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  • lipid
  • The difficulty filling all the volume of the interior of a bilayer, while accommodating the area per head group forced on the molecule by the hydration of the lipid head group, leads to the formation of the micelle. (wikipedia.org)
  • The integral membrane enzyme diacylglycerol kinase (DAGK) has long been thought to require the presence of lipid as an obligate 'cofactor' in order to be catalytically viable in micelles. (mendeley.com)
  • These results highlight the fact that some integral membrane proteins can maintain native-like properties in lipid-free detergent micelles and also suggest that C(14)-based detergents may be worthy of more widespread use in studies of membrane proteins. (mendeley.com)
  • Why is it that things like phosphlipids and glycosphingolipids (like sphingomyelin and glycosphingolipids) form lipid bilayers when theyre exposed to water, whereas some things form micelles instead? (biology-online.org)
  • Controlling lipid micelle stability using oligonucleotide headgroups. (nih.gov)
  • We have engineered serum stabilized micelles using short quadruplex forming oligonucleotide extensions as the lipid headgroup. (nih.gov)
  • Bile acids form micelles which facilitate lipid digestion. (wikipedia.org)
  • concentrations
  • The field dependent spin-lattice relaxation rates were measured for Larmor frequencies ranging from 0.1 to 40 MHz and for two micelle concentrations at three temperatures (T=10,15,20oC). (diva-portal.org)
  • Furthermore, in vitro cell experiments demonstrated that fluorescently labeled micelles were successfully taken up by HeLa cells while cell viability remained high even at high micelle concentrations. (wur.nl)
  • nanoscale
  • Nanowerk News ) A team of researchers from New York University has engineered nanoscale protein micelles capable of both delivering chemotherapeutic drugs and of being tracked by magnetic resonance imaging (MRI). (nanowerk.com)
  • Her research paper, "Protein Engineered Nanoscale Micelles for Dynamic Magnetic Resonance and Therapeutic Drug Delivery," was published in the American Chemical Society journal ACS Nano ( 'Protein-Engineered Nanoscale Micelles for Dynamic 19 F Magnetic Resonance and Therapeutic Drug Delivery' ). (nanowerk.com)
  • small clusters
  • The proteins are held together by small clusters of calcium phosphate, the micelle also contains lipase, citrate, minor ions, and plasmin enzymes, along with entrapped milk serum. (wikipedia.org)
  • SAXS
  • B) Experimental SAXS profiles of DSPE-PEG, diC18-UGGGU, and diC18-UUUUU micelles each at 2 mg/mL, from top to bottom, and fitted profiles from ellipsoid model fits (red lines). (nih.gov)
  • Typical time evolution of absolute SAXS intensities upon rapid mixing of SDS micelles (weight 1%) and 2 M NaCl solution. (esrf.eu)
  • Quantitative analysis of the SAXS data in terms of a core-shell model yields the shape as well as the average size parameters of the micelles. (esrf.eu)
  • At higher salt concentration (1 M), the SAXS data are best described by a linear combination of ellipsoidal and worm-like micelles. (esrf.eu)
  • Concomitantly, the contour length of worm-like micelles ( L ave ) increases linearly as indicated in (c) and finally exceeds the resolution limit of the SAXS configuration. (esrf.eu)
  • Particle
  • When encapsulating hydrophobes in this way it is important to ensure the particle size is appropriate for the PEG backbone being utilized, as the number of PEG mer units (generally with a MW of 6K or 10K Daltons) determines the maximum particle size that can be successfully contained at the core of the micelle. (wikipedia.org)
  • compositions
  • Therefore, here we provide depth-dependent membrane and micelle compositions averaged over MD simulations carried out in our group. (tuhh.de)
  • partially
  • Although the closest counterions partially mask a charged micelle (by up to 90%), the effects of micelle charge affect the structure of the surrounding solvent at appreciable distances from the micelle. (wikipedia.org)
  • micelles Emulsified droplets of partially hydrolysed lipids, small enough to be absorbed across the intestinal mucosa. (encyclopedia.com)
  • Relaxation
  • The present findings demonstrate that cinnamaldehyde-loaded and poly(cinnamaldehyde) micelles possess vasodilator properties, but that the mechanism underlying the relaxation that they cause differs from that of cinnamaldehyde, and thus could be used both to relieve coronary vasospasm and for therapeutic drug delivery. (dovepress.com)
  • formation
  • Addition of antisense oligonucleotides that disrupt G-quadruplex formation results in micelle destabilization and cargo release. (nih.gov)
  • The upturn of intensity at low Q values indicates the formation of worm-like micelles. (esrf.eu)
  • hydrocarbon
  • For example, the micelles are, by nature, spatially heterogeneous with a hydrocarbon, nearly anhydrous core and a highly solvated, polar head group. (wikipedia.org)
  • oligonucleotides
  • Using antisense oligonucleotides we demonstrated that disruption of the quadruplex leads to micelle destabilization and cargo release. (nih.gov)
  • Micelle destabilization using antisense oligonucleotides. (nih.gov)
  • size
  • The micelles showed a small size (30 nm) and high loading capacity (16.0 ± 0.1%) for paclitaxel and released paclitaxel for more than ten days. (rsc.org)
  • addition
  • In addition, initial studies showed that PDT performed with silica micelles containing quantum dots and phthalocyanine could kill cancer cells. (photonics.com)
  • The addition of micelles to the mobile phase introduces a third phase into which the solutes may partition. (wikipedia.org)