Reactive Oxygen SpeciesOxygenMitochondriaOxidative StressApoptosisCell DeathCytochromes cCaspasesHydrogen PeroxideMembrane Potential, MitochondrialAntioxidantsNADPH OxidaseProto-Oncogene Proteins c-bcl-2bcl-2-Associated X ProteinCaspase 3Apoptosis Inducing FactorSignal TransductionFree Radical ScavengersCells, CulturedBongkrekic AcidCaspase 9Superoxide DismutaseOxygen ConsumptionMitochondria, HeartMitochondrial Membrane Transport ProteinsOxidation-ReductionCatalaseCytochrome c GroupAcetylcysteineCell SurvivalSuperoxidesEnzyme ActivationCause of DeathOxidantsbcl-2 Homologous Antagonist-Killer ProteinCell Line, TumorMyocytes, CardiacCaspase 8bcl-X ProteinGlutathioneRats, Sprague-DawleyLipid PeroxidationOnium CompoundsReactive Nitrogen SpeciesSinglet OxygenXanthine OxidaseTumor Suppressor Protein p53Cyclic N-OxidesMembrane PotentialsFree RadicalsMembrane ProteinsNitric OxideDeathHydroxyl RadicalProto-Oncogene ProteinsDNA DamageEnzyme InhibitorsTime FactorsDose-Response Relationship, DrugCell LineGlutathione PeroxidaseRotenoneMice, Inbred C57BLBlotting, WesternAscorbic AcidMitochondrial Proteins1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium SaltVitamin K 3Luminescent MeasurementsAcetophenonesRespiratory BurstXanthineModels, BiologicalMice, KnockoutOxygen Inhalation TherapyDNA FragmentationAnoxiaCell HypoxiaElectron Transport Complex IMetalloporphyrinsPeroxiredoxinsPhosphorylationNeutrophilsEndothelium, VascularRNA, MessengerNF-kappa BUp-RegulationDisease Models, AnimalProtein CarbonylationDeoxyguanosineCell RespirationParaquatElectron TransportCytoprotectionNF-E2-Related Factor 2Spin LabelsMalondialdehydeGene Expression RegulationRats, Wistarp38 Mitogen-Activated Protein Kinases