• Sister Joseph's nodule is a lymphatic metastasis to the umbilical region. (aafp.org)
  • Sister Joseph (1856-1939), superintendent of St. Mary's Hospital, was credited with making the observation of lymphatic metastases to the umbilical region in metastatic tumors of intra-abdominal origin, hence the name "Sister Joseph's nodule. (aafp.org)
  • 1 Indeed, the primary tumor in most cases of Sister Joseph's nodule is intra-abdominal: stomach, large and small intestine, pancreas, kidney, uterus, ovary or gallbladder. (aafp.org)
  • 2 , 4 In summary, Sister Joseph's nodule is a rare but important clinical finding. (aafp.org)
  • Touraud JP, Lentz N, Dutronc Y, Mercier E, Sagot P, Lambert D. Umbilical cutaneous metastasis (or Sister Mary Joseph's nodule) disclosing an ovarian adenocarcinoma Gynecol Obstet Fertil. (edu.pk)
  • Metastatic nodules of the umbilicus from malignant neoplasms are known as Sister Mary Joseph's nodule and they represent an advanced malignancy. (irispublishers.com)
  • Sister Mary Joseph's Nodule is the name given to the malignant metastatic deposits of the umbilicus. (irispublishers.com)
  • The term "Sister Mary Joseph's Nodule was coined by Sir Hamilton Bailey in his book, Physical Signs in Clinical Surgery, in the honor of Sister Mary Joseph who was a surgical assistant of Dr. William Mayo in the early days of the Mayo Clinic. (irispublishers.com)
  • Six months after surgery, routine follow-up CT revealed the presence of abdominal wall subcutaneous nodules associated with bilateral pulmonary and renal nodules, indicating metastases. (bvsalud.org)
  • We present a case of 56 years old male patient who came to the surgery clinic of our hospital with complains of a recently noticed nodule in the umbilical region. (irispublishers.com)
  • To elucidate the spectrum of metastatic solid tumors to the testis and their clinicopathologic features. (bvsalud.org)
  • The databases and files of 26 pathology departments from 9 countries on 3 continents were surveyed to identify metastatic solid tumors to the testis and to characterize their clinicopathologic features in detail. (bvsalud.org)
  • We compiled a series of 157 cases of metastatic solid tumors that secondarily involved the testis. (bvsalud.org)
  • Patients presenting with umbilical nodules should be investigated without any delay and metastatic nodule should be included in the differential diagnosis especially in elderly patients. (irispublishers.com)
  • Whenever a patient presents to the clinician with umbilical nodule the differential diagnosis includes both benign and malignant conditions. (irispublishers.com)
  • Although generally a poor prognostic sign, long-term survival may be possible if the nodule represents a solitary metastasis. (aafp.org)
  • Palaniappan M, Jose WM, Mehta A, Kumar K, Pavithran K. Umbilical metastasis: a case series of four Sister Joseph nodules from four different visceral malignancies Curr Oncol 2010;17(6):78-81. (edu.pk)
  • The critical indicator of malignancy is usually the appearance of the Sister Mary Joseph Nodule. (wikipedia.org)
  • Metastatic cancer of the umbilicus, known as Sister Mary Joseph nodule, is typically associated with visceral malignancy. (edu.pk)
  • Sister Mary Joseph was the one who identified the relationship between umbilical nodules and advanced intraabdominal malignancy. (irispublishers.com)
  • Sister Mary Joseph nodule associated with pancreatic adenocarcinoma. (edu.pk)
  • An 84-year-old woman presented for evaluation of various benign skin lesions and was incidentally noted to have an 8-mm violaceous nodule in the umbilicus ( Figure 1 ) . (aafp.org)
  • Sister Mary joseph nodule as a presenting sign of pancreatobiliary adenocarcinoma. (edu.pk)
  • The patient had no history of breast cancer, and mammography showed no evidence of breast carcinoma as a primary site for her metastatic disease. (aafp.org)
  • These nodules are mostly adenocarcinomas with the commonest primary sites in intraabdominal organs. (irispublishers.com)
  • The physical examination was nonfocal for a source of metastatic disease. (aafp.org)
  • Additionally, the CT scan revealed two hypodense areas in the liver and a 15-mm nodule in the lower lobe of the right lung, suspicious for metastatic disease. (aafp.org)
  • Sister Mary Joseph nodule-A case report with review of literature. (edu.pk)
  • Physical examination revealed a firm and partially fixed umbilical nodule measuring 2x1.5cms. (irispublishers.com)
  • Metastatic umbilical nodules from lung carcinoma and that too from squamous cell carcinoma are very rare. (irispublishers.com)
  • The study is a summary of the available knowledge on cancerous metastatic lesions of the heart. (bvsalud.org)
  • 9. Fine-needle aspiration cytology of Sister Mary Joseph's (paraumbilical) nodules. (nih.gov)
  • Subcutaneous metastases (referred to as a Sister Mary Joseph nodule or nodules) in the paraumbilical area signify advanced disease. (medscape.com)
  • One skin cancer patient who had metastatic lung tumour refused further conventional treatment after the removal of his skin lesion, he treated himself with Biobran after reading about it online. (healthylivingsg.com)
  • Paule V. Joseph is conducting preclinical, clinical, and translational studies to improve the diagnosis, prevention, and management of chemosensory disorders and symptoms-in chronic conditions such as obesity and type 2 diabetes-by examining the role that smell and taste play in those conditions. (nih.gov)
  • A resection of the umbilical nodule was discussed but the patient unfortunately died following a massive pulmonary embolism. (journalmc.org)