Chemicals and Drugs
BenzothiazolesThiazolesCytochrome P-450 CYP1A1Antineoplastic Agents
DerivativesSynthesis of BenzothiazolesBenzoxazoleAnilineDerivativeAbstractBenzoxazolesHeterocyclic compoundCompounds of the seriesBenzeneAnalyticalAntibacterial and antifungalRiluzoleReactionSelectiveSpatial resolutionHandbookDeterminationYieldsEstimationBiologicalDiseasesOrganicQuantitativeActivityChemicalsEfficientSimpleExperimentalWaterMetabolitesEvaluateCharacteristicsOriginallyPractical methodSensitivityAgentsSubstancePureTreatmentTotalConvenientRESEARCHMaleStudyProductsSuccessfulDetermine
Derivatives5
  • Although the parent compound, benzothiazole is not widely used, many of its derivatives are found in commercial products or in nature. (wikipedia.org)
  • A series of novel 2- substituted benzothiazole dithiomidocarbonate derivatives were synthesized by the reaction of 2-amino benzothiazole with various halides. (ijpsr.com)
  • One such prominent heterocyclic system is benzothiazole with several of its derivatives exhibiting diversified biological activity. (ijpsr.com)
  • Activity of 2-alkylthio-6-aminobenzothiazoles and their 6-N-substituted derivatives (3-(2-alkylthio-6-benzothiazolylaminomethyl)-2-benzothiazolinethiones and 3-(2-alkylthio-6-benzothiazolylaminomethyl)-6-bromo-2-benzothiazolinones) concerning photosynthesis inhibition in algae Chlorella vulgaris and in spinach chloroplasts has been correlated with lipophilicity and dipole moments of the effecters using the Hansch method. (chemicalpapers.com)
  • A convenient and efficient synthesis of 2-substituted benzothiazole derivatives are carried out by the one-pot reaction of 2-aminothiophenol with various aromatic aldehydes in using Bi2O3 nanoparticles as a catalyst at 60°C. The structure of the synthesized compounds have been confirmed on the basis of by FT-IR, H1 NMR, C13 NMR, Mass spectrometry and elemental analysis. (ajnanomat.com)
Synthesis of Benzothiazoles1
  • Zhi-Bing Dong describes an iodobenzene-promoted palladium-catalyzed synthesis of benzothiazoles via intramolecular coupling. (thieme.de)
Benzoxazole2
  • Part 1: Post Complexation Cross-Coupling Reactions A straight forward method for post-complexation derivatizations of diastereomerically pure bis-cyclometalated benzoxazole and benzothiazole iridium(III) complexes was developed. (uni-marburg.de)
  • Moreover, just 2 mol% of Cu2+@GO-PABA could catalyze the C-H activation reaction of benzoxazole and benzothiazole with secondary amines in >94% yields. (sharif.edu)
Aniline2
  • The tetra(ethylene glycol) derivative of benzothiazole aniline, BTA-EG 4 , is a novel amyloid-binding small molecule that can penetrate the blood-brain barrier and protect cells from Aβ-induced toxicity. (jneurosci.org)
  • Members of the benzothiazole aniline (BTA) family of compounds are characterized as a class of small molecules that have shown great promise in preventing Aβ-protein interactions. (jneurosci.org)
Derivative2
  • Firefly luciferin can be considered a derivative of benzothiazole. (wikipedia.org)
  • A benzothiazole derivative is suggested as a dye for arsenic detection. (wikipedia.org)
Abstract1
  • Contact Nguyen Duc Vuong, e-mail address: [email protected] 77 SIMULTANEOUS SPECTROPHOTOMETRIC DETERMINATION OF Cu(II), Co(II), Ni(II) USING 1-(2-PYRIDYLAZO)-2- NAPHTHOL (PAN) BY CHEMOMETRIC METHOD Nguyen Duc Vuong1, Nguyen Duc Minh1 and Nguyen Xuan Tong2 1Faculty of Chemistry, Quang Binh University 2 University of Industry, Ho Chi Minh City Abstract. (timtailieu.vn)
Benzoxazoles1
  • The aim of this work is to synthesize, characterize and evaluate the biological activity of a series of quinoline linked benzimidazoles (5a-c), benzothiazole (6a-c) and benzoxazoles (7a-c) bearing azetidin-2-one / thiazolidin-4-one / tetrazole nuclei. (upt.ro)
Heterocyclic compound2
  • Benzothiazole is an aromatic heterocyclic compound with the chemical formula C 7H 5NS. (wikipedia.org)
  • 1-8 Benzothiazole is one of the most important heterocyclic compound, weak base, having varied biological activity they are widely found in bioorganic and medicinal chemistry with application in drug discovery. (ijpsr.com)
Compounds of the series1
  • Quinoline linked benzimidazoles and benzothiazoles with thiazolidin-4-one nucleus has shown good antibacterial and antifungal activity than other compounds of the series. (upt.ro)
Benzene4
  • Benzothiazoles consist of a 5-membered 1,3-thiazole ring fused to a benzene ring. (wikipedia.org)
  • Benzothiazoles are related to thiazoles, which lack the fused benzene ring. (wikipedia.org)
  • Benzothiazole consists of a 5-membered 1,3thiazole ring fused to a benzene ring. (ijpsr.com)
  • The benzene and the thiazole rings of 2-alkylthio-6-R-benzothiazoles are the electron-donor part of the investigated benzothiazole effecters. (chemicalpapers.com)
Analytical4
  • Analytical Methods. (wikipedia.org)
  • NIOSH manual of analytical methods (NMAM) fourth edition. (cdc.gov)
  • The manual is a collection of air, biological, bioaerosol, and bulk analytical methods that NIOSH has evaluated. (cdc.gov)
  • Residue groups requiring analytical methods. (miguel-osorio.com)
Antibacterial and antifungal1
  • The test compounds were screened for their antimicrobial activity (antibacterial and antifungal) by disc diffusion method and the results of the microbial activity indicates that the test compounds exhibited varying degree of antimicrobial activity. (ijpsr.com)
Riluzole1
  • Among the drugs proposed is riluzole (2-amino-6-trifluoromethoxy benzothiazole), which was originally developed as an anticonvulsant [ 29 ] but has been used in a number of trials for psychiatric conditions in which glutamate excess has been proposed as part of the pathologic mechanism [ 30 - 33 ]. (hindawi.com)
Reaction1
  • 3. Each reaction was monitored by TLC by using appropriate solvent system, which was selected by trial and error method. (ijpsr.com)
Selective1
  • In particular, radical cross-coupling reactions exploiting SmI 2 -induced selective generation of aminoketyl radicals have emerged as concise and efficient methods for constructing 2-azabicycles, pyrrolidines and complex polycyclic barbiturates. (mdpi.com)
Spatial resolution1
  • Commercial small animal PET scanners use different methods to achieve desirable levels of sensitivity and spatial resolution. (sharif.edu)
Handbook1
  • Handbook of Chemical Property Estimation Methods. (charite.de)
Determination3
  • The aim of this work was to develop methods of identification, determination of impurities and quantitative determination of N- (5-ethyl- [1,3,4] -thiadiazole-2-yl)-2-nitrobenzamide for further application in standardization of the substance. (uran.ua)
  • The optimal conditions for the determination of the impurities by the method of thin-layer chromatography using the method of internal normalization are selected. (uran.ua)
  • The findings suggest that the traditional method of using matched untreated controls as a reference developed from historic solvent-based treatments for determination anti-swelling efficacy (ASE) may underestimate the a. (irg-wp.com)
Yields1
  • 2-Arylthiobenzothiazoles were readily prepared in good yields by the S-arylation of benzothiazole-2-thiol with diaryliodonium salts at room-temperature in the ionic liquid, 1-butyl-3-methylimidazolium tetrafluoroborate ([bmim]BF 4 ). (aston.ac.uk)
Estimation2
  • The Henry's Law constant for benzothiazole is estimated as 3.7 X 10-7 atm-cu m/mole(SRC) using a fragment constant estimation method(1). (charite.de)
  • When using higher book french animation history use methods, such as % vat, research couple or detector sets a research, as the valuable enlevages will almost find with the linear Estimation. (drpulley.co.uk)
Biological2
  • Benzothiazole moieties are part of compounds showing numerous biological activities such as antimicrobial, anticancer, antihelminthic, anti-diabetic activities etc. (ijpsr.com)
  • Our physics remain found by biological( Culture Survey, Organizational Analytics) and strong methods( minutes, formula of borate electropherograms, P regimes). (drpulley.co.uk)
Diseases1
  • The second patent claimed methods of treating diseases, including Parkinson, using benzothiazole compounds. (chisum.com)
Organic3
  • The journal endeavors to broaden the knowledge case for organic chemistry both through reports of fundamental new chemistry and the improvement and the expansion of existing methods including, for example, their application in new areas or a significant extension of the substrate scope. (thieme.de)
  • In this study, the results of water repellency testing using a digital swellometer method for water-borne organic-preservative systems with water repellent additives are reported. (irg-wp.com)
  • The sampling modules passively collected organic chemical compounds on an adsorbent sampling medium, which was later analyzed by a gas chromatograph using a modified EPA Method 8260/8270. (cdc.gov)
Quantitative1
  • The mask fit test was performed using the quantitative method specified in the Japanese Industrial Standard T8150:2021. (bvsalud.org)
Activity1
  • Methods associated with preparation and use of such compounds, pharmaceutical compositions comprising such compounds and methods to modulate the activity of G12C mutant KRAS protein for treatment of disorders, such as cancer, are also provided. (justia.com)
Chemicals1
  • Data from a reliable in vivo test conducted before the enforcement of Commission Regulation (EU) 640/2012 of 06 July 2012 amending, for the purpose of its adaptation to technical progress, Regulation (EC) No 440/2008 laying down test methods pursuant to Regulation (EC) No 1907/2006 of the European Parliament and of the Council on the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH) are available. (europa.eu)
Efficient1
  • We have accomplished an efficient, convenient, and inexpensive and diversity oriented method for the synthesis ofbenzothiazole-quinazolinobenzodiazepine hybrid derivaties.The structures of all the newly synthesized molecules were assigned by elemental analysis and spectral data. (derpharmachemica.com)
Simple2
  • This paper presents a new simple method to evaluate wood and wood products for their resistance to swelling and to assess wood preservatives for their ability to dimensionally stabilize treated wood exposed to water. (irg-wp.com)
  • Herein, a simple dipping method to insert octadecyltrichlorosilane (OTS) into cell walls and to deposit the self-assembled hydrophobic monolayers (SAMs) of OTS is reported. (irg-wp.com)
Experimental1
  • The Koc of benzothiazole is estimated as approximately 295(SRC), using an experimental log Kow of 2.01(1,SRC) and a regression-derived equation(2,SRC). (charite.de)
Water1
Metabolites1
  • Furthermore, the castration method only exhibited a negligible effect on metabolites and volatile aroma compounds in the cooked meat. (animbiosci.org)
Evaluate1
  • This study was conducted to evaluate the effect castration method (half- and complete-castration) on meat yield and quality characteristics of Hanwoo male cattle. (animbiosci.org)
Characteristics1
  • The physical-chemical properties and spectral characteristics of N-(5-ethyl-[1,3,4]-thiadiazole-2-yl)-2-nitrobenzamide were studied, and chemical identification methods were proposed. (uran.ua)
Originally1
  • N30 (N-(4-nitrophenyl methyl) benzothiazole-6-amine, Fig. 1a ) was originally provided by Professor Zhuorong Li at the Institute of Medicinal Bioechnology Chinese Academy of Medical Sciences, Beijing, China. (biomedcentral.com)
Practical method1
  • A practical method to prepare Cu2+supported onpara-aminobenzoic acid grafted on GO was reported. (sharif.edu)
Sensitivity2
  • These methods are intended to promote accuracy, sensitivity, and specificity in industrial hygiene analyses. (cdc.gov)
  • Background: The two dialkylthiocarbamyl benzothiazole sulphides, dimethyl-thiocarbamylbenzothiazole sulphide (DMTBS) and diethylthio-carbamylbenzothiazole sulphide (DETBS) were shown to be good markers of both thiuram and mercaptobenzothiazole sensitivity. (lu.se)
Agents2
  • Various benzothiazoles such as 2-substituted benzothiazole received much attention due to unique structure and its uses as radioactive amyloidal imaging agents, and anticancer agents. (ijpsr.com)
  • This method can also be used to determine breakdown products of these preservative agents, which protect leather from microbiological attack. (iso.org)
Substance2
  • Provided is a method for producing a 2-alkylcarbonylnaphtho[2,3-b]furan-4,9-dione-related substance, which is suitable for the production on an industrial scale. (justia.com)
  • To determine the concomitant impurities in the substance, the TLC method is recommended. (uran.ua)
Pure1
  • Chromatographically pure sample of N- (5-ethyl- [1,3,4] -thiadiazole-2-yl) -2-nitrobenzamide, methods of IR, UV and 1H NMR spectroscopy. (uran.ua)
Treatment1
  • Benzothiazoles are prepared by treatment of 2-mercaptoaniline with acid chlorides: C6H4(NH2)SH + RC(O)Cl → C6H4(NH)SCR + HCl + H2O Benzothiazole occurs naturally in some foods but is also used as a food additive. (wikipedia.org)
Total1
  • METHODS: A total of 94 male welders were recruited. (bvsalud.org)
Convenient1
  • A convenient method for C-S cross-coupling of aryl bromides with various thiols involves the use of a 1,1′-bis(diphenylphosphino)ferrocene (DPPF)-ligated palladium complex with N,N -diisopropylethylamine (DIPEA) as the base. (organic-chemistry.org)
RESEARCH1
  • Methods: A qualitative, exploratory, descriptive research design was employed to conduct psychosocial and health screenings of children and their families. (bvsalud.org)
Male1
  • METHODS: The study enrolled 100 male e-waste workers and 51 all-male non-e-waste workers or controls. (bvsalud.org)
Study1
  • This study aimed to determine the pattern of antibiotic prescriptions in the Paediatrics department of Rivers State University Teaching Hospital, Port Harcourt.Method:A point prevalence survey was conducted in the Paediatric wards and Special Care Baby Unit (SCBU) on 13 November 2021. (bvsalud.org)
Products1
  • This protocol afforded advantages i.e. purification of products by non-chromatographic method. (ajnanomat.com)
Successful2
  • The formation of triazolyl-modified ME-resins was proven by LC-ESI-TOF methods, indicating the successful covalent modification of the amino resin with the azides 1-4. (limkinase-signal.com)
  • The use of microlenses seems to be the most successful method to obtain autostereoscopic vision. (unican.es)
Determine1
  • This method has been applied to determine Cu(II), Co(II) and Ni(II) in laboratorial samples. (timtailieu.vn)