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  • Electroporation
  • Another treatment method is the utilisation of electricity as the membrane-permeabilizing agent (electroporation or electrotransformation). (wikipedia.org)
  • These specific genetic engineering techniques include various recombinant DNA and RNA methods such as micro-injection, electroporation, micro-encapsulation, liposome fusion, protoplast fusion or other "hybridization techniques that overcome natural physiological, reproductive or recombination barriers, where the donor cells or protoplasts do not fall within the same taxonomic family, in a way that does not occur by natural multiplication or natural recombination. (wikipedia.org)
  • comprises
  • 4. The method for producing a liposome of claim 2, wherein the water-miscible organic solvent comprises one or more organic solvents selected from t-butanol, 1-propanol, 2-propanol, and 2-butoxyethanol. (patentsencyclopedia.com)
  • 4. The method for producing the lipid-based cochleate according to claim 1 , wherein the cochleate comprises a biologically relevant molecule. (google.com.au)
  • 6. The method according to claim 1 , wherein the washing step comprises centrifuging the two-phase polymer system to separate the cochleate precipitate, removing the supernatant containing the polymer, resuspending the precipitate in a washing buffer, centrifuging the washed precipitate, and optionally repeating the resuspension and centrifugation steps one or more times. (google.com.au)
  • 21. The method of claim 13 , wherein said delivery system comprises at least one of cholesterol and phospolipids. (google.com)
  • 3. The method of claim 1, wherein the pancreatic β cell specific targeting moiety comprises an antibody or an aptamer. (freepatentsonline.com)
  • 4. The method of claim 1, wherein the pancreatic β cell specific targeting moiety comprises a moiety selected from the group consisting of glucagon-like peptide-1 (GLP-1), glucagon-like peptide-2 (GLP-2), peptide YY (PYY), neuropeptide Y (NPY), pancreatic peptide (PP), exendin-4, naphthylalanine and naphthylalanine derivatives. (freepatentsonline.com)
  • 5. The method of claim 1, wherein the inhibitor comprises an apoCIII inhibitor. (freepatentsonline.com)
  • 7. The method of claim 1, wherein the method comprises administering the composition to a subject that overexpresses apoCIII relative to control. (freepatentsonline.com)
  • nanoparticle
  • To be able to develop effective methods for large scale production and to meet the regulatory requirements for eventual clinical implementation of nanocarriers, one needs to have in-depth knowledge of the principles of nanoparticle preparation. (ac.ir)
  • Along with delivery and transport methods, there are several means of functionalizing, or activating, the nanoparticle carriers. (wikipedia.org)
  • One type of nanoparticle involves use of liposomes as drug molecule carriers. (wikipedia.org)
  • particle size
  • SIOS could detect plasma opsonization of liposomes by demonstrating a increase in particle size a nd a lso changes in the particle translocation rate. (izon.com)
  • biocompatible
  • Liposomes are composed of vesicular bilayers, lamellae, made of biocompatible and biodegradable lipids such as sphingomyelin, phosphatidylcholine, and glycerophospholipids. (wikipedia.org)
  • form
  • Although radium does not easily form stable molecular complexes, there has been presented data on methods to increase and customize its specificity for particular cancers by linking it to monoclonal antibodies, by enclosing the 223Ra in liposomes bearing the antibodies on their surface. (wikipedia.org)
  • Fusion
  • Liposome Fusion/ModulationPeptide-Induced Fusion of LiposomesEve-Isabelle Pécheur and Dick HoekstraLiposomes: Applications in Protein-Lipid Interaction Studies,Sujoy Ghosh and Robert BellLipids in Viral FusionAnu Puri, Maite Paternostre, and Robert BlumenthalPart III. (indigo.ca)
  • sequential
  • The best method for terminal sterile filtration is the sequential filtration of a dispersion of liposomes through a 0.45 and 0.22 um filtration system, and liposomes larger than 0.2 um, or aggregation of smaller liposomes will obstruct and clog this filter system as well as the ultrafiltration system employed to remove unentrapped components. (google.com)