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  • replication
  • The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. (acris-antibodies.com)
  • The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression.The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. (acris-antibodies.com)
  • Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. (string-db.org)
  • RefSeq
  • The several alternatively spliced sequence databases now publicly available differ in their annotation and modeling methods and contain many transcripts not present in reference resources like Ensembl or Refseq ( 3 ). (aacrjournals.org)
  • CCND3
  • Jim DeCaprio ( james_decaprio@dfci.harvard.edu ) suggested adding cyclin D2 (CCND2) and 3 (CCND3) in addition to Cyclin D1 (CCND1) as MAPK targets. (cancer.gov)
  • Human
  • Our approach provides a framework for examining molecular signatures of disease in fibrosis and autoimmune diseases and for leveraging publicly available data to understand common and tissue-specific disease processes in complex human diseases. (biomedcentral.com)