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  • strains
  • In addition, some recently developed laboratory mouse strains are derived wholly from other Mus species or other subspecies, such as M. spretus ). (jax.org)
  • Care should be taken that mouse and rat strains do not overlap in strain designations. (jax.org)
  • The goal of the International Mouse Phenotyping Consortium (IMPC) is to discover functional insight for every gene by generating and systematically phenotyping 20,000 knockout mouse strains. (mousephenotype.org)
  • The production of mouse strains from these ES cells are tracked within the 'international Micro-injection tracking system' (iMits) and are made available to the research community via public repositories. (mousephenotype.org)
  • Male mice from four segmental trisomic strains covering the D21S17-ETS2 (syntenic to MMU16) were examined with an exhaustive battery of cognitive tests, motor tasks and MRI and compared with TS65Dn that encompasses D21S17-ETS2. (springer.com)
  • We wish to express our gratitude to the European Mouse Mutant Archive (EMMA) for the generous gift of two strains of segmental trisomic mice. (springer.com)
  • There are several thousand different strains of knockout mice. (wikipedia.org)
  • rodent
  • A mouse (plural: mice) is a small rodent characteristically having a pointed snout, small rounded ears, a body-length scaly tail and a high breeding rate. (wikipedia.org)
  • The white-footed mouse ( Peromyscus leucopus ) is a rodent native to North America from Ontario , Quebec , Labrador , and the Maritime Provinces (excluding the island of Newfoundland ) to the southwest United States and Mexico. (wikipedia.org)
  • researchers
  • When the researchers modeled the effects in mice, they found it strengthened the connections between neurons that make learning possible - what is known as synaptic plasticity - by increasing the action of a cell receptor critical to forming memories. (ucsf.edu)
  • The researchers chose to analyze endothelial cells derived from mouse liver, because the liver can be induced to sprout new blood vessels when regenerating itself following partial surgical removal. (nih.gov)
  • To determine if the mouse findings were relevant to human cancers, the researchers then examined CD276 expression patterns in endothelial cells derived from cancer patients. (nih.gov)
  • Researchers at the Eaton-Peabody Laboratory have successfully isolated adult stem cells from the tissue of the mouse utricle. (tinnitusformula.com)
  • Our researchers have used mice to model aneuploidy, where some cells in the embryo contain an abnormal number of chromosomes. (cam.ac.uk)
  • Our researchers developed a mouse model of aneuploidy by mixing 8-cell stage mouse embryos in which the cells were normal with embryos in which the cells were abnormal and showed that the embryo has an amazing ability to correct itself. (cam.ac.uk)
  • By causing a specific gene to be inactive in the mouse, and observing any differences from normal behaviour or physiology, researchers can infer its probable function. (wikipedia.org)
  • Peromyscus
  • Anderson JF, Johnson RC, Magnarelli LA (1987) Seasonal prevalence of Borrelia burgdorferi in natural populations of white-footed mice, Peromyscus leucopus . (wikipedia.org)
  • 2004) Borrelia burgdorferi infection in a natural population of Peromyscus leucopus mice: a longitudinal study in an area where Lyme borreliosis is highly endemic . (wikipedia.org)
  • Martin LB, Weil ZM, Kuhlman JR & Nelson RJ (2006) Trade-offs within the immune systems of female white-footed mice, Peromyscus leucopus . (wikipedia.org)
  • Martin LB, Weil ZM & Nelson RJ (2007) Immune defense and reproductive pace of life in Peromyscus mice . (wikipedia.org)
  • Ostfeld RS, Miller MC & Hazler KR (1996) Causes and consequences of tick (Ixodes scapularis) burdens on white-footed mice (Peromyscus leucopus) . (wikipedia.org)
  • homologs
  • Because of the small number of patients with partial trisomy 21, we addressed the question in the Mouse in which three chromosomal regions located on MMU10, MMU17 and MMU16 carries almost all the HSA21 homologs. (springer.com)
  • mammal
  • With the exception of the Aye-Aye , the meadow jumping mouse is the only mammal to have eighteen teeth with a dental formula of: 1/1, 0/0, 1/0, and 3/3. (wikipedia.org)
  • genetic
  • Anita Rogic, Nathalie Tessier, Pierre Legendre, François-Joseph Lapointe, Virginie Millien (2013) Genetic structure of the white-footed mouse in the context of the emergence of Lyme disease in southern Québec . (wikipedia.org)
  • Laboratory
  • A key feature of mouse and rat nomenclature is the Laboratory Registration Code or Laboratory code, which is a code of usually three to four letters (first letter uppercase, followed by all lowercase) that identifies a particular institute, laboratory, or investigator that produced, and may hold stocks of, a mouse or rat strain. (jax.org)
  • chromosomal
  • However, some mice survive due to chromosomal rearrangement of proliferating hepatocytes resulting in loss of significant functional components of the transgene. (nih.gov)
  • Adult
  • Adult female B6C3F1 mice were injected sc for 14 days with DEET at 0, 7.7, 15.5, 31, or 62 mg/kg/day. (nih.gov)
  • The adult mouse has a small slender body weighing from ½-ounce to an ounce. (in.gov)
  • specific strain
  • It's a study in which a specific strain of mice, developed at the Novartis Institutes for BioMedical Research (NIBR), will be sent to the International Space Station (ISS) on September 20. (novartis.com)
  • North America
  • Native to central Asia, the mouse arrived in North America with the first European colonists. (in.gov)
  • Mice can now be found all across North America, in every state including coastal Alaska, and in all but northernmost Canada. (in.gov)
  • In North America, breathing dust that has come in contact with mouse excrement has been linked to hantavirus, which may lead to hantavirus pulmonary syndrome (HPS). (wikipedia.org)
  • diseases
  • Mice, in certain contexts, can be considered vermin which are a major source of crop damage, causing structural damage and spreading diseases through their parasites and feces. (wikipedia.org)
  • I do have 2 cats but because of all the diseases mice carry I would preferr to have them gone before we move in. (terrificpets.com)
  • occurs
  • The first written reference to mice kept as pets occurs in the Erya, the oldest extant Chinese dictionary, from a mention in an 1100 BC version. (wikipedia.org)
  • found
  • Systematic broad-based phenotyping is performed by each IMPC center using standardized procedures found within the International Mouse Phenotyping Resource of Standardised Screens (IMPReSS) resource. (mousephenotype.org)
  • I found a rather nice copper mouse - not quite brass - but I actually find myself wanting one. (halfbakery.com)
  • tend
  • Female mice housed together tend to go into anestrus and do not cycle. (wikipedia.org)
  • As a general rule, inbred mice tend to have longer gestation periods and smaller litters than outbred and hybrid mice. (wikipedia.org)
  • Female mice are popular with many owners since they tend to co-habitate with other mice better than males. (wikipedia.org)
  • context
  • Knockout mice also offer a biological and scientific context in which drugs and other therapies can be developed and tested. (wikipedia.org)
  • liver
  • In these mice, the liver parenchyma is replaced by the transgene deficient hepatocytes within about 8 weeks. (nih.gov)
  • inexpensive
  • Reasons for common selection of mice are small size, inexpensive, widely varied diet, easily maintained, and can reproduce quickly. (wikipedia.org)
  • Fancy mice are inexpensive compared with other larger pets, but they are also comparatively short-lived. (wikipedia.org)
  • female
  • Additionally, the urine of female fancy mice does not contain as strong an odor as that of the male mice. (wikipedia.org)
  • As a whole the female jumping mouse is slightly larger, and heavier than the male, but their weight varies quite a bit depending on the season. (wikipedia.org)
  • tail
  • They can vary greatly in size, from small pet mice that are approximately 15-17.5 cm (6-7 in) long from nose to the tip of the tail, to show mice that measure 30 cm (12 in) nose to tail. (wikipedia.org)
  • A mouse with absence of whiskers, blind in one or both eyes, carrying external parasites, having a tumor, sore or legs with fur missing, suffering from any obvious disease or deformity or kinked tail shall be disqualified. (wikipedia.org)
  • The meadow jumping mouse can range in length, from 180 mm to 240 mm, with its tail taking credit for most of its length, usually about 108 mm to 165 mm. (wikipedia.org)
  • similar
  • Note: a few historical examples exist of similar mouse and rat strain designations and these are allowed to stand, with their substrain designations identifying them as unique). (jax.org)
  • As soon as I saw Chris's post I knew I had to blog about it, because I had similar symptoms to these mice . (perfecthealthdiet.com)
  • citation needed] There are several clubs all over the world who host shows for mice, similar to rat shows. (wikipedia.org)
  • The mouse should be perfectly tractable and free from any vice and not subject to fits or other similar ailments. (wikipedia.org)
  • 2001
  • Writer Mike Curtis and penciler Charles Ettinger revamped the character in Shanda Fantasy Arts' SFA's Atomic Mouse, which ran for three issues published from 2001 to 2004. (wikipedia.org)
  • SFA's Atomic Mouse #1 (Sept. 2001) at the Grand Comics Database. (wikipedia.org)
  • 2001) Effects of acorn production and mouse abundance on abundance and Borrelia burgdorferi infection prevalence of nymphal Ixodes scapularis ticks . (wikipedia.org)
  • mammalian
  • Nevertheless, because of its remarkable adaptability to almost any environment, the mouse is one of the most successful mammalian genera living on Earth today. (wikipedia.org)
  • characteristic
  • Belichenko NP, Belichenko PV, Kleschevnikov AM, Salehi A, Reeves RH, Mobley WC (2009) The "Down syndrome critical region" is sufficient in the mouse model to confer behavioral, neurophysiological, and synaptic phenotypes characteristic of Down syndrome. (springer.com)
  • The most interesting characteristic of the meadow jumping mouse is its saltatorial powers. (wikipedia.org)
  • Male
  • If exposed to a male mouse or the pheromones of a male mouse, most of the females will go into estrus in about 72 hours. (wikipedia.org)
  • The exposure of a recently bred mouse to the pheromones of a strange male mouse may prevent implantation (or pseudopregnancy), a phenomenon known as the Bruce effect. (wikipedia.org)
  • Newborn male mice are distinguished from newborn females by noting the greater anogenital distance and larger genital papilla in the male. (wikipedia.org)
  • Some people, however, prefer the personality and curiosity of male mice. (wikipedia.org)
  • problem
  • If they like what they find inside better than what they had outside, you will have a mouse problem. (in.gov)
  • However, you are looking at a big problem if a mouse is stuck to the same sheet your pet is. (terrificpets.com)
  • animals
  • Treated animals grew more new muscle tissue at the site of injury compared to untreated controls, and their strength after recovery rivaled that of genetically normal mice. (pitt.edu)
  • injected ISRIB into mice, the animals showed improved memory: for example, they learnt to locate a hidden platform in a water maze more rapidly than controls. (elifesciences.org)
  • Over eight out of ten animals used in research at Cambridge are mice. (cam.ac.uk)
  • Fancy mice are also called "feeder mice" when they are sold as frozen food for carnivorous pet animals such as snakes. (wikipedia.org)
  • It is a good idea to keep fancy mice in groups of at least two if possible, as mice are sociable animals. (wikipedia.org)
  • describes
  • content="NIBR researcher describes our collaboration with CASSIS, the ISS, and our research into muscle atrophy using MuRF knockout mice. (novartis.com)
  • A quote from the NMC, describes the ideal mouse body type, for showing: "The mouse must be long on body with long clean head, not too fine or pointed at the nose, the eyes should be large, bold and prominent. (wikipedia.org)
  • human
  • As a result research on mice has helped the understanding of both human physiology and the causes of disease. (cam.ac.uk)
  • The research involves a combination of tissue culture to understand cell-cell communication and genetically-modified mice to mimic human disease and to test potential new medicines. (cam.ac.uk)
  • Mice are generally very docile if raised from birth and given sufficient human contact. (wikipedia.org)
  • Lead
  • High levels of hepatic production of uPA lead to hemorrhage and death of many of the mice shortly after birth. (nih.gov)
  • large
  • Multiple large and small nodules of regenerating hepatocytes in an Alb-uPA transgenic mouse. (nih.gov)
  • These mice also have a large infraorbital foramen . (wikipedia.org)
  • Quimby states that there is large disagreement, dating back to 1899, as to how high the jumping mouse can actually jump. (wikipedia.org)
  • usually
  • The desert pocket mouse prefers various arid, open desert environments, usually where the vegetation is rather sparse. (wikipedia.org)
  • Introduction
  • In Europe the breeding of fancy mice became popular through the introduction of Japanese stock in the early 17th century. (wikipedia.org)
  • year
  • By 1895, Walter Maxey founded the National Mouse Club in Victorian England, with its first official show held in Lincoln that year. (wikipedia.org)
  • small
  • Mice are curious, and will enter any hole or crack as small as ¼-inch. (in.gov)
  • young
  • A span between cage bars of less than 9 mm (0.35 in) prevents young mice from attempting to escape by forcing themselves through the bars, where they may get stuck. (wikipedia.org)
  • together
  • Everything you need in a mouse for your PC comes together in this colorful wired offering. (asus.com)
  • help
  • Can we learn anything from mice that might help astronauts combat muscle loss in space? (novartis.com)
  • This can also help prevent predatory pets such as cats, dogs, arthropods, snakes, and other carnivores from killing and eating the mice. (wikipedia.org)
  • infection
  • The mouse cage should be cleaned every couple of days to prevent odor and disinfected properly every 2 weeks to prevent infection and disease. (wikipedia.org)
  • live
  • The mice will live in microgravity during their mission, allowing scientists to learn more about muscle development and muscle atrophy. (novartis.com)