Germ CellsMice, TransgenicGerm-Line MutationOogenesisCaenorhabditis elegansCaenorhabditis elegans ProteinsMicronucleus, GermlineDNA Mutational AnalysisDrosophila ProteinsMutationPedigreeHamartoma Syndrome, MultipleNeoplastic Syndromes, HereditaryColorectal Neoplasms, Hereditary NonpolyposisImmunoglobulin Variable RegionAnimals, Genetically ModifiedDrosophila melanogasterBase SequenceGenes, BRCA1Molecular Sequence DataStem CellsDrosophilaGenetic Predisposition to DiseaseGenes, ImmunoglobulinAllelesImmunoglobulin Heavy ChainsLi-Fraumeni SyndromeParagangliomaOvaryPhenotypeMutS Homolog 2 ProteinAdenomatous Polyposis ColiArgonaute ProteinsGene Expression Regulation, DevelopmentalGenes, BRCA2SpermatogenesisBRCA2 ProteinGenetic TestingMosaicismGonadsSpermatogoniaAntibody DiversityMeiosisDisorders of Sex DevelopmentTestisSex Determination ProcessesExonsLoss of Heterozygosity