• Misoprostol is used for the prevention of NSAID-induced gastric ulcers. (wikipedia.org)
  • Because other classes of drugs, especially H2-receptor antagonists and proton pump inhibitors, are more effective for the treatment of acute peptic ulcers, misoprostol is only indicated for use by people who are both taking NSAIDs and are at high risk for NSAID-induced ulcers, including the elderly and people with ulcer complications. (wikipedia.org)
  • However, even in the treatment of NSAID-induced ulcers, omeprazole proved to be at least as effective as misoprostol, but was significantly better tolerated, so misoprostol should not be considered a first-line treatment. (wikipedia.org)
  • In the US, Misoprostol (misoprostol systemic) is a member of the drug class miscellaneous GI agents and is used to treat Abortion , Cervical Ripening , Duodenal Ulcer , Gynecological Conditions , Labor Induction , NSAID-Induced Ulcer Prophylaxis , Postpartum Bleeding and Stomach Ulcer . (drugs.com)
  • Misoprostol reduces stomach acid and helps protect the stomach from damage that can be caused by taking a nonsteroidal anti-inflammatory drug (NSAID) such as aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others. (healthbanks.com)
  • Misoprostol is used to prevent stomach ulcers during treatment with aspirin or an NSAID. (healthbanks.com)
  • It is not inherently unsafe if medically supervised, but 1% of women will have heavy bleeding requiring medical attention, some women may have ectopic pregnancy, and the 12% of pregnancies that continue after misoprostol failure are more likely to have birth defects and are usually followed up with a more effective method of abortion. (wikipedia.org)
  • Misoprostol can also be used to dilate the cervix in preparation for a surgical abortion, particularly in the second trimester (either alone or in combination with laminaria stents). (wikipedia.org)
  • A review of the recent literature on misoprostol shows that it successfully completes expulsion in approximately 66-99% of women who receive it for incomplete, inevitable, and missed abortion in the first trimester (4-12). (acog.org)
  • Specifically, one extensive review found median success was 80% or higher for missed abortion and 92% for incomplete abortion treated with misoprostol (15). (acog.org)
  • Misoprostol may be more successful at treating women experiencing an incomplete abortion compared with a missed abortion (12, 14). (acog.org)
  • The fact that misoprostol is also misused in Pakistan - and other developing countries like Brazil - to induce abortion cheaply, has added to controversies over the drug. (ipsnews.net)
  • In October 2017, the Chief Medical Officer and Health Secretary in Scotland recognised a woman's home as a safe and acceptable place to take misoprostol, the second drug used to effect an early medical abortion. (rcog.org.uk)
  • Today, the Cabinet Secretary for Health and Social Services in Wales has announced an agreement to allow misoprostol at home for medical abortion treatment. (rcog.org.uk)
  • In England, women who have an early medical abortion are forced to return to the clinic to take misoprostol. (rcog.org.uk)
  • This Patient Information Sheet is for pregnant women who may receive misoprostol to soften their cervix or induce contractions to begin labor. (fda.gov)
  • What should I discuss with my healthcare provider before taking misoprostol? (healthbanks.com)
  • Doctors like Ahsan are dismayed at moves to get WHO to reverse its listing in April 2011 of misoprostol among essential medicines that "satisfy the healthcare needs of the majority of the population" and are "available at all times in adequate amounts and in appropriate dosage forms, at a price the community can afford. (ipsnews.net)
  • Misoprostol reduces the cost of postabortion care services because it does not require the immediate availability of sterilized equipment, operating theatres, or skilled personnel (2). (acog.org)
  • Administration of misoprostol or another uterotonic (a drug that reduces bleeding after childbirth) could prevent the majority of these deaths. (msh.org)
  • A formulation for preparing Misoprostol 1-mg Suppository. (ijpc.com)
  • A formulation for preparing Misoprostol 0.0027% Mucoadhesive Powder. (ijpc.com)
  • What other drugs will affect misoprostol? (uwhealth.org)
  • Other drugs may interact with misoprostol, including prescription and over-the-counter medicines, vitamins, and herbal products. (uwhealth.org)
  • WHO guidelines advocate the use of misoprostol against PPH, while the International Federation of Gynaecology and Obstetrics (FIGO) suggests using the drug in situations where regular 'uterotonic' drugs like oxytocin and ergometrine are not available. (ipsnews.net)
  • Do not use misoprostol if you are pregnant. (healthbanks.com)
  • You should not use this medicine if you are allergic to misoprostol or other prostaglandins, or if you are pregnant. (healthbanks.com)
  • Upon the birth attendant's arrival, Linda presented the three misoprostol pills she had recently been given by a home health promoter. (msh.org)
  • Several days prior, a home health promoter had visited Linda and discussed with her a birth preparedness plan, informing her of the benefits of taking misoprostol immediately after delivery to prevent excessive bleeding. (msh.org)
  • Unlike other uterotonics, misoprostol has the advantage that it does not need refrigeration for storage and can be easily administered orally by trained birth attendants, Ahsan said. (ipsnews.net)
  • Do have it taped the above cloud-based antibiotics re the coupled anent nurseries me obtained in misoprostol medicine for the list doses they coop big arteritis. (upsoft.pl)
  • There is increasing evidence that misoprostol is a safe, effective, and acceptable method to achieve uterine evacuation for women needing postabortion care. (acog.org)
  • Allyson Pollock, who led the study, stated that there is insufficient evidence to suggest that misoprostol works in preventing PPH. (ipsnews.net)
  • However, for the purposes of meeting the urgent needs of women, particularly in rural, underserved communities, we are confident about being guided by the abundant literature and expert evidence supporting the safety and effectiveness of misoprostol for multiple reproductive health indications," de Silva said. (ipsnews.net)
  • Evidence suggests that misoprostol is safe, and allowing women to take it at home is a question of patient safety, as it would prevent women from having to deal with the effects of the medication on their way from a clinic. (rcog.org.uk)
  • Misoprostol is sometimes used to decrease blood loss after delivery of a baby. (fda.gov)
  • Misoprostol is also used to decrease the toxic effects to the kidney resulting from the use of cyclosporine. (heartlandvetsupply.com)
  • Misoprostol may also be used for purposes not listed in this medication guide. (healthbanks.com)
  • Although studies show a range of efficacy, higher success has been achieved when clinicians wait for 1-2 weeks after misoprostol treatment before judging success or failure (11, 13, 15). (acog.org)
  • No company has sent the FDA scientific proof that misoprostol is safe and effective for these uses. (fda.gov)
  • Misoprostol is promising and we should do our best to evaluate its safe use," said Bhutta. (ipsnews.net)
  • The use of misoprostol at home is safe and is endorsed by the World Health Organization. (rcog.org.uk)