• The system contains a processed swellable material, composed of carbomer produced by extrusion-spheronisation which is able to generate viscosity on contact with water, an active drug substance exhibiting sustained release properties from polymethacrylate copolymer coated beads, and freeze-dried cushioning beads composed of microcrystalline cellulose (MCC) and croscarmellose sodium. (umaryland.edu)
  • Orally disintegrating tablets with 8 mm in diameter were prepared using solid dispersions and excipients: mannitol, sodium croscarmellose and microcrystalline cellulose. (unizg.hr)
  • Then there is cellulose gum, which is actually methyl cellulose, hydroxypropyl methyl cellulose, or carboxymethyl cellulose derivatives that provide a smooth feeling in the mouth in processed food in which the fat content is restricted. (spectroscopyonline.com)
  • The oral dosage form of claim 1 wherein said surfactant(s) comprise one or more nonionic surfactants elected from the group consisting of lauromacrogol 400, polyoxyl 40 stearate, polyoxyethylene hydrogenated castor oil 10, 50 and 60, glycerol monostearate, polysorbate 40, 60, 65 and 80, sucrose fatty acid ester, methylcellulose and carboxymethyl cellulose.5. (patenthub.cn)
  • Combination of microcrystalline cellulose and maltodextrin has been used to formulate Oral Strips of piroxicam made by hot melt extrusion technique. (wikipedia.org)
  • Hypersensitivity to furosemide, amiloride, sulphonamides or sulphonamide derivatives, or any of the excipients of the product listed in section 6.1. (medthority.com)
  • Cellulose or microcrystalline cellulose (MCC) serves as a filler and a lubricant in different dog foods and supplements. (lignans.net)
  • The use of erythritol as soluble filler in the preparation of a stable pharmaceutical composition is disclosed. (patentsencyclopedia.com)
  • [0001] The present invention relates to the use of erythritol as a stable soluble filler in spray-dried pharmaceutical compositions and, in particular, to novel compositions comprising eythritol as excipient and the NK 3 receptor antagonist talnetant. (patentsencyclopedia.com)
  • Cellulose MCC is widely used in pharmaceutical formulations, mainly as a diluent and binder for oral tablets and capsules. (kimacellulose.com)
  • Shen Wei Ling tablets-Guangdong Pidi Pharmaceutical Co., LTD. (pdpharm.com)
  • For the first use of cellulose in a modern application, think of microcrystalline cellulose (MCC), the white powder that is one of the excipients added to pharmaceutical tablets to aid in their dissolution in aqueous environments. (spectroscopyonline.com)
  • In pharmaceutical tablets, HPMC can be used as a protective coating, and as a rate controlling release agent in timed-release formulations. (spectroscopyonline.com)
  • The aim of the study was to analyze the effect of the active pharmaceutical ingredient on the flowability of the powder and properties of tablets prepared using direct compression method. (ijpsonline.com)
  • The preformulation study confirmed that characteristics of the active pharmaceutical ingredient might have modified physicochemical properties of both powder formulations and tablets. (ijpsonline.com)
  • Its ever increasing applications in drug research include its utility in immediate release (tablets and liquids) dosage forms, sustained release dosage forms (multiparticulates and matrix tablets), topical preparations, oral liquids, organoleptic enhancements as in chewable and mouth dissolving tablets, anti-reflux, and nutraceuticals. (cellulosechina.com)
  • The formulation of tablets for instantaneous preparation of sustained release suspension was achieved by compressing a blend composed of 8.3% drug-loaded beads coated with polymethacrylates, 16.7% carbomer beads produced by extrusion-spheronisation and the freeze-dried cushioning beads. (umaryland.edu)
  • Among the most common excipients are food-based excipients such as cellulose, rice powder and other flours, both to add essential lubrication and to fill otherwise empty space inside the capsules or tablets. (lignans.net)
  • As pharmaceuticals are related to health care this should be vital part of industry to produce a product such as tablets, capsules, ointments, creams, gels and emulsions etc. with minimum variation satisfying the needs of customer. (ajptr.com)
  • Glycerol, Propylene glycol, low molecular weight polyethylene glycols, phthalate derivatives like dimethyl, diethyl and dibutyl phthalate, Citrate derivatives such as tributyl, triethyl, acetyl citrate, triacetin and castor oil are some of the commonly used plasticizer excipients. (wikipedia.org)
  • The present invention is also concerned with pharmaceutical compositions and formulations of said combinations of tenofovir disoproxil fumarate and emtricitabine, and their physiologically functional derivatives, as well as therapeutic methods of use of those compositions and formulations. (gc.ca)
  • In the development of orally sustained and controlled release drug delivery system, due to the lower cost, safety, easy production and other factors, various cellulose derivatives are widely used in the preparation of sustained-release dosage forms, of which cellulose ethers are the most commonly used water-soluble and swellable polymers. (celluloseether.com)
  • The present invention relates to pyrazolopyrimidinone derivatives of che following formula 1, their preparation method and pharmaceutical compositions containing the said derivatives. (allindianpatents.com)
  • It was found that matrices containing a swellable diluent like microcrystalline cellulose demonstrated predominantly Fickian mechanism of release, whereas soluble diluents (lactose and mannitol) contributed to a mixed mechanism of release. (unboundmedicine.com)
  • Ingredients] This product is a compound preparation, each tablet contains 0.1 g of Ganoderma lucidum dry powder, 0.2 g of mushroom extract powder, 2 mg of vitamin B6, and 0.1 g of ginseng powder. (pdpharm.com)
  • However, processing of the viscosity enhancer into beads produced by either extrusion-spheronisation with microcrystalline cellulose (MCC) using a hydroalcoholic system or powder layering onto sugar spheres using alcoholic PVP as a binder provided a solution to the problem. (umaryland.edu)
  • A novel pharmaceutical composition comprising the NK 3 receptor antagonist talnetant, povidone, erythritol and a surfactant, and a process for its preparation are disclosed. (patentsencyclopedia.com)
  • 3. A spray-dried pharmaceutical composition comprising (i) a pharmaceutical active, (ii) povidone, (iii) substantially crystalline erythritol and (iv) a surfactant. (patentsencyclopedia.com)
  • We meet the standards of Polish law and commonly used global pharmaceutical industry standards. (olimp-labs.pl)
  • Below we discuss these goals in the context of some commonly used excipients and your pet's health. (lignans.net)
  • The most basic and important excipients categories involved in tabletting include diluents/bulking agents, disintegrants, binders, lubricants, and glidants and many examples of each can be cited from the oldest to the newest literature. (cellulosechina.com)
  • Cellulose is a linear, unbranched polymer of glucose, assembled with β-1,4 linkages. (spectroscopyonline.com)
  • As an excipient for pharmaceutical formulations there are no difficulties. (kimacellulose.com)
  • A good source for checking the safety of a particular binder or other excipient is the WebMD supplements database . (lignans.net)
  • Formulation of oral drug strips involves the application of both aesthetic and performance characteristics such as strip-forming polymers, plasticizers, active pharmaceutical ingredient, sweetening agents, saliva stimulating agent, flavoring agents, coloring agents, stabilizing and thickening agents. (wikipedia.org)
  • From the regulatory perspectives, all excipients used in the formulation of oral drug strips should be approved for use in oral pharmaceutical dosage forms. (wikipedia.org)
  • Each analyzed formulation contained one model active pharmaceutical ingredient, diphenhydramine, ketoprofen or loratadine. (ijpsonline.com)
  • Included here are materials used in the preparation and/or formulation of the finished dosage form. (drugbank.com)
  • Recent progresses in pharmaceutical sciences have been primarily oriented at optimization of the safety and efficacy of pharmacotherapy. (ijpsonline.com)
  • 1 School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, China;[email protected] (Y.Y. (cupdf.com)
  • Pharmaceutical Sciences. (umaryland.edu)
  • GMP) were adopted, dealing respectively with the role, functions and training of "authorized persons" and with the manufacture of pharmaceutical excipients. (who.int)
  • These tabletting aids, which we affectionately call excipients, have been an imperative part of tabletting that forms the basis of delivering potent or non potent drugs in the form of such effective and patient-friendly unit dosage forms. (cellulosechina.com)
  • Our production lines meet the highest pharmaceutical requirements for the production of drugs and medical products. (olimp-labs.pl)
  • So, it is be used to solubilize as well as to stabilize protein drugs and other preparations. (transchem.com.au)
  • Lurasidone hydrochloride (LRS HCl) is an active pharmaceutical ingredient with extremely low aqueous solubility that makes this drug difficult to use for the treatment of psychotic disorders. (unizg.hr)
  • This column installment is an attempt to summarize this background material with the goal of then providing some insight into the chemical reactions between cellulose and certain small molecules that can change the physicochemical properties of the reacted material. (spectroscopyonline.com)
  • Considered by the industry as a versatile and safe excipient, ideal for use in oral solid dosage forms, dietary supplements, and food products. (ingredientdepot.com)
  • The Olimp Labs Research and Development Center makes it possible to uphold the highest quality and safety standards during the production of pharmaceuticals and dietary supplements. (olimp-labs.pl)
  • Raman spectra of celluloses modified for use in the pharmaceutical, food, and materials industries will be compared and analyzed, with the goal of determining spectroscopic features that can be of use in aiding in the determination of physical and chemical properties. (spectroscopyonline.com)
  • Chemically, wood, cotton, and linen are all identified as cellulose, but their physical and chemical properties can be quite different. (spectroscopyonline.com)
  • The properties of ODTs depend on many variables, including properties of excipients as well as the manufacturing process [ 12 ]. (ijpsonline.com)
  • Beta- cyclodextrin has solubilizing and stabilizing properties which make it an excellent excipient. (transchem.com.au)
  • Because of this, MCC is the most versatile and user friendly excipient among numerous available. (cellulosechina.com)
  • This product is widely used in oral preparations and foods, and is a relatively non-toxic and non-irritating substance. (kimacellulose.com)
  • Generally 5%w/w to 30%w/w of active pharmaceutical ingredients can be incorporated in the oral strip. (wikipedia.org)
  • The oral drug preparations provided by the present invention avoid inactivation of the principal ingredient during the process of pharmaceutical manufacturing and display enhanced absorption of the ingredient from the intestinal tract, particularly as a result of the addition of fatty acid(s) to the drug composition. (patenthub.cn)
  • Since this criterion is essential for the quality of the thin film and final pharmaceutical dosage form, the use of Laser Scanning Confocal Microscopy (LSCM) was recommended to follow the manufacturing process. (wikipedia.org)
  • To understand how these various products are made, we first look at the chemical and physical structure of cellulose. (spectroscopyonline.com)
  • It endorsed the concept of using simple test methods to detect counterfeit pharmaceutical products. (who.int)
  • The Committee encouraged the development of a system for the selection of comparator products to facilitate the establishment of interchangeability of multisource (generic) pharmaceutical products. (who.int)
  • This applies especially to the growing incidence of production, distribution and sale of counterfeit, spurious and substandard pharmaceutical products in both developing and industrialized countries. (who.int)
  • The Organization must continue to promote a comprehensive approach to quality assurance of pharmaceutical products. (who.int)
  • Compared to competitor products, the ratio of the various curcuminoids in our preparation corresponds to the natural one. (zeinpharma.com)
  • Special efforts have been undertaken to raise awareness of the need for regulatory measures covering the safety of and trade in starting materials - including active pharmaceutical ingredients and excipients - and GMP implementation. (who.int)
  • In the North American market, the demand for plant-based ingredients is expected to continue driving the growth of the personal care, cosmetics, and pharmaceutical industries. (ingredientdepot.com)
  • Excipients are substances that are used in supplements alongside the advertised (or "active") ingredients. (lignans.net)
  • MCC Microcrystalline Cellulose 102 meets the manufacturer's USP-NF, BP, Ph.Eur grades, adhering to quality standards of multiple pharmaceutical regulatory bodies. (ingredientdepot.com)
  • MCC is widely used in pharmaceutical, cosmetic, food and other industries. (kimacellulose.com)
  • For situations where discontinuation of therapy with one of the active agents of this medicine, or dose reduction is necessary, separate preparations of rifampicin and/or isoniazid should be used. (who.int)
  • Vigorous implementation of GMP in the local production of pharmaceuticals is the first prerequisite for prevention. (who.int)
  • The ability to make these chemical modifications depends, to a large extent, on the history of the cellulose starting material-its purity, crystallinity, and fibrillar dimensions. (spectroscopyonline.com)
  • As you can see, some types of excipients are necessary for the manufacturing, shelf life or usefulness of your supplements, while others are not. (lignans.net)
  • Thus, in thinking about the excipients in your pet's supplements, the goal is to minimize the non-essential excipients, choose the best of the essential excipients and altogether avoid the harmful ones. (lignans.net)
  • If your dog is currently on any prescribed medications, you should check with your veterinarian and/or pharmacist to make sure there are no interactions with the excipients in your dog's supplements. (lignans.net)
  • Evidence shows that problems regarding the quality assurance of pharmaceuticals persist. (who.int)
  • The development of MCC has made an extremely valuable tabletting agent available to the pharmaceutical industry and since its introduction in late 1950s, it stands today as the single most important tablet excipient developed in modern times. (cellulosechina.com)
  • All of your requirements related to Epoxy Curing Agent, Epoxy Hardener, Marine & Protective Coatings, Construction Chemicals, Phenalkamine, Microcrystalline cellulose and a lot of other Epoxy and Pharmaceutical Excipients can be procured at one place. (markskill.com)
  • In the food industry, MCC microcrystalline cellulose can be used as an important base material for functional foods, and is an ideal health food additive. (kimacellulose.com)
  • In more modern times, cellulose has been chemically modified for a variety of uses in the pharmaceutical, food, and materials industries. (spectroscopyonline.com)
  • Its wide use in pharmaceuticals, food, and cosmetics has become prevalent due to its biocompatibility and non-toxicity. (ingredientdepot.com)
  • However, microcrystalline cellulose (MCC) is an excipient that can play the roles of almost every category listed above for tablet research. (cellulosechina.com)
  • Forzest® - is a medical preparation, which belongs to Male Health category. (edbitcoin.com)
  • It has some lubricating and disintegrating effects, so it is very useful in tablet preparation. (kimacellulose.com)