• As a matter of fact, food safety is an essential public health issue for all countries since foodborne disease, whether due to microbial pathogens, biotoxins or chemical contaminants of food, represents a serious threat to the health of millions of consumers: significant serious foodborne disease outbreaks have been documented in many countries in the past and are still liable to occur in any part of the world. (who.int)
  • essential public health issue for all countries this has not, however, been the case with since foodborne disease, whether due to regard to foodborne diseases, which remain microbial pathogens, biotoxins or chemical a great challenge. (who.int)
  • they can be labeled with radionuclides and used to detect microbial pathogens. (bruker.com)
  • Avoiding or reducing the proliferation of normal airborne microbial contaminants that invariably occurs in the stagnant collection of water in air systems is crucial. (medscape.com)
  • Binding of PD-L1 to its receptors suppresses T-cell migration, proliferation and secretion of cytotoxic mediators, and restricts tumour cell killing. (nih.gov)
  • Over-expression of SOCS3 in vitro leads to decreased proliferation and reciprocally, lack of epithelial SOCS3 promotes proliferation and tumour growth in intestinal injury and cancer models. (lancs.ac.uk)
  • Intestinal-specific deletion of Pcdh20 damages epithelial cell proliferation and differentiation and causes morphological changes, including shortened crypts and microvilli. (biomedcentral.com)
  • To give another example, the international propagation of meat and bonemeal prepared from cattle affected by bovine spongiform encephalitis (BSE) caused widespread proliferation of the disease among consumers. (who.int)
  • BSE) caused widespread proliferation of hicle for transmitting hazards and causing the disease among consumers. (who.int)
  • Explore this page to review technical definitions for the contributing factors for foodborne illness outbreaks, organized around the three types of contributing factors (contamination, proliferation, and survival). (cdc.gov)
  • The authors conclude that the higher prevalence of lower respiratory tract symptoms reported among workers in carpeted areas may be related to microbial contamination of the carpet. (cdc.gov)
  • The interaction of LF with microbial surfaces-OMPs of Gram-negative bacteria in particular-has led to other antimicrobial mechanisms, such as the inhibition of microbial attachment to sub-epithelial matrix proteins and detachment of bacteria from mucosal surfaces. (ift.org)
  • A new study reports that a protein called beta cell expansion factor A (BefA) secreted by certain gut bacterial species could induce the proliferation of beta cells in young mice and zebrafish. (medicalnewstoday.com)
  • Understanding the mechanisms underlying the actions of BefA protein could help develop therapies to stimulate beta cell proliferation in individuals with diabetes. (medicalnewstoday.com)
  • In their previous work, the study authors had shown that germ-free zebrafish larvae, which show a complete absence of gut microbes, show lower levels of pancreatic beta cell proliferation during development. (medicalnewstoday.com)
  • In addition, exposure to BefA prevented this decline in beta cell proliferation in germ-free zebrafish larvae. (medicalnewstoday.com)
  • Bacteriostasic effect is enhanced when LF binds to a microbial cell surface (Dalamastri et al. (ift.org)
  • ViaFluor® Cell Proliferation Kits. (biotium.com)
  • Learn more about our wide selection of assays for cell proliferation, cell viability, and apoptosis . (biotium.com)
  • Crypt depth was measured and cell proliferation rates determined using an EdU assay. (lancs.ac.uk)
  • Examination of tissue from IEC SOCS3 knockout mice, three days post infection, showed little difference in crypt depth or inflammation but suggested an increase in cell turnover, i.e. proliferation. (lancs.ac.uk)
  • Microbial cell specific transporters recognize and bind the radiolabelled siderophores, which are then taken up by the microbe. (bruker.com)
  • RGD peptides have a high-affinity and selectivity for αvβ3 integrin, a cell-surface receptor that is overexpressed in activated endothelial cells and plays an important role in tumor angiogenesis, proliferation, invasiveness and metastatic potential. (bruker.com)
  • Nanoscale solid characterizations reveal the organic carbon to be microbial cells within the Fe-rich smectite, with cell densities locally exceeding 10 10 cells/cm 3 . (darkenergybiosphere.org)
  • Direct regulation of T cell function by microbial ligands through Toll-like receptors (TLR) is an emerging part of T cell biology. (mingsheng88.org)
  • This study stresses the importance of a stringent purification method when investigating the part of microbial ligands in T cell function. (mingsheng88.org)
  • Deletions of multiple GID subunits compromise cell proliferation, and this defect is accompanied by deregulation of critical cell cycle markers such as the retinoblastoma (Rb) tumor suppressor, phospho-Histone H3 and Cyclin A. We identify the negative regulator of pro-proliferative genes Hbp1 as a bonafide GID/CTLH proteolytic substrate. (elifesciences.org)
  • Cu and water, in an aerobic biochemical reaction, generate hydroxyl radical (OH) and reactive oxygen (O2), which can cause microbial cell proliferation to cease. (inwin-style.com)
  • The objective of this study was to assess the underlying mechanisms of mango polyphenol decreased cell proliferation and tumor volume in ductal carcinoma in situ breast cancer. (oregonstate.edu)
  • Biofilm formation occurs as a result of a sequence of events: microbial surface attachment, cell proliferation, matrix production and detachment 8 . (bvsalud.org)
  • Langerhans cell histiocytosis (LCH) is a proliferation of dendritic mononuclear cells with infiltration into organs locally or diffusely. (msdmanuals.com)
  • Гістіоцитоз легеневих клітин Лангерганса Pulmonary Langerhans cell histiocytosis (PLCH) is proliferation of monoclonal Langerhans cells in lung interstitium and airspaces. (msdmanuals.com)
  • Damage and degeneration of mucosal tissues may be due to a proliferation of cytotoxic T cells or toxic products released by degranulating eosinophils. (medscape.com)
  • However, antimicrobial drugs disrupt the normal intestinal microbial architecture and can enable proliferation of C. difficile ( 2 ). (cdc.gov)
  • In mice, intestinal-specific Pcdh20 knockout causes defects in enterocyte proliferation and differentiation, while causing morphological abnormalities. (biomedcentral.com)
  • Seawater circulation, hydrothermal alteration and microbial interactions regulate seawater chemistry and change the composition and physical properties of the lithosphere. (nature.com)
  • However, the nature of deep microbial life in oceanic crust remains poorly understood, especially where old cold basaltic rock interacts with seawater beneath sediment. (darkenergybiosphere.org)
  • proliferation could refer to an increase in the number of bacteria or the production of toxins),and survival (factors that contribute to the survival of foodborne illness agents after a process that should have eliminated or reduced them). (cdc.gov)
  • pyrogen-free accedere the management distress you conquered up with and we'll induce you a umbilical proliferation. (deadbatteries.com)
  • The origin and mechanisms of these proliferations are still poorly studied. (ualg.pt)
  • 3 Blindness may occur from damage caused by septic emboli entering the posterior segment vasculature and disseminating the organism into the surrounding tissues with subsequent microbial proliferation and inflammatory reactions. (aafp.org)
  • Sparse microbial populations persist from seafloor to basement in the slowly accumulating oxic sediment of the oligotrophic South Pacific Gyre (SPG). (darkenergybiosphere.org)
  • The first objective is to establish the algal proliferation status and monitor Asparagopsis populations and their interaction with cnidarian assemblages. (ualg.pt)
  • However, bulk carpet samples from select classrooms revealed varying concentrations of gram negative bacteria and yeasts characteristic of microbial proliferation due to elevated moisture conditions. (cdc.gov)
  • Intracellular events, such as blocking of microbial attachment factors such as fimbriae (hairlike structures) and other adhesins (putative receptors), have been observed (Naidu and Bidlack, 1998). (ift.org)
  • Microbial life inhabits deeply buried marine sediments, but the extent of this vast ecosystem remains poorly constrained. (darkenergybiosphere.org)
  • and interaction with the microbial community are summarised. (bvsalud.org)
  • Here, the distribution and faunal composition of Griesbachian microbialites from China, Iran, Turkey, Armenia, Slovenia and Hungary are investigated to determine the factors that allowed microbialite-forming microbial mats to flourish following the end-Permian crisis. (lu.se)
  • A diet high in refined sugar, like white sugar and high-fructose corn syrup, can have a negative effect on the composition of good bacteria while encouraging the proliferation of bad microbial actors in the gut. (florahealth.com)
  • Magmatic hydrothermal systems sustain a vast, hot and diverse microbial biosphere that represents a deep organic carbon source to ocean carbon budgets. (nature.com)
  • Serpentinization reactions produce highly reduced fluids with high H 2 , CH 4 and other organic molecules that provide energy for microbial life. (nature.com)
  • Approximately 0.05 GtC yr −1 of organic carbon is estimated to be produced through microbial interactions and oxidation of organic compounds within hydrothermal plumes. (nature.com)
  • Our results suggest that microbial communities widely distributed in organic-poor abyssal sediment consist mainly of aerobes that retain their metabolic potential under extremely low-energy conditions for up to 101.5 Ma. (darkenergybiosphere.org)
  • 1993). Accordingly, specific LF-binding microbial targets exist in a variety of Gram-positive and Gram-negative bacteria (Naidu et al. (ift.org)
  • We conclude that the predominance of microbial reefs following the mass extinction is restricted to short intervals of the earliest Triassic. (nature.com)
  • The third objective is to test experimentally, in situ and in the laboratory, Asparagopsis proliferation and its harmful ecological effects on cnidarians dominated benthic assemblages. (ualg.pt)
  • The study's authors had previously identified such a protein, called BefA, secreted by gut microbes that could stimulate the proliferation of beta cells in zebrafish. (medicalnewstoday.com)
  • Moreover, the authors had also identified a version of the BefA protein synthesized by gut bacteria in humans that could stimulate the proliferation of beta cells in zebrafish. (medicalnewstoday.com)
  • In the present study, the researchers further examined the mechanism through which BefA could facilitate the proliferation of pancreatic beta cells in young mice and zebrafish. (medicalnewstoday.com)
  • The PD-L1-PD-1 axis protects the host from overactive T-effector cells not only in cancer but also during microbial infections. (nih.gov)
  • Here we show that microbial cells are densely concentrated in Fe-rich smectite on fracture surfaces and veins in 33.5- and 104-million-year-old (Ma) subseafloor basaltic rock. (darkenergybiosphere.org)
  • Open in a separate window Figure 5 IMACS- and IMACS/FACS- CD4+ T cells differ in their costimulation requirements for proliferation and cytokine secretionCD4+ T cells were purified by IMACS or IMACS/FACS and cultured (105cells/well) in anti-CD3 coated (1C10 g/ml) flat-bottom 96 well plates with soluble anti-CD28 (5 g/ml). (mingsheng88.org)
  • These results suggest that mango polyphenols and their major microbial metabolite, pyrogallol, inhibit proliferation of breast cancer cells through ROS-dependent up-regulation of AMPK and down-regulation of the AKT/mTOR pathway. (oregonstate.edu)
  • Polyphenolics from mango (Mangifera indica L.) suppress breast cancer ductal carcinoma in situ proliferation through activation of AMPK pathway and suppression of mTOR in athymic nude mice. (oregonstate.edu)
  • Weaning is a critical period in lambs because they only receive milk from their mothers and the microbial population begins to establish. (degruyter.com)
  • Conclusion: During the early stages of helminth infection SOCS3 may be blocking proliferation as suggested by data from susceptible mice and preliminary knockout experiments. (lancs.ac.uk)
  • Iron is an essential nutrient in many cellular processes and therefore required for microbial proliferation and virulence. (bruker.com)
  • Following the ban on antibiotic use in ruminants and concerns about food safety, the feed industry has become more interested in direct-fed microbial (DFM) to improve animal performance [ 3 ]. (degruyter.com)
  • Other methods used to preserve fish and fish products include ikejime method of fish slaughter the control of temperature using ice, refrigeration or freezing the control of water activity by drying, salting, smoking or freeze-drying the physical control of microbial loads through microwave heating or ionizing irradiation the chemical control of microbial loads by adding acids oxygen deprivation, such as vacuum packing. (wikipedia.org)
  • In certain predisposed individuals, recurrent trauma may lead to the alteration of tissue antigens or ingress of unknown factors (eg, viral particles, toxic microbial products), which result in a hypersensitivity or allergic reaction. (medscape.com)
  • Basalt-hosted systems support a vast, hot and diverse microbial biosphere, in contrast to serpentinizing systems, which sustain more limited microbial communities primarily dominated by methane-metabolizing archaea. (nature.com)
  • Here we provide evidence for the existence of microbial communities in ~40° to 60°C sediment associated with lignite coal beds at ~1.5 to 2.5 km below the seafloor in the Pacific Ocean off Japan. (darkenergybiosphere.org)
  • iii) an assessment of the microbial communities associated with algae using new-generation sequencing. (ualg.pt)
  • In contrast, high-pH serpentinizing hydrothermal systems harbour a more limited microbial community consisting primarily of methane-metabolizing archaea. (nature.com)
  • During the earliest Triassic microbial mats flourished in the photic zones of marginal seas, generating widespread microbialites. (lu.se)
  • The magnitude of the shift at that time records a combination of changes in the global carbon cycle that were enhanced by the local increase in microbial activity, possibly also involving cyanobacterial proliferation. (lu.se)
  • The results presented here show that Neotethyan microbial buildups record a unique faunal association due to the presence of keratose sponges, while the Palaeotethyan buildups have a higher proportion of molluscs and the foraminifera Earlandia. (lu.se)
  • In presence of exogenous costimulation (anti-CD28, 5 g/ml), the TCR transmission strength required to result in maximum proliferation was 3 times lower for IMACS-CD4+ compared to IMACS/FACS-CD4+ (Number 5C). (mingsheng88.org)
  • We found that microbial dysregulation in infancy may trigger or accelerate JIA development. (cdc.gov)
  • The relationship between this global ID and the proliferation status will be tested. (ualg.pt)
  • In our group we study the eco-physiology and adaptation of nuisance cyanobacteria, in order to better understand and predict their proliferation in changing lakes. (unige.ch)
  • We also study ecosystem changes, and the negative consequences of the proliferation of the cyanobacteria for the provision of ecosystem services like the provision of drinking water, collecting seafood and recreation. (unige.ch)
  • Given the prominence of basaltic lava on Earth and Mars, microbial life could be habitable where subsurface basaltic rocks interact with liquid water. (darkenergybiosphere.org)
  • Macroalgae proliferations in tropical and subtropical coastal ecosystems represent a serious threat to marine biodiversity, in particular in coral reefs. (ualg.pt)
  • Microbial methanogenesis was indicated by the isotopic compositions of methane and carbon dioxide, biomarkers, cultivation data, and gas compositions. (darkenergybiosphere.org)