• Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms . (lookformedical.com)
  • As a method for detecting and evaluating cervical lymph node metastasis, both palpation and imaging examinations are widely used. (biomedcentral.com)
  • Thymic epithelial neoplasms or tumors, also known as thymoma and thymic carcinoma, are the most common primary neoplasms of the anterior mediastinum. (medscape.com)
  • The current diagnostic method of gadolinium-enhanced MRI is sensitive only to larger tumors, when therapeutic options are limited. (ox.ac.uk)
  • thus, tumors with a high cell turnover are most susceptible (certain leukemias and lymphomas, small proliferating tumors, "recruited" tumor cells, and micrometastases). (doctorlib.info)
  • One of the reasons for recurrence in pathologically node-negative patients could be missed micrometastasis and occult tumor cells on routine histopathological examination or inadequate lymph node harvesting leading to understaging ( 4 ). (turkjsurg.com)
  • Twenty-six patients (12.5%) had nodal involvement: 12 (46.2%) macrometastases, six (23.1%) micrometastases, and eight (30.7%) isolated tumor cells. (bmj.com)
  • MRI is being used increasingly in determining the extent of local invasiveness of urethral neoplasms for accurate staging and preoperative planning. (medscape.com)
  • There are no scientific studies, which were performed using modern detection methods, which would identify SeV as an infectious and decease causative for humans or domestic animals. (wikipedia.org)
  • RESULTS: Of 155 patients, 115 (74%) had macrometastases and 40 (26%) micrometastases in the SLNs. (ox.ac.uk)
  • Residual axillary disease was detected in 55/155 (35%) patients with macrometastases and 4/40 (10%) with micrometastases. (ox.ac.uk)
  • As a follower of Associate Professor Krassimir Kirov, since the start of her practice, she has been performing staging sentinel biopsies in malignant melanoma and Merkel cell carcinoma, which is a leading and unique method for early surgical staging and detection of micrometastases in the regional lymphatic basin. (zapazi.me)
  • Conclusions In our setting, SLNB using methylene blue dye is also an effective method for accurately identifying SLNs in breast cancer patients and provide an accurate pathological staging without having to do a formal axillary clearance. (bvsalud.org)
  • Neoplasm staging. (lookformedical.com)
  • Sentinel lymph node (SLN) biopsy technique has been described in colon cancer to detect micrometastasis (MM) ( 6 ). (turkjsurg.com)
  • Current screening methods for ovarian cancer can only detect advanced disease. (birmingham.ac.uk)
  • As with other imaging modalities, MRI is unable to detect micrometastases and cannot definitively determine prognosis. (medscape.com)
  • Renal cell carcinoma (RCC), the most common kidney neoplasm, originates in renal tubular epithelial cells and accounts for 85-90% of adult renal malignancies [ 1 ]. (biomedcentral.com)
  • METHODS: Patients with advanced gastroesophageal adenocarcinoma from the AGAMENON-SEOM registry treated with first-line polychemotherapy between January 2008 and October 2022 were included. (bvsalud.org)
  • Using Univariable Cox regression analysis and Lasso regression analysis method in the training dataset, it was found that the four DNA methylation markers ( CCNT1 , ITGB3 , SDS , and HMOX2 ) were significantly correlated with the overall survival of patients with PDAC. (aging-us.com)
  • Methods Single-center retrospective evaluation of consecutive patients who underwent SLN mapping following hysteroscopic peritumoral injection of tracer. (bmj.com)
  • The impact of nodal micrometastases demonstrated by molecular assays and adjuvant therapy on survival of patients with stage I pancreatic cancer has not been adequately assessed. (johnshopkins.edu)
  • Survival did not differ for patients with molecular micrometastases. (johnshopkins.edu)
  • The majority of patients with stage I pancreatic cancer have PCR/RFLP evidence of lymph node micrometastases. (johnshopkins.edu)
  • Adjuvant chemoradiation improves survival in these patients by treating micrometastases not detected by histology. (johnshopkins.edu)
  • The purpose of our study was to develop modern epidemiological data for adult patients completing an appendectomy for UA secondary to an appendiceal neoplasm (AN). (cancerindex.org)
  • Methods: 351 patients with curatively resected pancreatic adenocarcinoma (PC) from three center hospitals were entered into this multicenter cohort study. (researchsquare.com)
  • METHODS: Patients who underwent cALND following a positive SLN were analysed for histopathological features of the primary tumour and burden of axillary disease. (ox.ac.uk)
  • CONCLUSION: Patients may be advised to forgo cALND where the SLN contains isolated tumour cells or micrometastasis. (ox.ac.uk)
  • Using current diagnostic methods, we are still unable to identify patients especially prone to metastases. (czytelniamedyczna.pl)
  • Hricak et al (1991) used MRI for diagnostic evaluation of the female urethra in a series of patients and found that primary or metastatic urethral neoplasms were detected in every patient who was clinically found to have disease. (medscape.com)
  • Materials and Methods Twenty-five patients with confirmed fine needle aspiration cytological diagnosis of breast cancer, who were undergoing planned mastectomy and axillary node clearance, were included in the study. (bvsalud.org)
  • Materials and Methods: From November 2008 to April 2009, consecutive patients presenting to the Accident & Emergency department or the surgical wards with right iliac fossa pain were recruited for the study. (bvsalud.org)
  • Despite surgical removal of the cancer, many patients with ovarian cancer will already have microscopic cancer cells, called micrometastases that have spread away from the ovary to other locations in the abdomen and distant parts of the body. (yourcancercare.com)
  • Micrometastases, lobular histology and preoperative chemotherapy were associated with a higher rate of incorrect negative results. (nih.gov)
  • The presence of such cells in the blood coexists with micrometastases, which are clinically silent, and/or precedes the clinical emergence of metastases (4). (czytelniamedyczna.pl)
  • Therefore, the early detection of postoperative micrometastases and recurrent lesions, and overcoming RCC drug resistance can improve patient prognosis. (biomedcentral.com)
  • Of particular interest are adjuvant therapy, treatment of metastatic disease, methods for treatment of locally advanced breast cancer and inflammatory breast cancer. (stanford.edu)
  • To identify early driver mutations in ovarian cancer cells, we used dense whole genome sequencing of micrometastases and microscopic residual disease collected at three time points over three years from a single patient during treatment for high-grade serous ovarian cancer (HGSOC). (birmingham.ac.uk)
  • Nasopharyngeal carcinoma (NPC) is a rare head and neck neoplasm worldwide. (intechopen.com)
  • In cell biology, individual micrometastases have been observed to have reduced growth rates below a threshold size, which suggests that the presence of additional cells enhances the birth rate 12 . (nature.com)
  • Neoplasms containing cyst-like formations or producing mucin or serum. (lookformedical.com)
  • The presence of micrometastasis in bone marrow was closely related to vascular endothelial growth factor positivity and microvessel density in the primary gastric cancer. (elsevierpure.com)
  • Methods which attempt to express in replicable terms the extent of the neoplasm in the patient. (lookformedical.com)
  • Currently, surgical resection is the most effective method for PDAC treatment. (aging-us.com)
  • Importantly, expression of VCAM-1 was shown in human brain tissue containing both established metastases and micrometastases. (ox.ac.uk)
  • Ability of neoplasms to infiltrate and actively destroy surrounding tissue. (lookformedical.com)
  • Abnormal growths of tissue that follow a previous neoplasm but are not metastases of the latter. (lookformedical.com)
  • METHODS: We implemented VIGex using the nCounter platform (Nanostring) on a large clinical cohort encompassing 909 tumor samples across 45 tumor types. (bvsalud.org)
  • The development of the second neoplasm may or may not be related to the treatment for the previous neoplasm since genetic risk or predisposing factors may actually be the cause. (lookformedical.com)
  • 2mm (micrometastasis) SLN group. (ox.ac.uk)
  • We studied 5 consecutive cases of GCT involving the distal radius operated by en-bloc resection of tumor followed by reconstruction with ipsilateral non-vascularized fibular graft with a minimum 1 year follow-up. (jbstjournal.com)
  • The second neoplasm may have the same or different histological type and can occur in the same or different organs as the previous neoplasm but in all cases arises from an independent oncogenic event. (lookformedical.com)
  • Although recent computational methods for predicting the strengths of these interactions appear promising [20,2932], information on the relative contribution of individual residues to wlrk stabilization can only be reliably obtained at the present time through actual affinity measurements of site-directed mutants of the interacting species. (binaryoptiontradingscam.com)
  • The goals of pharmacotherapy are to reduce morbidity and to eradicate the neoplasm. (medscape.com)
  • The neoplasms may be histologically the same or different, and may be found in the same or different sites. (lookformedical.com)