AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPsychiatry and PsychologyPhenomena and ProcessesDisciplines and OccupationsTechnology, Industry, AgricultureInformation ScienceHealth Care
Molecular MimicryBiomimetic MaterialsBiomimeticsMolecular Sequence DataModels, MolecularAmino Acid SequencePeptidesProtein BindingDisease Models, AnimalCells, CulturedBinding SitesCell LineKineticsMutationCrystallography, X-RayModels, BiologicalSignal TransductionPeptidomimeticsProtein Structure, TertiaryTime FactorsProtein ConformationMolecular StructureBase SequencePhosphorylationPeptide LibraryProtein Structure, SecondaryDrug DesignStructure-Activity RelationshipMice, Inbred C57BLMicroRNAsRecombinant ProteinsDose-Response Relationship, DrugRats, Sprague-DawleyPeptoidsCell Line, TumorAntibodies, Anti-IdiotypicGene Expression RegulationPredatory BehaviorOligopeptidesTissue EngineeringRNA, MessengerSubstrate SpecificityPeptide FragmentsPhenotypeLigandsEnzyme InhibitorsMetalloporphyrinsMolecular ConformationMice, TransgenicEscherichia coliTransfectionCalciumCell ProliferationTranscription FactorsRabbitsCell DifferentiationAntibodies, MonoclonalEnzyme ActivationMagnetic Resonance SpectroscopyCell Culture TechniquesCatalytic DomainDNABacterial ProteinsMice, Inbred BALB CBinding, CompetitiveNeuronsCell MembraneApoptosisCatalysisRecombinant Fusion ProteinsEpitopesCattleImmunohistochemistryMutagenesis, Site-DirectedDNA-Binding ProteinsHydrogelsMembrane ProteinsComputer SimulationBlotting, WesternCell SurvivalNuclear Magnetic Resonance, BiomolecularProteinsTranscription, GeneticMice, KnockoutDNA PrimersSequence Homology, Amino AcidModels, ChemicalProtein EngineeringHydrogen BondingCarrier ProteinsCell AdhesionOxidation-ReductionGene ExpressionPolymersAmino Acid SubstitutionReverse Transcriptase Polymerase Chain ReactionBiocompatible MaterialsRats, WistarCircular DichroismBrain
Medical Information Mart for Intensive CarePharmacologicalMetastaticLesionPortfoliosNonspecificBehaviorClinicalDiagnosisResearchersConstraintsCreatureSyntheticCloselyRecognizeEffectsCloseMakeRealDataCreatePatientBroadUpdateModelCritical careApproachHumanAuthorWriteBabyDrugSenseFlexibleDesignVersionProblemPreviousConditionsWorkSaveFoundLead
Medical Information Mart for Intensive Care2
  • MIMIC-III ('Medical Information Mart for Intensive Care') is a large, single-center database comprising information relating to patients admitted to critical care units at a large tertiary care hospital. (nature.com)
  • The Medical Information Mart for Intensive Care (MIMIC)-III database provided critical care data for over 40,000 patients admitted to intensive care units at the Beth Israel Deaconess Medical Center (BIDMC). (physionet.org)
Pharmacological1
  • The pharmacological mimics of GLP-1 can also have these effects in the body. (merriam-webster.com)
Metastatic2
  • Malignant melanoma is one of medicine's imitators, and metastatic disease can mimic cysts. (hindawi.com)
  • Osseous sarcoidosis is an uncommon manifestation of sarcoidosis that can mimic metastatic bone disease on imaging. (cmaj.ca)
Lesion2
  • The purpose of this paper is to report a case of DA mimicking a periapical lesion. (bvsalud.org)
  • the case suggests that thiamine deficiency presumably causes mitochondrial dysfunction with cerebrospinal fluid lactic acidosis and a stroke -like lesion mimicking MELAS syndrome . (bvsalud.org)
Portfolios2
  • We'll present the application of reinforcement learning to create factor-mimicking portfolios. (nvidia.com)
  • We'll discuss alternatives to derive factor-mimicking portfolios with multi-period constraints using a model free reinforcement-learning approach. (nvidia.com)
Nonspecific2
  • Early signs and symptoms of these illnesses are nonspecific or mimic other illnesses, which can make diagnosis challenging. (cdc.gov)
  • The clinical patterns of adverse drug reactions of the oral cavity include xerostomia, swelling, nonspecific ulceration, vesiculobullous or ulcerative mucositis that mimics other disease states, nonspecific vesiculoulcerative mucositis, pigmentation, gingival enlargement, and medication-related osteonecrosis of the jaws. (medscape.com)
Behavior1
  • The researchers find that this behavior mimics that of disordered systems driven by external forces, such as ferromagnetic materials subjected to magnetic fields or amorphous materials subjected to a shearing force. (aps.org)
Clinical6
  • MIMIC-III integrates deidentified, comprehensive clinical data of patients admitted to the Beth Israel Deaconess Medical Center in Boston, Massachusetts, and makes it widely accessible to researchers internationally under a data use agreement ( Fig. 1 ). (nature.com)
  • MIMIC-III has been integral in driving large amounts of research in clinical informatics, epidemiology, and machine learning. (physionet.org)
  • This database is a subset of the MIMIC-III Waveform Database , representing those records for which the patient has been identified, and their corresponding clinical records are available in the MIMIC-III Clinical Database . (physionet.org)
  • Collecting this broad clinical context is the task of the MIMIC-III Clinical Database , which was created in parallel with the Waveform Database and contains information about many of the same patients. (physionet.org)
  • It is more accurate than physical examination and has influenced clinical practice and patient care by eliminating unnecessary diagnostic arthroscopies or by identifying an alternative diagnosis whose clinical presentation may mimic meniscal tears. (medscape.com)
  • These adverse drug reactions have a broad spectrum of clinical manifestations that can mimic those of other disease states, including both local and systemic conditions. (medscape.com)
Diagnosis1
  • We report a case involving differential diagnosis of syphilitic bilateral papillitis mimicking papilloedema. (cdc.gov)
Researchers4
  • 2023 The situation is so dire that one startup has created mimics of the mRNA vaccines in use to help researchers improve their formulations. (merriam-webster.com)
  • In partnership with a group at the University of California San Diego (UCSD) in the United States, the researchers for the first time created cortical organoids that mimic focal cortical dysplasia and identified mechanisms that may be involved in the emergence of the anomaly during brain formation. (eurekalert.org)
  • Now, researchers have developed a new method that mimics how baby dragonflies ready their jelly-like wings for flight. (newscientist.com)
  • Researchers at the University of Utah are working on using peptide mimics as drug target surrogates to develop new treatments for Ebola. (genengnews.com)
Constraints1
  • 2023 The advantage of this approach, where only the boundaries have actuators, is that the system is easier to control and build than systems that more precisely mimic biology, and the mechanical constraints make the cascading dominoes easy to apply to different scales. (merriam-webster.com)
Creature1
  • Ashley Lee, Los Angeles Times , 26 May 2023 Instead of masquerading as a dangerous creature, an aggressive mimic poses as one that's benign. (merriam-webster.com)
Synthetic2
  • Ryan Faughnder, Los Angeles Times , 27 June 2023 The evolution of synthetic biology has allowed such companies to create mimics of the real thing, such as methyl jasmonate-a fragrance that evokes the same tea-like, moon-blooming scent of white jasmine petals-as well as a musk alternative that eliminates the need to source from animals. (merriam-webster.com)
  • Then, we use these characterizations to generate new synthetic data that mimics the real one in many aspects of compression. (usenix.org)
Closely4
  • The rise of generative AI has created tools that more closely mimic patient care. (merriam-webster.com)
  • Through paced bottle-feeding, you may be able to closely mimic nursing. (healthline.com)
  • Paced bottle-feeding aims to slow feedings to closely mimic breast-feeding. (healthline.com)
  • You can also switch the sides that your baby is held on, which can more closely mimic breast-feeding. (healthline.com)
Recognize1
  • Furthermore, it is important to recognize MS mimics to initiate appropriate treatment for those conditions. (medscape.com)
Effects2
  • A bacterial genome's evolution under changing drug concentrations displays effects of memory formation and mimics how disordered solids respond to external forces. (aps.org)
  • that is, BPA may mimic some of the hormone-like effects of estrogen. (cdc.gov)
Close1
  • mimic implies a close copying (as of voice or mannerism) often for fun, ridicule, or lifelike imitation. (merriam-webster.com)
Make2
  • copy , imitate , mimic , ape , mock mean to make something so that it resembles an existing thing. (merriam-webster.com)
  • The problem is that these apps that mimic a real world interface make for pretty terrible computing interfaces. (brooksreview.net)
Real2
  • Austa Somvichian-Clausen, Robb Report , 11 June 2023 Several important features of real embryos are present in the mimics , the team says, including the predecessors of sperm and eggs and the beginnings of the amnion, the membrane-like structure that encloses the embryo in a watery environment. (merriam-webster.com)
  • Marisa Sloan, Discover Magazine , 15 Mar. 2023 Graham Taylor, who started Helix Biotech last year, says labs have shown that their mimics trigger similar immune responses to the real McCoy. (merriam-webster.com)
Data6
  • Here we report the release of the MIMIC-III database, an update to the widely-used MIMIC-II database ( Data Citation 1 ). (nature.com)
  • MIMIC-III contains data associated with 53,423 distinct hospital admissions for adult patients (aged 16 years or above) admitted to critical care units between 2001 and 2012. (nature.com)
  • Here we present MIMIC-IV, an update to MIMIC-III, which incorporates contemporary data and improves on numerous aspects of MIMIC-III. (physionet.org)
  • MIMIC-IV adopts a modular approach to data organization, highlighting data provenance and facilitating both individual and combined use of disparate data sources. (physionet.org)
  • Through this library, testers can mimic user interactions to applications such as clicking or typing to verify composer's (controller layer) data and logic. (zkoss.org)
  • To address this problem, we propose a benchmarking methodology called mimicking and apply it in the domain of data compression. (usenix.org)
Create1
  • Create an account below to get 6 C&EN articles per month, receive newsletters and more - all free. (acs.org)
Patient3
  • Table 1 Details of the MIMIC-III patient population by first critical care unit on hospital admission for patients aged 16 years and above. (nature.com)
  • Importantly, MIMIC-III was deidentified, and patient identifiers were removed according to the Health Insurance Portability and Accountability Act (HIPAA) Safe Harbor provision. (physionet.org)
  • The MIMIC-III Waveform Database contains thousands of recordings of multiple physiologic signals ("waveforms") and time series of vital signs ("numerics") collected from bedside patient monitors in adult and neonatal intensive care units ( ICUs ). (physionet.org)
Broad1
  • MIMIC-IV is intended to carry on the success of MIMIC-III and support a broad set of applications within healthcare. (physionet.org)
Update1
  • Had some internet issues over the last few weeks(hate you telstra) so heres a update on the mimic. (cgsociety.org)
Model2
  • Byjon Cohen, science.org , 30 May 2023 The result is essentially a two-tier business model where lonely guys looking for a 3 a.m. chat session can talk with Marjorie's machine mimic , while die-hard fans willing to shell out a bit more can pay for the genuine article. (merriam-webster.com)
  • In sum, our model mimics what we see in patients and can be used in future to screen existing medications," Iscia Lopes-Cendes , a professor at UNICAMP's Medical School and penultimate author of the paper, told Agência FAPESP . (eurekalert.org)
Critical care1
  • Figure 1: Overview of the MIMIC-III critical care database. (nature.com)
Approach1
  • The use of peptide mimics as drug targets played a key role in the development of treatments for HIV, and we believe this approach can be applied to the treatment of Ebola," pointed out Dr. Kay, who added that the team relied on a peptide synthesizer from Tucson-based Protein Technologies to carry out the research. (genengnews.com)
Human1
Author1
  • article{64d88d5f-8005-40b8-a78d-138d8661f21c, author = {{Dejmek, Annika}}, issn = {{0001-5547}}, language = {{eng}}, number = {{6}}, pages = {{1059--1062}}, publisher = {{Karger}}, series = {{Acta Cytologica}}, title = {{Fine needle aspiration cytology of an ovarian luteinized follicular cyst mimicking a granulosa cell tumor. (lu.se)
Write1
  • Elizabeth Kolbert, The New Yorker , 27 Mar. 2023 ChatGPT was unveiled to the public in November and was quickly taken up by millions of users impressed with its ability to clearly answer difficult questions, mimic writing styles, write sonnets and papers and even pass exams. (merriam-webster.com)
Baby1
  • By mimicking the pattern and flow of breast-feeding, a baby is more likely to be able to switch between breast and bottle, if desired. (healthline.com)
Drug1
  • This peptide mimic can be used as a target to identify new drug treatments to control the Ebola virus, according to the investigators. (genengnews.com)
Sense1
  • IEEE Spectrum , 16 Nov. 2021 So these drugs in a sense mimic , at least to some degree, an eating disorder. (merriam-webster.com)
Flexible1
  • Counterfeiters are extremely flexible in the methods they use to mimic products and prevent their detection. (who.int)
Design2
  • The Prelude system enabled us to quickly design and optimize the synthesis of the peptide mimics of the ebolavirus N-trimer," he said. (genengnews.com)
  • Ko mimicked these interlocked bumps in his sensor design through two layers of stretchy polydimethylsiloxane (PDMS) mixed with conductive carbon nanotubes. (scientificamerican.com)
Version2
Problem1
  • ZATS (ZK Application Test Suite) Mimic is designed to solve this kind of problem. (zkoss.org)
Previous1
  • Based on our experience with the previous major release of MIMIC (MIMIC-II, released in 2010) we anticipate MIMIC-III to be widely used internationally in areas such as academic and industrial research, quality improvement initiatives, and higher education coursework. (nature.com)
Conditions1
  • Which of the following medical conditions can be mimicked by cholinesterase inhibitor toxicity? (cdc.gov)
Work1
  • This agent can work on column , listheader , and treecol and mimic to sort a header with specified sorting order. (zkoss.org)
Save1
  • ACS's Standard Package lets you stay up to date with C&EN, stay active in ACS, and save. (acs.org)
Found1
  • Bymitch Leslie, science.org , 17 June 2023 Staters Of the coins found in Brandenburg, 19 are staters - mimics of the gold and silver coins found in ancient Greece. (merriam-webster.com)
Lead1