• The present study shows that, unlike in the laboratory mouse in which spermatozoa of the vas deferens are found mainly in the epididymal region of the duct, spermatozoa in the hopping mouse are localized mainly to the middle and urethral regions of the vas deferens which lies in the inguinal and lower abdominal region of the body cavity. (edu.au)
  • However, in the adult male spinifex hopping mouse, Notomys alexis, similar numbers of spermatozoa are found in the vas deferens to those in the cauda epididymidis. (edu.au)
  • Ultrastructural observations of the cells lining the duct indicate that there are not any marked differences in morphology compared with the cells lining the duct in common laboratory murids, but the infoldings of the vas deferens of the hopping mouse are highly vascular which might facilitate supply of oxygen and nutrients to the spermatozoa residing in the lumen. (edu.au)
  • The American white-footed mouse (Peromyscus leucopus) and the deer mouse (Peromyscus maniculatus), as well as other common species of mouse-like rodents around the world, also sometimes live in houses. (wikipedia.org)
  • Rats and mice are so closely linked to man they are called domestic rodents. (in.gov)
  • Well, okay, there's no official word in the article about the rodents' emotional states, but certainly when stem cells were injected into mice with leg injuries, the muscle grew back. (slashdot.org)
  • The debate over what to do with the invasive mice that blanket South Farallon Islands comes down to a choice between bombarding the rodents with deadly poison or waving the white flag of surrender, a federal study concluded Friday. (sfgate.com)
  • Densities of 500 mice per acre - as many as 60,000 in all - have been counted on the islands during peak season, the highest density of rodents on any island in the world. (sfgate.com)
  • Worst of all, they attract burrowing owls, which feed on the rodents until the mice population crashes in the winter. (sfgate.com)
  • Mice and voles are small rodents that sometimes cause problems in gardens and greenhouses. (rhs.org.uk)
  • Mouse , (genus Mus ), the common name generally but imprecisely applied to rodents found throughout the world with bodies less than about 12 cm (5 inches) long. (britannica.com)
  • mouse, name applied to numerous species of small rodents , often having soft gray or brown fur, long hairless tails, and large ears. (encyclopedia.com)
  • The chief distinction between these animals and the variety of rodents called rats is in size: mice are usually smaller. (encyclopedia.com)
  • Many small rodents are adapted for leaping or hopping and are named accordingly, e.g., the North American kangaroo rat and Asian jumping mouse . (encyclopedia.com)
  • Most, but not all, of the rodents called mice are members of the rodent subclass Myomorpha, or mouselike rodents. (encyclopedia.com)
  • The pocket mouse and the kangaroo rats and mice are members of the suborder Sciuromorpha, or squirrellike rodents. (encyclopedia.com)
  • Keep in mind that key among the lobbyists who denied protection to rodents were those who profit from selling rats and mice for experimentation and testing. (awionline.org)
  • Mice and rats are also relatively inexpensive and can be bought in large quantities from commercial producers that breed rodents specifically for research. (livescience.com)
  • The rodents are also generally mild-tempered and docile, making them easy for researchers to handle, although some types of mice and rats can be more difficult to restrain than others . (livescience.com)
  • Another reason rodents are used as models in medical testing is that their genetic, biological and behavior characteristics closely resemble those of humans, and many symptoms of human conditions can be replicated in mice and rats. (livescience.com)
  • Some rodents, called SCID (severe combined immune deficiency) mice, are naturally born without immune systems and can therefore serve as models for normal and malignant human tissue research , according to the FBR. (livescience.com)
  • ZURICH, SWITZERLAND-Nearly 700 scientists representing 27 countries convened at the University of Zurich Monday to formally announce that their experimentation on mice has been motivated not by a desire to advance human knowledge, but out of sheer distaste for the furry little rodents. (theonion.com)
  • Paris (AFP) - Zapping worn-out cells in the organs of "middle-aged" mice caused the rodents to live longer, healthier lives, said a study Wednesday that raised intriguing prospects for anti-ageing treatments. (yahoo.com)
  • In May 2014, researchers reported that injections of young mouse blood boosted learning and memory in older rodents. (yahoo.com)
  • Mice are commensal rodents who depend on man for food and shelter. (reference.com)
  • It is uncommon for mice and other small rodents to carry rabies, but they can contract the disease in rare situations where they are attacked by another an. (reference.com)
  • In human studies, SHANK2 has been associated with rare cases of autism and these two mice add to the ever-growing list of rodents (according to SFARI.org, 17 rodent models debuted in 2011 alone) that are being created to investigate the functional consequences of genetic mutations linked to autism, in the hopes of understanding mechanisms underlying core symptoms. (nature.com)
  • The Yale team said that up to 19 percent of ticks, and up to 42 percent of mice (and other rodents) that carry the Lyme bacterium also carry B. microti . (medicinenet.com)
  • To milk mice, the research team had to anaesthetize the rodents and use specially adapted pumps fitted to their tiny teats. (nationalgeographic.com)
  • On-orbit operations require the ability to launch and maintain rodents (mice and rats) in a habitat and in some cases also require rodent euthanasia, dissection, and tissue sample preparation and preservation. (nasa.gov)
  • When he gave it to normal mice, the rodents bulked up, just as would happen if the myostatin gene in these animals was turned off. (hopkinsmedicine.org)
  • The mouse grimace scale (MGS) was able to detect pain in experiments typically used by scientists. (scientificamerican.com)
  • The mice will live in microgravity during their mission, allowing scientists to learn more about muscle development and muscle atrophy. (novartis.com)
  • Scientists say they "serendipitously" discovered that the drug that quickly reversed Alzheimer's disease in mice. (cnn.com)
  • Scientists say they "serendipitously" discovered that a drug used to treat a type of cancer quickly reversed Alzheimer's disease in mice. (cnn.com)
  • An unlikely, decadelong journey that began with the discovery of a rapidly aging mouse has led scientists to a protein that seems to protect animals from cancer and other scourges of old age-with no apparent downsides. (wired.com)
  • In a related study] scientists used a dose on mice equivalent to just 35 bottles a day. (newyorker.com)
  • Then the scientists placed the mice back into the box, shining a light onto the animals' brains to force the modified neurons to fire. (scientificamerican.com)
  • Scientists can now breed genetically-altered mice called "transgenic mice" that carry genes that are similar to those that cause human diseases. (livescience.com)
  • According to a 500-word statement, scientists hate mice for 'their beady little eyes,' 'their repulsive tails,' and 'the annoying little squeaking sounds they make. (theonion.com)
  • According to Gresham, scientists have enjoyed dissolving mice in acid, spinning them in centrifuges, blowing them up in vacuum chambers, and forcing them to navigate exit-free mazes for years-all the while towering above them, laughing. (theonion.com)
  • After applauding the scientists for coming forward, anthropologist Brent Wrigley suggested that the hatred of mice may be the single most important factor in the evolution of modern science. (theonion.com)
  • Mouse-killing isn't solely the province of organic and medical scientists. (theonion.com)
  • Many other scientists kill mice, as well. (theonion.com)
  • Scientists at the Massachusetts Institute of Technology have developed the ability to implant mice with false memories. (csmonitor.com)
  • They first put mice in a chamber -- the scientists called it the Red Room -- and let the animals roam around exploring so they could build up a contextual memory of it. (csmonitor.com)
  • Then the scientists put the mice in a second chamber and sent a light into the brain, which would have triggered memories of the first chamber. (csmonitor.com)
  • The scientists had planted a false memory, and the mice believed it. (csmonitor.com)
  • sterlingda writes to tell us that scientists have built a mouse-levitating superconducting magnet , working on behalf of NASA to study variable levels of gravity. (slashdot.org)
  • Scientists have genetically engineered mice to produce human proteins in their semen, which may allow drugs to be farmed from genetically-modified (GM) livestock. (bbc.co.uk)
  • To create the diagram, scientists combined data from more than 1000 mouse brains, each of which was divided into 140 slices. (news.com.au)
  • Ren said scientists had assumed that significant conservation would occur at the deeper level of gene regulation as well, that similar genes in humans and mice would be expressed in similar ways. (ucsd.edu)
  • Scientists who watched tumor cells spread in living mice said on Sunday they had found a gene signal controlling how cancer cells move, which could help companies design new drugs to fight the disease. (ibtimes.com)
  • Scientists working for Cancer Research UK used hi-tech imaging techniques to watch how breast cancer cells spread in mice. (ibtimes.com)
  • In a study performed in an industrial Canadian city, scientists raised mice in a shed downwind of a highway and two steel mills. (ewg.org)
  • An experimental farm in Russia could soon be producing human breast milk substitutes following successful milking trials on mice, scientists report. (nationalgeographic.com)
  • Scientists have identified a "fear" gene in mice that when removed turns them into daredevils, seemingly heedless to both inborn fears and risky situations that normal mice have learned to avoid through experience. (latimes.com)
  • Canadian scientists were able to reverse diabetes in mice with a human stem cell transplant, igniting hopes for a cure for the widespread disease -- caused by the failure of the pancreas to produce enough insulin to stabilize blood sugar levels -- in humans. (ibtimes.com)
  • For that, he says, scientists use a T-shaped platform several feet off the ground, in which one arm was protected by walls to give the mice a sense of safety, and the other arm is an exposed plank with nowhere to hide. (npr.org)
  • He says the genetically engineered mice also may help scientists figure out why some people are prone to excessive anxiety or aggression: Because mice and humans are remarkably similar when it comes to brain transmitters like serotonin, it's likely that some of the same genes are responsible for regulating the brain transmitters in both species. (npr.org)
  • However, says Davis, scientists need to be cautious when using animal models created through genetic engineering: "It's conceivable that by knocking out specific genes, you're going to create mice that may have interesting properties, but will never be duplicated in nature. (npr.org)
  • Nature Communications Sometimes scientists use bald mice for tissue grafts, and sometimes scientists use them just because they're bald. (motherjones.com)
  • Scientists from the Johns Hopkins University School of Medicine have discovered that repurposing a drug used for pre-leukemia was able to erase brain tumor cells in mice. (healthcentral.com)
  • Male mice from four segmental trisomic strains covering the D21S17-ETS2 (syntenic to MMU16) were examined with an exhaustive battery of cognitive tests, motor tasks and MRI and compared with TS65Dn that encompasses D21S17-ETS2. (springer.com)
  • Newborn male mice are distinguished from newborn females by noting the greater anogenital distance and larger genital papilla in the male. (wikipedia.org)
  • Manzanedo, C., Aguilar, M. A., Rodriguez-Arias, M. & Minarro, J. Effects of dopamine antagonists with different receptor blockade profiles on morphine-induced place preference in male mice. (nature.com)
  • To test this, Uraki and his colleagues infected male mice with Zika and monitored the virus' presence in different cell types. (upi.com)
  • Male mice call to females in ultrasonic frequencies that when slowed down resemble songs. (amnh.org)
  • Adult male mice produce complex calls around females, or when they detect female pheromones, as a 2005 study published in the journal PLoS ONE , analyzed. (amnh.org)
  • Male mice create complex patterns with their squeaks during reproduction. (reference.com)
  • Previous studies have described how male mice actively pursue and mount mates, while females "just sit there and let things happen," says Catherine Dulac at Harvard University in Cambridge, Massachusetts, US. (newscientist.com)
  • In 2002, Dulac and her colleagues described how male mice genetically engineered to lack TRPC2 mate indiscriminately with the male and female cage-mates. (newscientist.com)
  • Dulac interprets this result to mean that the female mouse brain is not necessarily hard-wired differently from that of male mice, at least when it comes to mating behaviours. (newscientist.com)
  • While normal male mice generally show curiosity before trying to chase an intruder out of their territory, Deneris says the knockout mice "would attack the intruder much more quickly and much more vigorously … In many cases they would just see the intruder in the cage and go after it. (npr.org)
  • The neurons, identified in mice, are activated when an animal is hungry, effectively dampening pain associated with chronic inflammation, so that the animal can answer to competing physiological cues to find or take in nourishment. (genengnews.com)
  • What the neurons don't do is diminish how the mice feel acute pain, which means that hungry animals can still respond to dangerous stimuli, such treading on something sharp. (genengnews.com)
  • AgRP neuron inhibition in hungry mice reduces food intake, while activation of AgRP neurons in sated mice robustly increases food intake," the team explains. (genengnews.com)
  • Their studies in mice showed that stimulating the AgRP neurons was enough to reduce chronic pain, but not acute pain responses. (genengnews.com)
  • Conversely, inhibiting AgRP neurons in food-deprived mice significantly reduced the usually protective effect of hunger on inflammatory pain. (genengnews.com)
  • The brains of all the mice were examined to look for a particular type of stem cell that can develop into neurons and other nervous system cells within the brain - neural progenitor cells (NPC). (www.nhs.uk)
  • These findings suggest that SUDEP is caused by apparent parasympathetic hyperactivity immediately following tonic-clonic seizures in DS mice, which leads to lethal bradycardia and electrical dysfunction of the ventricle. (nih.gov)
  • The report is based on the findings from a study in mice which has shed further light on the biological processes involved in the changes to the lungs caused by the cystic fibrosis mutation. (www.nhs.uk)
  • In summary, our findings suggest that gut bacteria promote endometriosis disease progression in mice. (medscape.com)
  • The findings, published in the journal Cancer Research, show regular consumption of dietary emulsifiers in mice exacerbated tumor development. (prweb.com)
  • A major consequence of these findings is that mice (and their rat and hamster relatives) are likely to be particularly poor models in which to study the effects of DMD on the brain. (redorbit.com)
  • The findings, part of a series of related papers being published together in Nature , Science , and Genome Research , derive from the ongoing mouse ENCODE (Encyclopedia of DNA Elements) project, a multi-institution effort launched in 2007 to build a comprehensive parts list of functional elements of the mouse genome. (ucsd.edu)
  • To investigate the contribution of this mutation and the consequential lack of response to INK4 inhibitors to tumor development, we have generated knock-in mice carrying a Cdk4 R24C allele ( 17 ). (pnas.org)
  • This simulation shows the spread of a favorable mutation through a population of pocket mice. (hhmi.org)
  • Tumor cells from human patients who were likely to have the IDH1 mutation were injected into the skin of mice. (healthcentral.com)
  • Despite their similarity to members of the genus Mus , genetic evidence suggests that the African spiny mice may be more closely related to gerbils than to common mice. (wikipedia.org)
  • Last year, they reported that removing old cells-that is, cells with a genetic marker indicating senescence-from these mice could help them stay healthier longer. (wired.com)
  • Both the original human and mouse genome projects gave us the sequence of genetic letters (adenine, thymine, guanine and cytosine) that comprise each organism, but no idea how they worked or worked together to create and sustain life," said Ren. (ucsd.edu)
  • The mouse is not our closest genetic cousin, of course. (ucsd.edu)
  • Genetic Loci associated with susceptibility to IDDM have been identified in the NOD mouse strain through the development of congenic mouse strains, which have identified several insulin dependent diabetes (Idd) loci. (wikipedia.org)
  • Genetic and pathogenic basis of autoimmune diabetes in NOD mice. (wikipedia.org)
  • To analyse facial expressions in mice, geneticist Jeffrey Mogil at McGill University in Montreal, Canada, and his colleagues have adapted a coding system used to measure pain in infants. (scientificamerican.com)
  • van Deursen, Baker, and their colleagues wanted to see whether these mice would develop cancer. (wired.com)
  • For their study, she and her colleagues carried out experiments in cell culture and mice engineered to produce large amounts of the human beta-amyloid early in life. (medicalnewstoday.com)
  • Mallucci and colleagues treated mice that were bred to develop a form of prion disease similar to mad cow disease and Creutzfeldt-Jakob disease. (newscientist.com)
  • Dr. Aileen Anderson of the University of California, Irvine and colleagues tested 37 mice, damaging their spinal cords surgically and then transfusing either the StemCells product, ordinary human skin cells or a placebo. (reuters.com)
  • The mice created by Francois Pothier and colleagues at Laval University, Canada, secrete human growth hormone (hGH) in their ejaculate. (bbc.co.uk)
  • But in a mouse model of the syndrome, symptoms could be reversed completely, even in animals that were severely affected, Dr. Bird and colleagues reported online in the Feb. 9 issue of Science . (medpagetoday.com)
  • Similar in appearance to mice of the genus Mus , spiny mice are small mammals with bare, scaled tails . (wikipedia.org)
  • Though African spiny mice originated in the deserts of Africa, they are frequently kept as exotic pets in other parts of the world, particularly Western nations such as the United States . (wikipedia.org)
  • In the pet trade, they are most commonly referred to as Egyptian spiny mice or, more simply, spiny mice. (wikipedia.org)
  • Due to their desert origin, spiny mice thrive at hot temperatures and should be maintained around 27 °C (81 °F). These animals are very social and should always be housed in groups when possible. (wikipedia.org)
  • As spiny mice are prone to obesity, it is important to provide ample space and environmental enrichment to encourage exercise. (wikipedia.org)
  • Lifespan for spiny mice is 4 to 7 years. (wikipedia.org)
  • Captive housing of spiny mice in the mid-1960s uncovered their sensitivity to developing diabetes . (wikipedia.org)
  • That is, spiny mice were kept as pets and maintained on bird food consisting of fat-rich pumpkin, sesame, and sunflower seeds. (wikipedia.org)
  • Further studies, in the Institute of Biochemistry in Geneva, revealed that spiny mice manifest low insulin secretion capacity, low response to glucose, and faint first-phase insulin release, despite pancreatic iselt hypertrophy and hyperplasia. (wikipedia.org)
  • To date, spiny mice are the only mammals known to do so. (wikipedia.org)
  • Within the genus there are four distinctive groups: spiny mice (subgenus Pyromys ), shrew-mice (subgenus Coelomys ), rice field mice and the house mouse (subgenus Mus ), and African mice (subgenus Nannomys ). (britannica.com)
  • Similar studies in conditional KO mice demonstrated that brain, but not cardiac, KO of Scn1a produced cardiac and SUDEP phenotypes similar to those found in DS mice. (nih.gov)
  • Systematic broad-based phenotyping is performed by each IMPC center using standardized procedures found within the International Mouse Phenotyping Resource of Standardised Screens (IMPReSS) resource. (mousephenotype.org)
  • Mice can now be found all across North America, in every state including coastal Alaska, and in all but northernmost Canada. (in.gov)
  • We found that dopamine-deficient mice are unable to mount a normal locomotor response to morphine, but a small dopamine-independent increase in locomotion remains. (nature.com)
  • We found that microbial diversity was altered in faeces from mice with endometriotic lesions and that mice with endometriosis had a higher abundance of Bacteroidetes and lower abundance of Firmicutes in their guts than mice without endometriosis. (medscape.com)
  • For example, they found that when they exposed normal mice to a chemical that causes lung and skin tumors, all of them got cancer. (wired.com)
  • They also found that these animals developed fatal cancers much later than normal mice-after about 2 years, only 15% of the engineered mice had died of cancer, compared with roughly 40% of normal mice. (wired.com)
  • We found that when the aneuploidy level became low'-just like in van Deursen's healthy mice-'you had more tumorigenesis,' not less, says Cristina Montagna, a molecular geneticist at Albert Einstein College of Medicine in the Bronx, New York. (wired.com)
  • Two synthetic antioxidants that may prove to be more powerful versions of those found in nature reversed age-related memory loss in mice, a University of Southern California study found. (eurekalert.org)
  • It found that the only sure-fire way to get rid of the house mice without further jeopardizing the island ecosystem is to shower the craggy hunk of rock with poisoned pellets from a helicopter. (sfgate.com)
  • In previous research, he found an association between defects in MSC and age-related osteoporosis in mice. (medicalnewstoday.com)
  • Dr Rutkowski has found that an unhealthy microbiome promotes the spread of hormone receptor-positive breast cancer in mouse models. (forbes.com)
  • But a team using StemCells Inc's nerve stem cells taken from aborted fetuses found that even a month after injury, the cells took up residence in the spine, proliferated and helped mice walk better. (reuters.com)
  • I found a rather nice copper mouse - not quite brass - but I actually find myself wanting one. (halfbakery.com)
  • We found that Zika virus infection is able to replicate in the testes, and in doing so causes inflammation and decreases testosterone levels in infected mice," Uraki said. (upi.com)
  • Health inspectors found three "critical" violations, including "evidence of mice or live mice present in facility's food and/or non-food areas," according to Health Department records. (nypost.com)
  • It was also ordered closed in 2011, when inspectors found mouse droppings "throughout the kitchen" and slapped owners with a whopping 67 violation points, according to Brooklyn Daily . (nypost.com)
  • Mice are found all over the world. (reference.com)
  • To their surprise, they found that while much conservation did exist, the expression profiles of some distinct biological pathways in mouse samples diverged considerably from human samples. (ucsd.edu)
  • That's basically what we did-try different collisions until we found one which would turn a couple of ordinary spiral galaxies into something like The Mice. (hawaii.edu)
  • The Johns Hopkins scientist who first showed that the absence of the protein myostatin leads to oversized muscles in mice and men has now found a second protein, follistatin, whose overproduction in mice lacking myostatin doubles the muscle-building effect. (hopkinsmedicine.org)
  • Identification of trans Protein QTL for Secreted Airway Mucins in Mice and a Causal Role for Bpifb1. (nih.gov)
  • Heart tissue in mice is one of several types that benefit from more BubR1 protein. (wired.com)
  • van Deursen, along with a then-graduate student, Darren Baker, engineered mice to produce less BubR1, a protein that helps cells segregate their chromosomes when they divide. (wired.com)
  • Delivering a light-sensitive protein (highlighted in green) to specific cells in the retina (highlighted in red) of a blind mouse makes those cells sensitive to light, restoring some vision. (technologyreview.com)
  • By rebooting protein production, the treatment halted any further degeneration in the mice. (newscientist.com)
  • Post mortems showed that brain connections lost in the untreated mice remained healthy, and completely normal protein production had resumed in the treated animals, even though the prions continued to accumulate. (newscientist.com)
  • Using these mice combined with a novel viral strategy, memory engram cells (green) for a contextual fear memory were labeled with a light-sensitive protein ChR2. (scientificamerican.com)
  • Mouse milk is very protein-rich, and this can also translate into very high concentrations of transgenic protein," Patrick van Berkel, a senior director at the Danish biotech company Genmab, wrote in an email. (nationalgeographic.com)
  • House mice, particularly albino strains, are extensively used in biological and medical experimentation and are also sometimes kept as pets. (encyclopedia.com)
  • I don't think anyone thinks it's normal but from what my "experimentation" (mouse traps in the attic) seems to indicate, they certainly do like it. (slashdot.org)
  • Here, we showed that antibiotic treatment reduced endometriotic lesions in a mouse model of endometriosis. (medscape.com)
  • 2017). We showed that mice treated with VNMA or metronidazole alone had fewer macrophages in their lesions and lower peritoneal IL-1β concentration than vehicle-treated mice. (medscape.com)
  • Belichenko NP, Belichenko PV, Kleschevnikov AM, Salehi A, Reeves RH, Mobley WC (2009) The "Down syndrome critical region" is sufficient in the mouse model to confer behavioral, neurophysiological, and synaptic phenotypes characteristic of Down syndrome. (springer.com)
  • Primarily nocturnal animals, mice compensate for their poor eyesight with a keen sense of hearing, and rely especially on their sense of smell to locate food and avoid predators. (wikipedia.org)
  • Mice in their natural habitats are primarily nocturnal, although some will occasionally forage during the day. (britannica.com)
  • The widely distributed long-tailed field mouse, Apodemus sylvaticus, is a nocturnal, burrowing creature that prefers succulent plant food and frequently invades gardens and houses. (encyclopedia.com)
  • The house mouse is primarily a nocturnal animal. (tolweb.org)
  • The research involves a combination of tissue culture to understand cell-cell communication and genetically-modified mice to mimic human disease and to test potential new medicines. (cam.ac.uk)
  • In electrophysiological tests on hippocampal tissue of healthy and Angelman mice, the compound made obtaining LTP significantly easier, although observing LTP in Angelman mice is still more difficult than in normal mice, Marshall said. (redorbit.com)
  • When we disrupted the microbiome equilibrium in mice by chronically treating them antibiotics, it resulted in inflammation systemically and within the mammary tissue,' said Melanie Rutkowski, PhD from the University of Virginia's Department of Microbiology, Immunology and Cancer Biology and lead author of the paper. (forbes.com)
  • For years, I've used lab mice to research cell breakdown in living tissue-and I've been lucky enough to make some pretty important medical advancements along the way,' said researcher Ellen Gresham of the Harvard Institute for Advanced Studies. (theonion.com)
  • The truth is, mice are particularly ill-suited for our tissue study,' Gresham added. (theonion.com)
  • The Center for the Advancement of Science in Space (CASIS) obtains tissue samples from mice flown to the International Space Station to support valuable commercial muscle wasting research. (nasa.gov)
  • denotes BALF sample from a C57BL/6J mouse treated with allergen in a separate experiment and used as positive control for antibody reactivity. (nih.gov)
  • The CASIS mice include 16 week-old C57Bl female mice, 5 wild type and 5 transgenic MuRF-1 knockout. (nasa.gov)
  • Prior research had also shown that the elimination of senescent cells in ageing mice extended their healthy lifespan. (voanews.com)
  • Mice minus these aged or "senescent" cells went on to enjoy better kidney function and stronger hearts, a later onset of cancer and fewer cataracts than untreated peers, according to a research paper in the journal Nature. (yahoo.com)
  • The mice that were treated to remove their senescent cells had a lifespan extension. (yahoo.com)
  • We knew that senescent cells were accumulating with age in natural tissues and the thought was: let's just start removing these things starting at mid-age in mice and see what the consequences were," Baker said. (yahoo.com)
  • A future step in research would be to test the method on already aged mice, to see if removing senescent cells can reverse age-related decline. (yahoo.com)
  • Behavioral assessment of the mice: P-L Roubertoux, A. Ghata, C. Bartoli, M. Carlier. (springer.com)
  • But strikingly, when these immune-deficient mice were put in the same cage as healthy mice, the healthy mice started to come down with symptoms of liver disease, and also got fatter. (huffingtonpost.com)
  • And it's these bad bacteria that were transmitted from mouse to mouse, causing the healthy mice to also experience changes in their gut microbes -- and making them fat. (huffingtonpost.com)
  • We have Ehrlich come to our house every other month to spray for insects and prevent mice. (terrificpets.com)
  • The teeming hordes of mice are devouring the islands' insects and spiders, the same food that the endemic Farallon arboreal salamander needs to survive. (sfgate.com)
  • At the end of the day, your interest in this mouse will likely hinge on your appreciation of insects. (tomshardware.com)
  • In some places, certain kinds of field mice are locally common. (wikipedia.org)
  • Field mice sometimes bite off strawberry and other fruits before they are ripe and leave the berries in small heaps among the plants. (rhs.org.uk)
  • In cold weather field mice often enter greenhouses and cold frames, where they can destroy many seedlings overnight. (rhs.org.uk)
  • Claiming that it would be too expensive, research industry lobbyists succeeded in obtaining a 2002 amendment to the Animal Welfare Act specifically excluding rats (of the genus Rattus ), mice (of the genus Mus ), and birds bred for research from the protections afforded. (awionline.org)
  • We started Ghost Mice in 2002 because we were tired of being restricted. (wikipedia.org)
  • It is believed the Eurasian house mice disembarked from seal-hunting ships visiting the 120-acre South Farallon Islands in the 19th century and multiplied at a feverish pace over the last century. (sfgate.com)
  • Young house mice stay with their mother until they are about 21 days old . (tolweb.org)
  • Wild house mice live approximately 12 to 18 months, and captive house mice have an average life span of 2 years. (tolweb.org)
  • Breeding of captive house mice occurs any time during the year, for wild house mice, breeding during the colder months of the year seems to be restricted. (tolweb.org)
  • Another source of communication that house mice rely on is through the use of pheremones . (tolweb.org)
  • House mice try to avoid being eaten by keeping away from the open and by being fast . (tolweb.org)
  • Do house mice hibernate? (reference.com)
  • House mice gain entry to structures by climbing, crawling and chewing, and they construct runways and build nests under floorboards and throughout walls. (reference.com)
  • While they have poor eyesight, mice have good peripheral vision that allows them to detect movement. (in.gov)
  • Mice, in certain contexts, can be considered vermin which are a major source of crop damage, causing structural damage and spreading diseases through their parasites and feces. (wikipedia.org)
  • I do have 2 cats but because of all the diseases mice carry I would preferr to have them gone before we move in. (terrificpets.com)
  • Alterations in gut microbes may increase the susceptibility to obesity and fatty liver disease and also make it possible to spread these diseases, at least in mice. (huffingtonpost.com)
  • DNA in the sperm of the mice in the polluted area contained 60% more mutations, had more strand breaks, and had more bases that had been chemically modified via the addition of a methyl group. (ewg.org)
  • Mice differ from voles in having tails that are longer than their bodies. (rhs.org.uk)
  • Astronomers Alar and Juri Toomre used The Mice to illustrate this idea, showing how the long tails noted by Vorontsov-Vel'Yaminov could be drawn out of ordinary spiral galaxies by gravitational forces. (hawaii.edu)
  • And small clumps of stars and gas within the tails of The Mice, which are also seen in computer simulations, may eventually drift away to become small free-floating galaxies. (hawaii.edu)
  • As time passed however-21 days in photo A, 10 months in photo B-these mice showed a voracious appetite, eating and eating until they ballooned into small fur pillows with tails. (motherjones.com)
  • We've heard obesity can be 'spread' between friends when we copy each other's eating habits, but a new study in mice suggests obesity could actually be infectious. (huffingtonpost.com)
  • injected ISRIB into mice, the animals showed improved memory: for example, they learnt to locate a hidden platform in a water maze more rapidly than controls. (elifesciences.org)
  • Over eight out of ten animals used in research at Cambridge are mice. (cam.ac.uk)
  • Though these animals are similar to pet mice and rats, the tail of a spiny mouse is much more delicate. (wikipedia.org)
  • To their surprise, instead of tumor-filled mice, they wound up with animals that aged very quickly. (wired.com)
  • And the mice looked veritably Olympian on a treadmill, running about twice as far-200 meters rather than 100 meters-as control animals. (wired.com)
  • Using the mouse as a model, the team first observed how animals that hadn't eaten for 24 hours responded to either acute pain or longer-term inflammatory pain. (genengnews.com)
  • However, the term "animals," for purposes of the protections delineated in the statute, is defined so as to expressly exclude rats, mice and birds-the very animals who constitute roughly 95% of animals in research! (awionline.org)
  • As it stand now, the rats, mice and birds who constitute the vast majority of the animals in research have no legal protection. (awionline.org)
  • This caused the mice to recall the memory of being shocked, and the animals froze-suggesting that the memory had been encoded in the first place. (scientificamerican.com)
  • In fact, 95 percent of all lab animals are mice and rats, according to the Foundation for Biomedical Research (FBR). (livescience.com)
  • However, research that works in mice and other animals often fails in a human trial. (medicinenet.com)
  • But that doesn't mean the mice themselves are about to become biotech dairy animals, Sadchikova cautioned. (nationalgeographic.com)
  • The Transporter and Access Unit are de-stowed and animals are transferred from the Transporter to two Habitats using Mouse Transfer Boxes. (nasa.gov)
  • In the study, mice engineered to have a particular immune deficiency developed fatty liver disease and got fatter when fed a Western-style diet. (huffingtonpost.com)
  • Because the mice had their immune systems disturbed, the bacteria in their guts got 'out of wack,' said study researcher Richard Flavell, a professor of immunobiology at Yale School of Medicine. (huffingtonpost.com)
  • We normally live in symbiosis with the bacteria in our guts , but in the study, the number of 'bad,' disease-associated bacteria increased 1,000-fold in mice with immune problems, Flavell said. (huffingtonpost.com)
  • Viral infection during pregnancy is correlated with increased frequency of neurodevelopmental disorders, and this is studied in mice prenatally subjected to maternal immune activation (MIA). (nature.com)
  • Delovitch TL, Singh B. The nonobese diabetic mouse as a model of autoimmune diabetes: immune dysregulation gets the NOD. (wikipedia.org)
  • Mice that didn't receive CRISPRa injections couldn't stop eating," said study author Navneet Matharu, a researcher in Ahituv's UCSF lab. (medicinenet.com)
  • an alcohol-drinking group that was given the drug by injection during 14 days of abstinence, an alcohol-drinking group that was given an inert injection of salt water, and two similar groups of 12 non-drinking mice that was either given the antidepressant or inert injections. (www.nhs.uk)
  • Over six weeks, different mice were exposed to different once-weekly antibody injections, while others were given dummy injections. (upi.com)
  • As a result research on mice has helped the understanding of both human physiology and the causes of disease. (cam.ac.uk)
  • Many Care2 readers might not like to hear about this research conducted using mice. (care2.com)
  • The work published today in Cancer Research used mouse models of hormone receptor positive (HR+) breast cancer, the most common type in people, representing two-thirds of all cases. (forbes.com)
  • The US is the only country in the world that does not include within its animal welfare laws and regulations the rats, mice and birds who are subjected to research and testing. (awionline.org)
  • This all-too-commonly heard refrain-that it would be much too costly to regulate the huge numbers of mice and rats in research-does not bear up to scrutiny. (awionline.org)
  • Why, for example, does a reproductive physiology study "require" hundreds of mice as research subjects but less than a dozen subjects when done with macaques? (awionline.org)
  • As a physicist, I don't really have much cause to use mice in my regular research, which mostly requires the use of theoretical math,' said Dr. Thomas Huber, author of the 1996 study Mouse Elasticity And Kinetic Rebound In High-Acceleration Collisions . (theonion.com)