• Here, we demonstrate that NK cells (haNKs) engineered to express a PD-L1 chimeric antigen receptor (CAR) haNKs killed a panel of human and murine head and neck cancer cells at low effector-to-target ratios in a PD-L1-dependent fashion. (elifesciences.org)
  • Here, we describe the pre-clinical in vitro and in vivo study of irradiated haNK cells engineered to express a second-generation chimeric antigen receptor (CAR) targeting programmed death-ligand 1 (PD-L1). (elifesciences.org)
  • Chimeric antigen receptor (CAR) T-cell therapy is a rapidly growing treatment modality. (medscape.com)
  • The development of immunoglobulin receptor repertoire sequencing methods makes it possible to perform repertoire-wide disease association studies of antigen receptor sequences. (elifesciences.org)
  • Design and Construction of Antibody Fusion Proteins Incorporating Variable New Antigen Receptor (VNAR) Domains. (bvsalud.org)
  • NK expansion and activation were stimulated by culture with artificial antigen-presenting cells (aAPCs) and IL-2, in the presence or absence of BM-MSCs. (springer.com)
  • Non-virally transformed T cells, induced to genomically integrate CAR by Sleeping Beauty transposase, were numerically expanded on artificial antigen presenting cells (aAPC) derived from K562. (bmj.com)
  • We sought to determine whether immune reactivity occurs between anti-SARS-CoV-2 protein antibodies and human tissue antigens, and whether molecular mimicry between COVID-19 viral proteins and human tissues could be the cause. (frontiersin.org)
  • We applied both human monoclonal anti-SARS-Cov-2 antibodies (spike protein, nucleoprotein) and rabbit polyclonal anti-SARS-Cov-2 antibodies (envelope protein, membrane protein) to 55 different tissue antigens. (frontiersin.org)
  • We found that SARS-CoV-2 antibodies had reactions with 28 out of 55 tissue antigens, representing a diversity of tissue groups that included barrier proteins, gastrointestinal, thyroid and neural tissues, and more. (frontiersin.org)
  • This extensive immune cross-reactivity between SARS-CoV-2 antibodies and different antigen groups may play a role in the multi-system disease process of COVID-19, influence the severity of the disease, precipitate the onset of autoimmunity in susceptible subgroups, and potentially exacerbate autoimmunity in subjects that have pre-existing autoimmune diseases. (frontiersin.org)
  • Because development of antibodies to Histoplasma can take two to six weeks, antibody tests are not as useful as antigen detection tests in diagnosing acute histoplasmosis or in immunosuppressed persons, who may not mount a strong immune response. (cdc.gov)
  • Radioimmunoassay for detecting group-specific avian RNA tumor virus antigens and antibodies. (microbiologyresearch.org)
  • If a person is exposed to blood with different antigens than his or her own, he or she may form antibodies that can result in extravascular and/or intravascular hemolysis when the recipient is reintroduced to the same antigens in a future transfusion. (medscape.com)
  • The antibody screening test performed in a clinical laboratory and/or blood bank is designed to detect the presence of unexpected antibodies, especially alloantibodies in the serum to antigens of the non-ABO blood group system: Duffy, Kell, Kidd, MNS, P, and certain Rh types that are considered clinically significant. (medscape.com)
  • Immunophenotyping relies on detecting specific antigenic determinants on the surface of WBCs by antigen-specific monoclonal antibodies that have been labeled with a fluorescent dye or fluorochrome, such as phycoerythrin (PE) or fluorescein isothiocyanate (FITC). (cdc.gov)
  • BUFFALO, NY- November 17 , 2023 - A new research paper was published in Oncoscience ( Volume 10 ) on November 10, 2023, entitled, " An immunoinformatics assessment of the cancer testis antigen, DDX53, as a potential early esophageal cancer antigen . (biotechnews.com.au)
  • Chemical complementarity of the ESCA TCR CDR3s and the cancer testis antigen DDX53 represented a disease-free survival (DFS) distinction, whereby the upper fiftieth percentile complementarity group correlated with worse DFS. (biotechnews.com.au)
  • Cancer/testis antigen MAGEC2 (also known as HCA587) is highly expressed in a wide variety of tumors and plays an active role in promoting growth and metastasis of tumor cells. (biomedcentral.com)
  • To our knowledge, this is the first time to report the role of TRIM28 in regulating the expression of cancer/testis antigen MAGEC2. (biomedcentral.com)
  • Rapid antigen tests, such as Abbott BinaxNOW ( https://www.abbott.com ) test kits, offer a less expensive and faster alternative to nucleic acid amplification tests, such as real-time reverse transcription PCR (rRT-PCR), in the diagnosis of coronavirus disease (COVID-19) ( 1 , 2 ). (cdc.gov)
  • This article provides a critical literature review and pooled analysis of diagnostic accuracy of the fully-automated Siemens SARS-CoV-2 Antigen (CoV2Ag) chemiluminescent immunoassay for diagnosis of acute SARS-CoV-2 infections. (degruyter.com)
  • The WHO also endorses that SARS-CoV-2 antigen testing, by means of laboratory-based immunoassays or rapid diagnostic tests (RDTs), may be considered a viable option - under particular circumstances - for lowering the pressure on NAAT-performing laboratories and for supporting rapid diagnosis and management of COVID-19 [ 10 ]. (degruyter.com)
  • In order to develop T cell-based assays for the diagnosis of active TB, it is imperative to identify new host markers expressed in response to established M.tb -dependent antigens, such as those used in IGRAs (ESAT-6, CFP-10, TB7.7), or novel M.tb antigens uniquely recognized by patients with active TB or LTBI. (biomedcentral.com)
  • Prostate specific antigen (PSA) is produced by the prostate gland and it is an important tumor marker in the screening and diagnosis of prostate cancer because the latter is often associated with elevated PSA levels. (scirp.org)
  • COVID-19 rapid antigen tests (RATs) have been widely used for diagnosis of COVID-19. (wikipedia.org)
  • In Sweden, there has been a steady prostate-specific antigen (PSA) velocity for the diagnosis of pros- decrease in age-standardized breast cancer mortality in women up tate cancer (15). (lu.se)
  • HspX or α-crystallin, a 16 kDa protein, is one of the dominant antigens expressed during the latent stages of M. tuberculosis infection and under various other conditions like low oxygen tension, nutrient starvation or hypoxia 7 , 8 . (nature.com)
  • Combined exposure to NQ and antigen enhanced the local expression of interleukin (IL)-4, IL-5, eotaxin, macrophage chemoattractant protein-1 and keratinocyte chemoattractant, compared with exposure to antigen or NQ alone. (ersjournals.com)
  • The aim of the present study was to elucidate the effects of NQ on airway inflammation, the local expression of cytokines such as IL-4 and IL-5 and chemokines such as eotaxin, macrophage chemoattractant protein (MCP)-1, and keratinocyte chemoattractant (KC) and Ig production related to antigen exposure. (ersjournals.com)
  • The structure of a peptide antigen corresponding to the subtype P1.7 variant of the porin PorA from the human pathogen Neisseria meningitidis was determined by solution of the X-ray crystal structure of the ternary complex of the peptide (ANGGASGQVK) in complex with a Fab fragment and a domain from streptococcal protein G to 1.95 A resolution. (rcsb.org)
  • To investigate the use of poly (lactide-co-glycolide) (PLGA) microparticles in respirable sizes as carriers for Antigen 85B (Ag85B), a secreted protein of Mycobacterium tuberculosis, with the ultimate goal of employing them in pulmonary delivery of tuberculosis vaccine. (rti.org)
  • The protein is called human leukocyte antigen B27 (HLA-B27). (medlineplus.gov)
  • The myeloperoxidase (MPO) antigen is a heme-containing protein found in the primary granules of neutrophils and monocytes. (calbiotech.com)
  • Red blood cells (RBCs) carry numerous protein and carbohydrate antigens on their surface. (medscape.com)
  • Prostate-specific antigen (PSA) is a protein produced by normal prostate cells. (medscape.com)
  • The target antigen of multiple sclerosis remains elusive. (nih.gov)
  • The aAPC were genetically modified to present the target antigen CD19 along with no co-stimulation, or co-stimulation via CD86, CD137L, or both molecules. (bmj.com)
  • We also did selective epitope mapping using BLAST and showed similarities and homology between spike, nucleoprotein, and many other SARS-CoV-2 proteins with the human tissue antigens mitochondria M2, F-actin and TPO. (frontiersin.org)
  • The current authors investigated the effects of naphthoquinone (NQ), one of the extractable chemical compounds of DEP, on antigen-related airway inflammation, local expression of cytokine proteins, and antigen-specific immunoglobulin (Ig) production in mice. (ersjournals.com)
  • Chimeric antigen receptors (CARs) are synthetic proteins expressed on the surface of T cells. (medscape.com)
  • Human leukocyte antigens (HLAs) are proteins that help the body's immune system tell the difference between its own cells and foreign, harmful substances. (medlineplus.gov)
  • Here, we describe methods to engineer antibody fusion proteins that incorporate VNARs. (bvsalud.org)
  • Here we show a method where local delivery of an antigen specific therapy can generate antigen-specific Tregs and reduce antigen-specific Th17, Th1 and autoantibodies in a collagen-induced arthritis (CIA) mouse model of RA. (aiche.org)
  • These mice were then sacrificed on day 30, and the blood, spleen and lymph nodes (LNs) were harvested to analyze the presence of antigen specific autoantibodies, T cells, and antigen specific T cells. (aiche.org)
  • In vivo studies demonstrated that the PFK15+bc2 treatment group had lower thickening of the ankle, less antigen specific autoantibodies and an increased population of proliferating Tregs. (aiche.org)
  • All others are unexpected and can be divided into alloantibodies (an antibody to an antigen that an individual lacks) and autoantibodies (an antibody to an antigen a person has). (medscape.com)
  • Pulmonary exposure to NQ dose-dependently aggravated antigen-related airway inflammation, as characterised by infiltration of eosinophils and lymphocytes around the airways and an increase in goblet cells in the bronchial epithelium. (ersjournals.com)
  • T cell-based immunotherapy, such as immune checkpoint blockade or adoptive T cell transfer, is limited by the ability of T cells to detect major histocompatibility complex (MHC)-presented antigen by tumor cells. (elifesciences.org)
  • Natural killer (NK) cell-based immunotherapy may overcome genetic mechanisms of resistance to T cell-based immunotherapy through antigen- and MHC-independent recognition of malignant cells. (elifesciences.org)
  • Antigen-specific enrichment of immunosuppressive regulatory T-cells (Tregs) and reduction of antigen-specific T-effector cells (Teff) can prevent the progression of RA. (aiche.org)
  • Notably, dendritic cells (DCs) are effective modulators of antigen-specific T-cell responses. (aiche.org)
  • Notably, the no treatment group and PFK15+bc2 treatment groups had elevated levels of antigen specific Th1 and Th17 pro-inflammatory cells compared to the prevention group, which had undetectable levels. (aiche.org)
  • To better understand the potential positive and negative impacts of T-cells in ESCA, we recovered TCR recombination reads from the TCGA-ESCA whole exome sequence (WXS) files, obtained the TCR CDR3 AA sequences, and assessed the chemical complementarity of those sequences with CTAs, as those antigens have been characterized by many approaches over decades as candidate cancer antigens. (biotechnews.com.au)
  • These microspheres containing rAg85B were assessed for their ability to deliver antigen to macrophages for subsequent processing and presentation to the specific CD4 T-hybridoma cells DB-1. (rti.org)
  • Healthy humans develop spontaneous CD8+ T cell responses to melanoma associated antigens (MA) expressed by normal melanocytes. (mdpi.com)
  • MELOE-1 and MELOE-2, two highly specific melanoma antigens involved in T cell immunosurveillance are produced by IRES-dependent translation of the long « non coding » and polycistronic RNA, meloe . (oncotarget.com)
  • In conclusion, within the MELOE family, IRES-dependent antigens represent the best T cell targets for immunotherapy of melanoma. (oncotarget.com)
  • In this respect, we have previously identified two melanoma antigens, namely MELOE-1 and MELOE-2, that were recognized by tumor-infiltrating lymphocytes (TIL) from HLA-A0201+ patients who remained relapse-free following TIL transfer in an adjuvant setting [ 3 ]. (oncotarget.com)
  • This study was done to evaluate efficacy of HBV vaccination on hepatitis B virus surface antigen (HBsAg) carrier rate in children with thalassaemia major receiving multiple blood transfusions. (who.int)
  • The surface antigen, HBsAg is a good marker in the estimation of the number of hepatitis B virus (HBV) carriers among a population because its presence shows either an acute viral hepatitis B or a chronic carriage state of the HBV [ 1 - 3 ]. (omicsonline.org)
  • Different Mycobacterium tuberculosis (M.tb) infection phase-dependent antigens may be differentially recognized in infected and diseased individuals and therefore useful as diagnostic tools for differentiating between M.tb infection states. (biomedcentral.com)
  • IGRAs are endowed with great specificity, as the antigens used are almost exclusively expressed by the Mycobacterium tuberculosis (MTB) complex, but not Mycobacterium bovis bacille Calmette-Guerin (BCG) [ 1 - 3 ]. (ersjournals.com)
  • Lambert-Niclot S , Cuffel A , Pape L , Vauloup-Fellous C , Morand-Joubert L. Evaluation of a rapid diagnostic assay for detection of SARS-CoV-2 antigen in nasopharyngeal swabs. (ajtmh.org)
  • In this study, we assessed the diagnostic potential of 118 different M.tb infection phase-dependent antigens in TB patients and household contacts (HHCs) in a high-burden setting. (biomedcentral.com)
  • The World Health Organization (WHO) COVID-19 Case Definition states that a person with a positive RAT (also known as an antigen rapid diagnostic test or Antigen-RDT) can be considered a "confirmed case of SARS-CoV-2 infection" in two ways. (wikipedia.org)
  • Following a similar strategy, we evaluated the addition of six novel peptides to the QFT antigen cocktail to improve the diagnostic performance in terms of accuracy and dynamic range of interferon (IFN)-γ level in active TB patients. (ersjournals.com)
  • The SARS-CoV-2 Antigen Rapid Diagnostic test (RDT) training package is a structured comprehensive collection of training resources and tools to enable relevant institutions to organize, run and evaluate training of trainers and/or training of health workers who will be performing SARS-CoV-2 testing using Antigen RDTs. (who.int)
  • This training does not intend to address the implementation of Antigen RDT testing across the diagnostic network. (who.int)
  • This is addressed in the SARS-CoV-2 antigen-detecting rapid diagnostic tests: An implementation guide and in policy guidance issued by the World Health Organization. (who.int)
  • Various diagnostic methods are available to identify an ongoing infection by nasopharyngeal (NPH) swab sampling. (lu.se)
  • To assess the diagnostic accuracy of point-of-care SARS-CoV-2 rapid antigen test on. (lu.se)
  • Conclusion: Our study therefore supports saliva testing as an alternative diagnostic procedure to NPH testing, and that rapid antigen test on saliva provides a potential complement to PCR test to meet increasing screening demand. (lu.se)
  • Failed T cell-based immunotherapies in the presence of genomic alterations in antigen presentations pathways may be overcome by NK cell-based immunotherapy. (elifesciences.org)
  • However, a significant number of patients are non responders to these therapies and thus, there is still room for improvement using antigen-specific immunotherapy, whether through vaccination or through T cell transfer. (oncotarget.com)
  • We investigated whether the prostate specific antigen nadir predicts prostate cancer specific and all cause mortality in men treated in a randomized trial of radiation with or without 6 months of androgen deprivation therapy. (urotoday.com)
  • The study included 204 men with cT1b-T2bN0M0 prostate adenocarcinoma and at least 1 unfavorable factor, including prostate specific antigen less than 10 to 40 ng/ml, Gleason 7 or greater, or T3 on magnetic resonance imaging. (urotoday.com)
  • We performed Fine and Gray regression, and Cox multivariable analysis to determine whether an increasing prostate specific antigen nadir was associated with prostate cancer specific and all cause mortality, adjusting for treatment, age, Adult Comorbidity Evaluation 27 score and cancer prognostic factors. (urotoday.com)
  • At a 6.9-year median followup median prostate specific antigen nadir was 0.7 ng/ml for radiation alone and 0.1 ng/ml for radiation plus androgen deprivation therapy. (urotoday.com)
  • The prostate specific antigen nadir (adjusted HR 1.18/ng/ml increase, 95% CI 1.07-1.31, p = 0.001) and Gleason 8 or greater (adjusted HR 8.05, 95% CI 1.01-64.05, p = 0.049) significantly predicted increased prostate cancer specific mortality. (urotoday.com)
  • Men who achieved a prostate specific antigen nadir of the median value or less had lower estimated prostate cancer specific and all cause mortality at 7 years (3.7% vs 18.3%, p = 0.0005 and 31.5% vs 55.0%, p = 0.002). (urotoday.com)
  • Posttreatment prostate specific antigen nadir is significantly associated with the risk of prostate cancer specific and all cause mortality after radiation with or without androgen deprivation therapy. (urotoday.com)
  • A suboptimal prostate specific antigen nadir may identify candidates for earlier intervention to prolong survival. (urotoday.com)
  • Title : Prostate-Specific Antigen Testing Initiation and Shared Decision-Making: Findings from the 2000 and 2015 National Health Interview Surveys Personal Author(s) : Li, Jun;Ding, Helen;Richards, Thomas B.;Martin, Iman;Kobrin, Sarah;Marcus, Pamela M. (cdc.gov)
  • Methods Patients with a PS 0-1, HLA-A2+ and CEA-expressing, previously-treated PC were randomized to receive 10 μg (arm A), 100 μg (arm B) or 1000 μg (arm C) of CEA peptide emulsified in Montanide and GM-CSF, given every 2 weeks until disease progression. (bmj.com)
  • Diverse repertoires of hypervariable immunoglobulin receptors (TCR and BCR) recognize antigens in the adaptive immune system. (elifesciences.org)
  • DEP enhance the antigen-specific immunoglobulin (Ig)E response 5 , 6 and aggravate airway inflammation induced by repetitive intratracheal instillation of antigen in vivo 7 - 10 . (ersjournals.com)
  • Dot-enzyme-linked immunosorbent assay (Dot-ELISA) for detection of pneumococcal polysaccharide antigens in pleural fluid effusion samples. (scielo.br)
  • Comparison with bacterial culture, counterimmunoelectrophoresis and latex agglutination Dot-enzyme-linked immunosorbent assay (Dot-ELISA) for detection of pneumococcal polysaccharide antigens in pleural fluid effusion samples. (scielo.br)
  • A dot-enzyme-linked immunosorbent assay (Dot-ELISA) for pneumococcal antigen detection was standardized in view of the need for a rapid and accurate immunodiagnosis of acute pneumococcal pneumonia. (scielo.br)
  • Pneumococcal omniserum diluted at 1:200 was employed in this assay for antigen detection. (scielo.br)
  • IGRAs, commercially available as QuantiFERON-TB Gold In-Tube test (QFT) (QIAGEN, Germantown, MD, USA) and T-SPOT.TB (Oxford Immunotec Ltd, Abingdon, UK), are based on the detection of a T-cell immune response towards RD1 antigens (ESAT-6 and CFP-10), with the addition of the TB7.7 antigen for the QFT only [ 1 ]. (ersjournals.com)
  • To improve the performance of the IGRAs, addition of MTB antigens TB7.7, Rv3425 and EsxV to the current antigen cocktail has already been attempted [ 4 , 5 ]. (ersjournals.com)
  • An electronic search was conducted in Scopus, PubMed and medRxiv using the keywords ["Siemens AND CoV2Ag"] OR ["Siemens AND SARS-CoV-2 AND antigen"] for capturing studies that investigated the accuracy of Siemens CoV2Ag for diagnosing acute SARS-CoV-2 infection against a reference SARS-CoV-2 molecular test. (degruyter.com)
  • COVID-19 rapid antigen tests or RATs, also frequently called COVID-19 lateral flow tests or LFTs, are rapid antigen tests used to detect SARS-CoV-2 infection (COVID-19). (wikipedia.org)
  • Lack of relationship between infection with avian leukosis virus and the presence of COFAL antigen in chick embryos. (microbiologyresearch.org)
  • We describe a novel device that utilizes immunosensor and bio-optical technology to detect M. tuberculosis antigen (Ag85B) in cough and demonstrate its use under field conditions during a pilot study in an area of high TB incidence. (biomedcentral.com)
  • All four antigen tests showed similar trend in detecting SARS-CoV-2 in saliva, but with variation in the ability to detect positive cases. (lu.se)
  • The rapid antigen test with the best performance could detect up to 67% of the positive cases with Ct values lower than 25, and disease duration shorter than 10 days. (lu.se)
  • The Siemens CoV2Ag fully-automated and high-throughput immunoassay approximates the minimum performance criteria for general SARS-CoV-2 antigen testing and displays excellent performance in samples with high viral load, thus representing a valuable screening solution for risk assessment in COVID-19 and for limiting viral spread. (degruyter.com)
  • Comparison of cycle threshold (Ct) values among symptomatic and asymptomatic study participants and across rapid antigen tests. (ajtmh.org)
  • Their respective clinical diagnoses are asymptomatic carrier, hepatitis B e antigen- (HBeAg-) positive hepatitis, inactive carrier, and HBeAg-negative hepatitis. (hindawi.com)
  • Second, the person with a positive Antigen-RDT could be asymptomatic but a "contact of a probable or confirmed case. (wikipedia.org)
  • Rapid antigen tests have not been sufficiently evaluated in asymptomatic patients to be used as massive population screening tools. (cun.es)
  • Head-to-head evaluation of Roche SARS-CoV-2 Rapid Antigen Test and real-time reverse transcription polymerase chain reaction (RT-PCR) as SARS-CoV-2 screening tools performed in asymptomatic adults from a semi-closed community in University of Navarra (Spain) from November 2020 to January 2021. (cun.es)
  • This study suggests that rapid antigen tests are less effective in asymptomatic population, when compared with RT-PCR. (cun.es)
  • van Buuren, M., Calis, J., Schumacher, T.N. High sensitivity of a cancer exome-based method to identify neo-antigens with CD8+ T cell immunogenic potential. (standuptocancer.org)
  • 1 Other methods include antibody tests, culture, and microscopy. (cdc.gov)
  • The tubes are then spun for 15 seconds at room temperature to facilitate antigen-antibody interaction. (medscape.com)
  • LISS is usually added to reduce clustering by Na + and Cl - ions and speed antigen-antibody attraction. (medscape.com)
  • The presence of agglutination with the addition of AHG indicates antibody binding to a specific red cell antigen. (medscape.com)
  • Chondrichthyes such as sharks and rays provide a source of single-domain antibody fragments known as variable new antigen receptors (VNARs), which have been exploited as molecular targeting agents. (bvsalud.org)
  • The major group-specific antigen (gs-a) of avian leukoviruses was detected by radioimmunoassay in extracellular medium of all embryonic cultures prepared from infected chickens. (microbiologyresearch.org)
  • Release of group-specific antigen into the extracellular medium was independent of subgroup or strain of avian leukosis or Rous sarcoma virus. (microbiologyresearch.org)
  • Knowledge of the structures of variable surface antigens such as PorA is an essential prerequisite to a molecular understanding of antigenic variation and its implications for vaccine design. (rcsb.org)
  • Blood grouping reagents : preparation and application methods / by T. C. F. Roy, G. S. Nicholson, F. A. Ala. (who.int)
  • The Abbott BinaxNOW rapid antigen test is cheaper and faster than real-time reverse transcription PCR (rRT-PCR) for detecting severe acute respiratory syndrome coronavirus 2. (cdc.gov)
  • Discover 115 products from Rapid Antigen Test Kit manufacturers, suppliers, distributors, and dealers across India. (tradeindia.com)
  • Rapid Antigen Test Kit product price in India ranges from 20 to 1,00,000.0 INR and minimum order requirements from 1 to 1,00,000. (tradeindia.com)
  • Whether you're looking for Coviself Covid 19 Rapid Antigen Test For Self Test Kit, Rapid Antigen Test Kit Covid, Covid-19 Antigen Rapid Test Kit etc, you can explore and find the best products from Tradeindia. (tradeindia.com)
  • We offer a wide range of Rapid Antigen Test Kit selections in various locations including Delhi, Jaipur, Mumbai, Pune, Chennai and many more. (tradeindia.com)
  • Further studies are needed to evaluate different options to improve screenings based on rapid antigen test, such as the use of clinical questionnaires to select higher risk-participants, the confirmation of negative results with RT-PCR or the use of repetitive sequential testing. (cun.es)
  • The HBs antigen screening was made by the 4th generation, 'sandwich' type of ELISA test. (omicsonline.org)
  • The Flowflex™ COVID-19 Antigen Home Test is all you need to determine your family's Covid-19 status, whether symptoms are present or not. (dailysale.com)
  • With column (gel) agglutination (see Methods ), the procedure varies by the type of test to be carried out (typing or screening). (medscape.com)
  • Objectives: In this study, we aimed to determine if the detection of SARS-CoV-2 can be performed alternatively on saliva specimens by rapid antigen test. (lu.se)
  • To assure the accuracy and reliability of CD4+ T-lymphocyte test results obtained within individual laboratories and to assure the comparability of results between laboratories, standard methods for performing the test, as well as guidelines for quality control and quality assurance, are desirable. (cdc.gov)
  • Un test d'amplification en chaîne par polymérase (PCR) multiplex a également été mis au point pour identifier les isolats, et il s'est avéré que cette autre solution constituait un test diagnostique rapide, sensible et précis. (who.int)
  • Treponema pallidum is suitable for ELISA and Western blots, excellent antigen for detection of T. Pallidum with minimal specificity problems. (prospecbio.com)
  • Sensitivity, specificity and predictive values were calculated using RT-PCR as reference method. (cun.es)
  • Using accurate and easy to use rapid antigen detection tests (RADTs) to identify group A beta-haemolytic Streptococci (GABHS) sore throat infections could reduce unnecessary antibiotic prescribing and antimicrobial resistance. (soton.ac.uk)
  • These workplaces might benefit from effective rapid antigen tests that enable employers to quickly identify persons infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) for isolation and to guide contact tracing, thereby reducing workplace transmission. (cdc.gov)
  • however, the median Ct values were significantly higher in individuals with false-negative rapid antigen tests. (ajtmh.org)
  • The radioimmunoassay of the group-specific antigen seems to be well suited to complement the COFAL (complement fixation avian leukosis) and RIF (resistance inducing factor) tests in the detection of leukosis virus in infected material. (microbiologyresearch.org)
  • Pneumococcal omniserum proved to be an optimal polyvalent antiserum for the detection of pneumococcal antigen by Dot-ELISA. (scielo.br)
  • T-cell receptors (TCR) and B-cell receptors (BCR) are hypervariable immunoglobulins that play a key role in recognizing antigens in the vertebrate immune system. (elifesciences.org)
  • cryp tococcal antigen (CrAg) can be detected in blood several weeks to months (22 days on average) before the onset of signs and symptoms of men ingitis (6, 7) and therefore, can be used as a trigger for pre-emptive antifungal therapy in HIV-infected individuals with low CD4 cell counts. (researchsquare.com)
  • The immune non-activating metabolite-based MPs modulate DC function and subsequently alter antigen specific T cell immune responses in mice. (aiche.org)
  • Overall, these data are consistent with the possibility that TCR-antigen interaction induces selective pressure that results in antigen loss, a process referred to as immuno-editing [ 16 - 18 ], and, eventually, tumor cell escape from an anti-tumor immune response. (biotechnews.com.au)
  • Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) has been recently identified as a heterophilic ligand for Tim-3. (medscimonit.com)
  • In this respect, the choice of the targeted antigens remains a critical issue [ 2 ] and the ideal antigen(s) should have the following characteristics : be as tumor specific as possible and stimulate a broad T cell repertoire in the majority of patients (i.e. generate many epitopes in various HLA contexts). (oncotarget.com)
  • Localization of avian tumor virus group-specific antigen in cell and virus. (microbiologyresearch.org)
  • Cell reports methods. (lu.se)
  • The presence or absence of these antigens in an individual is important, because they determine the type of blood that should be given in case a blood transfusion is necessary. (medscape.com)
  • Current RA therapies do not target the root cause of RA or address the antigen specific immune responses against synovial tissue. (aiche.org)
  • Histoplasma antigen detection in urine and/or serum is the most widely used and most sensitive method for diagnosing disseminated histoplasmosis and acute pulmonary histoplasmosis following exposure to a large inoculum. (cdc.gov)
  • Des enfants souffrant de thalassémie majeure, âgés de moins de 60 mois, ayant reçu plus de 24 transfusions sanguines et qui étaient négatifs pour l'antigène de surface du virus de l'hépatite B au moment de la première transfusion ont été inclus dans une étude de cohorte réalisée dans un hôpital de Bahawalpur (Pakistan) en 2009 et 2010. (who.int)
  • AP2S1 , P3H4 , and RAC3 were identified as candidate tumor-specific antigens, and patients with the BCS2 and BCS1A subtypes were identified as candidate populations for mRNA vaccines. (frontiersin.org)
  • Antigens were evaluated using the 7-day whole blood culture technique in 23 pulmonary TB patients and in 19 to 21 HHCs (total n = 101), who were recruited from a high-TB incidence community in Cape Town, South Africa. (biomedcentral.com)
  • The objective of this study was to document the prevalence of HBs antigen among youth aged 15 to 24 in Togo in 2010 and its associated factors. (omicsonline.org)
  • Method: This was a cross sectional study, conducted in 2010. (omicsonline.org)
  • In this study soil samples were analysed from endemic regions of the country, and B. anthracis isolates were identified by classical bacteriological and biochemical methods. (who.int)
  • We hypothesize that blocking DC glycolysis and simultaneous antigen expression may lead to the generation of tolerogenic DCs (tDCs) and subsequent antigen specific Treg induction. (aiche.org)
  • AP2S1 , P3H4 , and RAC3 were identified as candidate tumor-specific antigens for BLCA. (frontiersin.org)
  • Also, NQ exhibited adjuvant activity for the antigen-specific production of IgG 1 and IgG 2a . (ersjournals.com)
  • More recently, it has also been demonstrated that PQ aggravates antigen-related airway inflammation in mice, and that PQ also has adjuvant activity for antigen-specific Igs 25 . (ersjournals.com)
  • Additionally, the PFK15+bc2 prevention group had an increased population of antigen specific Tregs and number of proliferating Tregs in the popliteal LNs. (aiche.org)
  • The N-terminal amino acid of an avian leukosis group-specific antigen from avian myeloblastosis virus. (microbiologyresearch.org)
  • Identification and localization of avian leukosis group-specific antigen within 'leukosis-free' chick embryos. (microbiologyresearch.org)
  • Multiple group specific antigen components of avian tumor viruses detected with chicken and hamster sera. (microbiologyresearch.org)
  • Origin of group-specific antigen of chicken leukosis viruses. (microbiologyresearch.org)
  • Immunofluorescent studies of group-specific antigen of the avian sarcoma-leukosis viruses. (microbiologyresearch.org)
  • To ensure the RADTs were evaluated objectively, a standardized in vitro method using known concentrations of GABHS was used to remove the inherent biases associated with clinical studies. (soton.ac.uk)