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  • congenital heart d
  • In this current study, with the repair of congenital heart defects in our Id knockout embryos, we observed that the stem cells provided normal signals to themselves and also to their neighbor cells to correct the organ as a whole," explained Diego Fraidenraich, Ph.D., the study's lead author. (innovations-report.com)
  • transgenic
  • MELVILLE, N.Y. -- From a background of blackness emerges a peaceful image of bright red and green -- a double transgenic mouse embryo -- this year's winning entry in the Nikon Small World Photomicrography Competition. (imaging-resource.com)
  • To demonstrate the potential value of high-throughput phenotyping for major organ compartments and tissue structures of younger embryos, they used transgenic mice with complex malformations of the developing brain and upper spinal cord. (photonics.com)
  • glucose
  • Lawitts, J. A. and Biggers, J. D. (1992) Joint effects of sodium chloride, glutamine, and glucose in mouse preimplantation embryo culture media. (springer.com)
  • Carbon dioxide and lactate production from [ 14 C]glucose were measured for post-implantation mouse embryos aged 6 to 9½ days post coitum in static cultures with a defined medium. (biologists.org)
  • We used high-glucose loaded 2-cell stage mouse embryos as a model and took advantage of single-cell RNA sequencing technology to analyze the transcriptome of the model with or without ZGW. (hindawi.com)
  • High glucose can downregulate genes in the ribosome pathway, while ZGW can reverse this inhibition and as a result prevent embryo cell death caused by high glucose. (hindawi.com)
  • The reversion of inhibition of ribosome pathway and regulation of mitochondrial energy metabolism are main effects of ZGW on high-glucose loaded embryos. (hindawi.com)
  • aggregates
  • Peter Baillie-Johnson was working on the generation of elongating gastruloids to mimic the first stages of axial elongation in the mouse embryo, but was limited by aggregates adhering to the surface of culture plates. (biologists.org)
  • blastocysts
  • Some of those images have already been beamed back to Earth, and show that the initial two-cell embryos grew into fully developed blastocysts (the name given to embryos before they implant onto the wall of the uterus) over the course of 80 hours in space. (rt.com)
  • Cell
  • The researchers used a 1 percent solution of osmium tetroxide to stain the embryos' cell membranes and found that it was best suited for gestational ages with limited epidermal layers. (photonics.com)
  • The ability of two embryonal carcinoma (EC) cell lines, F9 and PCI3, to aggregate with preimplantation 8-cell mouse embryos is described. (biologists.org)
  • embryos obtained from F1 hybrid mice do not exhibit the two-cell block. (springer.com)
  • This would indicate that the PGC lineage in the mouse is set aside at least as early as 7 dpc, possibly as one of the first 'mesodermal' cell types to emerge, and that its differentiation, as expressed by ALP activity, is gradual. (biologists.org)
  • This report describes the establishment directly from normal preimplantation mouse embryos of a cell line that forms teratocarcinomas when injected into mice. (pnas.org)
  • When the team studied the mosaic mice, Kaestner says, they found that "the intestine essentially forgets that it is supposed to be intestine and adopts a new cell fate. (pennmedicine.org)
  • proteins
  • As fertilized mouse eggs develop into embryos and maternal proteins are eliminated, the degradative process of autophagy is required for proper growth. (sciencemag.org)
  • Thus
  • Thus, functional peculiarities of early embryos allow studying the nuclei under different transcriptional conditions without artificial inhibitors. (hindawi.com)
  • methodologies
  • Two attachment methodologies, rolling and pushpin, which allow two entirely different levels of applied forces to attach the chips to living embryos, are evaluated. (rsc.org)
  • neural
  • Disruption of mouse Tulp3 results in morphological defects in the embryonic craniofacial regions, the spinal neural tube and the limbs. (nih.gov)
  • tissue
  • Embryos from which the cluster area has been removed at the 7-day stage are devoid of PGCs after culture for 48 h, whereas the excised tissue is rich in PGCs. (biologists.org)