Metoprolol adrenergic beta 1 receptor antagonists. Medical search. Frequent questions

Drugs that bind to but do not activate beta-adrenergic receptors thereby blocking the actions of beta-adrenergic agonists. (lookformedical.com)
Centrally-acting sympatholytic agent/agents (alpha2 adrenergic receptor agonists). (pharmacology2000.com)
Agonists Drugs such as dopamine that attach to and activate specific receptors. (nursekey.com)
A. Theophyllinum and beta adrenergic agonists B. Theophyllinum and beta adrenergic antagonists E. Cromolinum, nedocromilum and theophyllinum 5. (findmedarticle.com)
A. Theophyllinum B. Beta-2 adrenergic agonists C. Ipratropium D. Corticosteroides E. No positive answer 8. (findmedarticle.com)

Atenolol, a competitive beta(1)-selective adrenergic antagonist, has the lowest lipid solubility of this drug class. (druglib.com)
A beta-2 selective adrenergic antagonist. (lookformedical.com)
Non-Cardioselective Beta Blockers - Unlike selective beta-1 blockers, nonselective beta blockers target both beta-1 and beta-2 receptors. (circlemedical.com)
Metoprolol tartrate is a selective beta 1 -adrenoreceptor blocking agent, available as 25 mg, 37.5 mg, 50 mg, 75 mg and 100 mg tablets for oral administration. (pillsync.com)
Metoprolol is a beta 1 -selective (cardioselective) adrenergic receptor blocker. (pillsync.com)
Labetalol hydrochloride tablets, USP are an adrenergic receptor blocking agent that has both selective alpha 1 -adrenergic and nonselective beta-adrenergic receptor blocking actions in a single substance. (nih.gov)
Labetalol hydrochloride combines both selective, competitive, alpha 1 -adrenergic blocking and nonselective, competitive, beta-adrenergic blocking activity in a single substance. (nih.gov)
Metoprolol, a selective betai blocker approved for use in the United States, may have decreased effect on the airways. (onlineasthmainhalers.com)
Pindolol (LB-46), a potent beta-adrenergic blocker, does not have selective betai antagonism and is said to have intrinsic sympathomimetic activity. (onlineasthmainhalers.com)
SSRIs are selective to the 5-HT system but not specific for the different 5-HT receptors. (msdmanuals.com)
Cardio selective beta 1 -adrenergic blocker without internal sympathomimetic activity. (bestpharmbuy.com)
When used in moderate therapeutic doses, Betaloc ZOK has a less pronounced effect on the smooth muscles of the bronchi and peripheral arteries than non-selective beta-blockers. (bestpharmbuy.com)
Betaloc ZOK to a lesser extent affects the secretion of insulin and carbohydrate metabolism and the activity of the cardiovascular system in conditions of hypoglycemia, compared with non-selective beta-blockers. (bestpharmbuy.com)
In some cases, there was a slight decrease in the fraction of high-density lipoprotein (HDL), which is less pronounced than in the case of non-selective beta-blockers. (bestpharmbuy.com)
Sectral (acebutolol HCl) is a selective, hydrophilic beta-adrenoreceptor blocking agent with mild intrinsic sympathomimetic activity for use in treating patients with hypertension and ventricular arrhythmias . (rxlist.com)

Although it is similar to metoprolol, atenolol differs from pindolol and propranolol in that it does not have intrinsic sympathomimetic properties or membrane-stabilizing activity. (druglib.com)
Results from using an in vitro tissue bath technique indicated that propranolol and preferential beta(2)-adrenoceptor antagonists (ICI-118,551 and butoxamine), in a concentration-dependent manner, blocked the relaxation induced by nicotine (100 microM) without affecting the relaxation elicited by transmural nerve stimulation (TNS, 8 Hz). (lookformedical.com)
Propranolol is the most common beta-blocker involved in severe beta-blocker poisoning. (medscape.com)
Propranolol is a nonselective beta-blocker, demonstrating equal affinity for both beta1- and beta2-receptors. (medscape.com)
Propranolol hydrochloride is a β-adrenoceptor antagonist. (sigmaaldrich.com)
Propranolol, a nonselective beta-adrenergic blocking drug, aggravates bronchospasm in asthmatics . (onlineasthmainhalers.com)
Our decrease in mean maximal exercise heart rate with 0.4 mg of pindolol, 26 beats per minute, is close to the 29 beats per minute determined by Epstein et al in normal subjects given 0.15 mg/kg of propranolol intravenously, suggesting a comparable degree of beta-adrenergic blockade. (onlineasthmainhalers.com)
Beta blockers, such as propranolol, oxprenolol, and sotalol, are used to treat disorders of the cardiovascular system , including high blood pressure (hypertension), angina pectoris , and irregularities of heartbeat (arrhythmias). (encyclopedia.com)

Angiotensin-converting enzyme inhibitors, b-adrenergic receptor blockers and mineralocorticoid receptor antagonists target the inhibition of renin--angiotensin--aldosterone system and adrenergic nervous system and have become a standard component of therapy for heart failure (HF). (docksci.com)
6 Thus, inhibition of SNS by beta-blockers and RAAS by angiotensin converting enzyme inhibitors, angiotensin receptor blockers and mineralocorticoid receptor antagonists has become the current standard pharmacological treatment for CHF. (cfrjournal.com)

Butoxamine, an example of a beta 2 blocker, is only used in research. (wikipedia.org)
If the two drugs are coadministered, the beta blocker should be withdrawn several days before the gradual withdrawal of clonidine. (druglib.com)
If replacing clonidine by beta-blocker therapy, the introduction of beta blockers should be delayed for several days after clonidine administration has stopped. (druglib.com)
Adverse effects of beta blocker therapy can lead to fatigue, bronchospasm, depression, impotence, and attenuation of hypoglycemic symptoms in diabetic patients and worsening of congestive heart failure. (pharmacology2000.com)
The specific type of beta blocker prescribed will depend on the individual's medical condition and their response to the medication. (circlemedical.com)
A health care professional will be able to determine what is the best beta blocker for your condition based on your medical history and the condition being treated. (circlemedical.com)
High-dose thiazide therapy, beta-blocker therapy and calcium-channel blocker therapy did not significantly reduce the risk of death or coronary artery disease. (cmaj.ca)
Beta-blocker toxicity in children usually results from exposure to an adult's unattended medications. (medscape.com)
Beta-blocker toxicity in adults usually results from a suicide attempt or an accidental overdose of a routine medication. (medscape.com)
Understanding the direct and indirect effects of beta-receptor blockade is crucial to rapid identification and appropriate treatment of beta-blocker toxicity. (medscape.com)
a substantial proportion of patients with heart failure do not tolerate the doses of beta-blockers used in the large clinical trials and more than half of patients have inadequately controlled HR. For these patients, clinical evidence supports the addition of ivabradine to beta-blocker therapy. (cfrjournal.com)
In this review we summarise current findings on ivabradine therapy in CHF and advance the hypothesis, with related rationale, for combining ivabradine and beta-blocker therapy from the early stages of CHF in patients with reduced EF as an alternative strategy to up-titration of beta-blockers to an optimal dose. (cfrjournal.com)
beta blocker ( beta-adrenoceptor antagonist ) Any of a group of drugs that bind preferentially to beta adrenoceptors and hence block their stimulation by the body's own neurotransmitters, adrenaline and noradrenaline. (encyclopedia.com)
beta-blocker Any of a class of drugs that block impulses to beta nerve receptors in various tissues throughout the body, including the heart, airways, and peripheral arteries. (encyclopedia.com)
Sectral (acebutolol hydrochloride) is a beta-blocker used to treat hypertension ( high blood pressure ) and heart rhythm disorders . (rxlist.com)

Clinical pharmacology studies have demonstrated the beta-blocking activity of metoprolol, as shown by (1) reduction in heart rate and cardiac output at rest and upon exercise, (2) reduction of systolic blood pressure upon exercise, (3) inhibition of isoproterenol-induced tachycardia, and (4) reduction of reflex orthostatic tachycardia. (pillsync.com)
Chapter 1 PIXORIZE Pharmacology 2021: 1. (freemedtube.net)
PIXORIZE Pharmacology 2021: 1. (freemedtube.net)

In addition, beta-adrenergic receptor antagonism inhibits both glycogenolysis and gluconeogenesis, which may result in hypoglycemia. (medscape.com)
Acceptable beta-adrenergic antagonists for use in patients with asthma should ideally minimize antagonism of bronchial (beta2) receptors while providing useful cardiac (beta2) blockade. (onlineasthmainhalers.com)

Beta 2 -receptor blockade was demonstrated by inhibition of the isoproterenol-induced fall in diastolic blood pressure. (nih.gov)
A. Induction of metabolizing enzymes B. Displacement from serum albumin C. Inhibition of metabolizing enzyme D. Inhibition of uptake into adrenergic neuron 15. (kupdf.net)

They work by inhibiting the synthesis, release, or reuptake of the neurotransmitters or by antagonising the receptors on postsynaptic neurones. (wikipedia.org)
It works as a postsynaptic neurotoxin binding to the receptor as an extracellular ligand by interacting with OH group leaving the acetylcholine channel open which releases ions used in creating an action potential. (proteopedia.org)
Unlike most antidepressants Platin apparently does not cause reduction of functional activity of postsynaptic beta-adrenergic receptors. (sdrugs.com)
By preventing reuptake of 5-HT presynaptically, SSRIs result in more 5-HT to stimulate postsynaptic 5-HT receptors. (msdmanuals.com)

Adrenergic neurone blockers, commonly known as adrenergic antagonists, are a group of drugs that inhibit the sympathetic nervous system by blocking the activity of adrenergic neurones. (wikipedia.org)
Like metoprolol, atenolol competes with sympathomimetic neurotransmitters such as catecholamines for binding at beta(1)-adrenergic receptors in the heart and vascular smooth muscle, inhibiting sympathetic stimulation. (druglib.com)
Beta-blockers inhibit sympathetic activity and have been shown to reduce mortality in patients with heart failure with reduced ejection fraction. (medscape.com)
By binding to α2 receptors in the CNS, clonidine can modulate the release of norepinephrine, resulting in a decrease in sympathetic outflow and ultimately leading to a decrease in heart rate. (proprofs.com)
1 Activation of the sympathetic nervous system (SNS), along with activation of the renin-angiotensin-aldosterone system (RAAS), plays a fundamental role in the pathophysiology of CHF syndrome. (cfrjournal.com)
oxymetazoline topical increases and alfuzosin decreases sympathetic (adrenergic) effects, including increased blood pressure and heart rate. (medscape.com)
oxymetazoline topical and isocarboxazid both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. (medscape.com)
Instead, the major sympathetic influence on airway caliber occurs via circulating catecholamines that act primarily on the β2-receptors to produce bronchodilation. (isanagpur.org)

Antiarrhythmic effects are due mainly to beta-adrenergic receptor blockade. (pharmacology2000.com)
β-adrenergic receptor blockade can also help reduce ventricular following rates in atrial flutter and fibrillation, again by acting at the AV node. (pharmacology2000.com)
I.V. administration is used for rapid beta-receptor blockade in treatment of atrial fibrillation with high ventricular following rates. (pharmacology2000.com)
Blockade of beta-receptors results in decreased production of intracellular cyclic adenosine monophosphate (cAMP) with a resultant blunting of multiple metabolic and cardiovascular effects of circulating catecholamines. (medscape.com)
Beta1-receptor blockade reduces heart rate, blood pressure, myocardial contractility, and myocardial oxygen consumption. (medscape.com)
Beta2-receptor blockade inhibits relaxation of smooth muscle in blood vessels, bronchi, the gastrointestinal system, and the genitourinary tract. (medscape.com)
Other than the direct effects of the beta-adrenoreceptor blockade, toxicity may result from other mechanisms, including sodium and calcium channel blockade, centrally mediated cardiac depression, and alteration of cardiac myocyte energy metabolism. (medscape.com)
In man, the ratios of alpha- to beta-blockade have been estimated to be approximately 1:3 and 1:7 following oral and intravenous (IV) administration, respectively. (nih.gov)
In animals, at doses greater than those required for alpha- or beta-adrenergic blockade, a membrane-stabilizing effect has been demonstrated. (nih.gov)
Labetalol hydrochloride's beta 1 -receptor blockade in man was demonstrated by a small decrease in the resting heart rate, attenuation of tachycardia produced by isoproterenol or exercise, and by attenuation of the reflex tachycardia to the hypotension produced by amyl nitrite. (nih.gov)
We found that pindolol, given in a fixed dose of 0.4 mg intravenously, produced betai-adrenergic blockade as measured by reduction in exercise heart rate, although resting heart rates were not significantly different. (onlineasthmainhalers.com)
Calcineurin is accomplished used to use a online a companion to urban of aggregates tingling ions, Tumor difference blood, and the ventricular alpha1-beta-blockade of systemic opportunity disease. (augenta.net)

Other nonselective beta-blockers include nadolol, timolol, and pindolol. (medscape.com)

Some beta-blockers, such as pindolol and acebutolol, also have beta-agonist properties. (medscape.com)
Whether or not this activity is responsible for any relative sparing of beta2-adrenergic receptors, it is suggested that pindolol may be better tolerated in asthma and other obstructive lung diseases than other beta-adrenergic blockers. (onlineasthmainhalers.com)
Beumer and Hardonk reported on six asthmatic subjects who were given 1 mg or 2 mg of pindolol intravenously. (onlineasthmainhalers.com)

Inhibits beta-adrenergic input. (medscape.com)
The α-2 adrenergic receptor (A2AR) inhibits insulin or glucagons release. (proteopedia.org)
This preferential effect is not absolute, however, and at higher plasma concentrations, metoprolol also inhibits beta 2 adrenoreceptors, chiefly located in the bronchial and vascular musculature. (pillsync.com)

Dopamine receptors are a class of metabotropic G protein-coupled receptors that are important in the central nervous system. (proteopedia.org)
Name the drug - Dopamine receptor antagonist for the prevention of nausea and vomiting: A. Aspirinum B. Cimetidinum C. Metoclopramidum D. Erythromycinum E. Bisacodylum 10. (findmedarticle.com)

Esmolol (Brevibloc) is a very short acting, cardioselective beta-adrenergic receptor antagonist. (pharmacology2000.com)

Higher doses of atenolol also competitively block beta(2)-adrenergic responses in the bronchial and vascular smooth muscles. (druglib.com)
In contrast, preferential beta(1)-adrenoceptor antagonists (atenolol and CGP-20712A) did not affect either nicotine- or TNS-induced relaxation. (lookformedical.com)
Pressure: Atenolol works by blocking the transmission of messages to the beta receptors in the heart which slows down the activity of the heart, decreasing blood pressure. (pharmacycode.com)
Angina: Atenolol works by blocking the transmission of messages to the beta receptors in the heart which slows down the activity of the heart and reduces the heart's need for oxygen. (pharmacycode.com)

A widely used non-cardioselective beta-adrenergic antagonist. (lookformedical.com)
Cardioselective Beta Blockers - These beta blockers mainly target the beta-1 receptors found in the heart. (circlemedical.com)

They inhibit the release of circulating adrenergic neurotransmitters like norepinephrine, which contributes to the contraction of smooth muscles. (wikipedia.org)
The adrenergic beta-2 receptors are more sensitive to EPINEPHRINE than to NOREPINEPHRINE and have a high affinity for the agonist TERBUTALINE. (lookformedical.com)
The adrenergic beta-1 receptors are equally sensitive to EPINEPHRINE and NOREPINEPHRINE and bind the agonist DOBUTAMINE and the antagonist METOPROLOL with high affinity. (nih.gov)
Epinephrine, Norepinephrine, and Phenylephrine select α1 receptors agonistically. (proprofs.com)

Although their agonist property is weaker than that of catecholamines, they are capable of stimulating beta-receptors, especially when catecholamine levels are low. (medscape.com)
Beta 2 -agonist activity has been demonstrated in animals with minimal beta 1 -agonist (ISA) activity detected. (nih.gov)
The maximum effect of the drug may be produced even if not all receptors are bound in the presence of which of the following: A. Full agonist B. Partial agonist C. Spare receptors D. Inert binding site E. Effector 7. (kupdf.net)
Antagonists Drugs such as naloxone (Narcan) that attach to a specific receptor and do not activate it but instead prevent an agonist or body chemical such as a neurotransmitter from stimulating the receptor. (nursekey.com)
Competitive Antagonist Occurs when the concentration of the antagonist is higher than the agonist concentration. (nursekey.com)

Common beta-blockers used are bisoprolol and metoprolol. (medscape.com)

Beta-blockers act as competitive inhibitors of catecholamines, exerting their effects at both central and peripheral receptors. (medscape.com)

The majority of FDA-labeled uses of beta 1 blockers target the abnormalities of the heart to treat heart-related disorders including hypertension, heart failure, chronic stable angina, post-myocardial infarction, and decreased left ventricular function after a recent myocardial infarction. (wikipedia.org)
Beta blockers may exacerbate the rebound hypertension which can follow the withdrawal of clonidine. (druglib.com)
Approved for use in group 1 pulmonary arterial hypertension, there have been few trials evaluating their efficacy in group 2 pulmonary hypertension. (medscape.com)
Phosphodiesterase-5 (PDE-5) inhibitors cause smooth muscle relaxation and antiproliferative effects in the vasculature, leading to a reduction in pulmonary artery pressure in patients with WHO group 1 pulmonary hypertension. (medscape.com)
In addition to their traditional role in treating hypertension and other cardiovascular disorders, beta-blockers are also used for additional purposes such as migraine headaches, hyperthyroidism, glaucoma, anxiety, and various other disorders. (medscape.com)
With the advent of antihypertensive agents, the incidence of hypertensive emergencies in the United States has declined from 7% to approximately 1% of patients with hypertension. (medscape.com)
In older children, congestive heart failure may be caused by left-sided obstructive disease (valvar or subvalvar aortic stenosis or coarctation), myocardial dysfunction (myocarditis or cardiomyopathy), hypertension, renal failure,[1] or, more rarely, arrhythmias or myocardial ischemia. (medscape.com)
Hypertension: Start at 6.25 mg twice daily and increase if needed for blood pressure control to 12.5 mg then 25 mg twice daily over intervals of 1 to 2 weeks. (nih.gov)

Concomitant use of prostaglandin synthase inhibiting drugs, eg, indomethacin, may decrease the hypotensive effects of beta blockers. (druglib.com)
Endothelin receptor antagonists bind endothelin 1 receptors, causing a decrease in pulmonary arterial pressure through decreases in PVR. (medscape.com)
By reducing the effects of these hormones, beta blockers help to decrease the workload on the heart, allowing it to pump more efficiently and effectively. (circlemedical.com)
Metoprolol has been shown to increase postimplantation loss and decrease neonatal survival in rats at doses up to 11 times the maximum daily human dose of 450 mg, when based on surface area. (pillsync.com)
Both the alpha- and beta-blocking actions of orally administered labetalol hydrochloride contribute to a decrease in blood pressure in hypertensive patients. (nih.gov)
However, one of the clinical studies showed a significant decrease in the level of total cholesterol in the blood serum during treatment with metoprolol for several years. (bestpharmbuy.com)

Beta 1 blockers are receptor antagonists that bind to and antagonise beta 1 receptors, which are extensively located in the heart. (wikipedia.org)
Beta 1 blockers Beta 1 blockers bind to the beta 1 receptor without activating it, inhibiting the receptor-mediated effects. (wikipedia.org)
Drugs that bind to and block the activation of ADRENERGIC BETA-2 RECEPTORS. (lookformedical.com)
Drugs that selectively bind to and activate beta-adrenergic receptors. (lookformedical.com)
These drugs bind to α1 receptors and activate them, leading to vasoconstriction and increased blood pressure. (proprofs.com)
This means that while they bind to the receptor in an antagonistic manner, they also stimulate the receptor at the same time. (proprofs.com)

Acts on V2 receptors at renal tubuli, increasing cellular permeability of collecting ducts, responsible for antidiuretic effect. (medscape.com)

Catecholamine-depleting drugs (eg, reserpine) may have an additive effect when given with beta-blocking agents. (druglib.com)
Which drugs select α 1 receptors and indicate whether agonistically or antagonistically. (proprofs.com)
Ephedrine and Pseudo-Ephedrine are referred to as mixed acting drugs because they exhibit both antagonistic and stimulatory effects on their receptor simultaneously. (proprofs.com)
This dual action of the drugs on the receptor is what classifies them as mixed acting drugs. (proprofs.com)
Two drugs act on the same tissue or organ via activation of different receptors in effects that are qualitatively the opposite of one another. (kupdf.net)

Which of the following is therapeutic action of beta adrenergic receptor blockers in the treatment of angina pectoris? (kupdf.net)

Labetalol hydrochloride produces dose-related falls in blood pressure without reflex tachycardia and without significant reduction in heart rate, presumably through a mixture of its alpha blocking and beta-blocking effects. (nih.gov)
Due to the alpha 1 -receptor blocking activity of labetalol hydrochloride, blood pressure is lowered more in the standing than in the supine position, and symptoms of postural hypotension (2%), including rare instances of syncope, can occur. (nih.gov)

Minimal activity or affinity for other neurotransmitter receptors and other potential targets (eg, calcium channels). (medscape.com)

Endothelin 1 is a potent endogenous vasoconstrictor that causes vascular smooth muscle hyperplasia in addition to direct vasoconstrictor effects. (medscape.com)
While both receptors are found in the heart, beta-2 receptors are mostly found in vascular smooth muscle. (circlemedical.com)
Which calcium antagonist has highest selectivity on vascular smooth muscles? (findmedarticle.com)
Another approach increases the density of the underlying vascular network by inducing angiogenesis, and this has been accomplished through either direct delivery of vascular endothelial growth factor (VEGF) or by downregulating the VEGF decoy-receptor type 1 (VEGFR-1 or Flt-1). (biomedcentral.com)

For management of heart failure with reduced ejection fraction (HFrEF), medication classes consist of diuretics, angiotensin-receptor blockers (ARBs), angiotensin-converting enzyme (ACE) inhibitors, and beta-blockers. (medscape.com)
Four drug classes were evaluated in the trials: thiazides (21 trials), beta-adrenergic blockers (5), calcium-channel blockers (4) and angiotensin-converting-enzyme (ACE) inhibitors (1). (cmaj.ca)
first-line antihypertensive medications include angiotensin-converting enzyme inhibitors, angiotensin II receptor blockers, dihydropyridine calcium-channel blockers and thiazide diuretics. (nature.com)

As mentioned, the mechanism of action in beta blockers is blocking the effects of adrenaline in the body. (circlemedical.com)
The mechanism of the antihypertensive effects of beta-blocking agents has not been fully elucidated. (pillsync.com)
Ivabradine reduces HR via a different mechanism to beta-blockers and has been recommended in European Society of Cardiology guidelines to reduce the risk of CHF hospitalisation and cardiovascular death in symptomatic patients with EF ≤35 % who are in sinus rhythm and have a resting HR ≥70 beats per minute despite treatment with an evidence-based therapy. (cfrjournal.com)

This is the last step in the conversion of tyrosine to adrenaline [1] . (proteopedia.org)
Beta blockers are a class of medications that work by blocking the effects of adrenaline hormones. (circlemedical.com)
Your body has numerous adrenergic receptors, which are activated when naturally occurring adrenaline (aka epinephrine) is sent through the body. (circlemedical.com)

Beta blockers, also known as beta-adrenergic blocking agents, work by blocking the effects of epinephrine hormones. (circlemedical.com)

Platin is a weak antagonist of choline, adrenergic and histamine receptors. (sdrugs.com)

For G s see Beta2 adrenergic receptor-Gs protein complex updated . (proteopedia.org)

Contraindication of β-adrenergic blockers: A. 2nd or 3rd degree of heart block B. Supraventricular tachycardia C. Mitral stenosis D. Hipertensión 15. (findmedarticle.com)

Beta 2 blockers Beta 2 blockers function by prohibiting beta 2 receptor stimulation via blocking the dissociation of the alpha subunit of Gs protein and subsequent activation of adenylyl cyclase, which reduces the synthesis of cAMP and the expression of protein kinase A. This causes the levels of intracellular calcium to drop, which in turn prevents the relaxation of smooth muscles, especially the bronchial smooth muscles. (wikipedia.org)

β-adrenergic receptor blockers increase AV conduction time and increase AV nodal refractoriness, thereby helping to terminate nodal reentrant arrhythmias. (pharmacology2000.com)

The beta-3 adrenergic receptors are the predominant beta-adrenergic receptor type expressed in white and brown ADIPOCYTES and are involved in modulating ENERGY METABOLISM and THERMOGENESIS. (lookformedical.com)

When using the dosage form with a slow release of metoprolol, its bioavailability is reduced by about 20-30% compared with conventional tablets. (bestpharmbuy.com)

There are currently no FDA-approved beta 2 antagonists for clinical uses. (wikipedia.org)
Data from several studies, ie, TIMI-II, ISIS-2, currently do not suggest any clinical interaction between aspirin and beta blockers in the acute myocardial infarction setting. (druglib.com)
much of the clinical and overdose experience that exists with beta-blockers was provided by case reports and clinical studies of this drug. (medscape.com)
There is growing clinical evidence that more than half of patients with CHF who are on beta-blockers have inadequately controlled heart rate (HR) 7-11 and a substantial proportion of patients do not tolerate the target doses of beta-blockers used in the large clinical trials. (cfrjournal.com)
Due to the peculiarities of the dosage form, a constant concentration of Metoprolol in the plasma is maintained and a stable clinical effect of the drug is maintained for 24 hours. (bestpharmbuy.com)

The beta adrenergic receptors play an important role in regulating CARDIAC MUSCLE contraction, SMOOTH MUSCLE relaxation, and GLYCOGENOLYSIS. (lookformedical.com)

The β-1 adrenergic receptor (B1AR) increases cardiac output and secretion of rennin and ghrelin. (proteopedia.org)

They stimulate 5-HT 1 receptors, with antidepressant and anxiolytic effects, but they also stimulate 5-HT 2 receptors, commonly causing anxiety, insomnia, and sexual dysfunction, and 5-HT 3 receptors, commonly causing nausea and headache. (msdmanuals.com)

It stimulates both the alpha- and beta- adrenergic systems, causes systemic VASOCONSTRICTION and gastrointestinal relaxation, stimulates the HEART, and dilates BRONCHI and cerebral vessels. (lookformedical.com)
Vasopressin analogue without effect on V1 receptors responsible for vasopressin-induced vasoconstriction. (medscape.com)

The beta-1 receptor is a G-protein-coupled receptor with the Gs alpha subunit as its main signaling protein. (wikipedia.org)

Results of double-labeling studies indicated that beta(2)-adrenoceptor immunoreactivities and NADPH diaphorase reactivities were colocalized in the same nerve fibers in basilar and middle cerebral arteries. (lookformedical.com)

Beta blockers are a medication commonly used to treat various cardiovascular conditions. (circlemedical.com)
The following side effects have been reported by at least 1% of people taking this medication. (mediresource.com)

Competitive muscarinic receptor antagonist for overactive bladder, but differs from other anticholinergic types because of selectivity for urinary bladder over salivary glands. (medscape.com)
High specificity for muscarinic receptors. (medscape.com)

Competitive Antagonists of the Nicotinic Receptor. (powershow.com)
A. Physiologic C. Irreversible antagonist B. Competitive D. Chemical antagonist 5. (kupdf.net)

The adrenergic receptors are metabolic G protein-coupled receptors. (proteopedia.org)

Anatomy8

Organisms8

Diseases4

Chemicals and Drugs185

Analytical, Diagnostic and Therapeutic Techniques and Equipment17

Psychiatry and Psychology2

Phenomena and Processes15

Health Care5

Agonists5

Selective15

Propranolol8

Blockers and mineralocorticoid receptor antagonists2

Blocker15

Pharmacology3

Antagonism2

Inhibition2

Postsynaptic4

Sympathetic8

Blockade12

Timolol1

Pindolol3

Inhibits3

Dopamine2

Esmolol1

Atenolol4

Cardioselective2

Norepinephrine4

Agonist5

Bisoprolol1

Catecholamines1

Hypertension8

Decrease6

Bind6

Renal1

Drugs5

Angina pectoris1

Labetalol2

Neurotransmitter1

Vascular4

Angiotensin Conver3

Mechanism3

Adrenaline3

EPINEPHRINE1

Histamine1

Beta21

Tachycardia1

Stimulation1

Arrhythmias1

ENERGY METABOLISM1

Bioavailability1

Clinical5

GLYCOGENOLYSIS1

Cardiac output1

Anxiety1

VASOCONSTRICTION2

Signaling protein1

Nerve1

Medication2

Muscarinic2

Competitive2

Metabolic1