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  • ERK2
  • Quantitative sandwich enzyme immunoassay (EIA) systems, that can distinguish between active-form subtypes of mitogen-activated protein kinases (p44 and p42 MAP kinase, also called ERK1 and ERK2), were developed employing subtype-specific antibodies as a solid phase and an antibody specific for the phosphorylated region of MAP kinases as the detector. (biomedsearch.com)
  • Both ERK1 and ERK2 were activated immediately after stimulation, and the activity reached a maximum at 5-10 min. (biomedsearch.com)
  • MKP-3 also binds to ERK2 regardless of whether it is phosphorylated or not. (wikipedia.org)
  • receptor
  • Hepatocyte growth factor/scatter factor (HGF/SF) is a mesenchymally derived signal that acts through the c- met receptor as a morphogen and mitogen for epithelial cells 1 and hepatocytes 2 and is implicated in both developmental and adult processes. (ahajournals.org)
  • This protein is a ligand for the EGF receptor. (wikipedia.org)
  • It is the sole known ligand for death receptor 3, and it can also be recognized by decoy receptor 3. (wikipedia.org)
  • This cytokine is a ligand for receptor TNFRSF25 (death receptor 3) and TNFRSF6B (decoy receptor 3). (wikipedia.org)
  • Constitutive
  • Substitution of a valine for a glutamic acid in the transmembrane domain can result in the constitutive dimerisation of this protein in the absence of a ligand. (wikipedia.org)