• We retrospectively studied maternal and neonatal variables of 73 term and near-term infants and 30 preterm infants, born over a period of 10.5 years and exhibiting early-onset neonatal sepsis (positive blood cultures in the first 72 hours of life). (ima.org.il)
  • Predominant pathogens in term and near-term infants were gram-positive compared with gram-negative organisms (mostly Escherichia coli ) in preterm infants. (ima.org.il)
  • Early-onset neonatal sepsis in term infants differs in bacterial species from that in preterm infants, with predominantly gram-positive organisms in term and near-term infants and gram-negative organisms in preterms. (ima.org.il)
  • We've heard a lot about delayed umbilical cord clamping in preterm infants over the last several years. (medela.us)
  • McAdams asked why this was not a standard of care for preterm infants in particular, and Tarnow-Mordi et al warn that more evidence is needed before implementation. (medela.us)
  • Many trials have now been performed in preterm infants and demonstrated advantages to delayed cord clamping, such as a need for fewer transfusions, prevention of iron deficiency into childhood, reductions in necrotizing enterocolitis, intraventricular hemorrhage and late onset sepsis. (medela.us)
  • 3 Cord milking has sometimes been the preferred method for basically getting more blood to the preterm infant in less time. (medela.us)
  • Objectives: To evaluate the benefits and harms of stem cell-based interventions for prevention or treatment of GM-IVH and EoP in preterm infants. (lu.se)
  • for treatment studies, we included preterm infants (less than 37 weeks' gestation), of any postnatal age, with ultrasound diagnosis of GM-IVH or with EoP. (lu.se)
  • in one, intracerebroventricular injection of MSCs will be administered to preterm infants up to 34 weeks' gestational age. (lu.se)
  • Notably, autologous cord blood mononuclear cells (ACBMNCs) can substantially prevent severe BPD and decrease the inflammatory response in surviving very preterm neonates. (spandidos-publications.com)
  • Subsequently, the association between cord blood Angptl7 levels and BPD incidence in a cohort of very preterm neonates was assessed (cohort 2). (spandidos-publications.com)
  • Our previous study demonstrated that autologous cord blood mononuclear cells (ACBMNCs), which are rich in stem cells, could substantially prevent moderate or severe BPD in surviving very preterm neonates, and that the immunomodulatory effect of MNCs contributed in mitigating the severity of BPD ( 13 ). (spandidos-publications.com)
  • do preterm babies benefit from receiving breathing support before the cord is clamped? (cochrane.org)
  • allowing preterm infants to receive blood from the placenta after birth and before clamping the umbilical cord has health benefits for the baby and is not harmful for the mother. (cochrane.org)
  • After clamping the cord, most preterm babies are given some form of breathing support like continuous positive airway pressure (CPAP). (cochrane.org)
  • Preterm infants born before 32 weeks' gestation (32 weeks from the first day of the woman's last period (menstruation) to the current date) who had clamping of the umbilical cord delayed for 60 seconds after birth were selected at random to enter a group of babies who received breathing support and a group of babies who did not receive breathing support. (cochrane.org)
  • Placental transfusion (by means of delayed cord clamping (DCC), cord milking, or cord stripping) confers benefits for preterm infants. (cochrane.org)
  • It is not known if providing respiratory support to preterm infants before cord clamping improves outcomes. (cochrane.org)
  • To assess the efficacy and safety of respiratory support provided during DCC compared with no respiratory support during placental transfusion (in the form of DCC, milking, or stripping) in preterm infants immediately after delivery. (cochrane.org)
  • Randomized, cluster randomized, or quasi-randomized controlled trials enrolling preterm infants undergoing DCC, where one of the groups received respiratory support before cord clamping and the control group received no respiratory support before cord clamping. (cochrane.org)
  • In this study, 150 preterm infants of less than 32 weeks' gestation undergoing 60 second DCC were randomized to a group who received respiratory support in the form of continuous positive airway pressure (CPAP) or positive pressure ventilation during DCC and a group that did not receive respiratory support during the procedure. (cochrane.org)
  • one in every 70 babies (1.4%) is born before 32 weeks (very preterm), yet these births account for over half of infant deaths. (biomedcentral.com)
  • The Cochrane Review suggests that deferring umbilical cord clamping for preterm births may improve outcome, but larger studies reporting substantive outcomes and with long-term follow-up are needed. (biomedcentral.com)
  • Studies of the physiology of placental transfusion suggest that flow in the umbilical cord at very preterm birth may continue for several minutes. (biomedcentral.com)
  • In the UK, infant mortality (deaths in the first year of life) for babies born very preterm (before 32 weeks gestation) is 144/1000 live births, compared to 1.8/1000 for those born at term (38 to 41 weeks) [ 1 ]. (biomedcentral.com)
  • Creatine kinase (CK), lactate dehydrogenase (LDH), and amylase levels of preterm infants following long-term tocolysis in pregnant women are limited. (hindawi.com)
  • This study included 215 preterm infants born to women treated with and without ritodrine hydrochloride. (hindawi.com)
  • Although ritodrine hydrochloride crosses the placenta freely [ 6 ], the data concerning escape enzyme, such as CK, lactate dehydrogenase (LDH), and amylase levels of preterm infants following long-term ritodrine tocolysis in pregnant women are limited. (hindawi.com)
  • Therefore, the aim of this study is to determine if the tocolytic therapy affects CK, LDH, and amylase levels in the umbilical blood of preterm infants. (hindawi.com)
  • To examine the clinical significance of the relationship between ritodrine hydrochloride and escape enzymes in the preterm infants, we reviewed all patients who were delivered at less than 36 weeks of gestation with preterm birth in the Perinatal Center of Social Insurance Funabashi Central Hospital between July 1, 2005, and June 30, 2008. (hindawi.com)
  • It was previously known that monocytes isolated from preterm cord blood show suppressed responses to innate immune activation. (ubc.ca)
  • Beyond the immediate postnatal period, preterm infants remain particularly vulnerable to respiratory viral infections. (ubc.ca)
  • Overall, my study suggests that most high-risk preterm infants develop antibody responses against RSV by one year of age, in the absence of overt clinical signs. (ubc.ca)
  • This challenges the dogma that preterm infants are unable to fight respiratory illnesses without getting sick and provide insights into the highest period of vulnerability to these viruses. (ubc.ca)
  • The overall goal of my PhD was to investigate the immune system of premature infants during the neonatal period.In chapter 2, I examined the whole blood response to immune stimulation of two prototypic Toll-like receptors: TLR4 and TLR7/8, in preterm infants aged 1-42 days in the neonatal intensive care unit. (ubc.ca)
  • These findings support previous observations made from preterm cord blood studies. (ubc.ca)
  • Specifically, preterm infants should receive large quantities of vitamin K prophylaxis, infant formula and breast milk fortifiers as these neonates cannot easily produce vitamin K or have lowest amount of vitamin K [ 8 ]. (biomedcentral.com)
  • Methods: In the INTERBIO-21st Newborn Case-Control Study, a major component of Phase II, our objective is to investigate the mechanisms potentially responsible for preterm birth and small for gestational age and their interactions, using deep phenotyping of clinical, growth and epidemiological data and associated nutritional, biochemical, omic and histological profiles. (ox.ac.uk)
  • This retrospective study recruited 82 preterm infants (gestational age 28-36 weeks) diagnosed with NRDS as the NRDS group, and 82 non-NRDS preterm infants as the control group, respectively. (biomedcentral.com)
  • Enzyme linked immunosorbent assay (ELISA) was performed to evaluate the 25(OH)D 3 level in the serum of the cord blood in preterm neonates. (biomedcentral.com)
  • Cord blood 25(OH)D 3 levels were significantly lower in NRDS preterm infants than control group infants. (biomedcentral.com)
  • 25(OH)D 3 levels in cord blood can be used to predict NRDS in preterm infants. (biomedcentral.com)
  • In addition, 25(OH)D 3 levels in cord blood were positively correlated with Apgar score (1 min/5 min) and negatively correlated with oxygen support/CPAP duration in preterm infants with NRDS. (biomedcentral.com)
  • 25(OH)D 3 level is an independent risk factor for NRDS in preterm infants. (biomedcentral.com)
  • Neonatal respiratory distress syndrome (NRDS) is a common respiratory disease among preterm infants [ 1 ]. (biomedcentral.com)
  • Although the endotracheal pulmonary surfactant therapy has improved patient outcomes [ 3 ], NRDS remains a serious disease with high mortality among preterm infants. (biomedcentral.com)
  • Vitamin D is thought to play a crucial role in embryonic development, cell growth and differentiation, including lung development and fetal lung maturation, while vitamin D deficiency may aggravate neonatal lung disease in preterm infants [ 8 ]. (biomedcentral.com)
  • The retrospective study was performed to investigate the relationship between respiratory distress syndrome of preterm infants and umbilical cord serum vitamin D level. (biomedcentral.com)
  • Eighty-two children with NRDS were selected for the study group and 82 preterm infants without NRDS were selected as the control group. (biomedcentral.com)
  • GAUK 1322119 - Detection of placental microvesicles in the cord blood of preterm infants, 2019 - 2021 , K. Pekárková / J. Soukup. (prionlab.cz)
  • This complication occurs in about 15% of infants and is more widespread in postterm neonates. (hindawi.com)
  • We hypothesized that maternal antibodies may help protect neonates and young infants from severe diseases related to HPeV3. (cdc.gov)
  • Such data might help determine why severe diseases related to HPeV3 develop in some neonates and young infants. (cdc.gov)
  • We measured NATs to HPeVs in cord blood from newborns and in serum samples from neonates and young infants with diseases related to HPeV3 infection who were admitted to hospitals in Niigata, Japan. (cdc.gov)
  • We also measured NATs in intravenous immunoglobulin (IVIG) preparations sold in Japan to determine if IVIG could be a potential treatment for HPeV3-related diseases in neonates and young infants. (cdc.gov)
  • To determine the incidence, type of pathogens and resistance to antibiotics among newborns with early-onset neonatal sepsis, and to identify the risk factors predisposing infants to resistant pathogens in order to reevaluate antibiotic regimens appropriate for resistant bacteria in these high risk neonates. (ima.org.il)
  • Umbilical cord blood acid-base alterations are related to subsequent adverse outcome events for neonates. (who.int)
  • We collected cord blood from neonates and venous blood from mothers at delivery. (ox.ac.uk)
  • 5% of infants born through MSAF develop meconium aspiration syndrome (MAS) which is a real threat to many newborns worldwide, with a case fatality rate of 5% (as much as 40%), in addition to MAS short- and long-term pulmonary and neurodevelopmental sequelae which could occur [ 5 , 6 ]. (hindawi.com)
  • Untargeted liquid chromatography-mass spectrometry metabolomic profiles were measured in cord blood from 399 newborns from four European cohorts (ENVIRONAGE, Rhea, INMA and Piccolipiu). (nature.com)
  • 0.9 kU·L −1 (all at-risk infants available) were recruited as cases and 815 infants, who were simultaneously selected at random from the remaining newborns, participated as infants at random risk. (ersjournals.com)
  • Methods In this prospective, observational study, we included term newborns delivered by elective C/S. Babies were segregated into two groups as early (within 15 seconds) and late cord clamping (at 60th seconds). (bmj.com)
  • I am a clinician-scientist and developmental immunologist at BC Children's Hospital, UBC (Vancouver, Canada) that conducts discovery research focused mainly on the developing human immune system of newborns and young infants. (ubc.ca)
  • This includes any research directions that have the potential to translate into therapeutics or improve the health of newborns and young infants. (ubc.ca)
  • In both veterinary and human perinatology, analyzing blood gases and metabolites has emerged as an important tool for evaluating newborns [ 13 ] [ 31 ] , but reports on dogs are scarce. (encyclopedia.pub)
  • Public cord blood banks, like any normal blood cell, collect cord blood of newborns with the consent of the parents, keep it in process and provide this cord blood to anyone, if necessary, after some other procedures. (myhealthandbeautyguide.com)
  • Timing of delayed cord clamping varies: from 30 seconds to 120 seconds, others until the cord stops pulsating (particularly in term infants), and still others study the milking of the cord rather than delayed clamping. (medela.us)
  • Polycythemia and resulting hyperbilirubinemia is the concern that has been raised for delayed cord clamping in term infants. (medela.us)
  • Boere et al studied flow through the umbilical cord of healthy term infants following delivery. (medela.us)
  • 6 They found no significant effect on infant position and placental transfusion in term infants. (medela.us)
  • A total of 400 singleton term infants delivered by vaginal delivery or caesarean section were studied at a hospital in Kerman, Islamic Republic of Iran, in 2001. (who.int)
  • The BiHIVE1 cohort was recruited in Cork, Ireland (7500 live births per annum), this study included full-term infants with PA enrolled at birth. (ucc.ie)
  • Early-onset neonatal sepsis is a major cause of morbidity and mortality among newborn infants. (ima.org.il)
  • Both obstetricians and the neonatal team have a hard time waiting even 30 seconds to clamp the cord in a blue, limp infant. (medela.us)
  • This often leads to increased neonatal blood volume at birth and may allow longer for transition to the neonatal circulation. (biomedcentral.com)
  • For births with cord clamping after at least two minutes, initial neonatal care is at the bedside. (biomedcentral.com)
  • The mean volume of placental transfusion for term births is 100 ml, which is around 29 ml/kg birth weight and 36% of neonatal blood volume at birth [ 11 ]. (biomedcentral.com)
  • Umbilical cord blood is readily accessible to study the premature neonate's immune system, but it does not capture important maturation events that may occur during the neonatal period. (ubc.ca)
  • ABSTRACT A prospective cross-sectional study was carried out to determine the relationship and predic- tive value of umbilical cord blood pH for adverse neonatal outcomes. (who.int)
  • Neonatal respiratory distress syndrome (NRDS) is a critical disease in premature infants. (biomedcentral.com)
  • Methods HIV-infected pregnant women receiving 600 mg efavirenz once daily had intensive steady-state 24-h pharmacokinetics profiles during the second trimester (2T), third trimester (3T) and 6-12 weeks postpartum (PP). Maternal and umbilical cord blood samples were drawn at delivery and neonatal washout pharmacokinetics were determined. (penta-id.org)
  • Methods: Pregnant mothers were enrolled in a birth cohort in Bangladesh between 2008 and 2011, and children were followed at birth and age 20-40 months. (cdc.gov)
  • 18 ] analysed the metabolome in cord blood plasma from 26 cases and 26 controls differing in their postnatal weight trajectories using targeted mass spectrometry (MS) analysis of 415 metabolites, nested in an American cohort. (nature.com)
  • Methods: A prospective cohort of 92 chronic HBV-infected mother-and-child pairs recruited over three years was analyzed. (nus.edu.sg)
  • From a cohort of 19 live birth infants, we collected cord blood and placenta samples to evaluate for signs of acute and chronic histologic inflammation and cell phenotype characterization. (figshare.com)
  • We analyzed a second cohort of stillborn infants with and without chorioamnionitis to classify and enumerate cell infiltrate phenotypes in the spleen, thymus, and lung. (figshare.com)
  • In cohort 2, the cord blood Angptl7 levels were significantly lower in infants who later developed BPD. (spandidos-publications.com)
  • METHODS: Contacts in a cohort study at 10 United States sites received both IGRAs (QuantiFERON-TB Gold In-Tube (QFT-GIT) and T-SPOT.TB (T-SPOT)) and TST. (cdc.gov)
  • The transfer and decay of maternal antibodies against enterovirus A71, and dynamics of antibodies due to later natural infections in Chinese infants: a longitudinal, paired mother-neonate cohort study. (ox.ac.uk)
  • METHODS:We did a longitudinal cohort study with mother-neonate pairs in local hospitals in southern China during 2013-18. (ox.ac.uk)
  • Materials and methods: This study comprised mother-infant pairs from the Programming Research in Obesity, Growth, Environment and Social Stressors (PROGRESS) study, a prospective birth-cohort that enrolled 1050 pregnant women from Mexico City who were receiving prenatal care between December 2007 and July 2011. (mssm.edu)
  • Methods: This thesis utilised three distinct, well-defined cohorts throughout, the BiHIVE1 cohort (2009- 2011), the BiHiVE2 cohort (2012-1015), and the BASELINE longitudinal birth cohort (2008- 2016). (ucc.ie)
  • The BiHiVE2 validation cohort was recruited in Cork, Ireland and Karolinska Huddinge, Sweden (4400 live births per annum), this study included infants with PA along with healthy control infants. (ucc.ie)
  • This study examined the influence of maternal fish consumption during pregnancy on umbilical cord mercury (Hg) concentrations in a multiethnic cohort of women in Hawaii. (biomedcentral.com)
  • The US Zika Pregnancy Registry collects data to monitor pregnancy and infant outcomes in pregnancies with laboratory evidence of possible Zika virus infection. (cdc.gov)
  • Information on infant birth outcomes and cord blood (for measurement of IgE) will be collected at the time of delivery. (biomedcentral.com)
  • The increasing number of CDs has led to scrutiny of the impact that type of delivery has on infant health and predisposition to disease outcomes. (biomedcentral.com)
  • This study examined whether maternal and/or fetal folate status in pregnancy is associated with infant allergic outcomes. (edu.au)
  • Folate status determined by both food frequency questionnaires and folate levels in maternal and cord blood serum was examined in relation to infant allergic outcomes at 1 year of age (n=484). (edu.au)
  • Although neutralizing antibody titers (NATs) have been reported as lower for mothers of infants with HPeV3 infection than for mothers of infants with other viral infections ( 16 ), little is known about patients infected with HPeV3 ( 15 ). (cdc.gov)
  • Mothers of infants with antibiotic-resistant organisms were more likely to have prolonged rupture of membranes and prolonged hospitalization before delivery and to be treated with antibiotics. (ima.org.il)
  • Rates of bacterial resistance to the combination of ampicillin and gen tami cin, though higher among infants born to mothers with prolonged hospitalization who had been treated with antibiotics, still remained very low in our department. (ima.org.il)
  • Nine mothers and 7 infants were included in the analysis. (nih.gov)
  • Median concentrations in the infants were 33% and 25% of their mothers', measured in cord blood, and infant plasma, respectively. (nih.gov)
  • We aimed to determine the correlation between maternal serum and umbilical cord blood HBV DNA levels in infants delivered by chronic HBV-infected mothers and to describe the effect of cord blood viremia on vertical transmission. (nus.edu.sg)
  • HBeAg +ve mothers were younger with higher HBV and cord viremia. (nus.edu.sg)
  • Infants delivered by HBeAg positive mothers and mothers with high HBV DNA of more than 6 LOG IU/mL (1 x 106 IU/mL) have increased relative risk of cord blood viremia. (nus.edu.sg)
  • Conclusions: Maternal HBV DNA and presence of HBeAg were positively correlated to cord blood HBV DNA in infants delivered by chronic HBV-infected mothers. (nus.edu.sg)
  • Pregnant mothers, from enrollment at 27 weeks gestation to birth, and then their infants, from birth to age 6 months, were assigned to receive placebo or one of two dosages of daily of oral vitamin D3. (vitamindwiki.com)
  • Methods Serum 25-hydroxyvitamin D [25(OH)D] level was measured of the mothers before delivery and of the infants both at birth (cord blood) and at six months of age. (erdogan.edu.tr)
  • D (25-OHD) concentrations were low in mothers and infants. (who.int)
  • The EPA agreed and established a reference dose of 5.8 μg/L MeHg in blood in their recommendations to limit exposures of pregnant and nursing mothers and young children [ 12 ]. (biomedcentral.com)
  • Human parechovirus type 3 (HPeV3) is an emerging pathogen that causes sepsis and meningoencephalitis in young infants. (cdc.gov)
  • Our findings indicate that maternal antibodies to HPeV3 may help protect young infants from severe diseases related to HPeV3 and that antibody supplementation may benefit these patients. (cdc.gov)
  • Very young infants are dependent solely on maternal antibodies and lack the ability to mount a cell-mediated response ( 4 ). (cdc.gov)
  • Sertraline plasma concentrations were measured around pregnancy weeks 21 and 30, at delivery, 1-month postpartum, in cord blood and at 48 h of age in the infant. (nih.gov)
  • During pregnancy the formation of alloreactive anti-human leukocyte antigen (HLA) antibodies are a major cause of acute rejection in organ transplantation and of adverse effects in blood transfusion. (frontiersin.org)
  • Alloreactive anti-human leukocyte antigen (HLA) antibodies formed during pregnancy are a major cause of acute rejection in organ transplantation and of adverse effects in blood transfusion, such as febrile non-hemolytic transfusion reactions, immunological platelet refractoriness or transfusion-related acute lung injury (TRALI) ( 1 , 2 ). (frontiersin.org)
  • At the conclusion of today's session, the participant will be able to: understand the latest estimates for birth defects associated with Zika virus infection during pregnancy,discuss additional considerations for evaluating and managing infants with possible congenital Zika virus infection, and apply the updated recommendations outlined in the additional considerations for the evaluation and management of infants with possible congenital Zika virus infection. (cdc.gov)
  • Pregnant women in the United States with laboratory evidence of possible Zika virus infection regardless of whether or not they have symptoms, and their exposed infants are included in the US Zika Pregnancy Registry. (cdc.gov)
  • Vaccination of women with Tdap during pregnancy is expected to provide some protection to infants from pertussis until they are old enough to be vaccinated themselves. (cdc.gov)
  • These findings indicate that maternal antibodies from women immunized before pregnancy waned quickly and the concentration of maternal antibodies was unlikely to be high enough to provide passive protection to infants ( 4 ). (cdc.gov)
  • Also placenta or "fruit cake") is an all female higher mammals ( Eutheria ), including the people and some marsupials ( Metatheria ) during gestation (or pregnancy ) evolving fabric of the wall of the uterus , which belongs to the embryonic organism, is formed by it and is interwoven with blood vessels from the mother and the embryo. (zxc.wiki)
  • Arterial with the following inclusion criteria: single- blood gases and blood cord pH are useful ton pregnancy, no underlying disease and for measuring the degree of asphyxia and gestational age of 38-42 weeks. (who.int)
  • We sought to assess the association of Pb exposure during pregnancy with mitochondrial DNA (mtDNA) content, a sensitive marker of mitochondrial function, in cord blood. (mssm.edu)
  • A blood test and an ultrasound test during the first trimester of pregnancy. (nih.gov)
  • A blood test during the second trimester of pregnancy. (nih.gov)
  • This work aimed to clarify the interaction between the fetus and pregnant patients with gestational diabetes mellitus (GDM), the lipid metabolomics analysis of the fetal umbilical cord blood of GDM patients and normal pregnant women were performed to screen out the specific lipid metabolites for pathogenesis of GDM. (techscience.com)
  • PIH was diagnosed where there was systolic blood pressure higher than 140 mm Hg and/or diastolic blood pressure higher than 90 mm Hg after 20 gestational weeks. (hindawi.com)
  • Our purpose was to study the variability in the plasma concentrations in pregnant women and the passage to their infants. (nih.gov)
  • Data have been used to estimate the number of fetuses and infants with birth defects potentially related to Zika, provide information on the phenotype of congenital Zika syndrome, and plan for services for pregnant women, their infants, and families affected by Zika to ensure infants are linked to care. (cdc.gov)
  • In October 2011, in an effort to reduce the burden of pertussis in infants, the Advisory Committee on Immunization Practices (ACIP) recommended that unvaccinated pregnant women receive a dose of tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis vaccine (Tdap) ( 1 ). (cdc.gov)
  • Tdap given to pregnant women will stimulate the development of maternal antipertussis antibodies, which will pass through the placenta, likely providing the newborn with protection against pertussis in early life, and will protect the mother from pertussis around the time of delivery, making her less likely to become infected and transmit pertussis to her infant ( 1 ). (cdc.gov)
  • These updated recommendations on use of Tdap in pregnant women aim to optimize strategies for preventing pertussis morbidity and mortality in infants. (cdc.gov)
  • Asymptomatic increases in blood creatine kinase (CK) and amylase have been reported in pregnant women treated with tocolytic agents [ 2 - 5 ]. (hindawi.com)
  • Objectives To determine the prevalence and risk factors of vitamin D deficiency in pregnant women and their infants at birth (cord blood) and at six months of age in Turkey, as well as to assess the compliance rates of families with vitamin D supplementation. (erdogan.edu.tr)
  • Results The study included a total of 140 pregnant women and their infants. (erdogan.edu.tr)
  • Conclusions In Turkey, vitamin D deficiency still exists in both pregnant women and infants. (erdogan.edu.tr)
  • In 1961 Saling teamed up with K. Damaschke to develop a high-speed approach to testing for perinatal blood-oxygen levels and foetal blood analysis. (wikipedia.org)
  • Whether these adverse perinatal mental states (and their associated dysregulated stress responses) contribute to the development of allergic disease in infants is under active, prospective investigation. (biomedcentral.com)
  • A better understanding of the effects of perinatal factors on susceptibility to allergic disease in the infant can lead to development of interventions when plasticity in physiologic development is still relatively abundant [ 3 ]. (biomedcentral.com)
  • Infants with perinatal asphyxia had matched inclusion criteria across both BiHiVE1 and BiHiVE2. (ucc.ie)
  • Maternal blood serum was screened for HLA class I and II antibodies, identification of Donor Specific Antibody (DSA), activation of complement measured by C1q and IgG4 concentrations. (frontiersin.org)
  • One study evaluated persistence of maternal antipertussis antibody concentrations from maternal delivery and cord blood pairs from women who received Tdap within the prior 2 years ( 4 ). (cdc.gov)
  • The estimated antipertussis antibody concentrations at birth in most of these infants were considered unlikely to provide adequate protection. (cdc.gov)
  • Lead concentrations in both maternal blood (2nd and 3rd trimester and at delivery day) and in cord blood were measured by ICP-MS. Multivariable regression models adjusting for multiple confounders were fitted with 410 mother-infant pairs for whom complete data for mtDNA content, lead levels, and covariates were available. (mssm.edu)
  • Women reporting consumption exceeding 12 ounces fish per week were significantly more likely to have cord blood Hg levels of 5 μg/L or more, but mean Hg concentrations were not significantly higher (6.1 ± 3.3 v 5.0 ± 3.7). (biomedcentral.com)
  • Further, almost half of study participants had cord blood Hg concentrations at or exceeding 5 μg/L. (biomedcentral.com)
  • Congenital cytomegalovirus (C-CMV) infection affects 0.4-2% of newborn infants in Israel, most of whom are asymptomatic. (ima.org.il)
  • 7 at 1 minute, meconium-stained amniotic fluid and fetal distress were significant risk factors for acidaemia in newborn infants. (who.int)
  • Two additional infants, who had not been screened, were detected after clinical suspicion. (ima.org.il)
  • The clinical course of the infants was followed. (nih.gov)
  • Infant atopy (assessed via skin-prick testing and clinical history) will be assessed at 1 year of age, along with information on the infant's health and stress response (salivary cortisol). (biomedcentral.com)
  • If there truly is no effect of infant position on amount of placental transfusion, this may make both the delivery in term, healthy infants and infants who need resuscitation prior to cord clamping easier. (medela.us)
  • Placental transfusion is the transfer of blood between the placenta and the baby at birth. (biomedcentral.com)
  • This study aimed to investigate the correlation between the serum 25(OH)D 3 level in the cord blood of premature infants and the prognosis of NRDS. (biomedcentral.com)
  • Therefore, exploring the risk factors of NRDS in premature infants is of great value for the prevention, diagnosis and treatment of NRDS. (biomedcentral.com)
  • Randomization was to mART versus infant NVP (iNVP) prophylaxis. (bvsalud.org)
  • As a result, infants are predisposed to develop bleeding disease unless the can get adequate vitamin K prophylaxis during childbirth [ 4 , 5 ]. (biomedcentral.com)
  • We discovered that approximately half of the tests with increased IgE levels in the umbilical blood were due to IgE from the mother," Dr. Klaus Bønnelykke, PhD says. (scienceblog.com)
  • A low pH (less than 7.04 to 7.10) means there are higher levels of acids in the baby's blood. (medlineplus.gov)
  • The objective of this study was to determine if the tocolytic therapy affects CK, LDH, and amylase levels in the umbilical blood. (hindawi.com)
  • CK, LDH, and amylase levels in the umbilical blood at delivery were determined. (hindawi.com)
  • Determinants of impaired lung function in the group of current wheezers were: time in years since first wheeze, a parental history of atopy, current sensitisation to indoor allergens, elevated cord blood IgE levels and a low ponderal index at birth. (ersjournals.com)
  • Conclusions In our study we found that rSO 2 brain measurements and FTOE values were higher in the late cord clamping group without the need for any therapy as a result of high bilirubin and hematocrit levels. (bmj.com)
  • I identified major functional deficits in pro-inflammatory cytokine levels compared to term cord blood, which were not due to a lack of immune cells. (ubc.ca)
  • Infants who received and did not take regular vitamin D supplements were compared in terms of 25(OH) levels. (erdogan.edu.tr)
  • Maternal age, maternal education level, and the number of siblings were determined to be determining factors on infants' 25(OH)D levels at six months (p (erdogan.edu.tr)
  • Serum 25(OH)D levels of infants should be tested periodically and personalized vitamin D supplementation planning is required based on test results. (erdogan.edu.tr)
  • Emergency CD infants have higher hormone levels than those born via elective CD, but lower than those born via VD [ 9 ]. (biomedcentral.com)
  • Identifying physio-metabolic alterations in the blood from the umbilical vein to evaluate the concentration of gases, glucose, lactate, calcium, hematocrit levels, and blood pH of newborn puppies will make it possible to determine the risk of complications due to intrauterine asphyxia. (encyclopedia.pub)
  • Infants who developed allergic disease (namely eczema) did not show any differences in cord blood or maternal folate levels compared with children without disease. (edu.au)
  • umbilical cord blood and infant liver reserve levels of vitamin K are substantially below adult levels. (biomedcentral.com)
  • Blood will be collected to study the function of the genes that control sex hormone levels in each person. (cdc.gov)
  • Umbilical cord blood Hg levels were 5 μg/L or more in 44% of women. (biomedcentral.com)
  • Based primarily on cord blood levels found in the Faroe Islands study [ 10 ], the Environmental Protection Agency (EPA) and the National Research Council (NRC) determined a benchmark dose lower limit (BMDL), or the lowest dose expected to be associated with a small increase in the incidence of adverse outcome, of 58 μg/L (ppb) MeHg in cord blood [ 11 ]. (biomedcentral.com)
  • Generally, HPeV1 and HPeV6 cause mild gastroenteritis and respiratory infections in infants and children ( 2 , 7 ). (cdc.gov)
  • In Chapter 4, I studied infants at high-risk for respiratory syncytial virus (RSV) infections. (ubc.ca)
  • The umbilical cord is the cord connecting the baby to the mother's womb. (medlineplus.gov)
  • Infants could be placed higher for resuscitation or on the mother's abdomen for bonding while the cord is still attached. (medela.us)
  • A blood test enables a health care provider to check for "markers," such as certain proteins, in the mother's blood that suggest an increased likelihood of Down syndrome. (nih.gov)
  • As in the first trimester, a blood test enables a health care provider to check for markers in the mother's blood. (nih.gov)
  • In addition, theories linking exposure to substances in the womb (through the mother's blood) with diseases found in adulthood has also been accepted by a number of scientists from different fields. (cdc.gov)
  • ALDACTAZIDE is effective in significantly lowering the systolic and diastolic blood pressure in many patients with essential hypertension, even when aldosterone secretion is within normal limits. (nih.gov)
  • In this study, we have investigated the cord blood metabolic signatures of rapid growth in infancy and overweight in early childhood in four European birth cohorts. (nature.com)
  • Some parents may choose to save (bank) their child's cord blood for this and other future medical purposes. (medlineplus.gov)
  • Cord blood and blood samples from the child are used to assess whether the child's genes and epigenetic changes influence allergic-disease susceptibility. (biomedcentral.com)
  • The recovery rate is important because you want to pick a bank that will not only securely store your child's cord blood, but will do so with the highest safety and preservation standards. (myhealthandbeautyguide.com)
  • To test the hypothesis that maternal antibodies can protect this population, we measured neutralizing antibody titers (NATs) to HPeV3 and other genotypes (HPeV1 and HPeV6) in 175 cord blood samples in Japan. (cdc.gov)
  • Maternal blood samples and umbilical cord samples were collected at delivery. (frontiersin.org)
  • Serum 25-hydroxyvitamin D (25(0H)D) concentration was measured at enrollment, 36 weeks gestation, on cord blood samples, and at 2,4 and 6 months of age. (vitamindwiki.com)
  • We followed up and collected blood samples from the children at ages 2, 4, 6, 12, 24, and 36 months and tested for the presence of neutralising antibodies against EV-A71 with virus neutralisation assays. (ox.ac.uk)
  • Protein expression measurements were conducted with sandwich enzyme-linked immunosorbent assays (ELISA) on cord serum samples. (ucc.ie)
  • CBR operates out of an 80,000-square-foot laboratory in Tuscon, Arizona, and has stored more than 875,000 cord blood and tissue samples to date. (myhealthandbeautyguide.com)
  • More precise and comparable data about the risk of poliomyelitis could be obtained in future surveys by incorporating a standard case definition, by using house- to- house case- finding methods in representative community- based samples, by analyzing and presenting rates in more clearly defined ways, and by selecting stable populations for study. (who.int)
  • Although CRS has been estimated to occur among 20%-25% or more of infants born to women who acquire rubella during the first trimester, the actual risk of infection and subsequent defects may be considerably higher. (cdc.gov)
  • Umbilical cord serum, plasma and whole blood were processed and biobanked across all cohorts at delivery and stored at -80°C. Techniques employed throughout the thesis include blood processing, RNA isolations of whole blood miRNA and mRNA, and subsequent cDNA synthesis and quantitative real-time polymerase chain reaction (qPCR). (ucc.ie)
  • The National Child and Adolescent Health Policy of May 2009 sets out a goal for MOPH of reducing infant and under 5 mortality further to less than 100,000 deaths per year by the year 2013. (who.int)
  • Child Health Committee to meet twice a year to review our progress and direct further action for achievement of this goal of further infant and under 5 mortality reduction by 2013. (who.int)
  • The enrolled woman/infant pairs were randomised to: placebo/placebo, 1000IU/400IU, or 2000IU/800IU. (vitamindwiki.com)
  • The target sample size is 100 to 110 mother-infant pairs recruited over 12 months at eight sites. (biomedcentral.com)
  • METHODS: The multicomponent, open-label strategy PROMISE trial enrolled breastfeeding mother-infant pairs not meeting in-country criteria for maternal ART (mART) initiation in the postpartum component within 5 days of delivery. (bvsalud.org)
  • However, researchers from COPSAC (Copenhagen Studies on Asthma in Childhood) at the Faculty of Health Sciences, University of Copenhagen recently discovered indications that IgE in the blood of the umbilical cord could originate from the mother, and decided to conduct a focused study on this. (scienceblog.com)
  • In a study published June 9 by the journal Stem Cell Reports , and funded by the National Heart, Lung, and Blood Institute, the multi-institutional research team reports on the comprehensive characterization of a large set of induced pluripotent stem cells (iPSCs). (neurosciencenews.com)
  • An early study by Yao & Lind led to recommendations that infants should not be held more than 20 cm above or below the introitus. (medela.us)
  • Color Doppler ultrasonography (CDU) with grayscale imaging and special attention to the spermatic cord is the study of choice to evaluate patients with acute scrotal pain due to its widespread availability and its ability to diagnose testicular torsion with a high degree of sensitivity and specificity and to distinguish other causes of scrotal pain and swelling. (medscape.com)
  • Most of the study infants (83%) were delivered by caesarean section. (cochrane.org)
  • the single study included in the review did not provide sufficient evidence either for or against the use of breathing support before cord clamping. (cochrane.org)
  • The results from one study with wide CIs for magnitude of effect do not provide evidence either for or against the use of respiratory support before clamping the umbilical cord. (cochrane.org)
  • The present study will examine whether prenatal perceived stress and/or physiologic maternal stress responses are associated with the development of allergies in infants, in a diverse group of immigrant women. (biomedcentral.com)
  • A detailed description of study subjects and methods is provided elsewhere 15 . (ersjournals.com)
  • Background and aims The aim of our study is to compare the postnatal cerebral tissue oxygenation values in babies with early versus late cord clamping born after elective C/S. (bmj.com)
  • To the best of our knowledge, we were the first at the time to study functional TLR responses during this critical development period.In chapter 3, I used RNA-sequencing methods to investigate how these responses are developmentally regulated. (ubc.ca)
  • We audited the primary care records of enrolled infants to a median age of 18 months, identified all acute visits and determined whether oral antibiotics were prescribed at each visit. (vitamindwiki.com)
  • Among 23 infants with washout data available, median (interquartile range) elimination half-life was 65.6 h (40.6-129). (penta-id.org)
  • The age, BMI, delivery methods, and infant weight were different between GDM and control. (techscience.com)
  • The discrepancy between studies may be due to screening differences, both in method sensitivity and the sampling time after delivery, as HLA antibodies may persist or become gradually undetectable over time ( 1 - 5 ). (frontiersin.org)
  • One reason for this could be that the umbilical cord was compressed during labor or delivery. (medlineplus.gov)
  • The newborn will be watched for hypoglycemia (low blood sugar) after delivery. (medlineplus.gov)
  • You can also decide to bank or donate cord blood at the time of your delivery. (medlineplus.gov)
  • Immediately after the delivery of the fe- of umbilical cord blood pH range from tus, the umbilical cord was clamped at a 7.25-7.28 [ 7 ]. (who.int)
  • Type of delivery was not associated with global methylation in our population, even after adjustment for maternal age, maternal smoking, and infant gender. (biomedcentral.com)
  • however, the stress encountered by infants varies vastly between delivery types. (biomedcentral.com)
  • After delivery, umbilical cord blood and a dietary survey were obtained. (biomedcentral.com)
  • The 'gold standard' method to assess humoral antibody responses fol owing vaccination is the neutralization assay. (who.int)
  • This translates to meaning we have reduced the annual number of infant and under 5 deaths from approximately 300,000 per year to 200,000. (who.int)
  • Teratomas, benign tumors containing the developing cells of different body parts, allowed researchers to see if the iPSCs could form the body's three basic germ cell lines - endoderm (gut region), ectoderm (epidermis, nerve tissue, etc.) and mesoderm (muscles, blood cells, etc. (neurosciencenews.com)
  • Being pluripotent means iPSCs can generate cells from each of the three basic germ cell lines that form the body - endoderm (gut region), ectoderm (epidermis, nerve tissue, etc.) and mesoderm (muscles, blood cells, etc. (neurosciencenews.com)
  • Acute Bacterial Meningitis Acute bacterial meningitis is rapidly developing inflammation of the layers of tissue that cover the brain and spinal cord (meninges) and of the fluid-filled space between the meninges (subarachnoid. (msdmanuals.com)
  • The prevalence of vitamin D deficiency was 87.1% in infants at birth but decreased to 5.8% at sixth month. (erdogan.edu.tr)
  • 65.7% of infants received vitamin D supplements regularly. (erdogan.edu.tr)
  • Despite regular vitamin D use, it was determined that 2.2% of the infants in the supplementation compliant group had vitamin D deficiency. (erdogan.edu.tr)
  • After vitamin D enters the blood circulation, it undergoes two hydroxylation actions in the liver and kidneys to form 25(OH)D 3 and 1,25-dihydroxy vitamin D 3 (1,25-(OH) 2 D 3 ), respectively [ 6 ]. (biomedcentral.com)
  • Using recently developed statistical approaches that estimate mediation and interaction effects simultaneously, we evaluated whether the association between cord blood manganese and cognitive score was mediated through anthropometric measures at birth. (cdc.gov)
  • We also found evidence of mediated interaction (both mediation and interaction, β =-0.03, SE = 0.01, p = 0.01) with birth length in the association between cord blood manganese and cognitive score. (cdc.gov)
  • The researchers subsequently determined how much IgE originated from the mother by using hypersensitive analyses of IgE in the blood of the umbilical cord, blood from the mother, and blood from the baby six months after birth. (scienceblog.com)
  • Right after the birth of your baby, the umbilical cord is clamped and cut. (medlineplus.gov)
  • Most hospitals routinely collect cord blood for testing at birth. (medlineplus.gov)
  • 3 Even though cord clamping was performed as late as 5 minutes after birth on average with a range up to just over 10 minutes, pulsations continued in some of the cords. (medela.us)
  • The breathing support was given after birth of the baby and before the cord was clamped. (cochrane.org)
  • In such a situation, it was reasonable to think that at the time of birth, the cord blood ie the blood of the umbilical cord and the cells in it, should be collected and stored somewhere and used as per the requirement in the future. (myhealthandbeautyguide.com)
  • He was involved in a number of "firsts", among which the most frequently cited occurred in 1960 when he used blood gas analyses to assess the effectiveness of resuscitation procedures in respect of new-born infants. (wikipedia.org)
  • Results: miRNA Panel: One-hundred and sixty infants had miRNA qPCR analyses across both BiHiVE1 and BiHiVE2. (ucc.ie)
  • Predicted mRNA Targets: One-hundred and twenty-six infants had mRNA analyses. (ucc.ie)
  • results: Geometric mean cord blood MeHg was 0.94 g/L (95% CI: 0.84, 1.07). (cdc.gov)
  • miR-374a-5p was decreased in infants diagnosed as having HIE compared with healthy control infants (P = 0.009), miR-376c-3p was decreased in infants with PA compared with healthy control infants (P = 0.004), and miR-181b-5p was decreased in infants eligible for therapeutic hypothermia (TH) (P = 0.02). (ucc.ie)
  • In future, if we want to use blood from the umbilical cord for to assess the risk of an infant developing asthma or allergy we need to take the transfer of IgE from the mother into account. (scienceblog.com)
  • This pilot trial aims to assess the feasibility of conducting a large randomised trial comparing immediate and deferred cord clamping in the UK. (biomedcentral.com)
  • We aimed to assess the dynamics of maternal EV-A71 antibodies to inform choice of potential vaccination strategies to protect infants younger than 6 months, because they have a substantial burden of disease. (ox.ac.uk)
  • Does perceived stress in pregnant immigrant women predispose their infants to allergic disease development? (biomedcentral.com)
  • Cord blood/maternal plasma concentration ratio (range) was 0.67 (0.36-0.95). (penta-id.org)
  • To reduce this burden, optimizing the current vaccination program and protecting infants who are at highest risk for death are immediate priorities. (cdc.gov)
  • the quality of evidence was low, mainly because more infants need to be studied for definite conclusions. (cochrane.org)
  • All 24 infants were further investigated, and 3 (12.5%) had central nervous system involvement (including hearing impairment) and were offered intravenous ganciclovir for 6 weeks. (ima.org.il)
  • To retrospectively analyze the results of a screening program for C-CMV performed at the Sheba Medical Center, Tel Hashomer, during a 1 year period, using real-time polymerase chain reaction (rt-PCR) from umbilical cord blood. (ima.org.il)
  • This may explain why many studies have showed poor results from the use of umbilical cord IgE. (scienceblog.com)
  • During the first trimester, this combined method results in more effective or comparable detection rates than methods used during the second trimester. (nih.gov)
  • PUBS is the most accurate diagnostic method and can confirm the results of CVS or amniocentesis. (nih.gov)