Adaptor Proteins, Signal TransducingAdaptor Proteins, Vesicular TransportAdaptor Protein Complex 2Adaptor Protein Complex 1GRB2 Adaptor ProteinAdaptor Protein Complex 3Shc Signaling Adaptor ProteinsAdaptor Protein Complex alpha SubunitsAdaptor Protein Complex beta SubunitsAdaptor Protein Complex mu SubunitsAdaptor Protein Complex gamma SubunitsGRB10 Adaptor Proteinsrc Homology DomainsClathrinSignal TransductionProtein BindingMyeloid Differentiation Factor 88PhosphoproteinsAdaptor Protein Complex delta SubunitsProto-Oncogene Proteins c-crkCarrier ProteinsProtein Structure, TertiaryMolecular Sequence DataAmino Acid SequencePhosphorylationCRADD Signaling Adaptor ProteinProteinsMembrane ProteinsClathrin-Coated VesiclesAdaptor Protein Complex 4EndocytosisCell LineGRB7 Adaptor ProteinProtein TransportAdaptor Protein Complex SubunitsMonomeric Clathrin Assembly ProteinsAmino Acid MotifsTyrosineCARD Signaling Adaptor Proteinstrans-Golgi NetworkIntracellular Signaling Peptides and ProteinsTwo-Hybrid System TechniquesMice, KnockoutEndosomesRecombinant Fusion ProteinsAdaptor Protein Complex sigma SubunitsCoated Pits, Cell-MembraneBinding SitesReceptors, Interleukin-1Jurkat CellsToll-Like ReceptorsMutationImmunoprecipitationCOS CellsProto-Oncogene Proteins c-cblOncogene ProteinsToll-Like Receptor 4HeLa CellsCytoskeletal ProteinsTransfectionHEK293 CellsCrk-Associated Substrate ProteinSequence Homology, Amino AcidFas-Associated Death Domain ProteinProtein-Tyrosine KinasesCoated VesiclesNerve Tissue ProteinsMice, Inbred C57BLPrecipitin TestsCullin ProteinsCells, CulturedCell MembraneModels, BiologicalNuclear ProteinsProtein Interaction Domains and MotifsEnzyme ActivationPhosphotyrosineMembrane GlycoproteinsUbiquitin-Protein Ligasessrc-Family KinasesPhospholipase C gammaTNF Receptor-Associated Factor 6Receptors, Antigen, T-CellVesicular Transport ProteinsSon of Sevenless ProteinsRNA, Small InterferingUbiquitinationUbiquitinADP-Ribosylation FactorsImmunoblottingToll-Like Receptor 3Receptors, ImmunologicCytoplasmProto-Oncogene ProteinsZAP-70 Protein-Tyrosine KinaseInterferon Regulatory Factor-3Multiprotein ComplexesT-LymphocytesPaxillinProtein-Serine-Threonine Kinases