Mice against invasive infection streptococcus pneumoniae. Medical search. Frequent questions

Streptococcus pneumoniae is an important human pathogen responsible for community acquired pneumonia, as well as meningitis, sepsis and milder infections like otitis media [ 1 ]. (biomedcentral.com)
Streptococcus pneumoniae is a human pathogen that is responsible for causing pneumonia, otitis media, meningitis, and other infectious diseases. (mdpi.com)
This sequence of events is then tested in mouse models of pneumonia and meningitis. (stjude.org)
Globally, about 3 million deaths annually are due to Streptococcus pneumoniae , a bacterium that causes otitis media, pneumonia, meningitis or bacteremia. (viin.org.au)
However, hospitalisation of especially young children and the elderly suffering from influenza is often necessary to treat secondary bacterial infections causing pneumonia. (viin.org.au)
But from there, S. pneumoniae can spread into the lungs, blood and brain, or more locally into the ear, to cause diseases such as pneumonia, bacteremia , meningitis and otitis media (middle ear inflammation). (nationalinterest.org)
Pneumonia, sepsis, meningitis, and empyema due to Streptococcus pneumoniae is a major cause of morbidity and mortality. (biomedcentral.com)
We provide a systemic overview of genetic variants associated with susceptibility, phenotype and outcome of community acquired pneumococcal pneumonia (CAP) and invasive pneumococcal disease (IPD). (biomedcentral.com)
Invasive pneumococcal disease (IPD) is an infection confirmed by the isolation of Streptococcus pneumoniae from a normally sterile site, while non-invasive pneumococcal disease includes sinusitis, mastoiditis, acute otitis media, and community-acquired pneumonia (CAP). (biomedcentral.com)
iGAS stands for invasive group A strep and occurs when the strep A bacteria enters areas of the body where it doesn't normally go, such as the blood or the lungs, where it can cause sepsis or pneumonia. (madeformums.com)
It is a case of acute lower respiratory tract infection, probably lobar pneumonia. (microrao.com)
Pneumonia can be caused by bacteria such as Streptococcus pneumoniae (pneumococcus), Hemophilus influenzae, Klebsiella pneumoniae, Staphylococcus aureus. (microrao.com)
Mycoplasma pneumoniae is known to cause primary atypical pneumonia. (microrao.com)
Carvalhaes CG, Sader HS, Rhomberg PR and Mendes RE: Tedizolid activity against a multicentre worldwide collection of Staphylococcus aureus and Streptococcus pneumoniae recovered from patients with pneumonia (2017-2019). (spandidos-publications.com)

Nasopharyngeal colonization occurs in biofilms and precedes infection. (lu.se)
A Novel Heme Transporter from the Energy Coupling Factor Family Is Vital for Group A Streptococcus Colonization and Infections. (gsu.edu)
NP colonization results in a robust immune response that protects against invasive infections. (umassmed.edu)
A paper has been circulating with an eye-catching title: 'Live Attenuated Influenza Vaccine Enhances Colonization of Streptococcus pneumoniae and Staphylococcus aureus in Mice. (euronews.com)
Colonization followed by influenza coinfection led to a synergistic type I IFN response, resulting in increased density of colonizing bacteria and susceptibility to invasive infection. (nih.gov)
Indeed, the increased colonization associated with concurrent influenza virus infection was not observed in mice lacking Nod2 or the type I IFN receptor, or in mice challenged with pneumococci lacking pneumolysin. (nih.gov)
We therefore propose that the synergistic stimulation of type I IFN production during concurrent influenza virus and pneumococcal infection leads to increased bacterial colonization and suggest that this may contribute to the higher rates of disease associated with coinfection in humans. (nih.gov)
Dr. Biswas's research projects focused on the reduction of pre- and post-harvest levels of colonization and contamination these foodborne bacterial pathogens in foods specifically meat and meat products and development of vaccines that prevent colonization of animals by E. coli O157, C. jejuni and Salmonella enterica species which may reduce human gastrointestinal infections. (umd.edu)
Certain persons with pneumococcal colonization might develop invasive pneumococcal disease (IPD) ( 2 ). (cdc.gov)

As a consequence, the lower airways become persistently infected, where up to 50% of COPD patients are chronically colonized with potentially pathogenic bacteria including Haemophilus influenzae, Streptococcus pneumoniae and Moraxella catarrhalis ( 5 , 6 ). (frontiersin.org)
The introduction of Haemophilus influenzae type b conjugate vaccines during the 1990s was followed by dramatic decreases both in the incidence of Haemophilus influenzae type b related invasive disease and in nasopharyngeal carriage of the organism. (bmj.com)
Haemophilus influenzae type b, Streptococcus pneumoniae , and Neisseria meningitidis colonise the mucosa of the human upper respiratory tract along with other opportunistic pathogens and commensal bacteria. (bmj.com)
Changes in the incidence of invasive disease due to Streptococcus pneumoniae, Haemophilus influenzae, and Neisseria meningitidis during the COVID-19 pandemic in 26 countries and territories in the Invasive Respiratory Infection Surveillance Initiative: a prospective analysis of surveillance data. (szu.cz)
Bacteremic Haemophilus influenzae genitourinary tract infections in adults. (microbiologyresearch.org)
Nosocomial spread of Haemophilus influenzae type b infection documented by outer membrane protein subtype analysis. (microbiologyresearch.org)
A comparative study of the virulence of smooth, rough and respiratory strains of Haemophilus influenzae as determined by infection of mice with mucin suspensions of the organisms. (microbiologyresearch.org)

Here, we show that coinfection of the upper respiratory tract of mice with influenza virus and pneumococcus leads to synergistic stimulation of type I IFNs and that this impairs the recruitment of macrophages, which are required for pneumococcal clearance, due to decreased production of the chemokine CCL2. (nih.gov)
Pneumococcus is not a common cause of neonatal infection in high-income countries, but a study of neonatal infections in South Asia identified pneumococcus as a culture-confirmed cause of neonatal sepsis almost as commonly as Streptococcus agalactiae (group B streptococcus) in infants 0-59 days of age [ 2 ]. (biomedcentral.com)
Streptococcus pneumoniae ) OR ( S. pneumoniae ) OR pneumococcal OR pneumococcus) AND (polymorphisms OR polymorphism OR (genetic variant) OR (genetic variants) OR (genetic association study) OR (single nucleotide polymorphism) OR (single nucleotide polymorphisms) OR SNP OR SNPs OR genotype OR genotypes) without language restrictions and with search date cut offs between Jan 1, 1983 and Jul 4, 2018. (biomedcentral.com)
Pneumococcal infections are caused by Streptococcus pneumoniae (pneumococcus), a gram-positive, facultative anaerobic bacterium. (cdc.gov)

We used whole-transcriptome shotgun sequencing (RNA-seq) to compare the S. pneumoniae transcriptome in biofilms, bacteria dispersed from biofilms after exposure to IAV, febrile-range temperature, or ATP, and planktonic cells grown at 37°C. Compared with biofilm. (lu.se)
We used whole-transcriptome shotgun sequencing (RNA-seq) to compare the S. pneumoniae transcriptome in biofilms, bacteria dispersed from biofilms after exposure to IAV, febrile-range temperature, or ATP, and planktonic cells grown at 37°C. Compared with biofilm bacteria, actively dispersed S. pneumoniae, which were more virulent in invasive disease, upregulated genes involved in carbohydrate metabolism. (lu.se)
Sixteen children have now died in Britain due to the Strep A bacteria, according to the UK Health Security Agency. (euronews.com)
However, the paper is not related to Strep A, as the two organisms mentioned are not Group A streptococcal bacteria. (euronews.com)
S. pneumoniae are encapsulated, nonsporulating, facultative anaerobic, lancet-shaped Gram-positive bacteria that reside in the human nasopharynx. (mdpi.com)
In fact, the keen ability of the deadly bacteria Streptococcus pneumoniae to use the plant-derived sugar raffinose may explain how it spreads through the human body . (nationalinterest.org)
S. pneumoniae is a bacteria that can quickly develop antibiotic resistance. (nationalinterest.org)
Using a cutting-edge sequencing technique during live mice infections, we discovered the difference in the rafR gene altered how both the mice and the bacteria responded to infection. (nationalinterest.org)
Treatments that prevent S. pneumoniae from spreading around the body may be better for preventing disease compared to simply inhibiting or killing the bacteria, as is current practice. (nationalinterest.org)
This underlying chronic infection leaves COPD patients particularly vulnerable to acute viral infections, which further destabilize host immunity to bacteria. (frontiersin.org)
This article reviews recent studies on mucosal immune responses induced by polysaccharide based vaccines and some protein vaccine antigens against several pathogenic nasopharyngeal bacteria, and discusses the mechanisms and functions of these immune responses that may help our understanding of mucosal immune responses to both immunisation and infection. (bmj.com)
It has long been recognised that serum antibodies to capsular PS of some bacteria including H influenzae type b, S pneumoniae , and N meningitidis are protective against invasive disease. (bmj.com)
Image: This illustration depicts a gram stained specimen under a microscope, with a number of Streptococcus pneumoniae bacteria (the small black dashes). (edu.au)
Group A streptococcus is a type of bacteria that is extremely common. (madeformums.com)
As we now mix as normal, there are many children who have not previously been exposed to infections, and so bacteria and viruses can easily spread. (madeformums.com)
In Europe and the US, Streptococcus pneumoniae is the leading cause but in Africa, enteric bacteria, such as Salmonella are most common. (biomedcentral.com)
Antimicrobial Resistance (AMR) is rampant among bacteria that cause healthcare- and community-acquired infections, driving up costs and increasing the difficulty of therapeutic management. (europa.eu)
The work package focusing on molecular studies generated new evidence about the changes effected by antibiotic therapy on commensal organisms or opportunistic pathogens in the oropharyngeal, nasal and gastro-intestinal flora and study AMR mechanisms and the dissemination of successful clones of fluoroquinolone-resistant, carbapenem-resistant or extended-spectrum beta-lactamase harboring Gram-negative bacteria, MRSA and fluoroquinolone-resistant viridans streptococci. (europa.eu)

Pneumococcal vaccines are vaccines against the bacterium Streptococcus pneumoniae. (wikipedia.org)
Pili were recently recognized in Streptococcus pneumoniae and implicated in the virulence of this bacterium, which led to the proposal of using these antigens in a future pneumococcal vaccine. (biomedcentral.com)

Carriage is asymptomatic but can be an antecedent to otitis media and invasive pneumococcal disease (IPD), usually attributable to a recently acquired serotype [ 9 ]. (biomedcentral.com)

The major focus of this research is the molecular pathogenesis of invasion and inflammation induced by Streptococcus pneumoniae, the leading invasive bacterial pathogen of children. (stjude.org)
Unfortunately, S. pneumoniae is a genetically diverse pathogen , which means it has many different strains. (nationalinterest.org)
A recent study revealed some interesting findings by comparing germ-free (GF) mice to mice with a normal microbiota (i.e., specific pathogen-free, SPF) animals [ 11 ] . (encyclopedia.pub)

However, there is no concrete evidence that shows that flu vaccines cause a higher susceptibility to Strep A. (euronews.com)
Pathological inflammation is worsened by chronic bacterial lung infections and susceptibility to recurrent acute exacerbations of COPD (AECOPD), typically caused by viral and/or bacterial respiratory pathogens. (frontiersin.org)
Another major consequence of susceptibility to infection is that people with underlying severe disease frequently develop acute exacerbations of COPD (AECOPD). (frontiersin.org)
This study suggests that E-cigarette vapour has the potential to increase susceptibility to pneumococcal infection. (ersjournals.com)
Bile solubility, inulin fermentation, optochin susceptibility, quellung reaction and mouse intraperitoneal inoculation may be done to differentiate pneumococci from viridans streptococci. (microrao.com)

To analyse the importance in virulence of three of these metalloproteinases, intranasal challenge of MF1 outbred mice was carried out using a range of infecting doses of wild type and knock-out pneumococcal mutant strains, in order to compare mice survival. (biomedcentral.com)
ii) ZmpC, only present in about 25% of pneumococcal strains, has a lower influence on virulence in mice. (biomedcentral.com)
New research published today in Nature Communications Biology by my colleagues and I circumvented these genetic diversity issues by studying closely related strains of S. pneumoniae . (nationalinterest.org)
In our previous research , two closely related strains of S. pneumoniae were isolated, one from the blood of a patient and another from the ear. (nationalinterest.org)
Notably, strains containing the rafR from the ear sample resulted in more neutrophils, an important immune cell, at the site of infection. (nationalinterest.org)
If this raffinose phenomenon proves to be widespread across S. pneumoniae strains, blocking their ability to use raffinose may prevent them from surviving in, and thus invading, the lungs. (nationalinterest.org)
Since invasive pneumococcal strains adhere to, and translocate across, respiratory tract epithelial cells, adhesion is a prerequisite for establishing pneumococcal disease [ 4 ]. (ersjournals.com)
A study of the population dynamics of strains of Hemophilus influenzae type b in combined infection with influenza C virus in embryonated eggs. (microbiologyresearch.org)

TMEM173 encodes MPYS/STING and is an innate immune sensor for cyclic dinucleotides (CDNs) playing a critical role in infection, inflammation, and cancer. (aai.org)
1. The function of secretory antibodies in protection of the mucosal surfaces against infection and inflammation. (viin.org.au)
Here, we review emerging mechanisms into why COPD patients are susceptible to chronic bacterial infections and highlight dysregulated inflammation and production of reactive oxygen species (ROS) as central causes. (frontiersin.org)

However, in many parts of Africa, especially in individuals who are malnourished, infected with malaria, or have sickle cell disease, the organism causes serious and potentially fatal systemic infections. (biomedcentral.com)

Invasive disease caused by group A strep- seasonal variation in acquisition of nasopharyngeal colo- tococci and group B streptococci was also assessed for nization also has been documented in children (6). (cdc.gov)
Streptococcus pneumoniae commonly resides asymptomatically in the nasopharyngeal (NP) cavity of healthy individuals but can cause life-threatening pulmonary and systemic infections, particularly in the elderly. (umassmed.edu)
Nicotine-containing E-cigarette vapour increased mouse nasal PAFR expression, and nasopharyngeal pneumococcal colonisation. (ersjournals.com)

These data help explain pneumococcal virulence after IAV infection and have important implications for studies of S. pneumoniae pathogenesis. (lu.se)
After a postdoctoral fellowship with Prof. June Scott at Emory University investigating the role of iron metabolism in the physiology and pathogenesis of Group A Streptococcus (GAS), Dr. Eichenbaum joined the Biology Graduate Faculty at GSU. (gsu.edu)
Thus, improved understanding of the pathogenesis of iNTS warrants urgency to provide new tools for preventive care of SCD in populations most afflicted by the infections. (biomedcentral.com)
Akitsu A, Kakuta S, Saijo S, Iwakura Y. Rag2-deficient IL-1 Receptor Antagonist-deficient Mice Are a Novel Colitis Model in Which Innate Lymphoid Cell-derived IL-17 Is Involved in the Pathogenesis. (chiba-u.ac.jp)

However, Strep A is treatable with antibiotics. (euronews.com)
Thankfully, strep A infections are treatable with antibiotics and it is rare that children become more seriously unwell. (madeformums.com)

Invasive non-typhoidal Salmonella in sickle cell disease in Africa: is increased gut permeability the missing link? (biomedcentral.com)
Since the portal of entry of non-typhoidal Salmonella into the systemic circulation is by way of the intestine, we argue that an increased gut permeability plays a vital role in the initiation of invasive non-typhoidal Salmonella in these patients. (biomedcentral.com)
Here, we will appraise the evidence supporting a breach in the intestinal barrier and propose the mechanisms for the increased risks for invasive non-typhoidal Salmonella infections in these individuals. (biomedcentral.com)
Although a typhoid fever/invasive non-Typhoidal Salmonella (iNTS) disease conjugate vaccine targeting S. enteritidis, S. typhimurium, and S. typhi is currently in Phase 1 clinical trials, prevention of Salmonella infections, particularly those by NTS, remains a major challenge. (biomedcentral.com)

When infecting mice lungs with S. pneumoniae through their nose, we found the blood sample remained in the lungs, causing invasive disease. (nationalinterest.org)
This research highlights how this single difference in the gene increased neutrophil levels during infection, preventing S. pneumoniae from causing invasive disease. (nationalinterest.org)

We determined the effect of vapour on oxidative stress-induced, PAFR-dependent pneumococcal adhesion to airway epithelial cells in vitro , and on pneumococcal colonisation in the mouse nasopharynx. (ersjournals.com)

Hemoglobin stimulates vigorous growth of Streptococcus pneumoniae and shapes the pathogen's global transcriptome. (gsu.edu)

Some patients get sepsis because of hospital-acquired infections. (ki.se)

The disease state is an outcome of the fungal pathogen's interactions with the host immunity, and therefore, it stands to reason that deep/invasive fungal diseases be amenable to immunotherapy. (onacademic.com)

Streptococcus pyogenes, Candida albicans and Candida krusei. (bvsalud.org)

Acute respiratory infection (ARI) surveillance was conducted from 0 to 6 months of age among 1060 infants of women randomized to one of four pre/post-partum vitamin D dose combinations or placebo. (biomedcentral.com)

In this study, we found that repeated NP exposure of mice to S. pneumoniae TIGR4 strain results in pneumococcal-specific Ab responses that protect against lethal lung challenge. (umassmed.edu)

Pneumococcal infection of the respiratory tract is often secondary to recent influenza virus infection and accounts for much of the morbidity and mortality during seasonal and pandemic influenza. (nih.gov)
Invasive pneumococcal disease is a major cause of infant morbidity and death worldwide. (biomedcentral.com)
Therefore, antifungal immunotherapy continues to be attractive as an adjunct to the currently available antifungal chemotherapy options for a number of reasons, including the fact that existing antifungal drugs, albeit largely effective, are not without limitations, and that morbidity and mortality associated with invasive mycoses are still unacceptably high. (onacademic.com)

Treatment of type-specific Hemophilus influenzae infections in infancy and childhood. (microbiologyresearch.org)
Experimental combined viral and bacterial infection (influenza C and Hemophilus influenzae type b) in embryonated eggs. (microbiologyresearch.org)

Streptococcus pneumoniae is a leading cause of infectious disease globally. (lu.se)

However, influenza A virus (IAV) infection releases virulent pneumococci from biofilms in vitro and in vivo. (lu.se)
At the time of writing this article, there is not any new evidence that this is a new or more virulent strain of group A strep. (madeformums.com)

The mHAQ mouse also does not respond to CDNs in vitro and in vivo. (aai.org)

On social media, especially TikTok, people have been making links between nasal flu vaccines given to children and the rise in Strep A infections this winter. (euronews.com)
Although Pneumococcal Conjugate Vaccines (PCVs) are available and have significantly reduced the rate of invasive pneumococcal diseases, there is still a need for new vaccines with unlimited serotype coverage, long-lasting protection, and lower cost to be developed. (mdpi.com)
Several new mucosal vaccines against respiratory infections are under development. (bmj.com)
Pneumococcal infections can be readily prevented with penicillin prophylaxis and the advent of pneumococcal conjugate vaccines has been a major breakthrough in disease prevention. (biomedcentral.com)

Characteristics of group B streptococcus isolated from infants with invasive infections: a population-based study in Japan. (chiba-u.ac.jp)

Obstructive bronchopulmonary aspergillosis is an uncommon manifestation of non-invasive aspergillosis seen in patients with AIDS . (radiopaedia.org)
Establishing rapid diagnoses of invasive aspergillosis (IA) is a priority tests that detect galactomannan and beta-D-glucan are available, but are technically cumbersome and rely on invasive sampling (blood or bronchoalveolar lavage). (onacademic.com)

In all geographic areas, invasive pneumococcal disease ty of a cellular receptor or the activity of the immune exhibited a distinct winter seasonality, including an response (7). (cdc.gov)
Surveillance for invasive pneumococcal disease was annual seasonal pattern that has been repeatedly docu- performed from January 1, 1996, through December 31, mented but never well explained. (cdc.gov)
These data suggest Iga, ZmpB and ZmpC as candidate surface proteins responsible for pneumococcal infection and potentially involved in distinct stages of pneumococcal disease. (biomedcentral.com)
Nonetheless, our research provides insight into how S. pneumoniae causes disease. (nationalinterest.org)
S. pneumoniae can stay in our nose and throats, where it does not cause disease. (nationalinterest.org)
PSERENADE TEAM, KRIZOVA, P. Changes in invasive pneumococcal disease caused by Streptococcus pneumoniae serotype 1 following introduction of PCV10 and PCV13: findings from the PSERENADE Project. (szu.cz)
The clinical features of invasive NTS (iNTS) are distinct from those of gastroenteritis or typhoid disease. (biomedcentral.com)
Japanese Invasive Disease Study Group. (chiba-u.ac.jp)

Cultures grew Streptococcus milleri and anaerobes (Prevotella species). (medscape.com)
People with poor oral hygiene, altered swallowing reflexes, or impaired consciousness are predisposed to infection by anaerobes due to aspiration of oral fluids. (microrao.com)

While infections caused by encapsulated bacterial agents are the most widely recognized cause of life threatening infections in SCD, specific species vary across geographic regions. (biomedcentral.com)

Fluconazole is commonly used to treat yeast infections of the mouth or throat. (ifemarketing.com)

Imaging of pulmonary infections. (radiopaedia.org)
We optimized a lateral flow dipstick assay using the galactofuranose-specific monoclonal antibody (mAb476), which recognizes urine antigens after Aspergillus fumigatus pulmonary infection in animals. (onacademic.com)

The pilus islet is present in a minority of pneumococcal isolates recovered from human invasive infections and is therefore not an essential virulence factor in these infections. (biomedcentral.com)

Our data provide evidence that secondary respiratory infections do not drive mortality in COVID-19 and clinical management strategies should prioritize reducing viral replication and maximizing host responses to SARS-CoV-2. (cdc.gov)
AECOPD triggered by a bacterial and viral co-infection increases circulating levels of the systemic inflammatory marker, serum amyloid A (SAA). (frontiersin.org)

Taheri Y, Jokovic N, Vitorovic J, Grundmann O, Maroyi A and Calina D: The burden of the serious and difficult-to-treat infections and a new antibiotic available: Cefiderocol. (spandidos-publications.com)

Abs were necessary and sufficient for protection because Ab-deficient muMT mice did not develop postexposure protection, only becoming resistant to lung infection after transfer of immune sera from NP-exposed mice. (umassmed.edu)
We have developed adult and suckling mouse models of these diseases to investigate transmission and immune responses to infection. (viin.org.au)
Current research projects focus on the altered immune homeostasis observed in mice that cannot secrete antibodies as a result of a mutation in the polymeric Ig receptor. (viin.org.au)
These immune responses may be important both in the prevention of invasive diseases and in the reduction of upper respiratory carriage of pathogens. (bmj.com)
The abundance of certain resident macrophages in the urinary tract may indicate the critical role of host cell-microbial interaction in preparing the immune response to infection [ 9 ] [ 10 ] . (encyclopedia.pub)

NP exposure of aged mice failed to protect against subsequent lung infection despite eliciting a robust Ab response. (umassmed.edu)
These findings suggest that NP exposure elicits extended protection against pneumococcal lung infection by generating long-lived CD138(+) ASC and that the protective efficacy of these responses declines with age. (umassmed.edu)
The mHAQ mouse has decreased MPYS protein in B cells, T cells, Ly6C hi monocytes, bone marrow-derived dendritic cells, and lung tissue. (aai.org)
Despite ongoing efforts to reduce AECOPD rates with inhaled corticosteroids, COPD patients remain at heightened risk of developing serious lung infections/AECOPD, frequently leading to hospitalization and infection-dependent delirium. (frontiersin.org)

Pneumococci are positive for " data-footer="Positive bile solubility test"> bile solubility , " data-footer="Positive inulin fermentation"> inulin fermentation , quellung reaction, are " data-footer="Optochin susceptible"> susceptible to optochin and are pathogenic to mouse. (microrao.com)

Disclosed herein are methods of detecting microbial infection in mammalian subjects comprising treatment of a sample and detection of polysaccharide antigenic components. (onacademic.com)

Native human antibody to Shr promote mice survival after intraperitoneal challenge with invasive Group A. Chatterjee N, Huang YS, Lyles KV, Morgan JE, Kauvar LM, Greer SF, Eichenbaum Z. J infect Dis. (gsu.edu)

The frequency of necrotizing fasciitis has been on the rise because of an increase in immunocompromised patients with diabetes mellitus, cancer, alcoholism, vascular insufficiencies, organ transplants, human immunodeficiency virus (HIV) infection, or neutropenia. (medscape.com)

Especially in non-neutropenic patients with life-threatening infections caused by Candida spp. (ifemarketing.com)
08 mcg/mL) and after single oral doses of 50 to 400 mg, fluconazole plasma concentrations and area under the plasma concentration-time curve (AUC) are dose proportional In Germany, fluconazole is approved for therapy of life-threatening infections caused by Candida spp. (ifemarketing.com)

Officially known as 'Group A streptococcal infection' it is transmitted by close contact with an infected individual, either through touch or coughs. (euronews.com)
Here is all the info about group A strep that you need to know. (madeformums.com)
Remember that there are lots of viruses around at the moment so if your child is unwell, it may not be related to group A strep. (madeformums.com)
At the moment, because rates of group A strep are high, doctors have been advised to have a lower-than-normal threshold for giving antibiotics for sore throats. (madeformums.com)
If your child seems very unwell - whether or not you think it is related to group A strep - then seek urgent medical help. (madeformums.com)

We investigated whether bacterial respiratory infections were associated with poor clinical outcome of COVID-19 in a prospective, observational cohort of 589 critically ill adults, all of whom required mechanical ventilation. (cdc.gov)
The second dose simply adds a little more antifungal power to treat a stubborn infection Fluconazole is one of the new antifungal triazoles undergoing clinical trials. (ifemarketing.com)

Based on their thick layer of capsular polysaccharide (CPS), S. pneumoniae have been classified into about 97 different specific types according to the Danish classification system [ 2 , 3 ]. (mdpi.com)
We examined the distribution of the pilus islet, using the presence of the rlrA gene as a marker for the locus, among a collection of invasive isolates recovered in Portugal and analyzed its association with capsular serotypes, clusters defined by the pulsed-field gel electrophoretic profiles (PFGE) and multilocus sequence types. (biomedcentral.com)

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