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  • nude
  • When given for a period of 2 weeks (20 mg/kg/day, 3×/week), AQ-101 inhibited development of ALL in nude or SCID mice with a human ALL xenograft and achieved cure by the end of the 5-month experiment. (aacrjournals.org)
  • Growth
  • Apoptosis Induction in Primary Human Colorectal Cancer Cell Lines and Retarded Tumor Growth in SCID Mice by Sulforaphane," Evidence-Based Complementary and Alternative Medicine , vol. 2012, Article ID 415231, 13 pages, 2012. (hindawi.com)
  • intestinal
  • In this study, we show that intestinal inflammation is characterized by a 15-fold increase in the number of CD134L + (OX40L + )-activated DC in the mesenteric lymph nodes (MLNs) compared with BALB/c mice. (jimmunol.org)
  • absence
  • These data suggest that downregulation of innate immunity in SCID mice in the absence of B- and T-cell responses leads to an exacerbation of joint inflammation. (prohealth.com)
  • Infection
  • The injection of HIV into hu-PBL-SCID mice at 2 h after reconstitution resulted in a generalized and productive HIV infection of the xenochimeras. (mysciencework.com)
  • injection
  • Mice were euthanized 1 day, 6 months and 8 months after intravitreal injection. (arvojournals.org)
  • At 2 to 24 h after the intraperitoneal injection into SCID mice, there was a clear-cut increase in the percentage of hu-PBL expressing early activation markers (CD69), concomitant with the release of soluble intercellular adhesion molecule-1 (sICAM-1) and the soluble interleukin-2 receptor (sIL-2R) and with the accumulation of mRNAs for a number of human cytokines. (mysciencework.com)
  • indicate
  • Second, studies of parabiotic mice indicate that there is relatively little recirculation of SI-IEL ( 24 ). (jimmunol.org)
  • cell
  • In all H. pylori -infected mice, gastric CD4 + cell scores were increased, compared with scores for uninfected controls. (ingentaconnect.com)
  • For example, in mice, SI-IEL as a group constitutively express activation Ags such as CD69 ( 4 , 5 ) and a unique α E β 7 integrin ( 6 , 7 ), and they lack expression of molecules such as CD2, which characterize most other T cell populations ( 4 , 8 ). (jimmunol.org)
  • T-cell dysfunctions in hu-PBL-SCID mice infected with human im. (mysciencework.com)
  • therapeutic
  • In the present study, we evaluated the cancer-inhibiting mechanism of AQ-101 and tested the therapeutic potential of this compound for treating cancer in mice. (aacrjournals.org)
  • upon
  • Upon an intranasal immunization of M-protein and cholera toxin to these mice, M-protein specific human IgA antibody titers in nasal washings were higher than those of mice without intranasal challenge of M-proteins. (nii.ac.jp)
  • months
  • Among mice followed for 8 months, electroretinography (ERG) was performed on both eyes just prior to euthanization. (arvojournals.org)