Methylation pattern of arabidopsis. Medical search. Frequent questions

To date, the RdDM pathway is best characterized within angiosperms (flowering plants), and particularly within the model plant Arabidopsis thaliana. (wikipedia.org)
Although the RdDM pathway has a number of important functions, RdDM-defective mutants in Arabidopsis thaliana are viable and can reproduce, which has enabled detailed genetic studies of the pathway. (wikipedia.org)
Arabidopsis thaliana methylation pattern analysis based on ONT sequence reads. (uni-bielefeld.de)
Here, we identified regulatory patterns of 16 epigenetic modifications across metabolism in Arabidopsis thaliana . (biorxiv.org)
One Sentence Summary This study identified a novel regulatory mechanism controlling specialized metabolism in Arabidopsis thaliana . (biorxiv.org)
Here, we examined this variance within Arabidopsis thaliana by evaluating SNPs for all 877 FBX loci from 432 naturally occurring accessions and their relationships to variations in natural selection, expression, and DNA/histone methylation. (nih.gov)
pp. 710-724) demonstrated that a pathogen-derived Ralstonia pseudosolanacearum type III effector RipL delays flowering time and enhances susceptibility to bacterial infection in Arabidopsis thaliana . (molcells.org)
Dynamic changes in genome-wide histone H3 lysine 4 methylation patterns in response to dehydration stress in Arabidopsis thaliana. (refine.bio)
These microarrays are part of a study where a comparison was made between the change in transcription and H3K4 mono-, di-, and tri-methylation levels (via ChIP-seq) in the Arabidopsis thaliana genome when plants are subjected to water deficit stress. (refine.bio)
Transduction of RNA-directed DNA methylation signals to repressive histone marks in Arabidopsis thaliana. (omicsdi.org)
In this study, we analysed the mechanism of gene silencing mediated by MORPHEUS' MOLECULE1 (MOM1) of Arabidopsis thaliana. (omicsdi.org)
We performed a methylation-sensitive amplification polymorphism analysis to search for targets of RNA-directed DNA methylation in Arabidopsis thaliana and identified several members of a gene family encoding cysteine-rich peptides (CRPs). (biomedcentral.com)
This study identified the cotton DNA demethylasegene family and analyzed it using bioinformatics methods to lay the foundation for further study of cottondemethylase gene function.Results: This study used genomic information from diploid Gossypium raimondii JGI (D), Gossypium arboreum L. CRI(A), Gossypium hirsutum L. JGI (AD1) and Gossypium barbadebse L. NAU (AD2) to Arabidopsis thaliana. (zbook.org)
Examples are mouse Mus musculus , the worm Cenorhabditis elegans , the yeast Saccharomyces cerevisiae , mouse-ear cress plants Arabidopsis thaliana and the fruitfly, Drosophila melanogaster . (epigenome-noe.net)
Jacobsen, who has done extensive research on the epigenetics of Arabidopsis thaliana , gave a talk in an earlier session on the genome-wide DNA methylation analysis of a panel of 86 Arabidopsis silencing mutants. (biomedcentral.com)
AcGXs are the predominant type of xylan found within the thick lignified secondary cell walls of hardwoods and herbaceous dicot species such as Poplar and the model plant Arabidopsis thaliana (Fig. 1 ) [ 11 , 12 , 13 ]. (biomedcentral.com)
Mutation bias reflects natural selection in Arabidopsis thaliana . (zeagenomics.org)

Enrichment of modifications in each metabolic domain, relative to all the genes in the genome, revealed both shared and diverse patterns. (biorxiv.org)
In contrast, metabolic genes involved in specialized and hormone metabolic domains, which are generally involved in interactions with biotic and abiotic environmental stimuli, showed distinct patterns with the enrichment of a repression mark H3K27me3 and an activation mark H3K18ac ( Fig. 1B ). (biorxiv.org)
The enrichment patterns of epigenetic modifications were consistent with expression levels of genes involved in each domain under healthy conditions (Fig. S1A). (biorxiv.org)
Here, I generated 15 transgenic Arabidopsis GUS reporter lines for genes involved in DNA methylation and demethylation pathways. (tennessee.edu)
The spatiotemporal expression patterns of these genes were profiled in various plant organs during development, exogenous phytohormone response, and plant-parasitic nematode pathogenesis. (tennessee.edu)
Summary description of changes in promoter activity of DNA methylation and demethylation-related genes in two-week-old roots in response to phytohormone treatments. (tennessee.edu)
In contrast, the Lineage-Specific and Pseudo groups are enriched in genes with basal expression and higher SNP density and more correlated with methylation marks (RNA-directed DNA methylation and histone H3K27 trimethylation) that promote transcriptional silencing. (nih.gov)
In plants RNA interference or post transcriptional gene silencing (PTGS) acts as a natural anti-viral defense system for neutralizing pathogenic nucleic acids either through a change in RNA stability in the cytoplasm or through mechanisms that use the RNA itself to induce methylation and silencing of homologous nuclear genes [ 1 ]. (biomedcentral.com)
Excerpt 1) "A recent study demonstrated that the DNA methylation in promoter may play a significant role for functional divergence of duplicated genes in human [48] . (scentoferos.com)
This refutes the idea that [RNA-directed] DNA methylation of genes is strictly determined in a tissue-by-tissue manner and indicates the presence of a common developmental programming underlying regulation of duplicate genes across divergent cell types. (scentoferos.com)
Despite the presence of centromeric 24-nt siRNAs, mutations in genes required for RdDM do not appreciably influence the methylation of centromeric repeats. (omicsdi.org)
By contrast, many protein-coding genes transcribed by Pol II contain in their gene bodies exclusively CG methylation that is independent of small RNAs and Pol IV/Pol V activities. (biomedcentral.com)
It is unclear how the different methylation machineries distinguish between transposons and genes. (biomedcentral.com)
Here we report on a group of atypical genes that display in their coding region a transposon-like methylation pattern, which is associated with gene silencing in sporophytic tissues. (biomedcentral.com)
In leaves, the CRP genes are silent and their coding regions contain dense, transposon-like methylation in CG, CHG and CHH contexts, which depends partly on the Pol IV/Pol V pathway and small RNAs. (biomedcentral.com)
Methylation in the coding region is reduced, however, in the synergid cells of the female gametophyte, where the CRP genes are specifically expressed. (biomedcentral.com)
Further demonstrating that expressed CRP genes lack gene body methylation, a CRP4-GFP fusion gene under the control of the constitutive 35 S promoter remains unmethylated in leaves and is transcribed to produce a translatable mRNA. (biomedcentral.com)
We discuss this unusual methylation pattern and its alteration in synergid cells as well as the possible retrogene origin and evolutionary significance of CRP genes that are methylated like transposons. (biomedcentral.com)
Using DNAdemethylase genes sequence of Arabidopsis as reference, 25 DNA demethylase genes were identified in cotton byBLAST analysis. (zbook.org)
When Arabidopsis plants were exposed to cold temperature, H3K27me3 was significantly reduced in the area of chromatin containing COR15A (Cold-regulated15A) and ATGOLS3 (Galactinol Synthase 3) 17, which are cold stress response genes. (achrinhibitor.com)
Alterations in DNA methylation, lncRNAs and multiple genes may be involved in the regulation of FTLs . (nature.com)

Cytosine C5 methylation is an important epigenetic control mechanism in a wide array of eukaryotic organisms and generally carried out by proteins of the C-5 DNA methyltransferase family (DNMTs). (mdpi.com)
In eukaryotes, DNA methylation refers to the addition of a methyl group to the fifth atom in the six-atom ring of cytosine residues. (degruyter.com)
In plants, cytosine methylation is an additional factor regulating inactive chromatin, but the mechanisms regulating the coexistence of cytosine methylation and repressive histone modification remain obscure. (omicsdi.org)
Analysis of a single-copy gene, SUPPRESSOR OF drm1 drm2 cmt3 (SDC), revealed that mom1 activates SDC with concomitant reduction of di-methylated histone H3 lysine 9 (H3K9me2) at the tandem repeats in the promoter region without changes in siRNA accumulation and cytosine methylation. (omicsdi.org)
Histones and DNAs in heterochromatin have characteristic features with abundant H3H9me2 and cytosine methylation, respectively. (omicsdi.org)
Plants have evolved a complex transcriptional machinery for generating and using small RNAs that guide DNA cytosine methylation at homologous regions of the genome. (biomedcentral.com)
The Arabidopsis SUVH household proteins appear to be recruited to target loci by preferential binding to methylated cytosine by way of a SET- and RING-associated (SRA) domain (Arita et al. (pi4kinhibitor.com)
2009). Mutation from the gene encoding histone H3 acetyltransferase, Improved DNA METHYLATION 1 (IDM1), in Arabidopsis also outcomes in elevated levels of cytosine methylation (Qian et al. (pi4kinhibitor.com)
Most ofthe DNA methylation occur on the fifth carbon atom(C5) of the cytosine in the symmetrical CG site, butalso exsits in the CHG and CHH (H A, C or T) sequences in plants (Stroud et al. (zbook.org)
Lister, R., Ecker, J.R.: Finding the fifth base: genome-wide sequencing of cytosine methylation. (zbmath.org)
In DNA methylation occurs mainly at CpG sites (where a cytosine is followed by a guanine in the DNA sequence ). (epigenome-noe.net)

In Arabidopsis, trimethylation of lysine 36 in histone 3 (H3K36me3) activates energy related pathways ( 3 ) and trimethylation of lysine 27 in histone 3 (H3K27me3) represses lipid biosynthesis pathways ( 4 ). (biorxiv.org)
2012). MET1 has an essential function in preserving histone H3 Lys 27 trimethylation (H3K27me3) patterning at certain loci (Deleris et al. (pi4kinhibitor.com)
By establishing the trimethylation pattern of H3K4me3 residues of the nucleosomes, ATX1/SDG27 (Arabidopsis Homolog of Trithorax) regulates the SA/JA signaling pathway for plant defense against bacterial pathogens by activating the expression of the WRKY70, which was a critical transcription factor15. (achrinhibitor.com)

VN show greatly reduced H3K9me2, phenocopying nuclei carrying a mutation in the chromatin remodeller DECREASE IN DNA METHYLATION 1 (DDM1). (omicsdi.org)
We hypothesize that CDCA7 becomes dispensable in species that lost HELLS or DNA methylation, and/or the loss of CDCA7 triggers the replacement of DNA methylation by other chromatin regulation mechanisms. (elifesciences.org)
DNA methylation levels and specific histone modifications of chromatin in interphase nuclei are taken as an indicator of transcriptional activity or silencing. (hal.science)
Mutant ddm1, representing the first type, lacks a chromatin remodeling factor that regulates histone and DNA methylation. (hal.science)

At least in plants, DNA regions that become de novo methylated can be defined by homologous RNA molecules in a process termed RNA-directed DNA methylation (RdDM). (degruyter.com)

In the ddm1 (decrease in DNA methylation 1) mutants, their transcriptional activation is accompanied by the expected shift in the H3 modifications--depletion of H3K9me2 and enrichment in H3K4me2. (omicsdi.org)
Arabidopsis mutants impaired in maintenance of transcriptional gene silencing (TGS) alleviate TGS with or without affecting DNA methylation. (hal.science)

Previous phylogenetic comparisons based on orthology, diversity, and expression patterns identified three plant FBX groups--Common, Lineage-Specific, and Pseudo(genized)--whose emergences are consistent with genomic drift evolution. (nih.gov)
Pol IV is needed to produce the small RNA trigger for methylation whereas Pol V acts downstream of small RNA biogenesis to facilitate de novo methylation of genomic DNA at the small RNA-targeted site. (biomedcentral.com)
To investigate the chronological age of bamboo from the genomic DNA methylation profile, methylation-sensitive amplification polymorphism (MSAP) was employed to analyze the genomic DNA methylation of Moso bamboo ( Phyllostachys heterocycla var. (springeropen.com)
The results showed that the total genomic DNA methylation rates in Moso bamboo at different chronological ages were significantly different, and the increase in genomic DNA methylation rate was consistent with the increase of chronological age. (springeropen.com)
An integrated index was obtained by performing principal component analysis on the six primer pairs to represent the genomic DNA methylation levels in Moso bamboo of various chronological ages, and a quadratic curve between the chronological age and genomic DNA methylation levels was obtained. (springeropen.com)
2005 ). Our previous studies on 5-year-old, 31-year-old and over 60-year-old Moso bamboo showed that significant differences existed in the genomic DNA methylation levels in Moso bamboo at different chronological ages and the levels increase with age (Guo et al. (springeropen.com)
Genomic methylation patterns in archaeological barley show de-methylation as a time-dependent diagenetic process. (zeagenomics.org)
Concerted genomic and epigenomic changes accompany stabilization of Arabidopsis allopolyploids. (zeagenomics.org)

The recruitment of this machinery results in the production of viroid-derived small RNAs (vd-sRNAs) that mediate RNA degradation and DNA methylation of cognate sequences. (degruyter.com)
RNA-directed DNA methylation (RdDM) is a process that uses 24-nucleotide (nt) small interfering RNAs (siRNAs) to induce de novo methylation to its homologous DNA sequences. (omicsdi.org)
This pattern of methylation is mediated in part by small RNAs and two specialized RNA polymerases, termed Pol IV and Pol V, in a process called RNA-directed DNA methylation. (biomedcentral.com)
In a current model, Pol V synthesizes scaffold transcripts that interact with ARGONAUTE4-bound small RNAs, which recruits the methylation machinery to the target DNA [ 3 ]. (biomedcentral.com)

The DNA methylation added by RdDM is generally associated with transcriptional repression of the genetic sequences targeted by the pathway. (wikipedia.org)
Epigenetic mechanisms, including histone and DNA methylation and microRNAs, play key roles in mediating transcriptional changes during plant development and stress responses. (tennessee.edu)
Shown is the RipL-expressing Arabidopsis plant, which displays general dampening of the transcriptional program during pathogen infection, grown in long-day conditions. (molcells.org)
However, unlike the situation in ddm1 nuclei, the decondensed heterochromatin retains dense CG methylation and transcriptional silencing, and, unexpectedly, is subjected to RdDM-dependent hypermethylation in non-CG contexts. (omicsdi.org)
In euchromatin, methylation of histone H3K4, H3K36 and H3K27me3 were shown to be associated with gene regulations including transcriptional activation and gene silencing13. (achrinhibitor.com)

The de novo DNA methylation and an increased proportion of histone H3 Lysine-9 methylation (H3K9) at intergenic region (IGR) of ACMV DNA A were observed. (biomedcentral.com)
Here I show multiple siRNAs species in transgenic plants direct the methylation of ACMV DNA A as well as the methylation at lysine-9 residues of histone H3 wrapping the promoter region in the virus genome. (biomedcentral.com)
In Arabidopsis, constitutive heterochromatin is characterized by hypermethylated DNA and histone H3 dimethylated at lysine (K) 9 (H3K9me2) together with depletion of histone H3 dimethylated at lysine 4 (H3K4me2). (omicsdi.org)
The pattern of how particular amino acids are methylated within an array of nucleosomes , e.g. a lysine or arginine can be mono-, bi- or trimethylated deciding about the degree of heterochromatin isation. (epigenome-noe.net)
For example, phosphorylation mainly occurs on a subset of three types of amino acids, including serine (S), threonine (T) and tyrosine (Y). Methylation is predominantly found on lysine (K) and arginine (R) residues. (deepdyve.com)

Although the RdDM mechanism itself is unique to plants, using DNA methylation to silence TEs is a common strategy among eukaryotes. (wikipedia.org)
The results suggest that the roles for the two factors in DNA methylation maintenance pathways can be traced back to the last eukaryotic common ancestor and that the CDC7A-HELLS-DNMT axis shaped the evolutionary retention of DNA methylation in eukaryotes. (elifesciences.org)
DNA methylation, particularly 5-methylcytosine (5mC) at CpG sequences, is widely conserved in eukaryotes. (elifesciences.org)

RNA-directed DNA methylation (RdDM) is a biological process in which non-coding RNA molecules direct the addition of DNA methylation to specific DNA sequences. (wikipedia.org)
Overall, RdDM is an important pathway in plants that regulates a number of processes by establishing and reinforcing specific DNA methylation patterns, which can lead to transgenerational epigenetic effects on gene expression and phenotype. (wikipedia.org)
RdDM plays a key role in silencing these mobile DNA elements in plants by adding DNA methylation over new TE insertions and constantly reinforcing DNA methylation over existing TEs, inhibiting transposition and maintaining long-term genome stability. (wikipedia.org)
Since then, he has been working as a postodoc in Dr. Wassenegger's lab (RLP AgroScience GmbH, AlPlanta) and his main field of interest is RNA-interference (RNAi) and RNA-directed DNA methylation (RdDM) in plants. (degruyter.com)
Transcript profiling revealed that the majority of up-regulated loci in mom1 carry sequences related to transposons and homologous to the 24-nt siRNAs accumulated in wild-type plants that are the hallmarks of RNA-directed DNA methylation (RdDM). (omicsdi.org)

To determine how metabolism is regulated epigenetically, we first identified regulatory patterns of epigenetic modification across all metabolic domains. (biorxiv.org)
DNA methylation is the major heritable epigenetic modification and contributes to the epigenetic regulation of nuclear gene expression and genome stability [ 13 ]. (biomedcentral.com)
Journal of Cotton Research(2019) 2:16BackgroundDNA methylation is an epigenetic modification widelyfound in bacteria, plants and animals (Chen et al. (zbook.org)

Furthermore, methylation sequencing results showed that LPSN caused massive gene methylation changes, which enriched in over 20 GO pathways in the filial overexpression line, and the expression of OsNAR2.1 in LPSN filial overexpression plants was significantly reduced compared to HPSN filial plants in high external N, which was not shown in wild type. (biomedcentral.com)
2018). DNA methylationis regulated by different pathways to establish methylation and reverse methylation (Ja and Se 2010). (zbook.org)

10] reported that the K36M mutation of H3 impairs the differentiation of mesenchymal progenitor cells and promotes undifferentiated sarcoma through altered histone methylation landscape. (deepdyve.com)

His fields of research comprise RNA-mediated gene silencing processes with a focus on epigenetic phenomena, including studies on RNA-directed DNA methylation, the characterization of virus silencing suppressor proteins, the development of plant bioreactor platforms and viroid research. (degruyter.com)
2008). Several lines of evidence support that molecular coupling of DNA methylation and histone modification may well be partially mediated through methylcytosine-binding proteins. (pi4kinhibitor.com)
2008). Arabidopsis homologs of UHRF1, the VARIANT IN METHYLATION/ORTHRUS (VIM/ORTH) household proteins, also function as methylcytosine-binding proteins (Johnson et al. (pi4kinhibitor.com)
2007). The VIM proteins are involved inside the regulation of DNA methylation and epigenetic gene silencing at heterochromatic regions (Woo et al. (pi4kinhibitor.com)
Studies involving Arabidopsis VIM proteins enhanced our understanding of the mechanistic basis for VIMmediated epigenetic gene silencing. (pi4kinhibitor.com)
By regulating H3K36 methylation of histone proteins in JA (jasmonic acid) and/or ethylene13 and brassinosteroids signaling pathway, Arabidopsis SDG8 (SET Domain Group 8) was shown to play a critical role against fungal pathogens MK-1439 web Alternaria brassicicola and Botrytis cinerea16. (achrinhibitor.com)

Additionally, SUVH5/6-mediated H3K9 dimethylation associates with CG methylation in response to H. schachtii . (tennessee.edu)
2011). Moreover, a genome-wide evaluation demonstrated a powerful correlation involving DNA methylation and H3K9 methylation (Bernatavichute et al. (pi4kinhibitor.com)

Induction of RNA-directed DNA methylation upon decondensation of constitutive heterochromatin. (omicsdi.org)
Centromeric constitutive heterochromatin is marked by DNA methylation and dimethylated histone H3 Lys 9 (H3K9me2) in Arabidopsis. (omicsdi.org)
In Arabidopsis, the major heterchromatin regions are present at around centromeres (pericentromeric regions) and at a region on the short arm of chromosome 4 (heterochromatin knob). (omicsdi.org)
In htz1Delta cells, Sir2 and Sir3 spread into flanking euchromatic regions, producing changes in histone H4 acetylation and H3 4-methylation indicative of ectopic heterochromatin formation. (sdbonline.org)
The ddm1 mutation causes a striking decondensation of centromeric heterochromatin, a re-distribution of the remaining methylation of DNA, and a drastic change in the pattern of histone modification. (hal.science)

Journal of Cotton Research(2019) RCHJournal of Cotton ResearchOpen AccessGenome-wide identification and expressionanalysis of DNA demethylase family incottonYANG Xiaomin, LU Xuke, CHEN Xiugui, WANG Delong, WANG Junjuan, WANG Shuai, GUO Lixue, CHEN Chao,WANG Xiaoge, WANG Xinlei and YE Wuwei*AbstractBackground: DNA methylation is an important epigenetic factor that maintains and regulates gene expression. (zbook.org)

This unique expression pattern links p4-siRNAs to double fertilization, parental genome interactions and imprinted gene expression. (arizona.edu)
Mosher, RA 2010, ' Maternal control of Pol IV-dependent siRNAs in Arabidopsis endosperm ', New Phytologist , vol. 186, no. 2, pp. 358-364. (arizona.edu)

By profiling DNA methylation patterns of individual callus-derived lines, Jacobsen's group showed that regenerants lose methylation relative to parental plants, and that loss typically occurs in certain regions of the genome (although the exact pattern differs among regenerated plants). (biomedcentral.com)

In plants, transposons and non-protein-coding repeats are epigenetically silenced by CG and non-CG methylation. (biomedcentral.com)

In addition, a recent genome-wide DNA methylome analysis revealed that CG and CHG methylation was strongly decreased inside the vim1 vim2 vim3 triple mutant (hereafter designated vim1/2/3) (Stroud et al. (pi4kinhibitor.com)

In our research, overexpression of the OsNAR2.1 line was used as a testing target in rice plants with high nitrogen-use efficiency to study the changes of rice methylation and growth in respond of the endogenous and external nitrogen stress. (biomedcentral.com)
By contrast, a CRP4-GFP fusion gene under the control of a CRP4 promoter fragment acquires CG and non-CG methylation in the CRP coding region in leaves similar to the silent endogenous CRP4 gene. (biomedcentral.com)

We conclude by introducing our recent work on UNI, a novel R protein in Arabidopsis which mediates cross-talk between developmental processes and defense responses. (molcells.org)
DNA methylation mediates organisms' adaptations to environmental changes in a wide range of species. (mdpi.com)

Specifically, we examined 16 high-resolution epigenomic profiles, including histone variants, DNA methylation, and histone modifications ( 5 ). (biorxiv.org)
Finally, the regulatory mechanism through which miR778 induces histone modifications, DNA methylation, and transcriptome reprogramming during H. schachtii parasitism of Arabidopsis was investigated. (tennessee.edu)
DNA methylation and histone modifications play a central role in the epigenetic regulation of gene expression and cell differentiation. (cipsm.de)

Excerpt 2) "In human, a exclusive relationship of gene body [RNA-directed] DNA methylation with evolutionary and expression divergence of paralogs could not be revealed [48] . (scentoferos.com)

RNA-directed DNA methylation results in a characteristic modification pattern that is typified by methylation of cytosines in all sequence contexts (CG, CHG and CHH, where H is A, T or C) within the region of small RNA-DNA sequence homology [ 4 ]. (biomedcentral.com)
2011). A further instance of molecular linker in between DNA methylation and histone modification is usually a JmjC domain-containing histone demethylase, Improved IN BONSAI METHYLATION 1 (IBM1). (pi4kinhibitor.com)

Could the emergence or loss of a specific nucleosome regulator affect the evolution of DNA methylation as an epigenetic mechanism? (elifesciences.org)

This important manuscript reveals signatures of co-evolution of two nucleosome remodeling factors, Lsh/HELLS and CDCA7, which are involved in the regulation of eukaryotic DNA methylation. (elifesciences.org)

An Arabidopsis mutation defective in IBM1 JAK2 Inhibitor Purity & Documentation causes elevated histone H3 Lys 9 dimethylation (H3K9me2) levels and concomitant CHG hypermethylation (Saze et al. (pi4kinhibitor.com)

These AcGXs are homodisperse in length (approximately 100 residues in Arabidopsis ) and, on average, one of every ten xylosyl residues is substituted at O -2 with (4- O -methyl)-α- d -glucuronic acid((Me)Glc p A) [ 13 , 14 ]. (biomedcentral.com)

Since DNA methylation patterns in plants are heritable, these changes can often be stably transmitted to progeny. (wikipedia.org)
After they have automagically appeared, the enzymes lead to DNA methylation, which is associated with mutations, natural selection, and the evolution of biodiversity in plants. (scentoferos.com)
The enzymes, which automagically appear, are not associated with nutrient uptake or with nutrient-dependent RNA-directed DNA methylation and RNA-mediated events that link amino acid substitutions to cell type differentiation in plants and animals via biophysically-contrained protein folding. (scentoferos.com)

Themode and level of DNA methylation depend on the roles of DNA methyltransferase and demethylase, while DNAdemethylase plays a key role in the process of DNA demethylation. (zbook.org)

it remains unclear if there is any common process or event that leads to the loss of DNA methylation systems in certain evolutionary lineages. (elifesciences.org)

We suggest that the parent seed nitrogen content decreased induced DNA methylation changes at the epigenetic level and significantly decreased the expression of OsNAR2.1 , resulting in a heritable phenotype of N deficiency over two generations of the overexpression line. (biomedcentral.com)

Public data sets used in this study include PRJNA298638 (rice TRAP-seq) 13 , SRP043448 (rice small RNA-seq) 15 and GSE52952 ( Arabidopsis small RNA-seq and degradome-seq) 17 . (nature.com)

Mutations in HELLS, its activator CDCA7, and the de novo DNA methyltransferase DNMT3B, cause immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome, a genetic disorder associated with the loss of DNA methylation. (elifesciences.org)

Correlation between DNA methylation and chronological age of Moso bamboo (Phyllostachys heterocycla var. (springeropen.com)

These results suggest methylation-dependent mechanisms similarly and differentially regulate plant responses to infection by two distinct nematode species. (tennessee.edu)

Unlike CG methylation in gene bodies, which does not dramatically affect Pol II transcription, combined CG and non-CG methylation in CRP coding regions is likely to contribute to gene silencing in leaves because loss of this methylation in synergid cells is associated with CRP gene expression. (biomedcentral.com)

In the syncytia and galls formed by the cyst ( Heterodera schachtii ) and the root-knot ( Meloidogyne incognita ) nematodes, respectively, CG and non-CG methyltransferases exhibited similar and distinct expression patterns at various stage of infection. (tennessee.edu)

2013). DNA methylation is a necessary setup for the normal growth and development of organisms. (zbook.org)

Laird, P.W.: Principles and challenges of genomewide DNA methylation analysis. (zbmath.org)
Coevolution of presence-absence patterns (CoPAP) analysis in Ecdysozoa further indicates coevolutionary linkages among CDCA7, HELLS, DNMT1 and its activator UHRF1. (elifesciences.org)

Anatomy41

Organisms13

Diseases7

Chemicals and Drugs88

Analytical, Diagnostic and Therapeutic Techniques and Equipment22

Phenomena and Processes90

Disciplines and Occupations3

Technology, Industry, Agriculture4

Information Science4

Health Care4

Thaliana17

Genes21

Cytosine11

Trimethylation3

Chromatin4

Termed RNA-directed DNA methylation1

Mutants2

Genomic8

RNAs4

Transcriptional5

Lysine5

Eukaryotes3

RdDM5

Epigenetic modification3

Pathways2

Histone methylation1

Proteins6

H3K92

Heterochromatin5

Important epigenetic1

SiRNAs2

Regions of the genome1

Transposons1

Methylome1

Endogenous2

Mediates2

Modifications3

Gene body1

Modification2

Mechanism1

Regulation1

Mutation1

Residues1

Plants3

Demethylase1

Evolutionary1

Heritable1

Rice1

Centromeric1

Correlation1

Mechanisms1

Transcription1

Methyltransferases1

Organisms1

Analysis2