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  • Cheng
  • A consortium of scientists, led by Albert Jeltsch at Jacobs University, Breman, Germany, Yoichi Shinkai at Kyoto University, Japan, and Xiaodong Cheng at Emory University, has now discovered new non-histone targets for one enzyme previously believed to modify only histones--the group of proteins that creates tightly bundled packages of DNA strands. (emory.edu)
  • mutations
  • DNA mutations originate from changes in the nucleotide sequence mainly derived from insertions, deletions, point mutations and chromosomal translocations that influence the normal balance between cellular proliferation and death. (omicsonline.org)
  • represses
  • The open chain histone confirmation shows permissive nature whereas closed confirmation represses the process of transcription [ 8 ]. (omicsonline.org)
  • function
  • Growing and developing tissues are particularly vulnerable to alcohol's influence, suggesting that stem- and progenitor-cell function could be affected. (springer.com)