• Can people with mild to moderate dementia provide reliable answers about their quality of life? (bath.ac.uk)
  • However growing evidence suggests that people with mild to moderate dementia may be able to complete standardised questionnaire items and articulate feelings, providing reliable evaluations of their health and QoL. (bath.ac.uk)
  • Objective to examine the reliability of the item pool of a new measure of self-reported QoL, the Bath Assessment of Subjective Quality of Life in Dementia (BASQID) Subjects sixty people with mild to moderate dementia, recruited from a memory clinic. (bath.ac.uk)
  • The consistency of responses over a 2-week period suggests that self-reported QoL assessments are feasible and appropriate for people with mild to moderate dementia. (bath.ac.uk)
  • The present study examines the stability of the Word Accentuation Test - Buenos Aires version (TAP-BA) performance in patients with mild and moderate dementia, and disexecutive syndrome. (bvsalud.org)
  • Fifty-two participants, - 11 dementia patients with mild cognitive impairment (DcL), 11 dementia patients with moderate cognitive impairment (DcM), 17 participants with disexecutive syndrome (DEj), and 13 without cognitive impairment (CTR) paired by age, education and sex, completed a neuropsychological battery and the TAPBA. (bvsalud.org)
  • DAPA is a randomised controlled trial funded by the National Institute for Health Research Health Technology Assessment programme to estimate the effect of a 4-month, moderate- to hard-intensity exercise training programme and subsequent advice to remain active, on cognition (primary outcome) at 12 months in people with mild to moderate dementia. (biomedcentral.com)
  • Treatments for dementia recommended by the National Institute for Health and Care Excellence (NICE) [ 3 ] are cholinesterase inhibitors (donepezil, galantamine and rivastigmine), but only for mild to moderate Alzheimer's disease (not for vascular dementia). (biomedcentral.com)
  • Memantine is supported by NICE for limited use in moderate to severe dementia, or in patients unable to tolerate cholinesterase inhibitors [ 3 ]. (biomedcentral.com)
  • Many people with mild to moderate dementia and their families require additional services, mainly to mitigate functional loss, such as carer training, home carers, day care, respite admissions, sitting services and carer support services. (biomedcentral.com)
  • Also, few studies compared factors between severity types, often grouping moderate and severe infants together or comparing survivors and non-survivors. (scielo.org.za)
  • The effect of this novel product is independent from the severity of the symptoms unlike traditional antidepressants available on the market that have minimal benefits for subthreshold or mild-to-moderate symptoms. (psychiatrist.com)
  • Within this stressed plasma environment at moderate disease, multiple unusual immune cell phenotypes emerge and amplify with increasing disease severity. (metabolon.com)
  • The best treatment for mild to moderate sleep apnea depends on the severity of your problem, the structure of your upper airway, any medical problems you may have, and your personal preference. (bhdentists.com)
  • it is not always correctly identified, because most cases are mild, and the severity of tics decreases for most children as they pass through adolescence. (wikipedia.org)
  • It is currently FDA-approved for the treatment of adult patients with moderate-to-severe plaque psoriasis who are candidates for phototherapy or systemic therapy, adult patients with active psoriatic arthritis, and adults with oral ulcers associated with Behçet's Disease. (drugtopics.com)
  • The phase 3 ADVANCE study is a multicenter, randomized, placebo-controlled, double-blind trial that assessed the efficacy and safety of apremilast in adults with mild-to-moderate plaque psoriasis. (drugtopics.com)
  • Many patients with mild-to-moderate plaque psoriasis who use topical therapies still have challenges managing their psoriasis," David M. Reese, MD, executive vice president of Research and Development at Amgen, said in a statement. (drugtopics.com)
  • 1. Amgen Announces Positive Top-Line Results From Otezla® (apremilast) Phase 3 ADVANCE Study In Mild-To-Moderate Plaque Psoriasis. (drugtopics.com)
  • ORLANDO - A newly synthesized nonsteroidal anti-inflammatory drug, benvitimod, is a safe and effective topical treatment for mild to moderate plaque psoriasis , according to phase 3 trial results. (medscape.com)
  • This article shows some examples of what plaque psoriasis can look like and explains how to tell if you have a mild, moderate, or severe case. (healthline.com)
  • Is your plaque psoriasis mild, moderate, or severe? (healthline.com)
  • The purpose of this study is to identify and follow a population of mild to moderate aortic stenosis patient to assess the natural history of aortic stenosis in the 2010's. (mayo.edu)
  • Should patients with asymptomatic mild or moderate aortic stenosis undergoing coronary artery bypass surgery also have valve replacement for their aortic stenosis? (bmj.com)
  • PITTSBURG, PA, USA I November 08, 2018 I Cognition Therapeutics, Inc. , a clinical stage neuroscience company focused on synaptic protection and restoration in Alzheimer's disease and other neurodegenerative disorders, today announced that patient treatment has begun in the Phase 2 SHINE study of Elayta™ (CT1812), Cognition's lead candidate for the treatment of mild-to-moderate Alzheimer's disease. (pipelinereview.com)
  • SHINE ( S ynaptic H ealth and I mprovement of N eurological Function with E layta) is a randomized, double-blind, placebo-controlled, parallel-group Phase 2 efficacy and safety study designed to enroll up to 160 adults with mild-to-moderate Alzheimer's disease (MMSE 18-26). (pipelinereview.com)
  • Cognition's lead product candidate, Elayta (CT1812), a highly brain penetrant small molecule with a unique disease-modifying synaptorestorative mechanism of action, is currently in Phase 2 clinical testing for mild-to-moderate Alzheimer's disease. (pipelinereview.com)
  • This study will assess the effects of the experimental drug T3D-959 in people with mild to moderate Alzheimer's disease. (alzheimers.gov)
  • Cortiment®$^{MMX®}$ (budesonide MMX®) is currently approved for the induction of remission in mild-to-moderate ulcerative colitis (UC) patients when 5-ASA treatment is not sufficient. (uzh.ch)
  • The UC Diet appears to be effective for induction of remission in children with mild to moderate UC suggesting that diet could play a role in the disease. (ecco-ibd.eu)
  • Apremilast (Otezla, Amgen) significantly improved psoriasis symptoms compared with a placebo in adults with mild-to-moderate disease. (drugtopics.com)
  • We look forward to discussions with the FDA about the potential to bring Otezla, which has already been prescribed to hundreds of thousands of patients with moderate-to-severe psoriasis, to more patients who may need additional therapeutic options. (drugtopics.com)
  • Findings from the study highlight potential unmet needs had by patients with mild psoriasis seeking treatment. (drugtopics.com)
  • National report - The Food and Drug Administration has approved Vectical (Galderma), an ointment containing calcitriol, for the treatment of mild-to-moderate psoriasis, according to WebMD. (dermatologytimes.com)
  • Cite this: New Topical for Mild to Moderate Psoriasis in the Works - Medscape - Mar 05, 2017. (medscape.com)
  • The diagnosis was 'mild iron deficiency anemia,' and iron therapy was prescribed. (cdc.gov)
  • For patients with moderate symptoms, hospitalization is unlikely unless they are having difficulty drawing a breath or are dehydrated. (ijpr.org)
  • Headache and anosmia have been frequently described as neurological symptoms of mild-to-moderate COVID-19 but a direct impact of COVID-19 on neuronal integrity has not been clarified yet [ 4 ]. (springer.com)
  • All COVID-19 patients had mild-to-moderate symptoms and recovered after 1-3 weeks and showed no or only minor neurological symptoms, including anosmia and headache. (springer.com)
  • Supplementation of SAMe and L. plantarum HEAL9 in adults with subthreshold or mild-to-moderate symptoms of depression resulted in fast and clinically relevant effects after 2 weeks. (psychiatrist.com)
  • For example, the International Classification of Diseases , Tenth Revision ( ICD-10 ) 2 , 3 categorizes depressive episodes into different groups according to the number of symptoms present, distinguishing between mild, moderate, and severe depression. (psychiatrist.com)
  • In mild to moderate diverticulitis, localized symptoms are present without any evidence of perforation, abscess, or significant comorbidity. (medscape.com)
  • The symptoms of mild depression extend beyond feeling down temporarily. (depressionals.com)
  • The symptoms of moderate depression are more severe than mild depression. (depressionals.com)
  • Most moderate depressions are characterized by symptoms severe enough to affect daily life and livelihood. (depressionals.com)
  • The symptoms of moderate depression are more noticeable than those of mild depression because they significantly affect daily life. (depressionals.com)
  • Major depression occurs when mild depression and anxiety symptoms are combined into a more severe condition that is noticeable even to those closest to you. (depressionals.com)
  • Mild to moderate COVID-19 patients were managed with hydroxychloroquine (HQ) plus antibiotics (n = 31) or conservative treatment (n = 195). (medrxiv.org)
  • Use of salicylates and/or antibiotics can be effective in mild to moderate disease, while steroids are the accepted therapy for more severe active disease. (aafp.org)
  • According to the new report, "while most people with COVID-19 develop mild or uncomplicated illness, approximately 14% develop severe disease requiring hospitalization and oxygen support and 5% require admission to an intensive care unit to try to prevent the most severe complications including septic shock - a significant drop in blood pressure that can lead to stroke, heart or respiratory failure, failure of other organs or death. (ijpr.org)
  • In 80% of known cases, COVID-19 causes mild to moderate illness, according to a report of a joint World Health Organization-China mission of 25 infectious disease experts held in China late last month. (ijpr.org)
  • Our results indicate for the first time that COVID-19 may affect the neuro-axonal integrity also in adults with a mild-to-moderate course of the disease. (springer.com)
  • We identify a major shift between mild and moderate disease, at which point elevated inflammatory signaling is accompanied by the loss of specific classes of metabolites and metabolic processes. (metabolon.com)
  • This immune-response axis independently aligns with the major plasma composition changes, with clinical metrics of blood clotting, and with the sharp transition between mild and moderate disease. (metabolon.com)
  • This study suggests that moderate disease may provide the most effective setting for therapeutic intervention. (metabolon.com)
  • Researchers are assessing the safety and efficacy of fosgonimeton (ATH-1017) for the treatment of patients with mild to moderate Alzheimer disease in a phase 3 clinical trial. (psychiatryadvisor.com)
  • Researchers are conducting a phase 3 trial to evaluate the safety and efficacy of subcutaneously administered fosgonimeton by comparing high dose, low dose , and placebo treatment groups in patients with mild to moderate Alzheimer disease (AD). (psychiatryadvisor.com)
  • The FDA has also approved the oral antiviral nirmatrelvir with ritonavir (Paxlovid) for the treatment of mild-to-moderate COVID-19 in adults who are at high risk for progression to severe disease. (cdc.gov)
  • Infliximab, an antibody to human tumor necrosis factor alpha, has proved successful in the treatment of severe refractory disease and generally causes only mild side effects. (aafp.org)
  • Screening Tools for Sarcopenia in Mild to Moderate Parkinson's Disease: Assessing the Accuracy of SARC-F and Calf Circumference. (bvsalud.org)
  • ritonavir tablets) is a prescription oral antiviral drug that reduces the risk of hospitalization and death for patients with mild-to-moderate COVID-19 who are at risk of disease progression and severe il ness (1). (cdc.gov)
  • Of the patients reporting good adherence, a greater proportion of those with severe OSA (27%) than with mild or moderate disease (0%-12%) reported an excellent response to treatment. (cdc.gov)
  • Conclusions Recognition of a substantial potential for chronic problems after mild to moderate road traffic injury is essential to ensure that clinical management approaches and compensation schemes anticipate, minimize and address long-term problems, and detect potentially modifiable early targets for intervention. (bmj.com)
  • The clinical spectrum of SARS-CoV-2 infection includes asymptomatic or pre-symptomatic infection and mild, moderate, severe, and critical illness. (cdc.gov)
  • Information about clinical management and treatment of COVID-19 is stratified by whether the patient has mild or moderate illness that often can be managed in the outpatient setting, or severe or critical illness that requires hospitalization. (cdc.gov)
  • Persons at this stage manifest deficits which are subtle, but which are noted by persons who are closely associated with the person with mild cognitive impairment. (alzinfo.org)
  • For example, a person with mild cognitive impairment (MCl) may noticeably repeat queries. (alzinfo.org)
  • At a press conference on March 9, Maria Van Kerkhove , technical lead of the WHO Health Emergencies Program, said: "[A] mild infection starts normally with a fever, although it may take a couple of days to get a fever. (ijpr.org)
  • Twenty-eight adult patients with mild to moderate hypertension were randomly assigned to a double-blind treatment either with losartan 50 mg titrated to losartan 50 mg-hydrochlorothiazide 12.5 mg or amlodipine 5 mg titrated to amlodipine 10 mg. (karger.com)
  • Losartan significantly reduced QTd after 16 weeks of treatment in patients with mild to moderate hypertension. (karger.com)
  • If you have mild to moderate obstructive sleep apnea, an oral appliance may be a simple and effective treatment option. (bhdentists.com)
  • NSAIDs or paracetamol for short-term treatment of mild to moderate knee pain in early osteoarthritis: are they equivalent? (bmj.com)
  • To evaluate the effectiveness and response Gastric balloon (Lexbal) in the treatment of mild to moderate obesity Methods: We conducted in one clinic and hospital paroissien an observational, retrospective study. (alliedacademies.org)
  • To be eligible for this study, patients must be aged 55 to 85, diagnosed with mild to moderate AD , have a caregiver, cannot be receiving acetylcholinesterase inhibitor treatment (or has not been treated at least 4 weeks prior to screening), and have a body mass index (BMO) between 18 to 35 kg/m 2 . (psychiatryadvisor.com)
  • In addition, the FDA has issued an emergency use authorization (EUA) for the oral antiviral molnupiravir (Lagevrio), which can be used for treatment of patients with mild to moderate illness who are at risk for severe illness. (cdc.gov)
  • Mild depression may not require medical treatment, but it will not necessarily go away by itself. (depressionals.com)
  • This means that children with mild hearing impairment might not be detected until later in childhood, if at all," says Dr Lorna Halliday from the University of Cambridge. (neurosciencenews.com)
  • Detecting even mild degrees of hearing impairment earlier could lead to earlier intervention that would limit these brain changes, and improve children's chances of developing normal language. (neurosciencenews.com)
  • This results suggests that the test is not sensitive to moderate and mild impairment or to executive deficits, being useful for estimating premorbid cognitive functioning in Spanish-speaking patients. (bvsalud.org)
  • Most patients with COVID-19 experience asymptomatic or mild illness that does not warrant medical intervention, or mild to moderate illness that can be managed in the outpatient setting. (cdc.gov)
  • The present study suggests that mild-moderate exercise is not very harmful for SCA patients. (unboundmedicine.com)
  • Evidence Central , evidence.unboundmedicine.com/evidence/view/EBMG/453354/all/Mild_to_moderate_perimembranous_ventricular_septal_defect___Image. (unboundmedicine.com)
  • To assess the effects of the combination of SAMe ( S -adenosylmethionine) 200 mg and Lactobacillus plantarum ( L. plantarum ) HEAL9 1 × 10 9 CFU for the overall symptomatology of mild-to-moderate depression. (psychiatrist.com)
  • This 6-week randomized, double-blind, placebo-controlled study included subjects aged 18-60 years with mild-to-moderate depression (according to ICD-10 diagnostic criteria) recruited from September 17, 2018, to October 5, 2018. (psychiatrist.com)
  • 1 The moderate-severe levels of depression, which are frequent in primary care, account for two-thirds of the total number (322 million) of cases. (psychiatrist.com)
  • Mild Depression can affect people in many ways, but it usually begins with a feeling of sadness that doesn't go away. (depressionals.com)
  • How does mild depression feel? (depressionals.com)
  • Even though mild depression can be difficult to diagnose, it is relatively easy to treat. (depressionals.com)
  • Various alternative remedies can treat mild depression, including St. John's Wort and melatonin supplements. (depressionals.com)
  • If mild depression is left untreated it can become more severe. (depressionals.com)
  • How does moderate depression feel? (depressionals.com)
  • There are many similarities between mild and moderate depression. (depressionals.com)
  • Cognitive-behavioral therapy (CBT) is also used in some cases of moderate depression. (depressionals.com)
  • We thus propose an alternative hypothesis "Gender differences in self-reporting symptom of depression," suggesting mild-moderate depression tends to be reported more often by females, and severe depression and suicide tend to be reported more often by males. (frontiersin.org)
  • Objectives To assess the efficacy of hydroxychloroquine on mild-moderate COVID-19 patients in South Korea. (medrxiv.org)
  • [4] Similarly, neonates with mild HIE frequently escape attention, despite mild HIE being more prevalent than moderate and severe HIE in many contexts and there being evidence suggesting adverse neurological and long-term developmental outcomes in this group. (scielo.org.za)
  • The present study, with a follow-up of 12 months, included 54 adolescent and young adult subjects with mild to moderate facial acne, which aimed to replicate a real-life context of use. (farmaimpresa.com)
  • But in some cases - more commonly in older people and in people with underlying health issues - a mild case can progress to a moderate case that could require some supportive care such as fluids for dehydration, typically in an emergency room or urgent care center, especially if hospitals are overwhelmed by the most acute cases. (ijpr.org)
  • Researchers say that the findings may have implications for how babies are screened for hearing loss and how mild-to-moderate hearing loss in children is managed by healthcare providers. (neurosciencenews.com)
  • Most negative reviews had to do with hearing in noise (a problem for most people with most aids so this is not peculiar to these aids), with the aids not being powerful enough (I think these people had more than just a moderate hearing loss), and reliability. (hearinglosshelp.com)
  • This study will determine the effects of yoga on the psychological wellbeing of people with mild-to-moderate PD and will compare these effects with those of stretching and resistance training exercises. (biomedcentral.com)
  • Those who live often get back most of their normal lung function, but many people have permanent (usually mild) lung damage. (medlineplus.gov)
  • Jabra has released the Enhance Plus earbuds - aimed at assisting people who have mild to moderate hearing loss. (slashgear.com)
  • [4,8,11] Conversely, neonates with moderate HIE are more variable and their outcomes more difficult to predict. (scielo.org.za)
  • Few existing studies involve a wide spectrum of individuals with predominantly mild to moderate road traffic injuries and examine long-term outcomes after accounting for a broad range of contributing, confounding and compensation-related factors. (bmj.com)
  • We believe it can be considered an effective adjunctive therapy in selected cases of mild / moderate obesity. (alliedacademies.org)
  • [12] The present study aimed to describe and compare factors associated with mild and moderate HIE in a sample of South African neonates. (scielo.org.za)
  • Our results from a study in health care workers without known co-morbidities indicate that mild-to-moderate COVID-19 is associated with increased sNfL levels. (springer.com)
  • This is a prospective observational study on 39 infants in our neonatal intensive care unit investigating the effects of early iNO in premature infants with mild-to-moderate RDS. (bmj.com)
  • The mild group's APGAR scores were significantly higher than those of the moderate group at five (p=0.012) and ten minutes (p=0.022). (scielo.org.za)
  • To evaluate ventilatory functional restrictions during a maximal exercise tolerance test in idiopathic scoliosis patients with mild and moderate curves and to compare them with the results obtained in healthy adolescents matched in age undergoing similar test. (nih.gov)
  • However, most commonly reported adverse events were transient mild to moderate erythema, sting, or a warming feeling at the application site. (medscape.com)
  • A prospective, comparative design was used to describe factors among South African neonates with mild (n=13) and moderate (n=33) HIE in an urban tertiary academic hospital. (scielo.org.za)
  • Deafness in early childhood is known to lead to lasting changes in how sounds are processed in the brain, but new research published today in eLife shows that even mild-to-moderate levels of hearing loss in young children can lead to similar changes. (neurosciencenews.com)
  • However, until now relatively little was known about the effects of mild-to-moderate hearing loss during childhood. (neurosciencenews.com)
  • A research team led by Dr Lorna Halliday, now at the MRC Cognition and Brain Sciences Unit, University of Cambridge, used an electroencephalogram (EEG) technique to measure the brain responses of 46 children who had been diagnosed with permanent mild-to-moderate hearing loss while they were listening to sounds. (neurosciencenews.com)
  • We know that children's brains develop in response to exposure to sounds, so it should not be too surprising that even mild-to-moderate levels of hearing loss can lead to changes in the brain," says Dr Axelle Calcus, lead author of the paper, from PSL University, Paris. (neurosciencenews.com)
  • Current screening programmes for newborn babies are good at picking up moderate-to-profound levels of hearing loss, but not at detecting mild hearing loss. (neurosciencenews.com)
  • However, less is known about the effects of mild-to-moderate sensorineural hearing loss (MMHL) during development. (neurosciencenews.com)
  • If you have a mild to moderate sloping hearing loss, and can't afford expensive hearing aids costing several thousand dollars, here is another option available to you. (hearinglosshelp.com)
  • Benvitimod has some local irritation, but it is mild to moderate. (medscape.com)
  • A mild case of COVID-19 in and of itself is not dangerous. (ijpr.org)
  • If you've seen a dermatologist or another healthcare professional, you may have heard your case described as mild, moderate, or severe. (healthline.com)
  • For individuals diagnosed with mild to moderate sleep apnea, particularly those who tend to sleep on their backs and stomachs, dental devices have shown to improve sleep and reduce the frequency and loudness associated with snoring. (bhdentists.com)
  • Few reports have dealt with cardiorespiratory response to maximal exercise in adolescent idiopathic scoliosis with mild to moderate curves. (nih.gov)
  • Although patients with mild or moderate scoliosis do not exhibit cardiopulmonary restrictions in basal static conditions, they do show a significant lower tolerance to maximal exercise. (nih.gov)