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  • partial
  • Unfortunately, current technological limitations of sequencers require that the cDNA molecules represent only partial fragments of the RNA being probed. (biomedcentral.com)
  • Proteins
  • This process requires the correct integration of 80 proteins, 1 mt (mitochondrial)-tRNA and 2 mt-rRNA species, the latter being post-transcriptionally modified at many sites. (biochemj.org)
  • species
  • In contrast, the 33273 bp (excluding the repeat region) piece of the mitochondrial genome that has been sequenced in both Euplotes species exhibits no difference in gene order. (biomedcentral.com)
  • Mitochondrial genetic mutations that occur in the nuclear DNA can occur in any of the chromosomes (depending on the species). (wikipedia.org)
  • Mitochondrial ribosomes differ between species [ 3 , 8 - 11 ] but for mammalian mitoribosome assembly, as with the eubacterial system, the number of key assembly factors is likely to be few [ 12 - 17 ]. (biochemj.org)
  • protein
  • The central dogma of molecular biology "the flow of genomic information from DNA to RNA to protein" in multi-cellular organisms is much more complex than originally thought [ 1 ]. (pubmedcentralcanada.ca)
  • Fragmentation
  • Most protocols also include a fragmentation step, typically RNA hydrolysis or nebulization, or alternatively cDNA fragmentation by DNase I treatment or sonication. (biomedcentral.com)
  • fragments
  • The biochemistry of RNA-Seq library preparation results in cDNA fragments that are not uniformly distributed within the transcripts they represent. (biomedcentral.com)
  • The randomness inherent in many of the preparation steps for RNA-Seq leads to fragments whose starting points (relative to the transcripts from which they were sequenced) appear to be chosen approximately uniformly at random. (biomedcentral.com)
  • generalized conformational behavior of intercalation complexes with RNA and DNA fragments. (uni-trier.de)
  • maturation
  • Evidence for the role of double-helical structures in the maturation of simian virus-40 messenger RNA. (uni-trier.de)
  • interactions
  • The main research focus is on regulation of RNA editing and its interactions with the system of translation. (ucr.edu)
  • transcript
  • Using Brain RNA sample from multiple runs, we demonstrated that the transcript profiles from 3' DGE were highly reproducible between technical and biological replicates from libraries constructed by the same lab and even by different labs, and between two generations of Illumina's Genome Analyzers. (biomedcentral.com)
  • However
  • However, mitochondrial lineages from Africa, south Asia, central Asia, and the Middle East, which altogether contribute the vast majority of imported malaria cases in the United States, were closely related to each other and could not be reliably assigned to their geographic origins. (ajtmh.org)
  • However, if a male has a mitochondrial trait, no offspring inherit it. (wikipedia.org)