs76

Pharmaceutical Preparations Small Molecule Libraries Protozoan Proteins Enzyme Inhibitors Antiprotozoal Agents Trypanocidal Agents Ligands Receptors, G-Protein-Coupled Bacterial Proteins Antineoplastic Agents Proteome Antiparasitic Agents Amide Synthases Auranofin Antimalarials Protein Kinase Inhibitors Proteins Isocoumarins Antitubercular Agents Anti-Bacterial Agents Helminth Proteins Recombinant Proteins RNA, Small Interfering Antifungal Agents Fusidic Acid Protease Inhibitors HSP90 Heat-Shock Proteins Anthelmintics Methenyltetrahydrofolate Cyclohydrolase Schistosomicides Nicotinamide-Nucleotide Adenylyltransferase Sterol 14-Demethylase Folic Acid Antagonists Pyrimidines Pyridoxal Kinase Peptides Cysteine Proteases Histamine H3 Antagonists Protein-Serine-Threonine Kinases Multienzyme Complexes Peroxisome Proliferator-Activated Receptors Aurora Kinases Aspartic Acid Endopeptidases Drugs, Investigational Benzamides Aurora Kinase B Antiviral Agents UDPglucose 4-Epimerase Spermidine Synthase Enzymes Enoyl-(Acyl-Carrier-Protein) Reductase (NADH)Enzyme Activators Protein Kinases Peptide Hydrolases Tetrahydrofolate Dehydrogenase Neoplasm Proteins Phosphotransferases (Alcohol Group Acceptor)Membrane Proteins Phenyl Ethers Polyamines Leucyl Aminopeptidase Peptide Library Oxidoreductases Azoles Viral Nonstructural Proteins Receptors, Histamine Amidohydrolases NADH, NADPH Oxidoreductases Amyloid Precursor Protein Secretases Protein Tyrosine Phosphatase, Non-Receptor Type 1 Topoisomerase II Inhibitors RNA Helicases RNA, Messenger Intramolecular Transferases Mutant Proteins Molecular Probes

Analytical, Diagnostic and Therapeutic Techniques and Equipment44

Drug Discovery Drug Design Drug Delivery Systems Drug Repositioning Molecular Targeted Therapy Drug Evaluation, Preclinical Models, Molecular Crystallography, X-Ray High-Throughput Screening Assays Gene Expression Profiling Protein Interaction Mapping Inhibitory Concentration 50 Models, Biological Sequence Alignment Gene Knockdown Techniques Cluster Analysis Molecular Docking Simulation Oligonucleotide Array Sequence Analysis Parasitic Sensitivity Tests Disease Models, Animal Drug Therapy Molecular Dynamics Simulation Cloning, Molecular Gene Knockout Techniques Combinatorial Chemistry Techniques Reproducibility of Results Technology, Pharmaceutical Mass Spectrometry Models, Chemical Protein Array Analysis Drug Approval Reverse Transcriptase Polymerase Chain Reaction Sequence Analysis, Protein Individualized Medicine Chemistry Techniques, Synthetic Drug Screening Assays, Antitumor Blotting, Western Microbial Sensitivity Tests Crystallization Models, Genetic Molecular Sequence Annotation Genetic Complementation Test Microarray Analysis Nuclear Magnetic Resonance, Biomolecular

Phenomena and Processes77

Genes, Essential Metabolic Networks and Pathways Amino Acid Sequence Molecular Structure Signal Transduction Protein Binding Binding Sites Catalytic Domain Protein Structure, Tertiary Protein Interaction Maps Pharmacological Processes Inhibitory Concentration 50 Structure-Activity Relationship Mutation Protein Conformation RNA Interference Substrate Specificity Sequence Homology, Amino Acid Life Cycle Stages Genome, Protozoan Structural Homology, Protein Algorithms Biosynthetic Pathways Kinetics Host-Pathogen Interactions Gene Regulatory Networks Phenotype Genes, Protozoan Cell Proliferation Allosteric Regulation Quantitative Structure-Activity Relationship Protein Structure, Secondary Molecular Dynamics Simulation Gene Expression Regulation Protein Interaction Domains and Motifs Phylogeny Gene Deletion Molecular Conformation Combinatorial Chemistry Techniques Gene Expression Gene Expression Regulation, Neoplastic Biocatalysis Genome, Bacterial Apoptosis Drug Resistance Protein Multimerization Genome, Helminth Proteolysis Genome, Human Protein Structure, Quaternary Drug Resistance, Neoplasm Dose-Response Relationship, Drug Chemistry Techniques, Synthetic Cell Survival Metabolism Catalysis Phosphorylation Amino Acid Motifs Protein Transport Drug Resistance, Fungal Genes, Helminth Transcriptome Microbial Viability Base Sequence Peptide Library Hydrogen Bonding Gene Library Species Specificity Dimerization Enzyme Activation Sequence Homology Allosteric Site Crystallization Conserved Sequence Protein Stability Genome Hydrophobic and Hydrophilic Interactions

Disciplines and Occupations12

Drug Discovery Drug Design Computational Biology Pharmacogenetics Systems Biology Proteomics Genomics Pharmacology Technology, Pharmaceutical Chemistry, Pharmaceutical Individualized Medicine Metabolomics

Anthropology, Education, Sociology and Social Phenomena1

Technology, Industry, Agriculture3

Combinatorial Chemistry Techniques Technology, Pharmaceutical Chemistry Techniques, Synthetic

Information Science21

Molecular Sequence Data Amino Acid Sequence Databases, Chemical Biological Ontologies Databases, Protein Databases, Pharmaceutical Crowdsourcing Algorithms Computer Simulation Molecular Docking Simulation Databases, Genetic Databases, Factual Data Mining Software Molecular Dynamics Simulation Phylogeny Internet Knowledge Bases User-Computer Interface Base Sequence Molecular Sequence Annotation

Health Care2

Cluster Analysis Reproducibility of Results

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Disciplines and Occupations Anthropology, Education, Sociology and Social Phenomena Technology, Industry, Agriculture Information Science Health Care

Drug Discovery Drug Design Drug Delivery Systems Drug Repositioning Molecular Targeted Therapy Drug Evaluation, Preclinical Pharmaceutical Preparations Models, Molecular Genes, Essential Computational Biology Trypanosoma brucei brucei Metabolic Networks and Pathways Crystallography, X-Ray Small Molecule Libraries Protozoan Proteins Enzyme Inhibitors High-Throughput Screening Assays Molecular Sequence Data Trypanosomiasis, African Antiprotozoal Agents Pharmacogenetics Amino Acid Sequence Molecular Structure Mycobacterium tuberculosis Plasmodium falciparum Signal Transduction Protein Binding Trypanocidal Agents Ligands Binding Sites Systems Biology Catalytic Domain Receptors, G-Protein-Coupled Gene Expression Profiling Protein Interaction Mapping Protein Structure, Tertiary Protein Interaction Maps Neoplasms Pharmacological Processes Inhibitory Concentration 50 Structure-Activity Relationship Parasites Bacterial Proteins Antineoplastic Agents Models, Biological Proteome Antiparasitic Agents Amide Synthases Proteomics Genomics Mutation Protein Conformation Auranofin Cell Line, Tumor RNA Interference Setaria Nematode Leishmania major Antimalarials Protein Kinase Inhibitors Proteins Databases, Chemical Substrate Specificity Biological Ontologies Databases, Protein Sequence Homology, Amino Acid Dictyocaulus Brugia malayi Pharmacology Databases, Pharmaceutical Crowdsourcing Life Cycle Stages Trypanosomiasis Genome, Protozoan Isocoumarins Sequence Alignment Structural Homology, Protein Algorithms Organisms, Genetically Modified Antitubercular Agents Plasmodium Disease Anti-Bacterial Agents Helminth Proteins Computer Simulation Recombinant Proteins Trypanosoma Schistosoma mansoni Gene Knockdown Techniques Biosynthetic Pathways Cluster Analysis Kinetics Molecular Docking Simulation Oligonucleotide Array Sequence Analysis Parasitic Sensitivity Tests Host-Pathogen Interactions Databases, Genetic Mycobacterium smegmatis RNA, Small Interfering Gene Regulatory Networks Phenotype

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