Methyl 2 cyanoacrylate monomer cyanoacrylates. Medical search. Frequent questions

Cyanoacrylates are a family of strong fast-acting adhesives with industrial, medical, and household uses. (wikipedia.org)
Cyanoacrylate adhesives are sometimes known generically as instant glues, power glues or superglues. (wikipedia.org)
Cyanoacrylate adhesives have a short shelf life-about one year from manufacture if unopened, and one month once opened. (wikipedia.org)
Cyanoacrylates are mainly used as adhesives. (wikipedia.org)
The accelerator is designed to speed the cure of Hernon cyanoacrylate adhesives. (hernon.com)
Accelerator 48 is used where increased cure speed of Hernon® cyanoacrylate adhesives is required. (hernon.com)
Accelerator 52 is a single component, non-CFC solvent based adhesive accelerator formulated to promote the cure speed of Hernon cyanoacrylate adhesives. (hernon.com)

Specific cyanoacrylates include methyl 2-cyanoacrylate (MCA), ethyl 2-cyanoacrylate (ECA, commonly sold under trade names such as "Super Glue" and "Krazy Glue"), n-butyl cyanoacrylate (n-BCA), octyl cyanoacrylate, and 2-octyl cyanoacrylate (used in medical, veterinary and first aid applications). (wikipedia.org)

Cyanoacrylate was first discovered in 1942 by Harry Coover and Fred Joyner at the Kodak research laboratories in Tennessee, but it wasn't until 1958 that methyl-2-cyanoacrylate (sold under the name "Eastman #910") was released as the first commercially available cyanoacrylate derivative, or what is commonly termed "Super Glue. (medscape.com)
Previously, butyl-2-cyanoacrylate was the only commercially available cyanoacrylate tissue adhesive. (medscape.com)

In the US, due to its potential to irritate the skin, the U.S. Food and Drug Administration (FDA) did not approve its use as a medical adhesive until 1998 with Dermabond (2-octyl cyanoacrylate). (wikipedia.org)
The wound adhesive 2-octyl cyanoacrylate (Dermabond) is approved by the US Food and Drug Administration (FDA) for the closure of incised skin. (medscape.com)
The polymer 2-octyl cyanoacrylate (Dermabond) was formulated to correct some of the deficiencies of the shorter-chain cyanoacrylate derivatives. (medscape.com)

Combined with weakly alkaline materials, the monomers rapidly polymerize via an exothermic reaction to form a clear, solid, waterproof substance. (medscape.com)
Upon application to living tissues (water or base), the monomer undergoes an exothermic hydroxylation reaction that results in polymerization of the adhesive. (medscape.com)

Specific cyanoacrylates include methyl 2-cyanoacrylate (MCA), ethyl 2-cyanoacrylate (ECA, commonly sold under trade names such as "Super Glue" and "Krazy Glue"), n-butyl cyanoacrylate (n-BCA), octyl cyanoacrylate, and 2-octyl cyanoacrylate (used in medical, veterinary and first aid applications). (wikipedia.org)
[ 1 ] In addition to its surgical adhesive indication, 2-octyl cyanoacrylate was approved by the FDA in January 2001 for use as a barrier against common bacterial microbes, including certain staphylococci, pseudomonads, and Escherichia coli . (medscape.com)
The slower degradation of the octyl derivatives may result in lower concentrations of the cyanoacrylate polymer byproducts in surrounding tissues, resulting in less inflammation. (medscape.com)
The three-dimensional (3-D) breaking strength of 2-octyl cyanoacrylate is three times that of butyl-2-cyanoacrylate and is closer to that of a 5-0 monofilament suture. (medscape.com)

Cyanoacrylate glue has a low shearing strength, which has led to its use as a temporary adhesive in cases where the piece needs to be sheared off later. (wikipedia.org)
Cyanoacrylate glue is widely used in human and veterinary medicine. (wikipedia.org)
The authors present 2 cases of cyanoacrylate glue ("Super Glue") burns, with a review of the literature and a discussion on the mechanism of action. (medscape.com)
The authors found all reported cases were with domestic - not medical-grade - cyanoacrylate glue in the presence of cotton fabric. (medscape.com)

Although cyanoacrylate glues are so useful due to the high speed of curing, they can also cause problems: the faster the adhesive cures, the higher the local temperature. (medscape.com)

Cyanoacrylate adhesives are sometimes known generically as instant glues, power glues or superglues. (wikipedia.org)
The authors identify factors that explain the different risk profiles of domestic and medical cyanoacrylate glues and could be addressed to improve safety with nonmedical applications. (medscape.com)

Butyl-2-cyanoacrylate has been used widely with good cosmetic outcomes for various plastic surgical procedures (eg, upper lid blepharoplasty, facial skin closure, scalp wound closure). (medscape.com)

Cyanoacrylates are organic monomers, which are liquids at room temperature. (medscape.com)
Industrial hygiene surveys were conducted over two days in April 1993, and over one day in August 1993, to measure the airborne concentration of several chemicals used in the laboratory, including methylene chloride, methyl methacrylate, cyanoacrylates, and various organic solvents. (cdc.gov)

The team quickly rejected the substance for the wartime application, but in 1951, while working as researchers for Eastman Kodak, Coover and a colleague, Fred Joyner, rediscovered cyanoacrylates. (wikipedia.org)
Loctite quickly gained market share, and by the late 1970s it was believed to have exceeded Eastman Kodak's share in the North American industrial cyanoacrylate market. (wikipedia.org)
National Starch and Chemical Company purchased Eastman Kodak's cyanoacrylate business and combined it with several acquisitions made throughout the 1970s forming Permabond. (wikipedia.org)
Together, Loctite, Eastman, and Permabond accounted for approximately 75% of the industrial cyanoacrylate market. (wikipedia.org)

hence, cyanoacrylates are applied as thin coats to ensure that the reaction proceeds rapidly for bonding. (wikipedia.org)

The cyanoacrylate group in the monomer rapidly polymerizes in the presence of water to form long, strong chains. (wikipedia.org)

A cyanoacrylate spray was used in the Vietnam War to reduce bleeding in wounded soldiers until they could be taken to a hospital. (wikipedia.org)

The abbreviation "CA" is commonly used for industrial grade cyanoacrylate. (wikipedia.org)

The molecule is formed by 2 highly polarized subunits, a cyano group and an ester, formed by an acryl acid and a variable alcohol (eg, methanol in methyl-2-cyanoacrylate) and a central carbon atom with a double bond, which breaks during polymerization to form long-chain macromolecules (Figure 2). (medscape.com)

The original patent for cyanoacrylate was filed in 1947 by the B.F. Goodrich Company as an outgrowth of a search for materials suitable for clear plastic gun sights for the war effort. (wikipedia.org)
Other manufacturers of cyanoacrylate include LePage (a Canadian company acquired by Henkel in 1996), the Permabond Division of National Starch and Chemical, which was a subsidiary of Unilever. (wikipedia.org)

a good example of this is the fact that cyanoacrylates may be removed from human skin by means of abrasives (e.g. sugar or sandpaper). (wikipedia.org)