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Mitochondrial Proton-Translocating ATPasesMitochondrial MembranesMitochondriaMitochondrial ProteinsProtonsMicroscopy, ElectronTrityl CompoundsMicroscopy, Electron, TransmissionMitochondria, MuscleMitochondria, LiverIon ChannelsOxygen ConsumptionOligomycinsOxidative PhosphorylationPhosphate-Binding ProteinsProton PumpsCell RespirationUncoupling AgentsIntracellular MembranesMembrane Transport ProteinsAdenosine TriphosphateEnergy MetabolismCarrier ProteinsProton-Translocating ATPasesMembrane PotentialsAdipose Tissue, BrownAdenosine TriphosphatasesMuscle, SkeletalKineticsCalcium-Transporting ATPasesSemicircular DuctsVacuolar Proton-Translocating ATPasesProteinsProton Pump InhibitorsHair Cells, VestibularHydrogen-Ion ConcentrationMagnetic Resonance SpectroscopyOrganelle ShapeCaesalpiniaMolecular Sequence DataSemicircular CanalsAmino Acid SequenceProton-Motive ForceMitochondrial SizeEar, InnerCell MembraneModels, MolecularPlasma Membrane Calcium-Transporting ATPasesVacuolesEthmoid BoneMutationElectron Transport Complex IVH(+)-K(+)-Exchanging ATPaseCation Transport ProteinsSaccharomyces cerevisiaeAtrial Function, RightVestibule, Labyrinth
DysfunctionMatrixMembraneInner mitochonCardiacAssociateComplexes
Dysfunction1
  • Mitochondria have been implicated in several human disorders and conditions, such as mitochondrial diseases, cardiac dysfunction, heart failure and autism. (wikipedia.org)
Matrix1
  • Because of this double-membraned organization, there are five distinct parts to a mitochondrion: The outer mitochondrial membrane, The intermembrane space (the space between the outer and inner membranes), The inner mitochondrial membrane, The cristae space (formed by infoldings of the inner membrane), and The matrix (space within the inner membrane), which is a fluid. (wikipedia.org)
Membrane2
  • The outer mitochondrial membrane, which encloses the entire organelle, is 60 to 75 angstroms (Å) thick. (wikipedia.org)
  • The outer mitochondrial membrane can associate with the endoplasmic reticulum (ER) membrane, in a structure called MAM (mitochondria-associated ER-membrane). (wikipedia.org)
Inner mitochon2
  • This double membrane-bound organelle generates most adenosine triphosphate (ATP) through OXPHOS, processed by ETC embedded in the inner mitochondrial membrane (IMM). (frontiersin.org)
  • Because of this double-membraned organization, there are five distinct parts to a mitochondrion: The outer mitochondrial membrane, The intermembrane space (the space between the outer and inner membranes), The inner mitochondrial membrane, The cristae space (formed by infoldings of the inner membrane), and The matrix (space within the inner membrane), which is a fluid. (wikipedia.org)
Cardiac1
  • Mitochondria have been implicated in several human disorders and conditions, such as mitochondrial diseases, cardiac dysfunction, heart failure and autism. (wikipedia.org)
Associate1
  • The outer mitochondrial membrane can associate with the endoplasmic reticulum (ER) membrane, in a structure called MAM (mitochondria-associated ER-membrane). (wikipedia.org)
Complexes1
  • Mitochondrial pro-proteins are imported through specialised translocation complexes. (wikipedia.org)