• https://github.com/fritzsedlazeck/Sniffles ) that provide unprecedented sensitivity and precision for variant detection, even in repeat-rich regions and for complex nested events that can have substantial effects on human health. (nature.com)
  • Space weather forecasts can potentially benefit from the higher sensitivity provided by this novel method. (iac.es)
  • When both DSE and Thallium-201 are performed in the same patient, discordant results are often obtained In fact, in comparative studies where both techniques have been used prior to revascularisation procedures, the sensitivity, specificity and predictive value for the detection of viable myocardium have been found to differ. (escardio.org)
  • Some limitations of HRP colorimetric detection systems are decreased sensitivity when compared to AP colorimetric detection systems, fading of blots upon exposure to light, inhibition of HRP activity by azide, and nonspecific color precipitation. (bio-rad.com)
  • Colorimetric detection is considered a medium-sensitivity method when compared to radioactive or chemiluminescence detection. (bio-rad.com)
  • The existing detection methods for this disease have numerous shortcomings, including low sensitivity, time consuming procedures, and high contamination vulnerability. (medscimonit.com)
  • Conclusions: Data from this study showed that single-step PCR has a low sensitivity and thus, it is not a suitable alternative for accurate detection of P. knowlesi. (duke.edu)
  • The purpose of this work was to establish the sensitivity of the speck-based method for detecting the froth bed parameters to the binarization threshold. (rudmet.ru)
  • With the goal of improving sensitivity and accommodate various application settings, we developed a multiplex-PCR-based method comprised of 172 pairs of specific primers, and demonstrated its efficiency to detect SARS-CoV-2 at low copy numbers. (biorxiv.org)
  • On the basis of wavelet transformation algorithms for the detection of features and estimation of their parameters were developed. (scirp.org)
  • The mathematical algorithms behind the detection depend on understanding the details of the interaction of magnetic fields, radar pulses, and vibrating components within the landmine as well as with the properties of various soil and clutter objects. (soldiersystems.net)
  • Advancing university physical models and analysis continue to support the improvement of the detection algorithms. (soldiersystems.net)
  • As a result, specific methods for removing frames with low illumination and algorithms for determining the threshold binarization values for different types of flotation machines are proposed. (rudmet.ru)
  • In fluorescence detection ( C ), the antibody is labeled with a fluorophore. (bio-rad.com)
  • Secondary antibodies conjugated to fluorophores are gaining popularity and can be directly visualized and captured with a compatible imager, without the need for additional liquid substrate (see Fluorescence Detection ). (bio-rad.com)
  • The purpose of this paper was to do a literature review and to compare the methods of caries detection, based on radiographic methods, laser fluorescence and electric chain. (bvsalud.org)
  • Single-molecule long-read sequencing has the potential to dramatically advance the field, although high error rates are a challenge with existing methods. (nature.com)
  • For Lexington, Massachusetts-based Quanterix, which to date has deployed assays for protein analysis on its Single Molecule Array, or Simoa, platform, the approach demonstrates the applicability of its technology in nucleic acid detection, and miRNA detection in particular, as it prepares to launch a new system. (genomeweb.com)
  • It's very disruptive from our view because if we can do direct detection with single-molecule resolution, this opens up option of doing microRNAs, which is the obvious choice," said Diaz Mochon. (genomeweb.com)
  • As detailed in the new paper, by pairing the Destina chemistry with Quanterix's platform, the investigators were able to develop a single-probe method for detecting miRNA from human serum using Quanterix's single-molecule arrays, which had the advantages of reading sequence specificity down to a single base without the need for amplification. (genomeweb.com)
  • 2013). 'Detection of cathepsin D in ewe's milk by Western Blotting method', Mljekarstvo , 63(1), str. (srce.hr)
  • Dolenčić Špehar I, Martinković F, Havranek J, Marinculić A, Tudor Kalit M, Kalit S. Detection of cathepsin D in ewe's milk by Western Blotting method. (srce.hr)
  • This paper shows the presence of cathepsin D and its forms in ewe's milk by modified Western Blotting method. (srce.hr)
  • The theory behind several commonly used western blotting detection methods such as colorimetric, chemiluminescent and fluorescent methods, and other less common methods, such as chemifluorescence, autoradiography, and immunogold labeling methods are highlighted below. (bio-rad.com)
  • Early diagnosis of SARS-CoV infection, which involves viral detection, is important for preventing future epidemics. (cdc.gov)
  • The toxins of C. orellanus have a prolonged latent period after ingestion, which, together with the thermo- and photolability of orellanine, have hampered the development of an analytical method for the direct analytical diagnosis of C. orellanus poisoning using body fluids [ 11 , 12 ]. (hindawi.com)
  • Therefore, we performed a systematic review of published studies and reviews focusing on evaluation of laboratory methods for clinical diagnosis of human tick-borne diseases (TBDs), other than acute LB and TBE. (frontiersin.org)
  • Objectives We systematically reviewed the literature to identify evidence-informed recommendations regarding the detection of drug-induced pancreatitis (DIP) and, secondarily, to describe clinical processes for the diagnosis of DIP. (bmj.com)
  • Many detection methods have been used or reported for the diagnosis and/or surveillance of SARS-CoV-2. (biorxiv.org)
  • Varied and modern methods of caries detection are being developed, aiming to turn the diagnosis of dental caries more accurate. (bvsalud.org)
  • According to the researchers, the assay had a limit of detection of 500 femtometers, leading the authors to claim it was about "500 times more sensitive" than an unnamed analog, bead-based assay. (genomeweb.com)
  • We sought to adapt and compare a new simple molecular diagnostic method for P. knowlesi with the gold standard nested molecular assay and microscopy blood film in P. knowlesi hotspot areas in Sarawak, Malaysia. (duke.edu)
  • Please refer to the section on Choosing a PCR screening assay for VOC/VOI detection for further information on how to select the test that suits your needs. (who.int)
  • This paper describes the challenges facing firmware vulnerability detection at this stage, and introduces four automatic detection and utilization technologies in detail: based on patch comparison, based on control flow, based on data flow and ROP attack against buffer vulnerabilities. (techscience.com)
  • Finally, combined with four automatic detection methods, this paper summarizes the known vulnerability detection steps based on firmware analysis, and looks forward to the follow-up work. (techscience.com)
  • The research is focused on the development of automatic detection method of abnormal features, that occur in recorded time series of ionosphere critical frequency fOF2 during periods of high solar or seismic activity. (scirp.org)
  • The cfMeDIP-seq method - optimized from an existing low-input MeDIP-seq protocol - allows for the enrichment of CpG-rich, potentially more informative fragments, enhancing cost-effectiveness while avoiding the predetermination of PCR, the authors wrote. (genomeweb.com)
  • Its removal strongly depends on the effectiveness of its detection. (actapress.com)
  • The experimental results show the effectiveness of our detection method on images of different nature. (actapress.com)
  • However, the existing anomaly detection methods based on GNNs do not consider the temporal and spatial features of WSN data streams simultaneously, such as multi-node, multi-modal and multi-time features, seriously impacting their effectiveness. (arxiv.org)
  • The purpose of this study was to estimate the alcoholic beverage consumption among undergraduate students of a Dentistry Course and compare the effectiveness of screening methods for the detection of binge drinking. (bvsalud.org)
  • To minimize the loss suffered by banks, insurers and consumers, Dr. Bruno Buonaguidi is developing rapid detection techniques that could improve current methods, in particular by avoiding false alarms. (axa-research.org)
  • We conclude that, even in asymptomatic patients, determination of phenylpropionylglycine in urine after a phenylpropionic acid load by ion-exclusion chromatography is a rapid and reliable diagnostic tool for the detection of medium-chain acyl-CoA dehydrogenase deficiency. (nih.gov)
  • The objective of this document is to outline the available methods and tools for screening and sequencing patient specimens for the detection of VOC or VOI, with a focus on those that offer a rapid turn-around time so as to support rapid implementation of public health actions for COVID 19 control. (who.int)
  • Magnetic moment: Although neutrons have a magnetic moment of −1.9130427(5) μN, techniques for detection of the magnetic moment are too insensitive to use for neutron detection. (wikipedia.org)
  • Dermatofluoroscopy proves to be a reliable diagnostic method also for redheads. (karger.com)
  • In this sense, a number of diagnostic methods are used in daily clinical practice to establish myocardial viability. (escardio.org)
  • We recently reported the development of 2 sandwich enzyme-linked immunosorbent assays (ELISAs) for detection of SARS-CoV nucleocapsid protein in clinical specimens of SARS patients ( 10 , 11 ). (cdc.gov)
  • September 29, 2008--- A new imaging method for breast cancer has been developed by a team of scientists from Penn State using encapsulated fluorescent molecules in calcium phosphate nanoparticles and non-toxic near-infrared imaging. (laserfocusworld.com)
  • The purpose of this chapter is to describe the analytical methods that are available for detecting, measuring, and/or monitoring americium, its metabolites, and other biomarkers of exposure and effect to americium. (cdc.gov)
  • The intent is not to provide an exhaustive list of analytical methods. (cdc.gov)
  • Many of the analytical methods used for environmental samples are the methods approved by federal agencies and organizations such as EPA and the National Institute for Occupational Safety and Health (NIOSH). (cdc.gov)
  • Additionally, analytical methods are included that modify previously used methods to obtain lower detection limits and/or to improve accuracy and precision. (cdc.gov)
  • NIOSH manual of analytical methods [online]. (cdc.gov)
  • Sampling and analytical methods [online]. (cdc.gov)
  • Selected analytical methods: chemical methods query [online]. (cdc.gov)
  • Only within the last few years has CDC's laboratory been able to use high-resolution methods like genome sequencing to compare Legionella recovered from people with Legionnaires' disease to isolates from water samples. (cdc.gov)
  • Mutations in other regions of the genome may also be informative for known VOI/VOC detection. (who.int)
  • CoV-2 genome and can be targeted as a region for detection of VOC/VOI. (who.int)
  • Fig. 6: Dependence of SV detection accuracy on the level of coverage. (nature.com)
  • Despite decades of development, existing IDSs still face challenges in improving the detection accuracy, reducing the false alarm rate and detecting unknown attacks. (mdpi.com)
  • Machine learning methods can automatically discover the essential differences between normal data and abnormal data with high accuracy. (mdpi.com)
  • The researchers then developed a method to use those thermal emissions to predict defects with high accuracy. (llnl.gov)
  • A method and a device for detecting underground surrounding rock deformation belong to the technical field of surrounding rock deformation monitoring and are used for solving the problem that an existing surrounding rock deformation detecting device is low in measuring accuracy. (google.com)
  • Bauer disc diffusion method and interpreted following the CLSI 2021 guidelines. (who.int)
  • Most detection approaches rely on detecting the various reaction products. (wikipedia.org)
  • NEW YORK (GenomeWeb) - Researchers at Princess Margaret Cancer Centre and the University of Toronto have developed a new methodology for the early detection of cancer via methylated DNA. (genomeweb.com)
  • The group is not the only academic team to investigate methylation or other epigenetic changes for early cancer detection. (genomeweb.com)
  • Our approach awaits further validation in completely independent datasets, but our findings underscore the potential utility of cfDNA methylation profiles as a basis for noninvasive, cost-effective, sensitive and accurate early tumor detection for cancer interception, and for multi-cancer classification," the team concluded. (genomeweb.com)
  • Thanks to a grant of 1.990.798€ from the European Regional Development Fund and Walloon Government, we're taking part in the MENAC project which aims to develop innovative non-invasive tests for the early detection of different types of cancer. (volition.com)
  • More effective early detection of diseases is one of the promises of nanotechnology. (laserfocusworld.com)
  • and comparing the detection parameter data of different time intervals, and sending out early warning of tunnel collapse when the deformation amount of the tunnel exceeds a preset threshold value. (google.com)
  • however, subsequent studies demonstrated no utility of serial ultrasound or serial monitoring of pancreatic enzymes in the early detection of DIP. (bmj.com)
  • Methods for early detection are needed, as evidenced every day in the multidisciplinary unit for treating pregnancy-associated breast cancer, which operates within the Breast Unit at the Vall d'Hebron University Hospital in Barcelona, Spain. (medscape.com)
  • As a next step to make this finding practically useful, the research team designed a genomic panel using next-generation sequencing as a potential method for early detection of breast cancer. (medscape.com)
  • Therefore, using this panel for early detection of this type of tumor during lactation should contribute to addressing a medical need that, until today, has gone unmet," noted Vivancos. (medscape.com)
  • The findings have practical implications for early detection and intervention, potentially improving patient outcomes. (bvsalud.org)
  • This study describes the characteristics of COVID-19 case clusters in Malaysia, the method used to detect a cluster's index case and the mode of early transmission, using the seven cluster categories applied in Malaysia. (who.int)
  • Descriptive analyses were performed to explore the method used to detect the index case and the mode of early transmission, according to cluster category. (who.int)
  • Y. Polozov, O. Mandrikova and V. Bogdanov, "Detection of Anomalies in Ionospheric Increased Seismic Activity," International Union of Geodesy and Geophysics (IUGG), 28 June - 07 July 2011, Thesis, Melbourne. (scirp.org)
  • The high-performance liquid chromatography-mass spectrometry (HPLC-MS) qualitative analysis method in negative mode of detection was used to record the presence of orellanine in the stomach contents of rats after ingestion of Cortinarius orellanus . (hindawi.com)
  • The team will provide complementary expertise in IoT security, wireless networks and protocols, network traffic analysis, deep learning, parallel computing and GPU technology, outlier detection and explainable AI. (uwe.ac.uk)
  • Research on known vulnerability detection method based on firmware analysis," Journal of Cyber Security , vol. 4, no.1, pp. 1-15, 2022. (techscience.com)
  • Detection and analysis of characteristic components of time series are performed on the basis of joint application of wavelet transformation and neural networks. (scirp.org)
  • A. Polozov and T. L. Zaliaev, "Methods of Analysis and Interpretation of Ionospheric Critical Frequency FOf2 Data Based on Wavelet Transform and Neural Networks," European Seismological Commission 33-rd General Assembly (GA ESC 2012), 19-24 August 2012, Thesis, Moscow. (scirp.org)
  • The main test methods that were determined to be applicable to this study included two stress-wave propagation techniques (impact-echo and spectral analysis of surface waves techniques), infrared thermography, ground penetrating radar (GPR), and visual inspection. (cptechcenter.org)
  • Rather, the intention is to identify well-established methods that are used as the standard methods of analysis. (cdc.gov)
  • Detection software consists of analysis tools that perform tasks such as graphical analysis to measure the number and energies of neutrons striking the detector. (wikipedia.org)
  • Three hundred clinical samples were collected from male and female in and out-patients of all ages and processed using standard bacteriological methods. (who.int)
  • Methods: We developed FarNet-II, a neural network that retains some of the general characteristics of FarNet but improves the detections in general, as well as the temporal coherence among successive predictions. (iac.es)
  • In this paper, a novel anomaly detection model is proposed for multimodal WSN data flows, where three GNNs are used to separately extract the temporal features of WSN data flows, the correlation features between different modes and the spatial features between sensor node positions. (arxiv.org)
  • In this paper, a secure, lightweight, reversible, and high capacity watermarking algorithm with tamper detection capability is proposed for IoT based healthcare systems. (hindawi.com)
  • Bone metastasis detection method based on improving golden jackal optimization using whale optimization algorithm. (bvsalud.org)
  • Our review followed robust and established systematic review methods, including development and registration of an a priori protocol. (bmj.com)
  • With the Advanced Detector Era fast approaching, work is underway to develop an array of robust tools for maximizing the science and detection potential of Sco X-1. (caltech.edu)
  • Therefore, developing highly sensitive methods is imperative to ensure robust detection capabilities. (biorxiv.org)
  • An intrusion detection system (IDS) which is an important cyber security technique, monitors the state of software and hardware running in the network. (mdpi.com)
  • The second will be to develop a technology that will be used together with current methods for the detection of cyber fraud. (axa-research.org)
  • The method is based on joint application of wavelet-transformation and neural networks. (scirp.org)
  • O. Mandrikova, Y. Polozov, V. Bogdanov and E. Zhizhikina, "Method of Detection Abnormal Features in Ionosphere Critical Frequency Data on the Basis of Wavelet Transformation and Neural Networks Combination," Journal of Software Engineering and Applications , Vol. 5 No. 12B, 2012, pp. 181-187. (scirp.org)
  • A. Polozov, "Method of Training Set Formation for a Neural Network on the Basis of a Wavelet-Filtration," News of High Schools, the North Caucasian Region, a Series Natural Sciences, No. 3, 2010, pp. 12-16. (scirp.org)
  • Investigations on experimental results and criterions such as Peak Signal to Noise Ratio (PSNR) and Bit Error Ratio (BER) above 45.41 dB and 0.04, respectively, for payload of 432,538 bits indicate that the proposed method, besides providing security, being reversible, tamper detection capability, and high embedding capacity, has high imperceptibility and adequate resistance against different types of attacks. (hindawi.com)
  • Because conventional metal detectors and ground penetrating radar rely on similar same fields, it should eventually be possible to upgrade conventional systems with VENUS technology to maximize detection capability," said Dr. Josh Wetherington, principal Vadum researcher. (soldiersystems.net)
  • Machine vision methods are widely used in the industry. (rudmet.ru)
  • The widely used methods, however, are not suitable for the detection of cleaner flotation froth due to the specifics of its froth bed coloring and structure. (rudmet.ru)
  • More sophisticated detection methods account for a dramatic increase in thyroid cancer over the last 30 years, rather than a true change in occurrence of the disease, according to a study in the Journal of the American Medical Association. (diagnosticimaging.com)
  • But stable mortality rates despite the apparent rise in incidence led researchers to conclude that the increase is actually due to better detection, not greater occurrence of disease. (diagnosticimaging.com)
  • A number of tools are available for the detection of mutations that are characteristic of viruses defined as VOI/VOCs. (who.int)
  • On the basis of clarifying its core idea, main steps and experimental results, the limitations of its method are proposed. (techscience.com)
  • Throughout the review we focus particularly on the advantages and limitations of each method. (lu.se)
  • A certain binarization threshold selection method is substantiated. (rudmet.ru)
  • Before the AMD program opened the floodgates of innovation into genomic sequencing of pathogens, laboratory scientists could only subtype L. pneumophila strains using a handful of labor-intensive methods that could not always differentiate strains into distinct clusters. (cdc.gov)
  • Despite the progress made in the field of electronic fraud detection, especially artificial intelligence methods, the current cost of electronic fraud remains extremely high and is expected to increase in the future. (axa-research.org)
  • The proposed project will investigate the use of advanced artificial intelligence (AI) and machine learning (ML) methods for retrieving group traffic outliers in internet of things (IoT). (uwe.ac.uk)
  • Conclusions: The new network is a very promising tool for improving the detection of activity on the far side of the Sun given by pure helioseismic techniques. (iac.es)
  • In current methods, the normal card user pattern of expenditures is constructed and then subsequent expenditures are analyzed to determine if there are deviations," explains Dr. Bruno Buonaguidi. (axa-research.org)
  • Recently, the neural network FarNet was developed to improve these detections. (iac.es)
  • The simulation results obtained on a public dataset show that the proposed approach is able to significantly improve upon the existing methods in terms of its robustness, and its F1 score reaches 0.90, which is 14.2% higher than that of the graph convolution network (GCN) with long short-term memory (LSTM). (arxiv.org)
  • Since then, a number of enzyme systems and detection reagents have evolved. (bio-rad.com)
  • HRP systems have an advantage over other detection systems in that both the enzyme conjugate and colorimetric detection substrates are economical. (bio-rad.com)
  • RESEARCH TRIANGLE PARK, N.C. - Landmines pose a serious threat in conflict areas, yet modern detection systems struggle to discriminate between explosives and clutter. (soldiersystems.net)
  • Current imaging methods, such as x-rays and magnetic resonance imaging, are limited in the size of tumors they can detect, the depth they can penetrate the body, and by their potential side effects. (laserfocusworld.com)
  • The purpose of this research was to summarize existing nondestructive test methods that have the potential to be used to detect materials-related distress (MRD) in concrete pavements. (cptechcenter.org)
  • Lawrence Livermore National Laboratory (LLNL) engineers and scientists have developed a method for detecting and predicting strut defects in 3D-printed metal lattice structures during a print through a combination of monitoring, imaging techniques and multi-physics simulations. (llnl.gov)
  • Food: Laboratory methods [online]. (cdc.gov)
  • We compared the detection rates of 2 ELISAs and real-time qRT-PCR using the McNemar test and studied the correlation between the optical density values at 450 nm (OD 450 ) of the 2 ELISAs and log 10 viral concentrations, as determined by real-time qRT-PCR, by linear regression (SPSS version 11.0, SPSS Inc., Chicago, IL, USA). (cdc.gov)
  • The forensic methods have then been traced in literature regarding forensic science or law enforcement in order to show the correlation between those methods and the Holmes narrative. (lu.se)
  • Aims: We aim to create a new machine learning tool, FarNet-II, which further increases FarNet's scope, and to evaluate its performance in comparison to FarNet and the standard helioseismic method for detecting far-side activity. (iac.es)
  • The results from FarNet-II were compared with those obtained from FarNet and the standard helioseismic method using the Dice coefficient as a metric. (iac.es)
  • Its improvement over FarNet is higher than that of FarNet over the standard method. (iac.es)
  • however there is no standard method of detection (3). (cdc.gov)
  • Detections made through those methods are limited to strong active regions due to the need for a high signal-to-noise ratio. (iac.es)
  • A High Performance Liquid Chromatography-Mass Spectrometry (HPLC-MS) Qualitative Detection Method Developed for In Vivo Analyses of Toxin Orellanine from the Cortinarius orellanus Fr. (hindawi.com)
  • The team developed their defect detection/prediction method based on observations from the test prints, high speed imaging and multi-physics simulations of the LBPF melt pool. (llnl.gov)
  • All of the specific detection methods are fully searchable by crop, developer, product, event and protein. (isaaa.org)
  • In each method of western blot detection, a detectable signal is generated following binding of an antibody specific for the protein of interest. (bio-rad.com)
  • The various nondestructive test methods were then subjected to selection criteria that helped to reduce the size of the list so that specific techniques could be investigated in more detail. (cptechcenter.org)
  • Methods: The study was conducted at Sibu, Kapit and Sarikei Hospitals in Sarawak, Malaysia. (duke.edu)