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  • high methionine
  • The group with the high methionine diet also had up to 40 percent more amyloid plaque in their brains, which is a measurement of how much Alzheimer's disease has developed. (redorbit.com)
  • protein
  • The L- isomer of methionine, which is the only form that is involved in protein synthesis, is one of the 20 standard amino acids common in animal proteins and required for normal functioning in humans . (newworldencyclopedia.org)
  • Meat and other high-protein foods are rich in methionine. (livestrong.com)
  • Di Pasquale cited a French study in which rats that were fed a soy protein diet showed a sharp increase in the peroxidation of lipids that was at least partially reversed when researchers supplemented the test animals' diets with methionine. (livestrong.com)
  • Methionine enters the cycle primarily from diet, but it can also be salvaged from endogenous protein degradation. (nih.gov)
  • Fischer et al, ChemBioChem, Synthesis of a 13C-Methyl-Group-Labeled Methionine Precursor as a Useful Tool for Simplifying Protein Structural Analysis by NMR Spectroscopy, 2007, 8, pp. 610-612. (freepatentsonline.com)
  • The oxidation of methionine serves as a switch that deactivates certain protein activities such as E.coli ribosomal protein, L12. (wikipedia.org)
  • Patton, R.A. "Effect of rumen-protected methionine on feed intake, milk production, true milk protein concentraition, and true milk protein yield, and the factors that influence these effects: A meta-analysis. (wikipedia.org)
  • diets
  • To better understand the effects of methionine deficiency on the liver, a team of researchers at the University of Kentucky Medical Center conducted an animal study in which they fed lab rats diets that were either very low or totally lacking in methionine. (livestrong.com)
  • However, when methionine-rich diets are used to induce hyperhomocysteinemia, vascular pathology is often observed. (nih.gov)
  • deficiency
  • A deficiency of methionine can trigger symptoms ranging from elevated cholesterol readings to liver damage. (livestrong.com)
  • In an article in the March 2008 issue of "Digestive Diseases and Sciences," researchers said their findings confirmed the causative role that methionine deficiency plays in the development of steatohepatitis, also known as fatty liver. (livestrong.com)
  • Di Pasquale said the test findings suggest that an imbalance of amino acids, particularly a deficiency of methionine, can lead to an elevated risk of atherosclerosis through increased circulating cholesterol and increased lipid susceptibility to peroxidation. (livestrong.com)
  • A deficiency of methionine leads to reduced levels of SAM and an increased risk of depression. (livestrong.com)
  • Although methionine deficiency can produce unpleasant symptoms, consuming excessive levels of the amino acid can produce adverse consequences as well. (livestrong.com)
  • Deficiency is unlikely because enough methionine is generally available from the diet. (winchesterhospital.org)
  • mRNA
  • Methionine is coded for by the initiation codon, meaning it indicates the start of the coding region and is the first amino acid produced in a nascent polypeptide during mRNA translation. (wikipedia.org)
  • sulfonium
  • A sulfonium compound that is the S -adenosyl derivative of L -methionine. (ebi.ac.uk)
  • SAM is composed of an adenosyl molecule (via 5' carbon) attached to the sulfur of methionine, therefore making it a sulfonium cation (i.e., three substituents and positive charge). (wikipedia.org)