• These data demonstrate that NK cells and NKT cells are the most abundant IFN-gamma-producing cells in the mouse spleen after LPS challenge and that IL-10 and IL-12 are key functional regulators of LPS-induced IFN-gamma production. (labome.org)
  • A suppressive effect of SV influenza virus on WV vaccine was also observed in an in vitro antibody-forming system, using primed mouse spleen cells. (elsevier.com)
  • Circadian rhythms of locomotion (wheel-running activity) in 12 inbred mouse strains were recorded for interstrain differences in tau DD, the endogenous (free-running) period of the circadian pacemaker measured in constant environmental darkness. (umassmed.edu)
  • The results indicate that 1 or more genetic loci influence the value of tau DD, and a large (50 min) difference in mean tau DD between 2 of the strains, BALB/cByJ and C57BL/6J, allowed further characterization of the origins and inheritance of the polymorphic expression of this circadian pacemaker property. (umassmed.edu)
  • Further study of inherited differences in the BALB/c and C57BL/6 strains may be a useful noninvasive experimental approach for investigation of the neurobiological substrates of circadian rhythmicity. (umassmed.edu)
  • however, the mutant and wild-type strains had similar LD50 values for both orally and intraperitoneally infected mice. (nih.gov)
  • Haeberle H, Kuziel W, Dieterich H, Casola A, Gatalica Z, Garofalo R. Inducible expression of inflammatory chemokines in respiratory syncytial virus-infected mice: role of MIP-1alpha in lung pathology. (labome.org)
  • Consequently, we investigated the effects of (R)-, (S)- and racemic-albuterol on airway smooth muscle cell (SMC) contraction and Ca(2+) signaling in mouse lung slices with phase-contrast and confocal microscopy. (umassmed.edu)
  • To examine the pathological consequences of loss of responsiveness to Th2 cytokines, we compared lesion evolution in IL-4Rα(-/-) and wild type (WT) BALB/c mice immunized with PLP180-199 and investigated how altering the magnitude of the antigen-specific autoimmune response in this model affected the pathology. (edu.au)
  • The cell-mediated immune function of cold-adapted BALB/c inbred mice was studied in experiments of splenic lymphocyte blastogenesis, indicated by tritium-labeled deoxythymidine incorporation and SDS-PAGE autoradiography of synthetic proteins in lymphocytes. (semanticscholar.org)
  • Results shown are from two different experiments with five mice per group for each experiment. (nih.gov)
  • In a series of experiments performed in hamsters and mice, administration of mixtures of detergent-disrupted (SV) influenza A X49 (H3N2) virus and inactivated X49 whole virus (WV) vaccine induced lower serum antibody titres than equivalent or lower doses of WV vaccine alone. (elsevier.com)
  • METHODS: A total of 110 mice were used in three pilot studies (1-3) and two experiments (A, B). Due to the high complication rates, the analgesic regimen and surgical techniques were changed throughout the pilot studies/experiments. (forskningsdatabasen.dk)
  • Additionally, although only approximately 75% of WT mice developed clinical disease, lesions were observed in 100% of the mice, principally in the cerebellum, mid-brain and cerebral hemispheres, and lesion load increased with increasing pro-inflammatory cytokine production. (edu.au)
  • The aim of this study was to develop an optimal model of clinical colon anastomotic leakage in a technically insufficient anastomosis in the mouse. (forskningsdatabasen.dk)
  • Bars show mean Penh (± SEM) of groups of five mice before (gray bars) or after (white bars) methacholine stimulation. (nih.gov)
  • Each bar represents the mean (± SEM) concentration in groups of five mice on day 4. (nih.gov)
  • We recently described a novel marker combination (CD127 and CD62L) to identify all three major CD8(+) T cell subsets in mice infected with Listeria monocytogenes (L.m. (curehunter.com)
  • For blocking studies, mice were injected daily with 100 μg per mouse polyclonal rabbit antieotaxin Abs 7 or polyclonal rabbit anti-murine MDC 13 30 min before OVA challenge. (nih.gov)
  • Mice immunized intranasally with J5dLPS/OMP exhibited protective immunity to intratracheal challenge with the live vaccine strain, as well as the highly-virulent SchuS4 strain, of F. tularensis. (biomedsearch.com)
  • Disruption of this gene in mice resulted in abnormal embryonic blood vessel formation. (cancerindex.org)