• Biosensors are a kind of analytical tool that combine recognition biomolecules with a transducer, which transforms (bio)chemical information into a chemical or physical signal. (sigma-not.pl)
  • He is particularly interested in the development of integrated chemo-enzymatic microfluidic reactors for the synthesis of commercially useful compounds. (ucl.ac.uk)
  • The rapid test is based on a new plastic microfluidic chip where the bacteria are trapped and methods for analysing bacterial growth at single-cell level," says PhD student Özden Baltekin, who performed most of the experimental work. (eurekalert.org)
  • Collaboration between researchers and the manufacturers of analytical equipment allow an ongoing cycle of research and development to provide the analytical methodologies and instrumentation capabilities needed to implement the latest research projects. (news-medical.net)
  • In response, multiple spotting techniques are being evaluated to balance blood volume and sensitivity limitations, and the introduction of increasingly sensitive LCMS instrumentation, for example UPLC, are helping to address this challenge. (samedanltd.com)
  • Microfluidic analytical techniques he has developed include methods for measuring the permeability of cell membranes to druglike molecules and techniques for measuring ionic currents through membrane proteins. (selectbiosciences.com)
  • Over the past 20 years, great progress has been made by her research group to develop new CL/ECL-based analytical concept and principle and to better understand these analytical methods. (springer.com)
  • These results have provided novel strategies to address fundamental challenges of CL and ECL as powerful analytical and bioanalytical methods. (springer.com)
  • Initial investigations indicate SRM is a promising analytical tool for improving pre-clinical analysis methods for drug development and for applications in clinical diagnostics. (ku.edu)
  • By taking advantage of their desirable performance metrics, we have developed a variety of innovative label-free analytical platforms. (ku.edu)
  • To develop a rapid and sensitive assay based on microfluidic isoelectric focusing, we previously prepared reagent-release capillaries retaining ampholytes by physical adsorption on the inner surface of a short capillary, which were then applied to isoelectric focusing. (go.jp)
  • Microfluidic whole genome haplotyping is a technique for the physical separation of individual chromosomes from a metaphase cell followed by direct resolution of the haplotype for each allele. (wikipedia.org)
  • In our group, patterned regular sieving structures and nanofilters have been sought as an alternative to conventional separation method: recent developments in micro-nanofluidic sieves and filters have demonstrated superior performance for both analytical and preparative separation of various physiologically relevant macromolecules, including proteins. (mit.edu)
  • During the separation of amino acids labeled with caged fluorescein using a photolytic optical gating technique, consecutive online injections were performed on a sample mixture containing 50 nM labeled arginine (Arg), glutamic acid (Glu) and aspartic acid (Asp). (photonics.com)
  • Chemistries were compared in terms of immobilization and hybridization density, stability under microfluidic flow-induced shear stress, and stability after extended storage in aqueous solutions. (springer.com)
  • In conventional isoelectric focusing techniques using microfluidic channels, complicated liquid manipulations are required, which can decrease analytical performance such as the reproducibility of a focusing position. (go.jp)
  • An analytical or preparatory system comprised as a base unit, an adapter, and a substrate. (google.com)
  • Microfluidic system is often interpreted to a miniaturized version of bioanalytical laboratory. (hindawi.com)
  • The system goes beyond pre-programmed pipetting operations for common techniques, like reverse pipetting and aliquoting , and allows technicians to easily create, save, and execute pipetting applications from start to finish. (thefreedictionary.com)
  • We developed a vacuum compatible microfluidic interface, System for Analysis at the Liquid Vacuum Interface (SALVI), to enable direct observations of liquid surfaces and liquid-solid interactions using time-of-flight secondary ion mass spectrometry (ToF-SIMS). (selectbiosciences.com)
  • In this study, we use a 2D sensor readout system, called VisiSens, along with planar optical oxygen sensor foils integrated in microfluidic channels to investigate oxygenation in microfluidic cell culture. (genengnews.com)
  • B) The ratiometric readout was recorded by the VisiSens A1 oxygen imaging system (PreSens) controlled by proprietary software VisiSens Analytical 1 (PreSens) for data acquisition and processing. (genengnews.com)
  • We present a microfluidic vasculature system to model interactions between circulating breast cancer cells with microvascular endothelium at potential sites of metastasis. (nih.gov)
  • We used this microfluidic system to produce site-specific stimulation of microvascular endothelium with CXCL12, a chemokine strongly implicated in metastasis. (nih.gov)
  • The idea is that the dye can be used as a noninvasive way to map the range of temperatures occurring within a microfluidic system during heating and, in turn, provide a means of calibrating that system for experiments. (redorbit.com)
  • They are exploring the use of LEDs to provide the UV and blue wavelengths now generated by the laser, developing caged fluorescent labels that have faster reaction dynamics and integrating the system into a microfluidic platform. (photonics.com)
  • Early in 2012, MIT scientists reported on the development of a postage stamp-sized microchip capable of sorting cells through a technique, known as cell rolling, that mimics a natural mechanism in the body. (phys.org)
  • Overall, WGM resonators are demonstrated as sensitive label-free detectors for the development of a variety of analytical tools. (ku.edu)
  • In this work, I report the development of an electrostatic microvalve that is fabricated with simple, soft-lithographic techniques. (illinois.edu)
  • Development of the Space-Resolved Solid-Phase Microextraction Technique and Its Application to Biological Matrices. (uwaterloo.ca)
  • These limitations have led to the development of so-called gating techniques that enable injection into a continuously flowing solution. (photonics.com)
  • Some of the possible clinical applications for this technique include phasing of multiple mutations when parental samples are unavailable, preimplantation genetic diagnosis, prenatal diagnosis and in the characterization of cancer cells. (wikipedia.org)
  • The nCS1 instrument will add an additional orthogonal high-resolution technique to our current nanoparticle characterization capabilities. (nanotech-now.com)
  • FortéBio's Octet instruments are an ideal replacement for ELISA, HPLC, and SPR techniques in quantification of antibodies and recombinant proteins and in testing product potency for lot release. (bioprocessintl.com)
  • Scientists today are challenged in gathering a complete understanding using available techniques. (genengnews.com)
  • Spectradyne s CEO Jean-Luc Fraikin described the importance of the deal: This partnership will expand access to the powerful insights that our technology delivers by providing a low barrier to entry for scientists who are new to Microfluidic Resistive Pulse Sensing (MRPS). (nanotech-now.com)
  • Particle Technology Labs is already a trusted provider of high-quality analytical services in many of our target markets, and Spectradyne will provide PTL with increased access to biological markets, including extracellular vesicle research in particular. (nanotech-now.com)
  • While the technique did not achieve widespread adoption, it has more recently been championed by Spooner et al for the determination of drugs and metabolites in biological samples using manually extracted DBS coupled to LC-MS/MS (2). (samedanltd.com)
  • We have developed a high-throughput droplet-microfluidic approach for barcoding the RNA from thousands of individual cells for subsequent analysis by next-generation sequencing. (nih.gov)
  • We are interested in carrying out various chemical and biochemical analysis which are enhanced by the use of modern analytical techniques and microfluidic nanotechnology. (sfu.ca)
  • Traditional monitoring techniques are typically based on laboratory analysis of field-collected samples that require considerable effort and expense, and the sample may change before analysis. (environmental-expert.com)
  • A silicon microneedle array with integrated microfluidic channels is presented, which is designed to extract dermal interstitial fluid (ISF) for biochemical analysis. (spie.org)
  • As one of the premier analytical testing facilities worldwide, specializing in pharmaceutical testing, PTL is adding the Spectradyne nCS1 nanoparticle analysis capability to its comprehensive set of available tools. (nanotech-now.com)
  • The analytical strategy of studying a comprehensive 'profile' of metabolites in medicine was introduced by Linus Pauling and colleagues in the late 1960s, stating that " the thorough quantitative analysis of body fluids might permit differential diagnosis of many diseases in a more effective way than is possible at the present time " [ 5 ]. (soc-bdr.org)
  • To further explore WGM sensing applications, we developed a new analytical technique for label-free analysis of surfaces. (ku.edu)
  • A common DNA analysis technique, for example, depends heavily on precise temperature cycling. (redorbit.com)
  • Ambient ionization techniques, direct analysis in real time (DART) and desorption atmospheric pressure photoionization (DAPPI), were combined with travelling wave ion mobility-mass spectrometry. (helsinki.fi)
  • The micro-magnetofluidic method is the control of magnetic fluids by an applied magnetic field on a microfluidic platform, offering wireless and programmable control of the magnetic droplets. (wikipedia.org)
  • Spectradyne is happy to announce a new partnership with Particle Technology Labs to provide analytical measurement services using its nCS1TM instrument. (nanotech-now.com)
  • Particle Technology Labs is a premier analytical testing facility located in Downers Grove, Illinois, that is ISO certified to provide a broad array of measurement services. (nanotech-now.com)
  • Many commonly used measurement techniques for oxygen monitoring are not applicable in such small volumes, consume oxygen during the measurement process, or directly affect the cells. (genengnews.com)
  • Examples of some elementary techniques used to characterise LEDs including measurement of emission spectra will be conducted as hands-on experiments. (pittcon.org)
  • The confluence reactor has also been used in conjunction with imaging techniques in order to provide experimental understanding of the concentration distributions arising from hydrodynamic voltammetric measurements. (cam.ac.uk)
  • Previous studies have demonstrated that flow-induced shear stress induces a motile and aggressive tumor phenotype in a microfluidic model of 3D ovarian cancer. (spie.org)
  • In many cases the various reactants are held within the same vessel which severely limits the application of these techniques to quantitative mechanistic and kinetic investigation of rapid chemical reactions. (cam.ac.uk)
  • Researchers at Oregon State University have developed an improved technique for using magnetic nanoclusters to kill hard-to-reach tumors. (phys.org)
  • To demonstrate this microfluidic flow-flash technique, the researchers used it to probe the kinetics of CO recombination or oxygen binding to myoglobin after laser-induced dissociation of CO from horse heart myoglobin. (photonics.com)
  • The technique enabled researchers to confirm the presence of abnormal chromosomes typical of Down syndrome with great accuracy. (biotech-weblog.com)
  • The researchers are focusing on three approaches to improve their technique. (photonics.com)