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  • cDNA
  • E05 478 566 350 170 or Enzyme-Linked Immunosorbent Assays,E05 478 566 350 170 or Enzyme-Linked Immunosorbent Assays,Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. (gentaur.com)
  • regulator
  • May function as a regulator of vesicle transport, through interactions with the JNK-signaling components and motor proteins. (nih.gov)
  • Regulator of G-Protein Signaling 19 (RGS19) and Its Partner Gα-Inhibiting Activity Polypeptide 3 (GNAI3) Are Required for zVAD-Induced Autophagy and Cell Death in L929 Cells. (ptglab.com)
  • Compound
  • From high throughput screening, we discovered compound 1, the prototype for a series of disubstituted thiophene inhibitors of JNK which is selective towards closely related MAP kinases p38 and Erk2. (rcsb.org)
  • Compound 61 demonstrated JNK3 IC(50)=77 nM and retained the excellent broad kinase selectivity observed for the series. (rcsb.org)
  • islet
  • Role of the JNK-interacting protein 1/islet brain 1 in cell degeneration in Alzheimer disease and diabetes. (nih.gov)
  • Calcium- and proteasome-dependent degradation of the JNK scaffold protein islet-brain 1. (nih.gov)
  • biochemical
  • MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. (abnova.com)
  • interactions
  • MAPK8IP2 has direct interactions with proteins and molecules. (creativebiomart.net)
  • Interactions are determined by geometric criteria as described in K. Stierand, M. Rarey (2010), Drawing the PDB: Protein-ligand complexes in two dimensions, ACS Med. (rcsb.org)
  • The pathway maps illustrate protein interactions and regulation to provide a comprehensive picture of signaling and disease processes. (bio-rad.com)
  • functions
  • This protein also functions as a DNA-binding transactivator of the glucose transporter GLUT2. (nih.gov)
  • Functions as an anti-apoptotic protein and whose level seems to influence the beta-cell death or survival response. (nih.gov)
  • Peptide
  • ACFP is an anti-cancer fusion peptide derived from bovine milk protein. (biomedcentral.com)
  • Peptide therapeutics represents an emerging field of anti-cancer agents that are easily obtained from either natural resources or are designed based on target protein structure. (biomedcentral.com)
  • genes
  • The JNK interacting protein JIP-1 and insulin like growth factor II genes are co-expressed in human embryonic tumours. (nih.gov)
  • It's important to note that these "pain variability genes" represent a subset of all "pain genes," defined simply as genes coding for proteins of relevance to pain. (mcgill.ca)
  • sequence
  • Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed. (uniprot.org)
  • section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. (uniprot.org)