• Wilms tumor, treatment for which includes surgery (radical or partial nephrectomy), is the fifth most common pediatric malignancy and the most common type of renal tumor in children. (medscape.com)
  • In patients with bilateral Wilms tumors, solitary kidney, or kidney insufficiency, partial nephrectomy is a reasonable consideration. (medscape.com)
  • The role of partial nephrectomy remains controversial. (medscape.com)
  • Partial nephrectomy may be feasible in only 10%-15% of patients, as most tumors are too large at initial diagnosis. (medscape.com)
  • The NWTS-4 study showed an 8% local recurrence rate following partial nephrectomy for patients with bilateral disease. (medscape.com)
  • 3] In the presence of bilateral Wilms tumors, solitary kidney, or renal insufficiency, partial nephrectomy is a reasonable consideration. (medscape.com)
  • To summarize the available evidence on renorrhaphy techniques and to assess their impact on peri‐operative outcomes after minimally invasive partial nephrectomy (MIPN). (bjuinternational.com)
  • Studies providing sufficient details on renorrhaphy techniques during laparoscopic or robot‐assisted partial nephrectomy and comparative studies focused on peri‐operative outcomes were included in qualitative and quantitative analyses, respectively. (bjuinternational.com)
  • Integrated overview of evidence‐based technical principles for renal reconstruction during minimally invasive partial nephrectomy and suggested standardized reporting of key renorrhaphy features in clinical studies on this topic. (bjuinternational.com)
  • To determine the scope and outcomes of nephron-sparing surgery (NSS), i.e. partial nephrectomy, across the UK and in so doing set a realistic benchmark and identify fresh contemporary challenges in NSS. (bjuinternational.com)
  • Contraindications to primary surgery for Wilms tumor include bilateral tumors and documented metastatic disease. (medscape.com)
  • Large tumors that extend beyond the midline, have vascular extension, or both are relative contraindications, since some surgeons elect to obtain tissue via surgical excision, but this may expose patients to increased surgical risks. (medscape.com)
  • Differential diagnoses in radiologic studies include local abscess, granuloma, xanthogranulomatous pyelonephritis, lymphoma and multifocal primary or metastatic tumors [8]. (buyresearchchemicalss.net)
  • Renal malakoplakia may imitate renal lead and tumors to needless surgery. (buyresearchchemicalss.net)
  • Local recurrence and metastatic tumors may occur in up to 10% of cases. (cap.org)
  • These tumors oftentimes have a highly irregular interface with the kidney parenchyma and have fascicles of tumor cells interlacing with renal parenchyma. (cap.org)
  • Synovial sarcoma and sarcomatoid renal cell carcinoma may be indistinguishable on pure histologie and immunohistochemical grounds, but these tumors contain distinctly different sets of chromosomal abnormalities. (the-medical-dictionary.com)
  • Fifteen of the 16 previous cases of primary renal SS were diagnosed using reverse-transcription polymerase chain reaction to detect the SYT-SSX gene fusion transcript caused by the t(X;18) translocation,2,3 whereas in the one remaining case a t(X;18) translocation was identified by cytogenetic analysis but no further karyotypic details were published.2 Therefore, the background cytogenetic profile of these tumors was unknown. (the-medical-dictionary.com)
  • The classification of epithelial tumors of the kidney has in particular undergone substantial progress in the last two decades with major contributions from genetic typing of renal cell carcinomas (RCCs). (abdominalkey.com)
  • The role of genotyping and ancillary tools, in particular immunohistochemistry, in correctly classifying these tumors is highlighted in the section on Renal Cell Carcinoma. (abdominalkey.com)
  • More than 80% of renal tumors of childhood are Wilms tumor (nephroblastoma) ( 1 , 2 ). (abdominalkey.com)
  • Wilms tumor is rare in adults, accounting for only 0.5% of renal lesions. (medscape.com)
  • Gross nephrectomy specimen shows a Wilms tumor pushing the normal renal parenchyma to the side. (medscape.com)
  • Wilms tumor arises from the primitive embryonal renal tissue. (medscape.com)
  • Grossly, Wilms tumor is typically an intrarenal solid or cystic mass, which may displace and, in rare cases, invade the renal collecting system. (medscape.com)
  • The tumor extends into the renal vein in 40% of cases. (medscape.com)
  • According to the NWTSG protocol, the first step in the treatment of Wilms tumor is surgical staging followed by radical nephrectomy, if possible. (medscape.com)
  • Other genetically linked conditions also increase the risk of RCC, including hereditary papillary renal carcinoma, hereditary leiomyomatosis, Birt-Hogg-Dube syndrome, hyperparathyroidism-jaw tumor syndrome, familial papillary thyroid carcinoma, von Hippel-Lindau disease and sickle cell disease. (wikipedia.org)
  • A left renal mass was detected on computerized tomography (CT) scan followed by a histopathological diagnosis of MTSCC with 70% tumor showing the sarcomatoid change. (biomedcentral.com)
  • The tumor was limited to the renal parenchyma, away from sinus fat. (biomedcentral.com)
  • The tumor was found to be focally invading into the perinephric fat, beyond the renal capsule. (biomedcentral.com)
  • The patient inside our survey Gemcitabine HCl novel inhibtior acquired renal malakoplakia but underwent a nephrectomy using the scientific medical diagnosis of a renal tumor. (buyresearchchemicalss.net)
  • The scientific impression was a renal tumor or xanthogranulomatous pyelonephritis. (buyresearchchemicalss.net)
  • 7, 8] A complete surgical procedure can be performed by laparoscopy when the tumor is small, allowing a first approach to the renal vessels without mobilization of the kidney. (medscape.com)
  • A three-year old child presents with a large renal mass suspected to be a Wilms tumor. (pedsurglibrary.com)
  • Surgical resection is performed and pathologic evaluation shows completely resected Wilms tumor with focal penetration of the renal capsule. (pedsurglibrary.com)
  • b) blood vessels within the specimen outside of the parenchyma contain tumor. (pedsurglibrary.com)
  • Bilateral renal involvement by tumor is present at diagnosis. (pedsurglibrary.com)
  • Children with which of the following conditions should receive screening renal ultrasounds for nephroblastoma (Wilms tumor)? (pedsurglibrary.com)
  • When this occurs, origin of this unusual tumor type has been the subject of debate in the literature, with a suggestion that previously reported cases may be more correctly described as renal cell carcinoma with sarcomatoid dedifferentiation. (the-medical-dictionary.com)
  • Most previous cases of primary renal synovial sarcoma were confirmed by molecular biology techniques, which detected the SYT-SSX gene fusion transcript typical of this tumor, but no details of the other chromosomal anomalies have been published. (the-medical-dictionary.com)
  • The tumor is usually circumscribed by a pseudocapsule formed of compressed renal and perirenal tissues. (abdominalkey.com)
  • There are various types of renal cell carcinomas with distinct underlying molecular features, unique immunophenotypes, varying degrees of clinical outcomes, and therapeutic implications. (biomedcentral.com)
  • Although end-stage kidney disease after unilateral radical nephrectomy is uncommon (0.25% in the NWTSG trial), preserving healthy kidney tissue may prevent this complication, especially in patients with an underlying intrinsic kidney disease (eg, WAGR [Wilms tumor, aniridia, genitourinary anomalies, and mental retardation] syndrome, Denys-Drash syndrome). (medscape.com)
  • Renal cell carcinoma (RCC) is a kidney cancer that originates in the lining of the proximal convoluted tubule, a part of the very small tubes in the kidney that transport primary urine. (wikipedia.org)
  • A case of a 23-year-old male is discussed with an incidental renal mass in the left kidney after a workup of bilateral flank pain. (biomedcentral.com)
  • Commonly, multiple poorly defined renal lesions enlarging the kidney, and often involving both kidneys, are present. (buyresearchchemicalss.net)
  • In addition, preliminary but encouraging data indicate that a laparoscopic approach to nephrectomy in benign disease is associated with decreased lengths of hospital stay and analgesic requirements in the pediatric patient. (medscape.com)
  • A large hypodense lesion in segment VI of the liver and additional smaller hypodense lesions in the right lobe were also noted. (biomedcentral.com)
  • The renal lesions can distort the pelvis and calices but seldom cause obstruction. (buyresearchchemicalss.net)
  • Focal renal lesions are usually poorly defined and hypoechoic on ultrasound study. (buyresearchchemicalss.net)
  • If imaging studies demonstrate bilateral disease, nephrectomy is not performed, but biopsy specimens are obtained. (medscape.com)
  • Vessels of renal sinus not involved. (pedsurglibrary.com)
  • Specific tumour features (i.e. size, hilar location, anatomical complexity, nearness to renal sinus and/or urinary collecting system), surgeon's experience, robot‐assisted technology, as well as the aim of reducing warm ischaemia time and the amount of devascularized renal parenchyma preserved represented the key factors driving the evolution of the renorrhaphy techniques during MIPN over the past decade. (bjuinternational.com)
  • Congenital mesoblastic nephroma represents approximately 2-4% of all pediatric renal neoplasms. (cap.org)
  • Multiple enlarged upper abdominal and left renal hilar lymph nodes were seen. (biomedcentral.com)
  • In wake of complete clinical, laboratory, and radiological assessment left radical nephrectomy and adrenalectomy with lymph node dissection was performed. (biomedcentral.com)
  • Gross inspection of the lesion discloses gentle tan-yellow homogenous plaques and confluent nodules that are often significantly less than 1cm in size but can range up to 3 to 4cm and replace huge regions of renal Gemcitabine HCl novel inhibtior parenchyma. (buyresearchchemicalss.net)
  • CT scan chest showed tiny pulmonary nodules suspicious to be metastatic. (biomedcentral.com)
  • The large, rapidly Gemcitabine HCl novel inhibtior growing nodules of malakoplakia may mimic renal cell carcinoma in imaging studies. (buyresearchchemicalss.net)
  • The tumour arises from the cells of the proximal renal tubular epithelium. (wikipedia.org)
  • If primary renal SS is indeed a form of sarcomatoid differentiation that arises from renal cell carcinoma (RCC), then it is reasonable to expect that the t(X;18)(p11.2:q11.2) translocation associated with the SS phenotype would occur within a cytogenetic profile characteristic of the underlying RCC subtype. (the-medical-dictionary.com)
  • The ureteric bud divides and branches forming the collecting system (renal pelvis, infundibulae, calyces, and tubules) for urine drainage. (esur2023.com)
  • Mucinous tubular and spindle cell carcinoma (MTSCC) is a type of renal cell carcinoma (RCC) described as an entity with low-grade and low malignant potential. (biomedcentral.com)
  • A unifocal renal lesion is usually uncommon and can resemble a necrotic renal cell carcinoma [1]. (buyresearchchemicalss.net)
  • Conclusion Renal malakoplakia must be kept in mind for patients presenting with a renal mass and a history of long-term recurrent renal infections or renal failure. (buyresearchchemicalss.net)
  • PURPOSE: This retrospective, multicenter study analyzes the efficacy and safety of stereotactic body radiation therapy in a large cohort of patients with oligometastatic/persistent/recurrent uterine cancer. (bvsalud.org)
  • Your urologist may arrange an ultrasound (USS) of the renal tract to assess the kidneys and and perform a flexible cystoscopy to exclude any other causes for the symptoms within the bladder. (essexurology.co.uk)
  • He has dedicated his clinical practice to the surgical management of metastatic disease, particularly to the liver and peritoneum. (stanford.edu)
  • The authors are to be congratulated in bringing these data to publication to provoke debate on the treatment paradigm for small renal masses (SRMs) by reviewing nationally collected data on the main therapeutic surgical option: nephron-sparing surgery. (bjuinternational.com)
  • Involvement of the renal vasculature is not identified. (cap.org)
  • In all, 14% (894/6 042) of the patients underwent surgery for T1a tumours: 55% (488/894) by NSS, 42% (377/894) by radical nephrectomy (RN), and in 3% (29/894) the procedure used was unknown. (bjuinternational.com)
  • This classic triad is 1: haematuria, which is when there is blood present in the urine, 2: flank pain, which is pain on the side of the body between the hip and ribs, and 3: an abdominal mass, similar to bloating but larger. (wikipedia.org)
  • The ureteric bud grows laterally and invades the center of the metanephric blastema, the primordial renal tissue [4]. (esur2023.com)
  • Following physical and radiologic examinations, the child undergoes a left radical nephrectomy. (cap.org)
  • diagnosis was renal malakoplakia. (buyresearchchemicalss.net)
  • The medical diagnosis of malakoplakia should be considered for patients delivering using a renal mass and NOTCH1 a brief history of long-term repeated renal attacks or renal failing [4]. (buyresearchchemicalss.net)
  • A nephrectomy could be a choice for unifocal malakoplakia, however the preoperative medical diagnosis of renal malakoplakia in suitable scientific configurations can prevent needless surgery. (buyresearchchemicalss.net)
  • Limitations included poor reporting of renal function data and no data on tumour complexity. (bjuinternational.com)
  • Since this is a relatively rare type of cancer, large studies haven't been conducted, but, from the number of cases reported, there is usually a swelling around the affected area, and often there is pain or discomfort (however, some patients can have no pain or discomfort at all). (the-medical-dictionary.com)
  • As anyone who has attended a renal multidisciplinary meeting can testify, the predominant presentation of renal cancer is the incidentally detected SRM, often in elderly patients with significant comorbidity. (bjuinternational.com)
  • Succinate dehydrogenase-deficient (SDH-deficient) renal cell carcinoma (RCC) is a rare subtype of RCC. (sajo.org.za)
  • Succinate dehydrogenase- (SDH)-deficient renal cell carcinoma (RCC) is a rare subtype of RCC, estimated to comprise 0.05% - 0.2% of all cases of RCC globally. (sajo.org.za)
  • It is now known that this classic triad of symptoms only occurs in 10-15% of cases, and is usually indicative that the renal cell carcinoma (RCC) is in an advanced stage. (wikipedia.org)
  • CT scan (Fig. 1 ) abdomen showed well-defined heterogeneously relatively hypo-enhancing, ball-shaped, left renal mass with loss of fat interface with adjacent large bowel, compressing and displacing pelvicalyceal system with no definite vascular extension. (biomedcentral.com)
  • All the hematological investigations including renal function tests were within normal limits. (biomedcentral.com)
  • VVe present a case of primary renal SS assessed by standard cytogenetic analysis, which confirms a karyotype that is characteristic of SS as opposed to RCC with or without further genetic aberrations. (the-medical-dictionary.com)
  • Immunotherapy and targeted therapy have improved the outlook for metastatic RCC. (wikipedia.org)
  • The increase in demand for medical care for renal complications associated with neoplastic diseases is a reality in most nephrology departments. (revistanefrologia.com)