• Aneurysms included six middle cerebral artery aneurysms, one anterior communicating artery aneurysm, one posterior communicating artery aneurysm, one basilar artery aneurysm, and one T-shaped carotid aneurysm. (nih.gov)
  • The purpose of this study is to retrospectively review our experience with stent-assisted embolization of patients with an acutely ruptured cerebral aneurysm. (surgicalneurologyint.com)
  • Medical records and imaging were reviewed for 36 patients who underwent stent-assisted embolization of a ruptured cerebral aneurysm. (surgicalneurologyint.com)
  • Postprocedural 3T-MRA was performed in a cohort of 39 patients undergoing EN stent-assisted intracranial aneurysm coiling. (ajnr.org)
  • Microsurgical clipping of middle cerebral artery aneurysm The following are video recordings of surgical procedures from the Department of Neurosurgery of Saint John's Hospital of Budapest. (videotorium.hu)
  • Flow diversion for basilar apex aneurysm s has rarely been reported. (neurosurgery.directory)
  • Toulouse University Hospital, Yale School of Medicine, New Haven ), was performed from 2009 to 2016 to identify patients with basilar apex aneurysm s treated with flow diversion . (neurosurgery.directory)
  • Flow diversion for the treatment of basilar apex aneurysm s results in acceptable occlusion rates in highly selected cases. (neurosurgery.directory)
  • Flow diversion is a feasible technique with an efficacy demonstrated at a midterm follow-up, especially in the case of basilar apex aneurysm recurrences after previous endovascular treatments. (neurosurgery.directory)
  • A 73-year-old male was previously treated for an unruptured 11-mm basilar apex aneurysm with stent-assisted coiling using a Neuroform stent. (neurosurgery.directory)
  • We performed Y-stenting of the basilar bifurcation using three PFEDs, and was recoiled the aneurysm sac. (neurosurgery.directory)
  • An arterial aneurysm is a localised abnormal dilatation of an artery due to a weakness in the arterial wall. (patient.info)
  • The artery wall can balloon out symmetrically to form a 'fusiform' aneurysm or there can be a local 'blow-out' to form a 'saccular' aneurysm. (patient.info)
  • A cerebral aneurysm is defined as a local outpouching of an intracranial artery and can either be saccular or fusiform. (intechopen.com)
  • Intravascular stent and endovascular coil placement for a ruptured fusiform aneurysm of the basilar artery. (keyopinionleaders.com)
  • Cerebral digital subtraction angiography (DSA) revealed a very small aneurysm in the dorsal side of the AcomA [ Figure 1a and b ]. (surgicalneurologyint.com)
  • Through cerebral angiography, the sign has been demonstrated to correspond to embolic or atherosclerotic occlusion of an artery. (wikipedia.org)
  • In-stent thrombotic occlusion is a serious ischemic complication that can also result in ischemia in the distal perfusion territory and the territory of side branches for the artery in which the flow diverter (FD) stent is deployed. (thejns.org)
  • Occlusion of the middle cerebral artery can lead to paralysis or weakness of the contralateral face and arm as well as sensory loss of the contralateral face and arm. (picmonic.com)
  • Occlusion of the middle cerebral artery can lead to paralysis or weakness of the contralateral face and arm due to involvement of the primary motor cortex. (picmonic.com)
  • Occlusion of the middle cerebral artery can lead to contralateral loss of sensation of the upper limb and face due to involvement of the primary sensory cortex. (picmonic.com)
  • BACKGROUND AND PURPOSE: To test the safety and recanalization efficacy of intra-arterial local delivery of plasminogen activators in acute ischemic stroke, a randomized trial of recombinant pro-urokinase (rpro-UK) versus placebo was undertaken in patients with angiographically documented proximal middle cerebral artery occlusion. (keyopinionleaders.com)
  • Treatment with a single stent could achieve complete occlusion especially if the aneurysms occur elsewhere than the internal carotid artery. (surgicalneurologyint.com)
  • Radiological and angiographic imaging was reviewed to document the location of the vascular occlusion, Thrombolysis in Cerebral Infarction (TICI) flow postprocedure, and procedural complications. (bmj.com)
  • The most common are saccular aneurysms, which are described as being berry-shaped swellings occurring at the bifurcation of arteries. (patient.info)
  • Most aneurysms occur singly with the most frequent sites being the circle of Willis and the bifurcation of the middle cerebral artery. (patient.info)
  • Congenital saccular: arterial dilatations of less than 2.5 mm that appear in the bifurcation of the arteries of the circle of Willis. (patient.info)
  • The cervical (extracranial) internal carotid artery is affected in 75% of patients (usually approximately 2 cm distal to the bifurcation) and the extracranial vertebral artery in 15% of patients. (medscape.com)
  • Any of the arteries that arise from a bifurcation of the aorta supplying the pelvic or abdomen. (mcw.edu)
  • These findings are consistent with our hypothesis that nicotine acts on nAChRs on presynaptic sympathetic nerve terminals to release NE, which then acts on presynaptic β 2 -adrenoceptors located on the neighboring NOergic nerve terminals, resulting in release of NO and dilation of porcine basilar arteries. (aspetjournals.org)
  • Presynaptic beta(2)-adrenoceptors mediate nicotine-induced NOergic neurogenic dilation in porcine basilar arteries. (lookformedical.com)
  • In medicine, the dense artery sign or hyperdense artery sign is an increased radiodensity of an artery as seen on computer tomography (CT) scans, and is a radiologic sign of early ischemic stroke. (wikipedia.org)
  • The proposed study is relevant to public health because narrowing of brain arteries is one of the most common causes of stroke worldwide. (clinicaltrials.gov)
  • Compelling evidence suggests novel antithrombotic medications could reduce the rate of stroke in patients with narrowed brain arteries. (clinicaltrials.gov)
  • The proposed study will directly compare novel antithrombotic medications to standard care antiplatelet medications for preventing stroke and death from vascular causes in patients with narrowed brain arteries. (clinicaltrials.gov)
  • Miller, A. A. , Dusting, G. J. , Roulston, C. L. and Sobey, C. G. (2006) NADPH-oxidase activity is elevated in penumbral and non-ischemic cerebral arteries following stroke. (gla.ac.uk)
  • At 24 h after stroke, NADPH-stimulated superoxide production by arteries from the infarcted core did not differ from levels generated by arteries from control rats, whereas levels were significantly lower 72 h after stroke. (gla.ac.uk)
  • However, at both time points after stroke, superoxide production by arteries from the ischemic penumbra was 8-fold greater than levels generated by arteries from control rats. (gla.ac.uk)
  • Surprisingly, even in the non-ischemic arteries from the contralateral hemisphere and in the basilar artery, superoxide production was increased ∼ 4- to 6-fold at 24 h, but had returned to normal 72 h after stroke. (gla.ac.uk)
  • The blockage of an artery in the brain by a clot (thrombosis) is the most common cause of a stroke. (medicinenet.com)
  • Another type of stroke may occur when a blood clot or a piece of atherosclerotic plaque (cholesterol and calcium deposits on the wall of the inside of the heart or artery) breaks loose, travels through the bloodstream, and lodges in an artery in the brain. (medicinenet.com)
  • Usually, these clots remain attached to the inner lining of the heart, but occasionally they can break off, travel through the bloodstream (embolize), block a brain artery, and cause a stroke. (medicinenet.com)
  • A cerebral hemorrhage (bleeding in the brain) causes stroke symptoms by depriving blood and oxygen to parts of the brain in a variety of ways. (medicinenet.com)
  • There was 1 mortality in a patient (6.3%) who experienced posterior cerebral artery and cerebellar stroke s as well as subarachnoid hemorrhage after the placement of a flow diverter . (neurosurgery.directory)
  • While some studies have reported that males and females are affected equally in extracranial carotid dissections, the Cervical Artery Dissection and Ischemic Stroke Patients (CADISP) group reported that cervical artery dissection was more common in men and men were older at onset. (medscape.com)
  • Thrombolysis in cervical artery dissection--data from the Cervical Artery Dissection and Ischaemic Stroke Patients (CADISP) database. (medscape.com)
  • Exclusion criteria included recent acute complications such as diabetic ketoacidosis and hyperglycemic hyperosmolar state, severe and recurrent hypoglycemic events in the previous 3 months, a history of hepatic or renal impairment, or of other diseases that can influence glucose metabolism, including recent acute cerebral stroke, acute myocardial infarction, malnutrition, and cancers. (biomedcentral.com)
  • The nAChR subtype mediating nicotine-induced dilation in isolated porcine basilar arterial rings denuded of endothelium was therefore examined pharmacologically and immunohistochemically. (aspetjournals.org)
  • Studies were performed on isolated cerebral and peripheral arterial segments from the rat to define contractile receptors for 5-hydroxytryptamine (5-HT) and to elucidate the responses to calcium channel blockers in relation to their effects on potassium-induced contractions. (aspetjournals.org)
  • In the presented case, a young female patient with fulminant refractory DCI and CV, despite induced hypertension and nimodipine application, was treated with three-vessel continuous intra-arterial infusion and additional repetitive angioplasty of the basilar and middle cerebral arteries using a stent retriever, leading to a good clinical outcome. (thejns.org)
  • We report a unique rescue strategy involving implantation of an additional intra-arterial catheter into the vertebral artery and repetitive stent retriever dilatations of the middle cerebral and basilar arteries as an extra therapy for continuous intra-arterial nimodipine vaspospasmolytic therapy in three vessel territories, resulting in a very good clinical outcome. (thejns.org)
  • True arterial aneurysms involve all three layers of the artery wall (intima, media and adventitia). (patient.info)
  • In about 25% of cases, there is co-existing arterial occlusive disease in the renal or lower extremity arteries. (patient.info)
  • Los aneurismas saculares son la variante más común y tienden a formarse en los puntos de ramificación arterial en el POLÍGONO DE WILLIS en la base del encéfalo. (bvsalud.org)
  • The aim of this study was to better assess the long-term durability of endovascular coiling of cerebral aneurysms with Guglielmi detachable coils (GDCs) and the real rate of second treatment for ruptured aneurysms alone. (ajnr.org)
  • Stent-assisted coil embolization is an option for treatment of ruptured wide neck ruptured aneurysms and for salvage treatment during unassisted embolization of ruptured aneurysms but complications and retreatment rates are higher than for routine clipping or coiling of cerebral aneurysms. (surgicalneurologyint.com)
  • The authors demonstrate the technical feasibility of using intravascular stents in conjunction with electrolytically detachable coils (Guglielmi detachable coils [GDCs]) for treatment of fusiform, broad-based, acutely ruptured intracranial aneurysms and review the literature on endovascular approaches to ruptured aneurysms and cerebral stent placement. (keyopinionleaders.com)
  • Evidence has accumulated that there is increased atherosclerosis/arteriosclerosis of the intracranial arteries in AD and that this may be additive or synergistic with respect to the generation of hypoxia/ischemia and cognitive dysfunction. (dovepress.com)
  • Induced hypertension, hypervolemia, and hemodilution (ie, "triple-H therapy") aimed to maintain adequate cerebral perfusion pressure in the setting of impaired cerebrovascular autoregulation. (medscape.com)
  • Macrovascular diseases such as coronary artery disease and cerebrovascular disease are major complications of type 2 diabetes. (biomedcentral.com)
  • Transcranial Doppler (TCD) is a noninvasive, less expensive, safe, and harmless technique being commonly used studying main intracranial arteries especially in cerebrovascular occlusive disease. (biomedcentral.com)
  • Patients with large basilar apex aneurysms treated with a flow-diverter stent were included in the study. (neurosurgery.directory)
  • age range, 44-58 years) received flow-diverter stent for basilar apex aneurysms. (neurosurgery.directory)
  • 70% stenosis of an intracranial artery (i.e. (edu.hk)
  • At 24 h or 72 h post-administration of ET-1, the MCA and its branches within the ipsilateral penumbra and infarcted core, corresponding arteries in the contralateral hemisphere, and basilar artery were excised. (gla.ac.uk)
  • In this study, ISA was detectable by 3T-MRA in a significant proportion of patients undergoing EN stent-assisted coiling of ICA aneurysms in a vessel geometry− and stent-deployment location−dependent manner. (ajnr.org)
  • 8 - 10 Because this finding may be associated with adverse clinical events such as late stent thrombosis 10 , 11 in the coronary circulation, we sought to identify the presence of any ISA within the intracranial circulation in patients undergoing stent-mediated coiling by using the self-expanding intracranial EN (Cordis, Miami Lakes, Florida). (ajnr.org)
  • An additional 6 patients who underwent prospective 3T-MRA imaging within 3 days of EN deployment between June 2007 and September 2008, as part of a pilot study on the utility of 3T-MRA in randomly selected patients following stent-coiling, were also included in the study. (ajnr.org)
  • Sixteen consecutive patients (median age 54.5 yr) underwent 18 procedure s to treat 16 basilar apex aneurysms with either the Pipeline Embolization Device ( Medtronic ) or Flow Redirection Endoluminal Device ( Microvention ). (neurosurgery.directory)
  • Monitoring microcirculatory flow offers the potential to enhance monitoring in the care of critically ill patients, and imaging retinal blood flow during critical illness offers a potential biomarker for cerebral microcirculatory perfusion. (springeropen.com)
  • Retinal changes may, therefore, associate with CBF in critically ill patients, offering a novel biomarker to monitor in real-time and reduce cerebral hypoperfusion. (springeropen.com)
  • This study assessed its validity in determining cerebral small vessel disease in patients with type 2 diabetes mellitus. (who.int)
  • Transcranial doppler may be useful in early diagnosis of cerebral small vessel disease in patients with type 2 diabetes mellitus. (who.int)
  • La vitesse d'écoulement du flux sanguin et l'index de pulsatilité ont été mesurés dans les artères carotides internes intercrâniennes, les artères basilaires et cérébrales moyennes d'un échantillon de 141 patients diabétiques sans autre facteur de risque et de 132 témoins en bonne santé appariés pour l'âge et le sexe. (who.int)
  • Les patients ont été répartis en deux groupes : 73 patients souffrant d'un diabète compliqué dans le premier groupe et 68 patients atteints d'un diabète non compliqué dans le deuxième groupe. (who.int)
  • The long-term durability of Guglielmi detachable coil (GDC) embolization of cerebral aneurysms is still unknown. (ajnr.org)
  • Little data are available on the ability of the stent struts to maintain vessel-wall apposition once deployed in the tortuous cerebral vasculature and the prevalence of ISA. (ajnr.org)
  • Correlating our findings with angiographic FPCT, we describe here a new crescent-shaped flow signal intensity external to the stent struts on 3T-MRA as a marker for ISA in EN-treated aneurysms and describe the morphologic characteristics of target vessels that predispose to poor stent−vessel wall apposition. (ajnr.org)
  • Extracranial vertebral artery dissections and multiple vessel dissections are more common in women than in men. (medscape.com)
  • Linn J, Pfefferkorn T. "Noncontrast CT in Deep Cerebral Venous Thrombosis and Sinus Thrombosis: Comparison of Its Diagnostic Value for Both Entities. (wikem.org)
  • Since 1991, endovascular treatment (EVT) of cerebral aneurysms has experienced a revolution, with the introduction of platinum coil technology ( 1 - 2 ). (ajnr.org)
  • More recently, application of diffusion-weighted MRI has demonstrated silent thromboembolic events associated with endovascular treatment of unruptured cerebral aneurysms. (medscape.com)
  • AVM is characterized by a tortuous tangle of arteries & veins with agenesis of interposing capillary system. (plus100years.com)
  • Delayed cerebral ischemia (DCI) and cerebral vasospasm (CV) are severe complications of spontaneous subarachnoid hemorrhage (SAH) contributing to an inferior outcome. (thejns.org)
  • Reactive oxygen species play a role in neuronal damage following cerebral ischemia-reperfusion. (gla.ac.uk)
  • Thus, the activity of NADPH-oxidase is enhanced in cerebral arteries from the ischemic penumbra at 24 h and 72 h following cerebral ischemia. (gla.ac.uk)
  • Medical therapy of cerebral aneurysms involves general supportive measures and prevention of complications for individuals who are in the periprocedural period or are poor surgical candidates. (medscape.com)
  • Rarely, a hypodense artery sign can occur due to fat embolism. (wikipedia.org)
  • Identification of the dense artery sign is often based on subjective interpretation and false positives may occur. (wikipedia.org)
  • It stimulates both the alpha- and beta- adrenergic systems, causes systemic VASOCONSTRICTION and gastrointestinal relaxation, stimulates the HEART, and dilates BRONCHI and cerebral vessels. (lookformedical.com)
  • Flow Diversion for the Treatment of Basilar Apex Aneurysms. (neurosurgery.directory)
  • B , The opticocarotid triangle, located between the optic nerve and the carotid and anterior cerebral arteries, has been opened with gentle retraction to expose the basilar apex and the ipsilateral oculo-motor nerve passing forward between the PCA and SCA. (neurosurgicalatlas.com)
  • E , The carotid artery has been elevated to expose the basilar artery apex through the interval between the carotid artery and oculomotor nerve. (neurosurgicalatlas.com)
  • We sought to determine the ionic mechanisms of isoproterenol-induced hyperpolarization in the rat mesenteric resistance artery, as well as the age-related changes in isoproterenol-induced hyperpolarization and their underlying mechanisms. (lookformedical.com)
  • This characteristic of EN coiling at this potentially tortuous location should be taken into account when selecting an endovascular strategy. (ajnr.org)
  • Carotid artery disease in NIDDM diabetes. (who.int)
  • Results from double-labeling immunohistochemical studies in whole-mount porcine basilar and middle cerebral arteries and in cultured porcine superior cervical ganglia (SCG) indicated that α 7 -nAChR- and tyrosine hydroxylase immunoreactivities were colocalized in same nerve fibers. (aspetjournals.org)
  • In contrast, mortality rates for intracranial carotid and basilar dissections approach 70% or higher. (medscape.com)
  • Assessment and maintenance of end-organ perfusion are key to resuscitation in critical illness, although there are limited direct methods or proxy measures to assess cerebral perfusion. (springeropen.com)
  • Cerebral blood flow (CBF) is reduced and autoregulation impaired in sepsis, but current methods to image CBF do not reproducibly assess the microcirculation. (springeropen.com)
  • Our experiments reveal that total cerebral blood flow was 20% lower in the AD group than in the NDC group, and that these values were directly correlated with pulse pressure and cognitive measures. (dovepress.com)
  • Serial TCD may be employed to detect trends in cerebral blood flow during this period. (medscape.com)
  • Parallel mechanisms autoregulate retinal and cerebral microcirculation to maintain blood flow to meet metabolic demands across a range of perfusion pressures. (springeropen.com)
  • This review discusses the relationship between cerebral and retinal blood flow, and the relevance of that relationship to systemic pathology and monitoring microcirculatory perfusion in critical illness, focussing more on sepsis. (springeropen.com)
  • The aim of this study was to assess normal population values of cerebral blood flow velocity and its variation over age and gender in a given population. (biomedcentral.com)
  • Cerebral blood flow velocities among females were relatively higher than males. (biomedcentral.com)
  • Cerebral blood flow velocity of left side was relatively higher than right side. (biomedcentral.com)
  • Compared to previous studies, cerebral blood flow velocity in this population was relatively higher. (biomedcentral.com)
  • Strokes are a heterogeneous group of disorders involving sudden, focal interruption of cerebral blood flow that causes neurologic deficit. (msdmanuals.com)
  • Cerebral blood flow in diabetes mellitus: evi- tions , 1996, 10:228-242. (who.int)
  • Cocaine use has been associated with cerebral, aortic, visceral and peripheral aneurysms. (patient.info)