AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesAnthropology, Education, Sociology and Social PhenomenaInformation ScienceGeographicals
MisoprostolAbortifacient Agents, NonsteroidalOxytocicsAdministration, IntravaginalAdministration, SublingualAbortifacient Agents, SteroidalAbortion, InducedVacuum CurettagePostpartum HemorrhageAbortion, IncompleteCervical RipeningMifepristoneAbortifacient AgentsPregnancy Trimester, FirstDilatation and CurettageUterine HemorrhageLabor, InducedPregnancyDilatationHysteroscopyAlprostadilLabor Stage, ThirdAnti-Ulcer AgentsOxytocinAdministration, OralAdministration, BuccalCervix UteriAnti-Inflammatory Agents, Non-SteroidalProstaglandins E, SyntheticDiclofenacEndometritisAbortion, MissedMedicine, Tibetan TraditionalPregnancy Trimester, SecondMauritaniaClostridium sordelliiErgonovineHome ChildbirthMenstruation-Inducing AgentsNonprescription DrugsEncyclopedias as TopicStomach UlcerAbortion, Spontaneous
MifepristoneAbortionsMiscarriageCytotecContractionsPregnancyIntravaginal misoprostolFailed to induce laborPregnanciesExpelAccess to misoprostolMedicationProstaglandinDrugsDosePillsComplicationVaginallyDrugGestational AgeCesareanCervicalCervixWomenTablet was placedVaginal deliveryLaborComplicationsMedicalMenstrualPostpartumLabourMethodsEffectiveSymptomsPillClinicalSafelyProtocolsAdministrationTongue
Mifepristone37
  • The World Health Organization (WHO) has endorsed two regimens for abortion up to 12 weeks of pregnancy using misoprostol: a standardized regimen of mifepristone and misoprostol and a regimen of misoprostol alone. (wikipedia.org)
  • The regimen with misoprostol alone has been shown to be up to 83% effective in terminating a pregnancy but is more effective combined with mifepristone. (wikipedia.org)
  • The only scientifically studied effective self-induced abortion method is ingesting a combination of mifepristone and misoprostol or misoprostol alone. (wikipedia.org)
  • Some women use online abortion pill help services such as Women on Web and Aid Access to order mifepristone and/or misoprostol, with reported effectiveness and safety in pregnancy termination and satisfaction in the service. (wikipedia.org)
  • Our aim was to summarize extant data on the effectiveness and safety of regimens using the widely recommended lower mifepristone dose, 200 mg, followed by misoprostol in early pregnancy and to explore potential correlates of abortion failure. (nih.gov)
  • To identify eligible reports, we searched Medline, reviewed reference lists of published reports, and contacted experts to identify all prospective trials of any design of medical abortion using 200 mg mifepristone followed by misoprostol in women with viable pregnancies up to 63 days' gestation. (nih.gov)
  • 8 weeks, the specified interval between mifepristone and misoprostol was less than 24 h, the total misoprostol dose was 400 mcg (rather than higher), or the misoprostol was administered by the oral route (rather than by vaginal, buccal, or sublingual routes). (nih.gov)
  • Early medical abortion with mifepristone 200 mg followed by misoprostol is highly effective and safe. (nih.gov)
  • It is essential that countries register misoprostol and mifepristone on national drug registries, and ensure their laws comply with the World Health Organization's (WHO) guidance on the broad range of healthcare providers who can administer abortion care. (reproductiverights.org)
  • In Safe Abortion: Technical and Policy Guidance for Health Systems , the World Health Organization (WHO) states that misoprostol and mifepristone, the medicines taken to induce an abortion, are essential medicines every State that legally permits medical abortion must have available and accessible to women. (reproductiverights.org)
  • Medical abortion consists of two prescription-only medications: mifepristone and misoprostol taken up to 48 hours apart. (healthnews.com)
  • The two drugs involved are mifepristone (also called Mifeprex) and misoprostol. (catholicnewsagency.com)
  • Chemical abortions can be reversed after a woman takes mifepristone, but before she takes misoprostol - although this action must be taken quickly. (catholicnewsagency.com)
  • To have a medication abortion, patients typically take mifepristone to kill the fetus followed by misoprostol to induce labor. (wnd.com)
  • A medical abortion involves taking medication (usually Mifepristone or Misoprostol) to induce an early miscarriage. (dane101.com)
  • Risks of mifepristone and misoprostol, the most common abortion drugs taken together to abort and then expel an unborn baby from the womb, include excessive bleeding, severe abdominal pain, infection, hemorrhage and death. (lifenews.com)
  • Mifepristone, which the FDA first approved in 2000, is taken in combination with Misoprostol to induce a safe abortion. (ca.gov)
  • Apparently, Health Canada has been considering approval of mifepristone (known as RU-486) since December 2012," as "the drug is considered the gold standard for inducing safe and early non-surgical abortion. (jillstanek.com)
  • Prosecutors were also never able to substantiate their claim about self-induced abortion because there were no traces of misoprostol and mifepristone in Patel's blood. (salon.com)
  • Early medical abortion will be defined in this presentation by termination of pregnancies with Mifepristone/Misoprostol when no visible gestational sac is visible on ultrasound. (fiapac.org)
  • Early medical abortion using mifepristone and misoprostol requires less provider involvement, is highly effective and can largely be managed by women themselves. (fiapac.org)
  • Early medical abortion with misoprostol is a safe and effective regimen and is recommended by the World Health Organization in settings without access to mifepristone. (ourbodiesourselves.org)
  • The envelope contained the human pesticides, mifepristone and misoprostol: two drugs used to induce abortion at home. (nationalrighttolifenews.org)
  • She praised technology's growing potential to provide women and girls with chemical abortion drugs, mifepristone and misoprostol even in states where abortion is illegal. (nationalrighttolifenews.org)
  • A person's ability to self-administer mifepristone and misoprostol after receiving instructions from a provider is well established, and there is evidence that it is safe and effective for someone to do so without the direct supervision of a provider. (wholewomanshealth.com)
  • Mifepristone (Mifeprex) and Misoprostol, the two drugs used in a medication abortion, are seen at the Women's Reproductive Clinic, which provides legal medication abortion services, in Santa Teresa, New Mexico, on June 17, 2022. (businessinsider.in)
  • Mifepristone is taken first to stop the pregnancy, followed by Misoprostol to induce bleeding. (businessinsider.in)
  • In other contexts, both mifepristone and misoprostol are used to voluntarily terminate pregnancies, and both medications are often called 'abortion pills. (yahoo.com)
  • But while misoprostol is indicated for a wide range of medical uses, including labor induction and ulcer treatment, mifepristone is taken almost exclusively to induce abortions and manage miscarriages, the latter of which is an off-label use. (yahoo.com)
  • Since 2018, the American College of Obstetricians and Gynecologists (ACOG) has recommended a two-drug protocol of mifepristone and misoprostol for patients who elect the medication route. (yahoo.com)
  • It is still illegal to perform an abortion in Texas, including by dispensing or mailing the abortion-inducing medications mifepristone and misoprostol, in most circumstances. (texastribune.org)
  • Abortion medication: A federal judge in Amarillo revoked the Food and Drug Administration's approval of mifepristone - an abortion-inducing medication - after a lawsuit by a group of anti-abortion doctors. (texastribune.org)
  • Subsequently, medical options that interfere with the progesterone support (mifepristone) and induce uterine contractions (misoprostol) became available. (medscape.com)
  • The review summarizes the findings of six randomized controlled trials (RCTs) and nine prospective observational studies of mifepristone and misoprostol use for medical abortion. (medscape.com)
  • There is considerable heterogeneity with respect to the dose of mifepristone (50 mg-600 mg) or misoprostol (200 µg-800 µg) used and the route of misoprostol administration (oral, buccal, vaginal). (medscape.com)
  • The investigators concluded that mifepristone and misoprostol provide effective medical abortion for very early pregnancies (up to 42 days). (medscape.com)
  • Medical management of abortion generally involves either a combination regimen of mifepristone and misoprostol or a misoprostol-only regimen. (bvsalud.org)
Abortions22
  • Although the term includes abortions induced outside of a clinical setting with legal, sometimes over-the-counter medication, it also refers to efforts to terminate a pregnancy through alternative, potentially more dangerous methods. (wikipedia.org)
  • In Latin America, women have reported self-inducing abortions with misoprostol alone since the 1980s. (wikipedia.org)
  • Self-induced abortions can be safe or unsafe depending on the methods used. (wikipedia.org)
  • It is difficult to measure the prevalence or rate of self-induced abortions. (wikipedia.org)
  • As of 2018[update], in the United States, the estimate was that one in 10 abortions is self-induced. (wikipedia.org)
  • In 1969, CDC began abortion surveillance to document the number and characteristics of women obtaining legal induced abortions, to monitor unintended pregnancy, and to assist efforts to identify and reduce preventable causes of morbidity and mortality associated with abortions. (cdc.gov)
  • This report summarizes and reviews information reported to CDC regarding legal induced abortions obtained in the United States in 1996. (cdc.gov)
  • The abortion ratio was 314 legal induced abortions per 1,000 live births, and as in 1995, the abortion rate was 20 per 1,000 women aged 15-44 years. (cdc.gov)
  • In 1992, the case-fatality rate of legal induced abortion was 0.7 abortion-related deaths per 100,000 legal induced abortions. (cdc.gov)
  • As in previous years, deaths related to legal induced abortions occurred rarely (i.e., approximately one death per 100,000 legal induced abortions). (cdc.gov)
  • The number and characteristics of women who obtain abortions in the United States should continue to be monitored so that trends in induced abortion can be assessed, efforts to prevent unintended pregnancy can be evaluated, and the preventable causes of morbidity and mortality associated with abortions can be identified and reduced. (cdc.gov)
  • Bankole A, Singh S, Haas T. Reasons why women have induced abortions: evidence from 27 countries. (medigraphic.com)
  • Despite the fact that abortion-inducing drugs are four times more fatal than surgical abortions, we continue to see the administration's push for their expansion … with little to no safeguards. (lifenews.com)
  • Since then, more than 5 million women have used it, along with another drug, misoprostol, to induce abortions. (whnt.com)
  • One complication here is that one of the abortion pills, misoprostol, has legitimate medical uses other than inducing abortions. (electoral-vote.com)
  • The group filmed themselves crossing the border to buy Misoprostol , an ulcer drug that is used off-label to induce abortions. (jillstanek.com)
  • Misoprostol is available only by prescription in the U.S. and can only be dispensed by doctors for abortions. (jillstanek.com)
  • The mortality rate related to induced abortion was 0.6 deaths per 100,000 abortions. (medscape.com)
  • Two articles published last week have noted a surge in self-induced abortions (DIY abortions), each looking at a different low access area in the Gulf. (truthout.org)
  • According to the Atlantic , the surge of pregnant people turning to misoprostol is in many ways a flashback to the Latin American and Hispanic, Catholic-dominated countries where because abortion is illegal in all circumstances, women and girls were forced to secretly induce abortions as their own response to unwanted fertility. (truthout.org)
  • It works almost as well as misoprostol, but it is very expensive and not used for abortions for this reason alone. (medscape.com)
  • PROBLEM/CONDITION: CDC conducts abortion surveillance to document the number and characteristics of women obtaining legal induced abortions and number of abortion-related deaths in the United States. (cdc.gov)
Miscarriage7
  • A self-induced abortion (also called a self-managed abortion, or sometimes a self-induced miscarriage) is an abortion performed by the pregnant woman herself, or with the help of other, non-medical assistance. (wikipedia.org)
  • misoprostol induces a miscarriage. (cbc.ca)
  • An Arizona woman needed a drug to induce a miscarriage. (vox.com)
  • The medicines induce an abortion that resembles a miscarriage. (womenonweb.org)
  • Based on estimated lifetime risk, each American woman is expected to have 3.2 pregnancies, of which 2 will be a live birth, 0.7 will be an induced abortion, and 0.5 will be a miscarriage. (medscape.com)
  • Also known as miso or Cytotec, the drug induces an abortion that appears like a miscarriage during the early stages of a woman's pregnancy. (now.org)
  • While misoprostol also is a safe and effective treatment on its own, physicians stress, it is markedly less effective than the two-drug combination - requiring follow-up surgery to complete the miscarriage in roughly 1 in 4 cases. (yahoo.com)
Cytotec6
Contractions6
Pregnancy11
  • Self-induced (or self-managed) abortion is often attempted during the beginning of pregnancy (the first eight weeks from the last menstrual period). (wikipedia.org)
  • Misoprostol still works after 12 weeks of pregnancy. (womenonwaves.org)
  • Legal induced abortion was defined as a procedure, performed by a licensed physician or someone acting under the supervision of a licensed physician, that was intended to terminate a suspected or known intrauterine pregnancy and to produce a nonviable fetus at any gestational age (1,2). (cdc.gov)
  • therefore, labour should only be induced when the risk of allowing the continuation of pregnancy outweighs the risk of induction. (hindawi.com)
  • Consequences for women are not negligible: repeated consultations, repeated ultrasound, repeated HCG could delay the termination of the pregnancy and induce problems of costs, confidentiality or emotional distress. (fiapac.org)
  • And while misoprostol is unquestionably a safe method to self-induce abortion, women may use a variety of less effective and more dangerous methods to end a pregnancy on their own, including taking herbs or self-inflicting abdominal trauma. (ourbodiesourselves.org)
  • Administration of misoprostol is an effective clinical method to terminate second trimester, complicated pregnancy. (who.int)
  • In Dar es Salaam misoprostol can be accessed clandestinely for pregnancy termination through drug stores or health facilities offering different levels of safety and costs. (fiapac.org)
  • Pregnancy should be confirmed before abortion is induced. (msdmanuals.com)
  • They can be used to induce abortion between 13-20 weeks of pregnancy. (medscape.com)
  • Because most women will expel the pregnancy within 2-24 hr of taking misoprostol, discuss with the patient an appropriate location for her to be when she takes the misoprostol. (medscape.com)
Intravaginal misoprostol4
  • To compare the efficacy and safety of intravaginal misoprostol with transcervical Foley catheter for labour induction. (hindawi.com)
  • Intravaginal misoprostol is associated with a shorter induction to delivery interval as compared to Foley's catheter and it increases the rate of vaginal delivery in cases of unripe cervix at term. (hindawi.com)
  • Upon hemodynamic and respiratory improvement, we decided to induce labor with intravaginal misoprostol after consulting with the obstetricians on the third day after admission. (hindawi.com)
  • ABSTRACT To assess the effectiveness of intravaginal misoprostol for second trimester uterine evacuation, we studied 70 women with singleton pregnancies complicated by fetal malformation or dead fetuses. (who.int)
Failed to induce labor1
Pregnancies3
  • The aim of this project was to enhance knowledge about the challenges faced by young women with unwanted pregnancies living in an urban, low-income settings where abortion is criminalised but assumed to be performed clandestinely with increasing off-label use of the recently registered drug misoprostol. (fiapac.org)
  • CONCLUSIONS: As women seek to terminate unwanted pregnancies in legally restrictive settings, online sales of misoprostol must be considered. (bvsalud.org)
  • Medical abortion care encompasses the management of various clinical conditions including spontaneous and induced abortion (both viable and non-viable pregnancies), incomplete abortion and intrauterine fetal demise, as well as post-abortion contraception. (bvsalud.org)
Expel2
  • Misoprostol induces labor, causing a woman's body to expel the baby. (ortl.org)
  • This is followed by misoprostol to expel the tissue. (yahoo.com)
Access to misoprostol2
  • The confluence of extremely limited access to abortion in the context of poverty, access to misoprostol from Mexico, as well as familiarity with the practice of self-induction in Latin America, makes it particularly likely that self-induction will become more commonplace in Texas. (ourbodiesourselves.org)
  • So as to understand online access to misoprostol, we created a protocol to identify the most visible universe of sellers. (bvsalud.org)
Medication2
Prostaglandin4
  • Misoprostol oral tablets contain either 100 mcg or 200 mcg of misoprostol, a synthetic prostaglandin E1 analog. (nih.gov)
  • The results of the present study revealed that ketamine treatment induced NF‑κB p65 translocation to nuclei and activated COX‑2 expression and prostaglandin (PGE)2 production in bladder tissue, whereas COX‑2 inhibitor suppressed the inflammatory effect. (spandidos-publications.com)
  • The most common methods of labour induction when the status of cervix is unfavourable involve intravaginal use of misoprostol, transcervical insertion of Foley's catheter, and insertion of prostaglandin gel whereas with a ripe cervix oxytocin may be administered intravenously. (hindawi.com)
  • Misoprostol is a synthetic prostaglan- women had a 5-MHz transducer sono- din, structurally related to prostaglandin graphic examination. (who.int)
Drugs4
  • Drug interaction studies between misoprostol and several nonsteroidal anti-inflammatory drugs showed no effect on the kinetics of ibuprofen or diclofenac, and a 20% decrease in aspirin AUC, not thought to be clinically significant. (nih.gov)
  • Yet the high cost, waiting periods and fear of those who are outside the clinic doors trying to harass them as they go in all combine to make some women just prefer to seek out the drugs and try to induce an abortion quietly and privately, out of the public eye, in their own time and with less expense involved. (truthout.org)
  • Brick and mortar pharmacies, a common place to purchase misoprostol off-label in other parts of the world, are monitored closely by the government authority in Indonesia which controls drugs so that they cannot function outside the law without risking arrest and prosecution. (bvsalud.org)
  • The interaction progressed to purchasing misoprostol with 76 sellers, 64 of whom sent drugs. (bvsalud.org)
Dose4
  • I took the first dose of Misoprostol and started bleeding. (womenonwaves.org)
  • Misoprostol was more effective than placebo in healing small bowel ulcers in patients who used daily low-dose aspirin. (the-hospitalist.org)
  • There is high variability of plasma levels of misoprostol acid between and within studies but mean values after single doses show a linear relationship with dose over the range of 200 to 400 mcg. (nih.gov)
  • Maximum plasma concentrations of misoprostol acid are diminished when the dose is taken with food and total availability of misoprostol acid is reduced by use of concomitant antacid. (nih.gov)
Pills4
Complication2
Vaginally2
  • Misoprostol can be administered orally, sublingually or vaginally. (fiapac.org)
  • When administered to achieve cervical ripening misoprostol can be administered sublingually, only one hour prior to surgery, or if preferred vaginally with 3 hours interval. (fiapac.org)
Drug6
  • has received both oral and written warnings of the hazards of Misoprostol Tablets, the risk of possible contraception failure, and the danger to other women of childbearing potential should the drug be taken by mistake. (nih.gov)
  • The second drug, misoprostol, is taken up to two days later, and induces labor. (catholicnewsagency.com)
  • Typically, women also are prescribed a second drug, misoprostol, that induces labor and expels their aborted baby's body. (lifenews.com)
  • Instead, her doctor prescribed a drug called misoprostol, which on its own is less effective. (yahoo.com)
  • The two-drug combination is just as safe as misoprostol alone. (yahoo.com)
  • Background: Disseminated Intravascular coagulopathy (DIC) has been reported following use of Misoprostol which is an old drug with new indications in Obstetrics and Gynecology. (bvsalud.org)
Gestational Age1
Cesarean2
  • Using misoprostol in the second trimester also increases the risk of hemorrhage that might require surgical intervention or transfusion, as well as the risk of uterine rupture if inappropriately high dosages are used, especially with a history of prior cesarean delivery. (ourbodiesourselves.org)
  • There is some association with uterine rupture when using misoprostol for labor induction in patients with prior cesarean section so it should be used with caution. (medscape.com)
Cervical2
Cervix4
  • Kvinnen fikk tabletter med 25 µg misoprostol peroralt, da det mislyktes å legge inn ballongkateter i cervix. (tidsskriftet.no)
  • Such a catheter appears to induce labour not only through direct mechanical dilation of the cervix but also by stimulating endogenous release of prostaglandins. (hindawi.com)
  • Misoprostol induces a softening, 'priming' effect on the cervix making mechanical dilatation less difficult. (fiapac.org)
  • In a study by Singh of primigravid women (6-11 wk gestation), 93.3% achieved dilatation of the cervix of 8 mm or greater after 3 h of postintravaginal misoprostol at 400 mcg, whereas only 16.7% of women achieved this after 2 h at 600 mcg. (medscape.com)
Women11
  • Women can use many different methods to self-manage (or self-induce) an abortion. (wikipedia.org)
  • Misoprostol Tablets should not be used for reducing the risk of NSAID-induced ulcers in women of childbearing potential unless the patient is at high risk of complications from gastric ulcers associated with use of the NSAID, or is at high risk of developing gastric ulceration. (nih.gov)
  • In 1992, 10 women died as a result of complications from legal induced abortion, and no deaths were reported associated with illegal abortion. (cdc.gov)
  • In the case of women who have previously undergone a caesarean section and thereby run an increased risk for uterine rupture in connection with vaginal delivery, induction of labour with misoprostol may further enhance this risk and is not recommended. (hindawi.com)
  • A protocol for follow up of early medical abortion will be presented based on correct information given to the women (especially symptoms that must induce a visit to the emergency service) and serum HCG testing seven days after the medical abortion. (fiapac.org)
  • Misoprostol reduces the rate of complications after surgical abortion when administered as a medical priming agent prior to vacuum aspiration, both in nulliparous and parous women. (fiapac.org)
  • Misoprostol is also used in non-pregnant women to facilitate IUS insertion or dilatation prior to hysteroscopy. (fiapac.org)
  • Misoprostol and herbs were the methods women more commonly mentioned. (ourbodiesourselves.org)
  • To induce abortion is viewed as a common practice by young women in Dar es Salaam. (fiapac.org)
  • METHODS: We carried out a mystery client methodology to replicate the experiences of women procuring misoprostol online. (bvsalud.org)
  • New evidence submitted to the Committee showed that misoprostol can be safely administered to women to prevent postpartum haemorrhage by traditional birth attendants or assistants trained to use the product at home deliveries. (who.int)
Tablet was placed2
Vaginal delivery1
  • The rate of vaginal delivery was 76.7% versus 56.8% in misoprostol and transcervical Foley catheter group, respectively. (hindawi.com)
Labor2
  • Misoprostol is easier to find locally as it is registered in many countries for stomach ulcers, inducing labor, or for treating postpartum hemorrhages. (artech.se)
  • Also, inducing labor? (artech.se)
Complications1
  • Many health workers experience fewer and more manageable complications among their postabortion care patients related to misoprostol use for abortion. (fiapac.org)
Medical1
  • Studies confirm a correlation between the increase in the self-administration of medical abortion with misoprostol, and a reduction in maternal morbidity and mortality. (wikipedia.org)
Menstrual2
  • If you have prolonged bleeding, too much bleeding (much more than a regular menstrual period), pain in your belly that does not go away after a few days of taking the Misoprostol, pain that is unbearable, fever, continued bleeding after three weeks, or pain when pushing on your belly, you may have an incomplete abortion. (womenonwaves.org)
  • will begin Misoprostol Tablets only on the second or third day of the next normal menstrual period. (nih.gov)
Postpartum1
  • The Committee added misoprostol tablet (200 µg) for the prevention of postpartum haemorrhage, where oxytocin is not available or cannot be safely used. (who.int)
Labour3
  • thus there has been increasing interest in misoprostol for use as a pharmacological agent for labour induction. (hindawi.com)
  • The aim of this study is the comparison of vaginal misoprostol and transcervical Foley's catheter for induction of labour. (hindawi.com)
  • Method: This is to report a case of disseminated intravascular coagulopathy (DIC) associated with use of misoprostol for induction of labour and to call for extra vigilance in its use.Result: This was a case of 22-year old gravida 2 para 1 at 42 weeks gestation that was induced with 100?g of isoprostol and delivered a live female baby with good Apgar score. (bvsalud.org)
Methods2
  • Self-induced abortion methods vary around the world. (wikipedia.org)
  • Induced abortion is considered safe when WHO recommended methods are used by trained persons, less safe when only one of those two criteria is met, and least safe when neither is met. (wikipedia.org)
Effective1
Symptoms2
  • How long will it take before Misoprostol will have effect and for how long will symptoms (bellyache, nausea, blood loss etc.) last? (womenonwaves.org)
  • The symptoms and signs of ketamine-induced ulcerative cystitis (KIC) include increased voiding frequency, non-voiding contraction, hematuria and dysuria. (spandidos-publications.com)
Pill3
Clinical1
  • Misoprostol is extensively absorbed, and undergoes rapid de-esterification to its free acid, which is responsible for its clinical activity and, unlike the parent compound, is detectable in plasma. (nih.gov)
Safely1
Protocols1
  • You can find more information on misoprostol-only protocols from the WHO at www.who.int/health-topics/abortion . (wholewomanshealth.com)
Administration3
  • In normal volunteers, misoprostol is rapidly absorbed after oral administration with a T max of misoprostol acid of 12 ± 3 minutes and a terminal half-life of 20 to 40 minutes. (nih.gov)
  • After oral administration of radiolabeled misoprostol, about 80% of detected radioactivity appears in urine. (nih.gov)
  • However, there remains some controversy concerning the dosage, the mode, and interval of administration of misoprostol. (hindawi.com)
Tongue1