One of the first INBRED MOUSE STRAINS to be sequenced. (uchicago.edu)
Fine mapping of a major QTL influencing morphine preference in C57BL/6 and DBA/2 mice using congenic strains. (jefferson.edu)
This Ab could induce SLE in naive mice of different prone strains (2). (cancercurehere.com)
pCDR3 and pCDR1 had been been shown to be immunodominant T-cell epitopes in BALB/c and SJL mouse strains, respectively, and induced a light SLE-like disease in responder mice (7). (cancercurehere.com)
such as for example and continues to be examined using several pets contaminated or normally experimentally, and Helicobacter an infection continues to be discovered to induce chronic energetic hepatitis, biliary and hepatocellular tract carcinomas, typhlocolitis, and decrease colon cancer in susceptible strains of inbred and Fluopyram engineered mice[29-39] genetically. (baxkyardgardener.com)
C57BL3
Mice, Inbred C57BL" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (uchicago.edu)
Below are the most recent publications written about "Mice, Inbred C57BL" by people in Profiles. (uchicago.edu)
C57BL/6 mouse splenocytes were stained with CD45R (B220) Monoclonal Antibody, FITC (Product # 11-0452-82) and 0.25 µg of Rat IgG2b kappa Isotype Control, Super Bright 600 (Product # 63-4031-82) (left) or 0.25 µg of CD3 Monoclonal Antibody, Super Bright 600 (right). (thermofisher.com)
Cystic2
Cftr-/- mice showed a higher expression of Muc6 at both protein and RNA levels compared with their control Cftr+/+ littermates suggesting that as in the human disease, Muc6 may contribute to the formation of materials that block pancreatic acini and ducts in mouse models of cystic fibrosis. (ox.ac.uk)
The rabbit anti-mouse Muc6 polyclonal antibody seems highly specific to the mouse mucin and will be useful to study pancreatic pathology in cystic fibrosis. (ox.ac.uk)
Genetically1
Here, the great strengths are derived from the very refined use of inbred and genetically manipulated mice under controlled conditions that negate environmental variation. (clinical-research-informatics.com)
Antibody6
The characterization of the first anti-mouse Muc6 antibody shows an increased expression of the mucin in pancreatic tissue of Cftr-knockout mice. (ox.ac.uk)
In order to further study Muc6 in mice, our aims were to obtain a specific Muc6 antibody, to validate it and to test it in Cftr deficient mice. (ox.ac.uk)
Kallikrein genes are associated with lupus and glomerular basement membrane-specific antibody-induced nephritis in mice and humans. (ouhsc.edu)
Description: The 17A2 monoclonal antibody reacts with the mouse CD3 complex. (thermofisher.com)
Applications Tested: This 17A2 antibody has been tested by flow cytometric analysis of mouse splenocytes. (thermofisher.com)
Large antibody titers correlate with low colony forming devices (CFUs) of UPEC following transurethral challenge of vaccinated mice. (morainetownshipdems.org)
This strain is commonly used as genetic background for transgenic mouse models. (uchicago.edu)
An inbred strain of mouse that is widely used in BIOMEDICAL RESEARCH . (nih.gov)
Of the 5379 expected proteins in prototype UPEC strain CFT073, only six proteins met all of our founded criteria: (1) surface exposure (expected and shown), (2) induction during growth in human being urine, (3) high manifestation in experimentally infected mice Minocycline hydrochloride and (4) high manifestation in ladies with UTI, (5) immunogenicity, and (6) pathogen-specificity. (morainetownshipdems.org)
Rats1
Animal models (e.g., mice, rats, zebrafish and others) are sufficiently like humans in their anatomy, physiology or response to a pathogen that researchers can extrapolate the results of animal model studies to better understand human physiology and disease. (genome.gov)
Neonatal mice1
The CDR1-structured peptide was also proven to prevent auto-Ab creation in BALB/c neonatal mice which were immunized afterwards with NGFR either pCDR1 or the pathogenic auto-Ab (7). (cancercurehere.com)
Syngeneic2
Single CAR-T cell treatment controls disseminated ovarian cancer in a syngeneic mouse model. (uchicago.edu)
Furthermore, T-cell lines particular to the individual anti-DNA 16/6Id+ mAb had been been shown to be with the capacity of inducing experimental SLE in syngeneic receiver mice indicating the function of T cells in the condition (5). (cancercurehere.com)
Transgenic1
Food-associated estrogenic compounds induce estrogen receptor-mediated luciferase gene expression in transgenic male mice. (knaw.nl)
Allele3
To block apoptosis, we conditionally deleted one allele of p53 in Ncadk.i. mice and observed a temporal rescue of alveolar morphology and function. (biomedcentral.com)
Additionally, it will consider how immunological measurement, interpreted in the light of paradigms from laboratory mouse immunology, can define individual variation relevant to ecological and epidemiological studies of infectious disease in the natural environment LY2090314 1, 6. (clinical-research-informatics.com)
Experimental7
Amelioration of the medical manifestations of an already founded experimental SLE correlated with a dramatic decrease in TNF secretion, elevated levels of TGF, and immunomodulation of the Th1 and Th2 type cytokines to levels close to those observed in healthy mice. (cancercurehere.com)
Experimental SLE may also be induced in mice after their immunization with the murine anti-16/6Id mAb (3) or a murine anti-DNA 16/6Id+ mAb, 5G12 (4), recommending the need for the 16/6Id network in the condition. (cancercurehere.com)
Experimental SLE, although induced in mice that develop no symptoms of SLE normally, was found to talk about features using the SLE style of (NZBxNZW)F1 mice, which develop the condition spontaneously. (cancercurehere.com)
Hence, sequencing from the adjustable locations coding for the large and light stores of anti-DNA mAb isolated from mice suffering from experimental SLE present high homology using the adjustable parts of anti-DNA mAb isolated order CB-7598 from (NZBxNZW)F1 mice (6). (cancercurehere.com)
A reduction in Th1-type (IL-2, INF) cytokines was noticed when order CB-7598 mice had been treated for experimental SLE avoidance, whereas the amelioration of disease manifestations in the procedure protocol was connected with a design of Th1 and Th2 cytokines very similar to that seen in healthful mice. (cancercurehere.com)
A substantial down-regulation from the proinflammatory cytokine TNF and an up-regulated secretion from the immunosuppressive cytokine TGF was showed in mice treated for either the avoidance or immunomodulation of experimental SLE. (cancercurehere.com)
Each of these themes will be considered in turn and then the reasons why nonmodel rodents (species excluding M.?domesticusand studies in natural populations tracking the effects of environmental variables using manipulative experimental or observational approaches (see for example, the solid wood mouse case study below), or through transplantation of naturally occurring lineages to (and monitoring of the changes occurring in) experimentally manipulated anthropogenic environments. (clinical-research-informatics.com)
Gene2
Analysis of a quantitative trait locus for seizure susceptibility in mice using bacterial artificial chromosome-mediated gene transfer. (jefferson.edu)
Identification of five mouse mu-opioid receptor (MOR) gene (Oprm1) splice variants containing a newly identified alternatively spliced exon. (jefferson.edu)
Monoclonal1
Further, the CDR-based peptides inhibited the priming of lymph-node cells (LNC) of mice immunized using the same peptides or using the monoclonal anti-DNA 16/6Id+ Abs of either mouse or individual origins. (cancercurehere.com)
Tumors2
Concordantly, 55% of Ncadk.i. mice harboring a heterozygous p53 deletion developed malignant and invasive tumors. (biomedcentral.com)
Thus, we provide a new mouse model to investigate the molecular mechanisms of fibrocystic mastopathy and the transition from benign to malignant tumors. (biomedcentral.com)
Peptide2
A polyclonal serum named CP4 was isolated from a rabbit immunized by a mouse Muc6 peptide. (ox.ac.uk)
In today's report, the power from the CDR1-structured peptide to immunomodulate SLE induced in BALB/c mice was examined. (cancercurehere.com)
Deletion1
Foxe1 Deletion in the Adult Mouse Is Associated With Increased Thyroidal Mast Cells and Hypothyroidism. (uchicago.edu)
Specific1
We shown for all four vaccine antigens that antigen-specific serum IgG represents a strong correlate of safety in vaccinated mice. (morainetownshipdems.org)
Mechanisms1
Immunoglobulin G subclasses confer protection against Staphylococcus aureus bloodstream dissemination through distinct mechanisms in mouse models. (uchicago.edu)
Liver1
may set up a chronic an infection in A/JCr mice by colonizing the low colon and, sporadically, the liver organ, in the bile canaliculi[40] particularly. (baxkyardgardener.com)
Model2
Retinal ganglion cell protection by 17-beta-estradiol in a mouse model of inherited glaucoma. (ouhsc.edu)
We recently addressed the question of interchangeability of the two cadherins by generating a mouse model in which N-cad cDNA was introduced into the E-cad locus. (biomedcentral.com)
Levels1
Protein levels of sAPPα and sAPPβ are measured by western blot assay in cerebral cortex of 12-month-old AD mice with different treatments (RSG and GW9662). (medchemexpress.com)
Shows1
This graph shows the total number of publications written about "Mice, Inbred DBA" by people in this website by year, and whether "Mice, Inbred DBA" was a major or minor topic of these publications. (ouhsc.edu)
Analysis of mouse1
Systems genetics analysis of mouse chondrocyte differentiation. (jefferson.edu)
Treatment1
PPARγ level is determined by IF assay in 3×Tg-AD mice, 3×Tg-AD mice with RSG treatment, 3×Tg-AD-KO mice, 3×Tg-AD-KO mice with GW9662 stimulation. (medchemexpress.com)