• Tumor-to-tumor metastasis is a rare phenomenon in which primary tumor cells metastasize to other tumors. (bvsalud.org)
  • Herein, we report an extremely rare case of tumor-to-tumor metastasis of medullary thyroid carcinoma to a paraganglioma in a patient with multiple endocrine neoplasia type 2B. (bvsalud.org)
  • The liver lesion was diagnosed as a metastasis of the medullary thyroid carcinoma. (bvsalud.org)
  • This is the first report of tumor-to-tumor metastasis of medullary thyroid carcinoma to paraganglioma in a patient with multiple endocrine neoplasia type 2B twenty years after total thyroidectomy. (bvsalud.org)
  • Metastasis of clear cell renal cell carcinoma (ccRCC) to the thyroid gland is rare, and simultaneous occurrence of ccRCC and papillary thyroid carcinoma (PTC) is even rarer. (spandidos-publications.com)
  • In the case of multiple tumors, the possibility of thyroid metastasis should not be ignored during the clinical diagnosis and treatment of PTC. (spandidos-publications.com)
  • However, thyroid metastasis of ccRCC combined with papillary thyroid carcinoma (PTC) is rarely reported. (spandidos-publications.com)
  • After the operation, the pathological examination results suggested the following: Renal clear cell carcinoma, pT1aN0M0, the tumor sized ~4.0×4×3.5 cm 3 , with no lymph node cancer metastases or distant metastasis. (spandidos-publications.com)
  • HLRCC-associated kidney cancer is an aggressive tumor characterized by early metastasis to regional lymph nodes and distant organs. (biomedcentral.com)
  • Note that presence of tumor within the adrenal gland is not interpreted as metastasis. (pedsurglibrary.com)
  • 1 Although majority of the patients present with localised disease, approximately 30% of patients are diagnosed with metastasis 2 and another 30% of patients develop metastasis after radical nephrectomy. (medcraveonline.com)
  • However, local recurrence or distant metastasis still occur in some patients even after radical nephrectomy. (biomedcentral.com)
  • These are as follows: sustained proliferative signalling, cell death resistance, replicative immortality, genome instability and increased mutations, tumour-promoted inflammation, insensibility to growth repressors, deregulation of cellular energetics, evasion of immune destruction, induction of metastasis, and promotion of angiogenesis. (hindawi.com)
  • Renal masses are a biologically heterogeneous group of tumors, ranging from benign masses, to indolent cancers that behave in a benign fashion, and finally, extremely aggressive and deadly cancers. (ahrq.gov)
  • In this chapter, these will be covered using an approach that has become a standard one in dealing with this group of tumors. (abdominalkey.com)
  • 4 While renal cell carcinoma only represents 2% of adult cancers, it is among the most lethal, with approximately 35% of patients dying within 5 years of diagnosis. (ahrq.gov)
  • Histological examination revealed the classic Zellballen pattern in the retroperitoneal tumor, rendering the diagnosis of a paraganglioma recurrence. (bvsalud.org)
  • A left renal mass was detected on computerized tomography (CT) scan followed by a histopathological diagnosis of MTSCC with 70% tumor showing the sarcomatoid change. (biomedcentral.com)
  • A diagnosis of SDH-deficient RCC required loss of staining in all tumour cells in the presence of internal positive controls. (sajo.org.za)
  • Since early diagnosis and provision of definitive therapy is thought to be the best way to reduce the tumor burden, it is widely accepted that germline testing and active surveillance for an at-risk individual from a family with HLRCC is very important. (biomedcentral.com)
  • Bilateral renal involvement by tumor is present at diagnosis. (pedsurglibrary.com)
  • In recent years, multiple agents have been developed for systemic treatment of metastatic disease. (medscape.com)
  • Materials and Methods: From March 1996 to February 2001, 36 patients underwent cytoreductive laparoscopic radical nephrectomy at our institution in preparation for systemic immunotherapy. (elsevierpure.com)
  • 8 However, the deaths due to renal cell carcinoma are driven by the failure of systemic treatments in metastatic (later stage) patients. (ahrq.gov)
  • Parathyroid carcinoma (PC) is a rare endocrine malignancy with no approved systemic therapies for unresectable locally invasive or distant metastatic disease. (cancerindex.org)
  • Whether these markers of systemic inflammation play any role in the incitation of these renal tumours as observed in our study is yet to be known. (medcraveonline.com)
  • BACKGROUND: Medullary carcinoma of the colon is a rare subtype of colorectal cancer that has a unique, and sometimes varied, clinical and histologic profile. (bvsalud.org)
  • The histopathologic evaluation of the resected specimens showed invasive carcinoma with syncytial growth pattern, foci of lymphoid host response, and dirty necrosis, in keeping with a medullary carcinoma pT4a pN2b. (bvsalud.org)
  • Unlike most reported medullary carcinoma cases, this patient was young and caudal-related homeobox transcription factor 2 positive. (bvsalud.org)
  • CONCLUSION: We have reported another case of medullary carcinoma of the colon in a young patient with unique histologic characteristics. (bvsalud.org)
  • Reporting such cases helps in refine understanding of the histologic and genetic, as well as clinical, phenotypes of medullary carcinoma of the colon. (bvsalud.org)
  • BACKGROUND: Renal medullary carcinoma (RMC) is a very rare, aggressive neoplasm occurring almost exclusively in adolescents and young adults with sickle cell trait. (bvsalud.org)
  • Renal cell carcinoma (see the image below) is the most common type of kidney cancer in adults. (medscape.com)
  • See Renal Cell Carcinoma: Recognition and Follow-up , a Critical Images slideshow, to help evaluate renal masses and determine when and what type of follow-up is necessary. (medscape.com)
  • Renal cell carcinoma may remain clinically occult for most of its course. (medscape.com)
  • Surgical resection remains the only known curative treatment for localized renal cell carcinoma, and it is also used improve outcome or for palliation in metastatic disease. (medscape.com)
  • Renal cell carcinoma (RCC) accounts for approximately 3% of adult malignancies and 90-95% of neoplasms arising from the kidney. (medscape.com)
  • Increasingly, renal cell cancers are diagnosed at an earlier stage, and nephron-sparing surgery, thermal ablation, and surveillance are gaining acceptance as a treatment of choice for smaller tumors. (medscape.com)
  • Go to Clear Cell Renal Cell Carcinoma and Sarcomatoid and Rhabdoid Renal Cell Carcinoma for complete information on these topics. (medscape.com)
  • The tissue of origin for renal cell carcinoma (RCC) is the proximal renal tubular epithelium. (medscape.com)
  • Surgical resection remains the only known effective treatment for localized renal cell carcinoma, and it is also used for palliation in metastatic disease. (medscape.com)
  • Renal cell carcinoma develops in nearly 40% of patients with von Hippel-Lindau disease and is a major cause of death among these patients. (medscape.com)
  • Deletions of 3p occur commonly in renal cell carcinoma associated with von Hippel-Lindau disease. (medscape.com)
  • All patients had renal cell carcinoma with documented metastatic disease. (elsevierpure.com)
  • Renal cell carcinoma (RCC) and urothelial cell carcinoma (UCC) are the two most common types of kidney cancer. (ahrq.gov)
  • All solid renal masses and cystic lesions with solid components are suspicious for renal cell carcinoma. (ahrq.gov)
  • No test is effective at screening for renal cell carcinoma, and most tumors are detected incidentally during an evaluation for unrelated or non-specific complaints. (ahrq.gov)
  • Determination of subtypes of cystic renal cell carcinomas by imaging is still challenging due to overlap of common imaging features. (radiologykey.com)
  • Complex cysts, on imaging, may be seen as part of benign cysts, renal infection, and cystic neoplasms, including cystic renal cell carcinoma (RCC), which can be distinctly identified due to characteristic imaging features. (radiologykey.com)
  • Renal cell carcinoma (RCC) is the most common solid lesion within the kidney and accounts for ~90% of all kidney malignancies. (spandidos-publications.com)
  • Mucinous tubular and spindle cell carcinoma (MTSCC) is a type of renal cell carcinoma (RCC) described as an entity with low-grade and low malignant potential. (biomedcentral.com)
  • There are various types of renal cell carcinomas with distinct underlying molecular features, unique immunophenotypes, varying degrees of clinical outcomes, and therapeutic implications. (biomedcentral.com)
  • Originally, mucinous tubular and spindle cell carcinoma (MTSCC) was described as an unclassifiable tumor in 1998 (Lima et al. (biomedcentral.com)
  • Succinate dehydrogenase-deficient (SDH-deficient) renal cell carcinoma (RCC) is a rare subtype of RCC. (sajo.org.za)
  • Succinate dehydrogenase- (SDH)-deficient renal cell carcinoma (RCC) is a rare subtype of RCC, estimated to comprise 0.05% - 0.2% of all cases of RCC globally. (sajo.org.za)
  • The classification of epithelial tumors of the kidney has in particular undergone substantial progress in the last two decades with major contributions from genetic typing of renal cell carcinomas (RCCs). (abdominalkey.com)
  • The role of genotyping and ancillary tools, in particular immunohistochemistry, in correctly classifying these tumors is highlighted in the section on Renal Cell Carcinoma. (abdominalkey.com)
  • Compensatory structural and functional adaptation after radical nephrectomy for renal cell carcinoma according to preoperative stage of chronic kidney disease. (psu.edu)
  • Treatment for renal cell cancer is tailored to each individual and may include surgery, precision cancer medicines, immunotherapy and/or chemotherapy. (yourcancercare.com)
  • Radiation therapy is not typically used for the treatment of renal cell cancer. (yourcancercare.com)
  • Patients with early stage renal cell cancer are curable with surgical removal of the cancer. (yourcancercare.com)
  • Partial nephrectomy, which is removal of only the cancer and a small border of normal tissue, is the standard treatment for the smallest cancers however patients will require a radical nephrectomy, or removal of the entire kidney for larger renal cell cancers. (yourcancercare.com)
  • The following are simplified definitions of the various stages of renal cell cancer. (yourcancercare.com)
  • Hereditary leiomyomatosis and renal cell carcinoma (HLRCC) is an autosomal dominant tumor susceptibility syndrome, and the disease-related gene has been identified as fumarate hydratase (fumarase, FH ). (biomedcentral.com)
  • What's New in the Field of Neoadjuvant Therapy and Renal Cell Carcinoma? (medscape.com)
  • Welcome to season 2 of Medscape's InDiscussion series on renal cell carcinoma (RCC). (medscape.com)
  • The most highly vascularized vertebrae are those with metastases originating from renal cell and thyroid carcinoma [7]. (123dok.net)
  • Sporadic renal cell carcinoma in young and elderly patients: are there different clinicopathological features and disease specific survival rates? (biomedcentral.com)
  • Sporadic renal cell carcinoma (RCC) is rare in young adults. (biomedcentral.com)
  • Renal cell carcinoma (RCC) is the most common renal parenchymal malignancy and represents 3% - 6% of all adult malignancies [ 1 ]. (biomedcentral.com)
  • Renal cell carcinoma (RCC) accounts for about 3% of all malignancies. (medcraveonline.com)
  • Renal cell carcinoma (RCC) is one of the most common solid neoplasm of urinary tract accounting for about 3% of all malignancies in adult. (medcraveonline.com)
  • INTRODUCTION: Sunitinib is a multi-targeted receptor tyrosine kinase inhibitor used to treat metastatic renal cell carcinoma (mRCC). (bvsalud.org)
  • Clear cell renal cell carcinoma is one of the most interesting areas of study in oncology right now. (mdpi.com)
  • Renal cell carcinoma (RCC) is the most common malignant kidney tumor and has a high incidence rate. (biomedcentral.com)
  • Renal cell carcinoma (RCC), the most common kidney neoplasm, originates in renal tubular epithelial cells and accounts for 85-90% of adult renal malignancies [ 1 ]. (biomedcentral.com)
  • Sagittal and transverse B-mode US images show left renal cyst with thin smooth internal septations ( A ), which does not show internal vascularity on color doppler image ( B ). Coronal T2W images ( C ) show left renal cyst with smooth thin wall and septations. (radiologykey.com)
  • CT scan (Fig. 1 ) abdomen showed well-defined heterogeneously relatively hypo-enhancing, ball-shaped, left renal mass with loss of fat interface with adjacent large bowel, compressing and displacing pelvicalyceal system with no definite vascular extension. (biomedcentral.com)
  • Multiple enlarged upper abdominal and left renal hilar lymph nodes were seen. (biomedcentral.com)
  • A 48-year-old woman with a left renal tumor and involvement of multiple regional lymph nodes with high accumulation of fluorine-18-deoxyglucose on positron emission tomography was treated with axitinib as a neoadjuvant therapy. (biomedcentral.com)
  • Preoperative patient and tumor (imaging) characteristics are used to stratify the risk of benign versus malignant disease, and indolent versus aggressive cancers. (ahrq.gov)
  • Preoperative axitinib induced the shrinkage of the tumor with decreased fluorine-18-deoxyglucose accumulation. (biomedcentral.com)
  • aspects of vertebral tumor embolization [1, 7] and showed the efficacy of preoperative embolization on perioperative blood loss [3,4, 10]. (123dok.net)
  • The safety of preoperative embo-lization and the tumor resectability in the surgeons' appreciation is evaluated. (123dok.net)
  • Morphologically, the tumor was composed of tubular structures lined by cuboidal cells mixed with spindle cells and sarcomatoid change was present in the tumor. (biomedcentral.com)
  • Histological analysis revealed a tumor comprised of tubular structures set in a mucinous background. (biomedcentral.com)
  • Targeted therapy and immunomodulatory agents are considered standard of care in patients with metastatic disease. (medscape.com)
  • In recent years, clinical trials have established targeted therapy as the first-line treatment in patients with metastatic disease. (medscape.com)
  • Results: In 3 patients a portion of the diaphragm was dissected via laparoscopy during debulking nephrectomy. (elsevierpure.com)
  • 4 This may be reflective of the stable rates of patients presenting with advanced and metastatic cancer, a changing biology of kidney cancer, or the overtreatment of indolent lesions with resultant complications of that treatment. (ahrq.gov)
  • Demographic, clinical and imaging characteristics are used to risk-stratify patients, and nomograms exist that combine these characteristics into composite models to classify tumors preoperatively. (ahrq.gov)
  • Contrast-enhanced ultrasound evaluation is a safe alternative imaging modality for the assessment of complex cystic renal masses in patients with renal impairment. (radiologykey.com)
  • Since its introduction in 1986, Bosniak classification for renal cysts has been used by radiologists and urologists as a method to stratify patients to plan treatment. (radiologykey.com)
  • These patients require several follow-up examinations for longitudinal evaluation, allowing the natural course of growth to reveal a neoplasm warranting intervention. (radiologykey.com)
  • Given the rare nature of this tumor, accounting for less than 0.5% of all renal carcinomas, most of the published data on therapies is from case reports and small case series, and current treatments are insufficient, with most patients succumbing to their disease in months. (bvsalud.org)
  • A radical nephrectomy was performed on all patients. (bvsalud.org)
  • A high index of suspicion should be maintained with an aim of surgical treatment for selected patients with large and symptomatic adrenal lipomatous lesions. (bmj.com)
  • Patients with Beckwith-Wiedemann syndrome and Denys-Drash syndrome have an increased risk of developing Wilms tumor ( 5 , 6 ). (abdominalkey.com)
  • As you know, at around the time, almost 10 years ago, some of these neoadjuvant trials had not mandated biopsy, so we had patients with benign tumors or different types of histologies. (medscape.com)
  • We had, I believe, 11 out of 24 patients with a partial response - about 46% of patients who had a partial response by the response evaluation criteria in solid tumors (RECIST) criteria - which was quite encouraging, with a relatively short duration of therapy. (medscape.com)
  • In this paper we report our personal experience with the embolization of hypervascular vertebral tumors in a series of 24 patients. (123dok.net)
  • Sporadic RCC in young patients have lower tumor stages and grades and a better outcome compared to elderly. (biomedcentral.com)
  • In other tumor entities it has been noted that younger adults often have a less favorable prognosis than elderly patients. (biomedcentral.com)
  • Between 1992 and 2005 a total of 1042 patients underwent partial or radical nephrectomy for renal masses at the Department of Urology of the University of Regensburg. (biomedcentral.com)
  • 75 years) to avoid masking any potential differences in tumor biology between young and old patients. (biomedcentral.com)
  • All the patients fulfilling the inclusion criteria were subjected to partial or radical nephrectomy and the specimen were sent for histopathological examination. (medcraveonline.com)
  • PATIENTS AND METHODS: We herein describe in detail the first cases published of the above-mentioned renal malignancies associated with extensive inferior vena cava (IVC) thrombus, in which complex vascular reconstruction was performed. (bvsalud.org)
  • RESULTS: Three male patients were identified as having collecting duct carcinoma, epithelioid angiosarcoma and neuroendocrine/carcinoid tumor with IVC involvement. (bvsalud.org)
  • METHODS: This retrospective trial consisted of 52 consecutive patients who underwent radical prostatectomy. (kocaelimj.org)
  • 1,2 The true incidence of renal masses (including benign lesions) is unknown, but benign lesions comprise approximately 20% of surgically resected tumors. (ahrq.gov)
  • The retroperitoneal and liver tumors were surgically resected and examined by a pathologist. (bvsalud.org)
  • We successfully treated the patient with locally advanced HLRCC-associated kidney cancer, who has received active surveillance because of at-risk individual, by radical nephrectomy and extended retroperitoneal lymph node dissection, and examined surgically resected samples from a molecular point of view. (biomedcentral.com)
  • The rate of lymph node metastases or distant metastatic disease at presentation did not differ significantly between both groups. (biomedcentral.com)
  • To our knowledge intentional resection of the diaphragm during laparoscopic radical nephrectomy for large renal tumors has not yet been described. (elsevierpure.com)
  • Charts and operative tapes were reviewed and cases were identified in which diaphragmatic resection was performed for locally invasive tumors. (elsevierpure.com)
  • Later, while waiting for elective resection, the patient developed symptoms and signs of a large bowel obstruction. (bvsalud.org)
  • In April 2018, the patient underwent radical resection of the left kidney for ccRCC at Xinqiao Hospital, Third Military Medical University (Chongqing, China). (spandidos-publications.com)
  • The sur-geons concluded that radical tumor resection after embolization was facilitated. (123dok.net)
  • Preop-erative embolization of vertebral hypervascular tumors is safe, effec-tive and facilitates tumor resection. (123dok.net)
  • Surgical resection is performed and pathologic evaluation shows completely resected Wilms tumor with focal penetration of the renal capsule. (pedsurglibrary.com)
  • 11 Locally advanced cancers have a significantly worse prognosis than localized tumors. (ahrq.gov)
  • Cystic renal tumors, overall, have excellent prognosis and less aggressive metastatic behavior compared with solid renal tumors. (radiologykey.com)
  • Owing to the rarity of the above-mentioned malignancies and short follow-up of the cases published in the literature, the prognosis and clinical behavior of these tumors remains unclear. (bvsalud.org)
  • On gross examination, a 10.5 × 9.0 × 6.0 cm well-circumscribed tumor mass was found at the lower pole with necrosis on the cut surface. (biomedcentral.com)
  • Almost 70% of the tumor showed sarcomatoid differentiation and tumor necrosis was also present. (biomedcentral.com)
  • Resected samples showed two thirds tumor tissue necrosis as well as high expression of serine/threonine kinase Akt and low expression of nuclear factor E2-related factor 2 (Nrf2) which activates anti-oxidant response and protects against oxidative stress in viable cancer cells. (biomedcentral.com)
  • With this background in mind, we carried out a prospective study to find out any association between the inflammatory markers and renal tumour characteristics like histology, tumour size, presence of necrosis and calcification. (medcraveonline.com)
  • The histology and tumour characteristics like tumour size, presence of necrosis and calcification were then correlated with the above mentioned prognostic variables of RCC. (medcraveonline.com)
  • 1] It accounts for approximately 3% of adult malignancies and 90-95% of neoplasms arising from the kidney. (medscape.com)
  • BACKGROUND/AIM: Collecting duct carcinoma, epithelioid angiosarcoma and neuroendocrine/carcinoid tumor are uncommon renal malignancies, and their association with tumor thrombus extending into the inferior vena cava is extremely rare. (bvsalud.org)
  • Ours is a landmark study correlating inflammatory markers with various renal tumour histological characteristics. (medcraveonline.com)
  • INTRODUCTION: The objective of this current study was to compare the histological findings of 12-core transrectal ultrasound (TRUS) guided prostate biopsy results with that of corresponding radical prostatectomy specimens. (kocaelimj.org)
  • The diagnostic ability of biopsy cores, cancer locations and the histological findings particularly Gleason grades of 12-core biopsies were compared with that of radical prostatectomy specimens. (kocaelimj.org)
  • Radical nephrectomy is the standard for larger and central tumors. (medscape.com)
  • Larger or central tumors are more likely to be invasive, but small peripheral tumors may also be invasive. (ahrq.gov)
  • He has dedicated his clinical practice to the surgical management of metastatic disease, particularly to the liver and peritoneum. (stanford.edu)
  • Abstract The aim of this study was to evaluate the impact of preopera-tive devascularization of spinal metastases in relation to the pre-embolization tumor vascularization degree and in relation to the intra-operative blood loss. (123dok.net)
  • Renal mass sampling can be done by fine needle aspiration with a reading of the sample by a cytopathologist, or by core biopsy with a reading of the sample by a surgical pathologist. (ahrq.gov)
  • Multi-quadrant biopsy technique improves diagnostic ability in large heterogeneous renal masses. (psu.edu)
  • Unilateral disease on biopsy was mostly associated with bilateral cancer on corresponding radical prostatectomy specimen. (kocaelimj.org)
  • She had a history of total thyroidectomy for medullary thyroid carcinoma and bilateral adrenalectomy for pheochromocytomas, which were performed when she was 15 years and 29 years old, respectively. (bvsalud.org)
  • A case of a 23-year-old male is discussed with an incidental renal mass in the left kidney after a workup of bilateral flank pain. (biomedcentral.com)
  • However about 71% of these cases was bilateral disease on radical prostatectomy specimens. (kocaelimj.org)
  • 3, 16-18 The best predictors of malignancy are male sex and tumor size, although computed tomography (CT) enhancement patterns have also been able to predict histology in up to 85% of cases. (ahrq.gov)
  • Follow-up computed tomography demonstrated a retroperitoneal tumor of 30 mm in diameter beside the left kidney and a liver tumor of 16 mm in diameter located in segment 6. (bvsalud.org)
  • World Health Organization Classification of Tumors: Pathology and Genetics of Tumors of Soft Tissue and Bone, 2002). (curehunter.com)
  • A family of mesenchymal tumors composed of histologically and immunohistochemically distinctive perivascular epithelioid cells. (curehunter.com)
  • Imaging plays a critical role in management, differentiating benign cysts, which do not require treatment, from cystic neoplasms, which may benefit from partial or radical nephrectomy, or percutaneous ablation under imaging guidance. (radiologykey.com)
  • Bosniak classification is based on findings on contrast-enhanced CT scans, dividing renal cysts into 4 broad categories (I-IV) proposed to distinguish malignant from benign cystic lesions. (radiologykey.com)
  • Commonly encountered cysts on ultrasound (US) and cross-sectional imaging (CT and MR imaging) mostly are benign simple cortical renal cysts. (radiologykey.com)
  • ccRCC has previously been reported to metastasize to normal thyroid tissue ( 7 ) or benign thyroid tumors ( 8 ). (spandidos-publications.com)
  • Up to date, the culprit of treatment is surgical management with radical nephrectomy, lymph node dissection, thrombectomy and vascular reconstruction if necessary. (bvsalud.org)
  • After years of accumulation, the program "series studieson modified surgical method in radical cystectomy and urinary diversion",directed by Professor Zhou Fangjian, was awarded the third prize in science and technology progress by Guangdong Anti-Cancer Association in 2012. (sysucc.org.cn)
  • Radical cystectomy + modified ileal neobladder (international advanced level): We have modified the classical surgical method with shortened the operation time reduced complications on the premise of ensuring excision extension and radical treatment. (sysucc.org.cn)
  • This surgical modification facilitates the radical cystectomy + modified ileal neobladder operation to be accomplished in about 4 hours. (sysucc.org.cn)
  • The surgical method has become a major urological neoplasm operation for doctorsfrom all provinces to learn and then perform in their local areas. (sysucc.org.cn)
  • The surgical method has become a major urological neoplasm operation for doctors from all provinces to learn and then perform in their local areas. (sysucc.org.cn)
  • Genetic studies of the families at high risk for developing renal cancer led to the cloning of genes whose alteration results in tumor formation. (medscape.com)
  • b) blood vessels within the specimen outside of the parenchyma contain tumor. (pedsurglibrary.com)
  • 1, 19-21 In addition, all current standard imaging modalities (CT, magnetic resonance imaging (MRI) and ultrasound) are able to provide insight into whether renal masses are localized or locally advanced, thus suggesting pathologic aggressiveness. (ahrq.gov)
  • This is followed by coverage of neoplasms in the more traditional categories of epithelial, mesenchymal, and other categories. (abdominalkey.com)
  • 5 The greatest increase in incidence was noted in small, clinically-localized tumors (i.e. tumors within the kidney with no evidence of local spread, lymph node involvement or distant metastases), now upwards of 40% of all kidney cancers. (ahrq.gov)
  • The peritoneum is a common site of metastases for gastrointestinal tumors that predicts a poor outcome. (stanford.edu)
  • Most common primary tumors of vertebral metastases are localized in the breast, lung, prostate and kidney. (123dok.net)
  • 9, 10 Importantly, approximately 40% of clinically localized tumors are determined to be locally-advanced cancers (stage T3, with invasion of perinephric fat or venous structures) at pathological examination. (ahrq.gov)
  • Alcohol consumption and the risk of renal cancers in the European Prospective Investigation into Cancer and Nutrition (EPIC). (psu.edu)
  • Chemotherapy is used only occasionally, in certain tumor types. (medscape.com)
  • Although the tumour is often indolent, it has a strong association with hereditary disease, most commonly paraganglioma and/or pheochromocytoma, and genetic testing is advised. (sajo.org.za)
  • Genetic profiling as a clinical tool in advanced parathyroid carcinoma. (cancerindex.org)
  • To evaluate tumor-specific genetic changes using next-generation sequencing (NGS) panels. (cancerindex.org)
  • Current theories of tumor development suggest a genetic mutation that predisposes to the persistence of nephrogenic rests. (pedsurglibrary.com)
  • the treatment of bladder cancer, kidney cancer and penis cancer is of high international level, and the therapeutic effect of prostate cancer, testicular neoplasms, pelvic ureteral carcinoma and other diseases is outstanding all over the country, which make our department among the most standardized organizations in treating tumors of male urological and reproductive system. (sysucc.org.cn)
  • In each case, the clinical presentation, location of the tumour, and the outcome for the patient were studied. (bmj.com)
  • In wake of complete clinical, laboratory, and radiological assessment left radical nephrectomy and adrenalectomy with lymph node dissection was performed. (biomedcentral.com)
  • A 52 year male undergoing elective coronary artery bypass grafting was incidentally discovered to have a large soft tissue mass of variable consistency with cartilaginous elements arising from the right costal margin and adjoining ribs by a broad attachment and protruding into right pleural cavity. (biomedcentral.com)
  • Pathological evaluation was reviewed and tumor stage was adapted according to the 2002 TNM classification. (biomedcentral.com)
  • CT scan chest showed tiny pulmonary nodules suspicious to be metastatic. (biomedcentral.com)
  • Percutaneous renal mass sampling is offered as a diagnostic adjunct to traditional axial imaging with contrast. (ahrq.gov)
  • Modified radical lymph node dissection of groin (international advanced level): High incidence of complications after operation is a drawback of traditional dissection of groin lymph node. (sysucc.org.cn)
  • Here, we report a unique case of young male patient who initially presented with abdominal pain followed by a large bowel obstruction. (bvsalud.org)
  • Wiedemann-Beckwith syndrome is related to abnormalities on chromosome 11p15 and characterized by multiple craniofacial anomalies, abdominal wall defects, and tumors of the genitourinary tract, liver, adrenal gland, and central nervous system among other abnormalities. (abdominalkey.com)
  • Wilms tumor usually presents as an asymptomatic abdominal mass in an otherwise healthy child. (pedsurglibrary.com)
  • Renal cancer occurs in a sporadic (nonhereditary) and a hereditary form, and both forms are associated with structural alterations of the short arm of chromosome 3 (3p). (medscape.com)
  • We recommended that 13 at-risk individuals from a family with HLRCC should receive active surveillance for early detection of renal cancer. (biomedcentral.com)
  • The development of Wilms tumor has been linked to mutations of the WT1 and WT2 genes located on chromosome 11 at 11p13 and 11p15.5, respectively ( 8 , 9 ). (abdominalkey.com)
  • Therefore, a high detection rate of mutations in HLRCC families may enable early identification of at-risk individuals and allow early initiation of therapy while their tumors are still small. (biomedcentral.com)
  • The tumor was limited to the renal parenchyma, away from sinus fat. (biomedcentral.com)
  • FH encodes an enzyme that is part of the mitochondrial tricarboxylic acid (TCA) cycle involved in cellular energy metabolism and appears to function as a tumor suppressor since its activity is very low or absent in tumors from individuals with HLRCC. (biomedcentral.com)
  • A large hypodense lesion in segment VI of the liver and additional smaller hypodense lesions in the right lobe were also noted. (biomedcentral.com)
  • Spinal neoplastic lesions of metastatic origin severely affect patient quality of life. (123dok.net)
  • The ureteric bud grows laterally and invades the center of the metanephric blastema, the primordial renal tissue [4]. (esur2023.com)
  • Inside the tumor, a white nodule positive for carcinoembryonic antigen, weakly positive for calcitonin, and negative for tyrosine hydroxylase, was identified and diagnosed as a metastatic medullary thyroid carcinoma with high malignant potential. (bvsalud.org)
  • The tumor is usually circumscribed by a pseudocapsule formed of compressed renal and perirenal tissues. (abdominalkey.com)