Metastatic transitional cell carcinoma. Medical search. Frequent questions

citation needed] Presence of an abnormal extra chromosome, classified as a small supernumerary marker chromosome (sSMC), in this malignancy's tumor cells. (wikipedia.org)
Transitional cell carcinomas are often multifocal, with 30-40% of patients having more than one tumor at diagnosis. (wikipedia.org)
The most important and established prognosticators for prostate carcinoma include the Gleason grade, the extent of tumor volume, and the presence of capsular penetration or margin positivity at the time of prostatectomy. (medscape.com)
An immune cell in the tumor microenvironment that may be important for inhibiting the immune response against bladder cancer is the myeloid derived suppressor cell (MDSC). (iospress.com)
Potent antitumoral activity of scFv(FRP5)-ETA against ErbB2-overexpressing tumor cells was previously demonstrated in vitro and in animal models. (uni-frankfurt.de)
Immunotherapy with monoclonal antibodies may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. (bcan.org)
I. To assess for tumor-based biomarkers of response and resistance to this combination therapy using single-cell RNA sequencing (scRNA-seq) and high-dimensional flow cytometry. (bcan.org)
We propose to assess the use of a multiple mutation-based assay, using DNA from exfoliated cells in the urine of patients, to establish the sensitivity and specificity in tumor detection compared to cystoscopy and cytology. (centerwatch.com)
The primary objective of this study is to evaluate the utility of emerging technologies in the detection of bladder tumor cells using non-invasive approaches utilizing voided urine samples. (centerwatch.com)
A receptor tyrosine kinase inhibitor and chemotherapeutic agent used for the treatment of renal cell carcinoma (RCC) and imatinib-resistant gastrointestinal stromal tumor (GIST). (drugbank.com)
This study is to examine the correlation between the impact of lifestyle and tumor grading in Transitional cell carcinoma (TCC). (fortuneonline.org)
Transitional cell carcinoma is a malignant tumor arising from transitional epithelial cells that line the urinary bladder [1]. (fortuneonline.org)
Calcitriol elicits anti-tumor effects mainly through the induction of cancer cell apoptosis, cell cycle arrest, differentiation, angiogenesis and the inhibition of cell invasiveness by a number of mechanisms. (jcancer.org)
The broad spectrum anti-tumor effects of calcitriol and analogs are mostly based on inhibition of cancer cell proliferation and invasiveness, induction of differentiation and apoptosis, and promotion of angiogenesis. (jcancer.org)
Longitudinal assessment of B-RAF V595E levels in the peripheral cell-free tumor DNA of a 10-year-old spayed female Korean Jindo dog with unresectable metastatic urethral transitional cell carcinoma for monitoring the treatment response to a RAF inhibitor (sorafenib). (bvsalud.org)
Staging evaluation revealed no evidence of metastatic disease but at the time of radical cystectomy, periaortic lymphadenopathy and a locally extensive tumor mass were identified. (biomedcentral.com)
The pathology of the tumor was "transitional cell carcinoma" on 27/5/93. (dergisi.org)
Taper showed that vitamin C reactivated DNase II, while vitamin K3 reactivated DNase I with the combination synergistically causing tumor cell death. (theetgtrackclub.com)
Two dogs each developed a Grade II mast cell tumor after 52 and 91 days of APOQUEL administration, respectively. (johnsonvet.com)
This bacterium injects a so-called tumor-inducing (Ti) plasmid in to the place cell, where it integrates in to the genome (Yadav et al. (baxkyardgardener.com)
If are suspected to have clear cell renal cell carcinoma, your doctor will use imaging scans such as X-rays, CT or MRI to look at the size of the tumor. (healthyskinworld.com)
An expert, called a pathologist, will study cells from the sample under the microscope to see what kind of tumor it is. (healthyskinworld.com)
The treatment of non-muscle-invasive bladder cancer (Ta, T1, carcinoma in situ [CIS]) begins with transurethral resection of bladder tumor (TURBT). (medscape.com)

The company's pipeline product candidates include zanzalintinib, XB002 and XL102 for the treatment of advanced or metastatic solid tumors and CBX-12 for advanced metastatic refractory solid tumors. (pharmaceutical-technology.com)
Approximately 90% of malignant tumors arising in the bladder are of epithelial origin, the majority being transitional cell carcinomas. (centerwatch.com)
Clinically, superficial bladder tumors (stages Ta, Tis and T1) account for 75-80% of bladder neoplasms, while the remaining 15-20% are invasive (T2, T3, T4) or metastatic lesions at the time of presentation. (centerwatch.com)
The most common bladder tumors in dogs and cats are transitional cell carcinoma however, in cats the incidence of this disease is very low. (healthybladderclub.com)
We analyzed 223 patients (25 with preinvasive tumors and 198 with invasive and metastatic breast cancers) and 153 noncancer controls. (aacrjournals.org)
Carcinoid tumors and small-cell carcinomas of the gallbladder and extrahepatic bile ducts: a comparative study based on 221 cases from the Surveillance, Epidemiology, and End Results Program. (cancercentrum.se)

Thus, urothelial carcinomas are more common in the context of chronic urinary stone disease, chronic catheterization (as in patients with paraplegia or multiple sclerosis), and chronic infections. (wikipedia.org)
Eltz S, Comperat E, Cussenot O, Rouprêt M. Molecular and histological markers in urothelial carcinomas of the upper urinary tract. (medscape.com)
Lughezzani G, Burger M, Margulis V, Matin SF, Novara G, Roupret M. Prognostic factors in upper urinary tract urothelial carcinomas: a comprehensive review of the current literature. (medscape.com)
They are also known as urothelial carcinomas. (healthyskinworld.com)

The most common type of bladder cancer is urothelial cancer, also known as transitional cell carcinoma, which accounts for 9 out of 10 bladder cancers. (roche.com)
Eighteen patients suffering from ErbB2-expressing metastatic breast cancers, prostate cancers, head and neck cancer, non small cell lung cancer, or transitional cell carcinoma were treated. (uni-frankfurt.de)
Typically, stage 4 or metastatic cancers are classified as distant. (cancercenter.com)
That being said, even more aggressive or metastatic cancers can be treated with the many different treatment options that have become available in recent years. (phoenixcyberknifecenter.com)
Compared to other kidney cancers, the clear cell type of renal cell carcinoma tends to be more aggressive and spread faster. (healthyskinworld.com)
Most primary prostate cancers are aggressive and highly metastatic cancers. (vin.com)
Cancers that have spread from elsewhere in the body are also uncommon but can include lymphoma, which is associated with the immune system, and transitional cell carcinoma, a common cancer found in and around the bladder. (vin.com)
Almost all bladder cancers originate in the urothelium, which is a 3- to 7-cell mucosal layer within the muscular bladder. (medscape.com)
L'ACE et le CA19-9 ont une bonne sensibilité et une spécificité relative qui leur permettent de suivre l'évolution des cancers digestifs en particulier les cancers colorectaux. (bvsalud.org)

The pattern of growth of transitional cell carcinomas can be papillary, sessile, or carcinoma in situ. (wikipedia.org)
Transitional cell carcinomas are mostly papillary (70%, and 30% non-papillary). (wikipedia.org)
The 1973 WHO grading system for transitional cell carcinomas (papilloma, G1, G2 or G3) is most commonly used despite being superseded by the 2004 WHO grading for papillary types (papillary neoplasm of low malignant potential [PNLMP], low grade, and high grade papillary carcinoma). (wikipedia.org)
H&E stain Papillary transitional cell carcinoma, low grade Histopathology of urothelial carcinoma of the urinary bladder, showing a nested pattern of invasion. (wikipedia.org)
Although some of the observed variants, such as chondroid meningiomas, clear-cell meningiomas, papillary meningiomas, and rhabdoid meningiomas, are associated with unfavorable prognoses, the other histologic patterns are not indicators of unfavorable biologic behavior. (medscape.com)

Computerised tomographic (CT) scan of the thorax and abdomen revealed a lesion within the right ventricle (Figure 1 ) without other evidence of metastatic disease within the pulmonary or hepatic parenchyma. (biomedcentral.com)

Epidermal growth factor receptor blockade with C225 modulates proliferation, apoptosis, and radiosensitivity in squamous cell carcinomas of the head and neck. (natprobiotech.com)
Transitional cell and squamous cell carcinomas are the most common but there are three reported cases of mucinous adenocarcinoma. (biomedcentral.com)

50% of dogs eventually develop metastatic disease. (healthybladderclub.com)
however, up to 50% of patients will develop metastatic disease [1, 2]. (cdc.gov)

Ninety percent of all occurrences of bladder cancer are due to Transitional cell carcinoma (TCC), whereas only 5% are due to squamous cell carcinoma, and the remaining 5% include rare subtypes such as adenocarcinoma, sarcoma, and metastatic urothelial cancer [5]. (fortuneonline.org)
The histologic appearance of bladder adenocarcinoma can be enteric, signet ring, mucinous, clear cell, hepatoid and mixed types. (biomedcentral.com)
The differential diagnosis includes glandular differentiation of transitional cell carcinoma and direct extension or metastatic spread of adenocarcinoma arising primarily from the colon, prostate, appendix or endometrium. (biomedcentral.com)
Bladder washings and biopsies revealed copious amounts of mucin with associated malignant nests and single cells also consistent with mucinous adenocarcinoma. (biomedcentral.com)
2: Larengeal poorly differentiated epidermoid carcinoma- Rectal adenocarcinoma. (dergisi.org)

First-line treatment with a combination of nivolumab plus ipilimumab (NIVO + IPI) continues to show long-term survival benefits over sunitinib out to 5 years in patients with advanced clear-cell renal carcinoma (RCC) with sarcomatoid features, according to the CheckMate 214 study presented at GUCS 2022. (mims.com)

It's also known as metastatic kidney cancer. (cancercenter.com)
Stage 4 kidney cancer is when this mass of cancerous cells spreads beyond the layer of fatty tissue around the kidney into the adrenal glands, nearby lymph nodes or other organs. (cancercenter.com)
Metastatic kidney cancer has some specific symptoms that vary from early-stage kidney cancer symptoms . (cancercenter.com)
Metastatic kidney cancer may be difficult to treat. (cancercenter.com)
Treatment for metastatic kidney cancer may depend on the person's age, general health and how far the cancer has spread. (cancercenter.com)
The survival rate for metastatic kidney cancer depends on a variety of factors, including the patient's age, overall health and the extent of the disease. (cancercenter.com)

When the term "urothelial" is used, it specifically refers to a carcinoma of the urothelium, meaning a transitional cell carcinomas of the urinary system. (wikipedia.org)
Phase II studies of single-agent docetaxel (Taxotere) yielded promising results in advanced or metastatic transitional cell carcinoma (TCC) of the urothelium. (cancernetwork.com)
Because of these results, combination Vitamin C and vitamin K3 was granted orphan drug status for the treatment of metastatic or locally advanced, inoperable transitional cell carcinoma of the urothelium (stage III and IV bladder cancer). (theetgtrackclub.com)

Chemotherapy may be used for patients with metastatic prostate cancer, with the aim of slowing any further spread of cancer and improving quality of life. (healthyprostateclub.com)
Interim fluorine-18 fluorodeoxyglucose positron emission tomography for early metabolic assessment of therapeutic response to chemotherapy for metastatic transitional cell carcinoma. (unige.it)
Background: The prognostic impact of early metabolic response by fluorine-18 fluorodeoxyglucose positron emission tomography (FDG-PET) after 2 cycles of first-line chemotherapy is still unrecognized in metastatic transitional cell carcinoma (TCC). (unige.it)
CHICAGO, June 5, 2023 - The Janssen Pharmaceutical Companies of Johnson & Johnson today announced results from an interim analysis of Cohort 1 of the Phase 3 THOR study, evaluating treatment with BALVERSA ® (erdafitinib) versus chemotherapy in patients with metastatic or unresectable urothelial carcinoma (UC) and selected fibroblast growth factor receptor (FGFR) gene alterations who had received prior treatment with an anti-programmed death ligand 1 (PD-[L]1) agent. (janssen.com)

Transitional cell carcinoma, also called urothelial carcinoma, is a type of cancer that typically occurs in the urinary system. (wikipedia.org)
Signs and symptoms of transitional cell carcinomas depend on the location and extent of the cancer. (wikipedia.org)
While advanced prostate cancer was historically defined as distant metastatic disease, the current definition includes disease stages that range from recurrence of prostate-specific antigen (PSA) elevation after failure of local treatment to widespread metastasis. (medscape.com)
Although cure of metastatic prostate cancer remains elusive, continuous advances in management have improved the outlook in these patients. (medscape.com)
The increase in metastatic prostate cancer was greatest (92%) in men aged 55-69 years. (medscape.com)
The 5-year relative survival rate for localized and regional prostate cancer is 100%, compared with 34.1% for metastatic cases. (medscape.com)
Cabometyx is indicated for the treatment of adult and pediatric patients 12 years of age and older with locally advanced or metastatic differentiated thyroid cancer (DTC) that has progressed following prior VEGFR-targeted therapy and who are radioactive iodine-refractory or ineligible. (pharmaceutical-technology.com)
It was also under development for the treatment of relapsed/refractory multiple myeloma, salivary gland, cancer and adenoid cystic carcinoma (ACC). (pharmaceutical-technology.com)
Padcev (enfortumab vedotin-ejfv), an injection drug for intravenous use, was approved by the FDA in December 2019 for the treatment of certain adult patients with locally advanced or metastatic urothelial cancer (mUC). (drug-injury.com)
Treatment patterns and outcomes in metastatic bladder cancer in community oncology settings. (roche.com)
Stable disease was seen in three of the eighteen patients instead of two of the eighteen patients: one patient with transitional cell carcinoma treated at 4 µg/kg scFv(FRP5)-ETA per day, and two breast cancer patients treated at 4 and 12.5 µg/kg scFv(FRP5)-ETA per day. (uni-frankfurt.de)
A middle-aged lady admitted with metastatic breast cancer developed acute respiratory problems with bilateral pulmonary infiltrates after five days of cytotoxic administration, as an acute adverse drug reaction to the docetaxel that resolved completely after high dosage of dexamethasone. (qscience.com)
A chemotherapeutic DNA alkylating agent used in the treatment of metastatic small-cell lung cancer. (drugbank.com)
Transitional cell carcinoma (TCC) is a common type of bladder cancer, predominantly affecting males exposed to certain chemical products and is strongly associated with tobacco consumption. (fortuneonline.org)
Undifferentiated prostate cancer, squamous cell carcinoma, and ductal transitional carcinoma also occur infrequently. (msdmanuals.com)
Targeted therapies are drugs that attack cancer cells based on specific characteristics, such as the proteins they make. (cancercenter.com)
I've spent my career specializing in the care of patients with metastatic urothelial carcinoma and understand the need for new treatments for this disease," said Arlene O. Siefker-Radtke, M.D., professor of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, and lead study investigator. (jnj.com)
Colorectal cancer cell lines were treated with different doses of cetuximab to create ten test groups, which were then incubated for 24 and 48 hours. (natprobiotech.com)
Furthermore, it is possible to say that reducing EGF and KRAS gene expression inhibits cancer cell growth. (natprobiotech.com)
Colorectal cancer cells are resistant to anti-EGFR monoclonal antibody through adapted autophagy. (natprobiotech.com)
BDNF/TrkB signaling protects HT-29 human colon cancer cells from EGFR inhibition. (natprobiotech.com)
Anti-EGFR antibody sensitizes colorectal cancer stem-like cells to Fluorouracil-induced apoptosis by affecting autophagy. (natprobiotech.com)
The use of BALVERSA ® in this setting supports recommendations for FGFR testing in all patients with metastatic urothelial cancer. (janssen.com)
Vitamin C, Vitamin K3 and the combination were evaluated against human bladder cancer cell lines RT-4 and T24 to evaluate their synergistic anticancer activity. (theetgtrackclub.com)
The combination of olaparib and abiraterone in the first-line setting improved radiographic progression-free survival (rPFS) in patients with metastatic castration-resistant prostate cancer (mCRPC), results of the phase III PROpel trial showed. (mims.com)
In patients with metastatic castration-resistant prostate cancer (mCRPC) who experience disease progression while on enzalutamide treatment, continuing enzalutamide appears to improve progression-free survival (PFS), according to results of the phase IIIb PRESIDE trial. (mims.com)
Darolutamide add-on: A new standard of care for metastatic prostate cancer? (mims.com)
Adding darolutamide to androgen-deprivation therapy (ADT) plus docetaxel significantly increases overall survival (OS) in patients with metastatic, hormone-sensitive prostate cancer (mHSPC), according to the ARASENS* trial presented at the ASCO GUCS 2022. (mims.com)
In patients with metastatic castration-resistant prostate cancer (mCRPC) with homologous recombination repair (HRR) gene alterations*, combining niraparib with abiraterone acetate plus prednisone (AAP) in the first-line setting improved radiographic progression-free survival (rPFS) and other outcomes, results of the phase III MAGNITUDE study showed. (mims.com)
Molecular changes which may influence hypercoagulability include the expression of tissue factor (TF) as well as the proteases hepsin and cancer procoagulant by circulating tumour cells [ 4 ]. (biomedcentral.com)
Mutations in DNA Repair Genes and Clinical Outcomes of Patients With Metastatic Colorectal Cancer Receiving Oxaliplatin or Irinotecan-containing Regimens. (bu.edu)
Metastatic cancer is more difficult to treat. (healthyskinworld.com)
The results can confirm a cancer diagnosis and determine whether its the clear cell subtype. (healthyskinworld.com)
Am I at risk for metastatic cancer? (healthyskinworld.com)
A veterinary pathologist will look at the cells from the tissue sample to diagnosis the cancer. (vin.com)
Survival three main types of bladder cancer: transitional cell car- rates varies significantly among age groups. (who.int)
Urothelial (transitional cell) carcinoma is the most patients younger than 50 years to 81.3% in patients older common histological type of bladder cancer, accounting than 50 years (9) . (who.int)
Squamous cell carcinoma ac- rate for 31 266 patients (74% men, 26% women) with counts for about 4% of cases of bladder cancer, adenocar- urinary bladder cancer diagnosed from 1997 to 2011 was cinoma for about 2% and all other types for about 4% of 72% (10) . (who.int)

FORT-2 is designed to evaluate safety, efficacy, RP2D and PK of rogaratinib in combination with atezolizumab in patients with untreated FGFR-positive urothelial carcinoma. (bcan.org)
The primary objective of the Part B is to compare progression-free survival (PFS) according to RECIST v1.1 of rogaratinib in combination with atezolizumab over placebo in combination with atezolizumab in untreated patients with FGFR-positive locally advanced or metastatic urothelial carcinoma. (bcan.org)
Cabometyx is indicated as monotherapy for the treatment of adult patients with locally advanced or metastatic differentiated thyroid carcinoma (DTC), refractory or not eligible to radioactive iodine (RAI) who have progressed during or after prior systemic therapy. (pharmaceutical-technology.com)
Cabometyx (cabozantinib) developed for the treatment of patients with advanced renal cell carcinoma (RCC) and hepatocellular carcinoma (HCC). (pharmaceutical-technology.com)
Purpose: We evaluated the pattern of recurrence and the prognostic factors for patients who suffered with upper urinary tract transitional cell carcinoma (TCCa) and were surgically treated. (elsevierpure.com)
Patients and Methods: Patients with metastatic TCC receiving the modified combination of methotrexate, vinblastine, doxorubicin, and cisplatin (MVAC), according to institutional protocol, underwent computed tomography (CT) and FDG-PET imaging at baseline, a restaging with PET imaging after 2 cycles only (PET2), and a CT (+/- FDG-PET) scan at the end of treatment and during follow-up. (unige.it)
Management of patients with upper urinary tract transitional cell carcinoma. (medscape.com)
Microsatellite instability as predictor of survival in patients with invasive upper urinary tract transitional cell carcinoma. (medscape.com)
Roupret M, Catto J, Coulet F, Azzouzi AR, Amira N, Karmouni T. Microsatellite instability as indicator of MSH2 gene mutation in patients with upper urinary tract transitional cell carcinoma. (medscape.com)
Expression of Ki-67 and COX-2 in patients with upper urinary tract urothelial carcinoma. (medscape.com)
Upper tract urothelial recurrence following radical cystectomy for transitional cell carcinoma of the bladder: an analysis of 1,069 patients with 10-year followup. (medscape.com)
BALVERSA is an important new therapy for this small subset of patients with urothelial carcinoma who, up until now, had limited treatment options. (jnj.com)
These results represent the first data from a randomized, controlled trial evaluating BALVERSA ® for the treatment of patients with FGFR-altered urothelial carcinoma, who often experience poor disease outcomes," said Yohann Loriot*, M.D., Ph.D., Institut Gustave Roussy and University of Paris-Saclay, France, and principal study investigator. (janssen.com)
Lenvatinib + pembrolizumab combination regimen improves progression-free survival (PFS) compared with sunitinib in a subset of East Asian patients with advanced renal cell carcinoma (aRCC), a finding that was similar to that of the global population of the CLEAR* trial, according to a subanalysis presented at ASCO GU 2022. (mims.com)
In the phase II TITAN-TCC* trial presented at ASCO GU 2022, the addition of ipilimumab to nivolumab led to improved responses in patients with pretreated (second/third line) advanced/metastatic or surgically unresectable transitional cell carcinoma (TCC). (mims.com)
Patients who have undergone radical cystectomy require routine surveillance to monitor for local recurrence or the development of metastatic disease. (medscape.com)
Indications for pancreatoduodenectomy in patients undergoing lymphadenectomy for advanced gallbladder carcinoma. (cancercentrum.se)

Histologically or cytologically documented locally advanced/inoperable or metastatic urothelial bladder carcinoma (UBC), including renal pelvis, ureters, urinary bladder, and urethra. (ucsf.edu)
TCCs do not start in the kidney but in the transitional cells in the lining of the renal pelvis. (healthyskinworld.com)

Some particular examples are listed below: Certain drugs, such as cyclophosphamide, via the metabolites acrolein and phenacetin, may predispose to the development of transitional cell carcinomas (the latter especially with respect to the upper urinary tract). (wikipedia.org)
European Association of Urology Guidelines on Upper Urinary Tract Urothelial Carcinoma: 2020 Update. (medscape.com)
Leibl S, Zigeuner R, Hutterer G, Chromecki T, Rehak P, Langner C. EGFR expression in urothelial carcinoma of the upper urinary tract is associated with disease progression and metaplastic morphology. (medscape.com)
Ali O, Fishman E, Sheth S. Upper urinary tract urothelial carcinoma on multidetector CT: spectrum of disease. (medscape.com)
Utility of fluorescence in situ hybridization in the diagnosis of upper urinary tract urothelial carcinoma. (medscape.com)

Transitional cell bladder carcinomas associated with this sSMS are more aggressive and invasive than those not associated with it. (wikipedia.org)

In consequence, the malignant cells bearing it have four copies of this p arm's genetic material, two from each of the normal chromosome 5's and two from the sSMC. (wikipedia.org)
sSMC i(5)(p10)" is the single most common recurrent structural chromosomal abnormality in transitional cell carcinoma, being present in its malignant cells in most cases of the disease. (wikipedia.org)

Epidermal growth factor receptor blockade with C225 plus gemcitabine results in regression of human pancreatic carcinoma growing orthotopically in nude mice by antiangiogenic mechanisms. (natprobiotech.com)
Adjuvant Cisplatin Plus Gemcitabine in Operable Cholangiocellular Carcinoma. (cancercentrum.se)

Histologically document transitional cell carcinoma with the presence of any of the following stages: Carcinoma in situ (CIS), high-grade Ta, any grade T1, or any grade cT2-T4, considered appropriate for radical cystectomy. (bcan.org)

Molecular Genetics and Targeted Therapy in Hepatocellular Carcinoma. (bu.edu)

Dr. Charles Maximus was diagnosed with prostatic transitional cell carcinoma after his owner noticed he was straining to urinate. (healthybladderclub.com)
Immunohistochemical evaluation revealed that neoplastic cells were positive for carcinoembryonic antigen, cytokeratin-7, cytokeratin-20 and were negative for prostate specific antigen and prostatic acid phosphatase. (biomedcentral.com)

One dog developed a low grade oral spindle cell sarcoma after 320 days of APOQUEL administration. (johnsonvet.com)

12 months between the last treatment administration and the date of recurrence is required in order to be considered treatment-naïve in the metastatic setting. (bcan.org)
Factors influencing recurrence after surgical treatment for T2 gallbladder carcinoma. (cancercentrum.se)

No prior systemic treatment for locally advanced or metastatic urothelial carcinoma. (bcan.org)

3: Cervix uteri squamous cell carcinoma- Breast infiltrative ductal carcinoma. (dergisi.org)
4: Hodgkin lymphoma- Breast infiltrative ductal carcinoma. (dergisi.org)

Transitional refers to the histological subtype of the cancerous cells as seen under a microscope. (wikipedia.org)
WHO classifies urothelial carcinoma as low-grade urothelial carcinoma (LGUC) and high-grade urothelial carcinoma (HGUC) based on its cell morphology and histological structure [3, 11]. (fortuneonline.org)

Two tyrosine kinases (Abl Fidarestat (SNK-860) and Fyn) are triggered by DAF clustering and both are required for CVB access into polarized epithelial cells (Coyne and Bergelson 2006). (biotechpatents.org)
Interestingly, Cai2+ release is definitely involved in mediating CVB access into primary human being Rabbit Polyclonal to OR1L8 aortic endothelial cells, but is not required for CVB access into polarized epithelial cells, suggesting the intracellular signaling molecules hijacked by CVB to facilitate access are distinct between the endothelium and epithelium. (biotechpatents.org)
The integrity of limited junctions facilitating bacterial transmigration across polarized airway epithelial cells, similar to the case with replicting rhinoviruses was found to be caused by poly(I:C), i.e. by double stranded RNA. (biotechpatents.org)

Meningiomas , as defined by the 2016 World Health Organization (WHO), are "a group of mostly benign, slow-growing neoplasms that most likely derive from the meningothelial cells of the arachnoid layer. (medscape.com)

Role of p27(Kip1) in human intestinal cell differentiation. (natprobiotech.com)

6th operation was larengectomy and the pathology was "epidermoid carcinoma" on 9/8/93. (dergisi.org)
Pathology was "squamous cell carcinoma" on 14/12/93. (dergisi.org)

Almås B, Halvorsen OJ, Johannesen TB, Beisland C. Higher than expected and significantly increasing incidence of upper tract urothelial carcinoma. (medscape.com)
This would also explain the high incidence of meningiomas around the sagittal sinus, which has a high concentration of meningothelial cells. (medscape.com)

They grade the cells in the biopsy on a scale of 1 to 5. (healthyprostateclub.com)
Brien JC, Shariat SF, Herman MP, Ng CK, Scherr DS, Scoll B. Preoperative hydronephrosis, ureteroscopic biopsy grade and urinary cytology can improve prediction of advanced upper tract urothelial carcinoma. (medscape.com)

For those who are ineligible for cisplatin-based regimens or experience progression of disease, in 2016-2017 the United States Food and Drug Administration approved five monoclonal antibodies that achieve immune checkpoint blockade by targeting the programmed cell death protein-1/programmed death-ligand 1 (PD-1/PD-L1) pathway. (iospress.com)

In individuals with advanced urothelial carcinoma (UC), a first-line maintenance treatment regimen comprising a combination of avelumab and best supportive care (BSC) provided better survival benefit than BSC alone, according to long-term and subgroup analyses of the phase III JAVELIN Bladder 100 trial presented at ASCO GU 2022. (mims.com)

Although meningiomas commonly arise in locations where meningothelial cells are found, the embryonic origin of intraventricular and pulmonary meningiomas are intriguing. (medscape.com)

Anatomy4

Diseases16

Chemicals and Drugs3

Analytical, Diagnostic and Therapeutic Techniques and Equipment6

Disciplines and Occupations1

Tumor23

Tumors6

Urothelial carcinomas4

Cancers9

Papillary5

Evidence of metastatic disease1

Squamous cell carcinomas2

Develop metastatic disease2

Adenocarcinoma5

Clear-cell renal carcinoma1

Kidney cancer6

Urothelium3

Chemotherapy4

Cancer38

Patients17

Renal pelvis2

Urinary tract5

Invasive1

Malignant2

Gemcitabine2

Situ1

Hepatocellular carcinoma1

Prostatic2

Sarcoma1

Recurrence2

Locally1

Ductal2

Histological2

Epithelial cells3

Neoplasms1

Differentiation1

Pathology2

Incidence2

Biopsy2

Regimens1

Survival1

Pulmonary1